메뉴 건너뛰기




Volumn 46, Issue 4, 2012, Pages 339-348

Conceptualizing withdrawal-induced escalation of alcohol self-administration as a learned, plasticity-dependent process

Author keywords

Anxiety; Dependence; Dynorphin; Extended Amygdala; Extracellular matrix; Kappa opioid receptor; Matrix metalloproteinase; Negative reinforcement; Nucleus accumbens; Stress

Indexed keywords

DYNORPHIN; KAPPA OPIATE RECEPTOR; MATRIX METALLOPROTEINASE;

EID: 84861199710     PISSN: 07418329     EISSN: 18736823     Source Type: Journal    
DOI: 10.1016/j.alcohol.2012.01.001     Document Type: Review
Times cited : (20)

References (126)
  • 2
    • 0004235298 scopus 로고    scopus 로고
    • American Psychiatric Association, Washington, DC, American Psychiatric Association
    • American Psychiatric Association Diagnostic and statistical manual of mental disorders DSM-IV 1994, American Psychiatric Association, Washington, DC. 4th ed.
    • (1994) Diagnostic and statistical manual of mental disorders DSM-IV
  • 3
    • 0004235298 scopus 로고    scopus 로고
    • American Psychiatric Association, Washington, DC, American Psychiatric Association
    • American Psychiatric Association Diagnostic and statistical manual of mental disorders DSM-IV-TR 2000, American Psychiatric Association, Washington, DC. 4th ed., text revision ed.
    • (2000) Diagnostic and statistical manual of mental disorders DSM-IV-TR
  • 7
    • 33751194248 scopus 로고    scopus 로고
    • Effect of duration and pattern of chronic ethanol exposure on tolerance to the discriminative stimulus effects of ethanol in C57BL/6J mice
    • Becker H.C., Baros A.M. Effect of duration and pattern of chronic ethanol exposure on tolerance to the discriminative stimulus effects of ethanol in C57BL/6J mice. Journal of Pharmacology and Experimental Therapeutics 2006, 319:871-878.
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.319 , pp. 871-878
    • Becker, H.C.1    Baros, A.M.2
  • 8
    • 0025137874 scopus 로고
    • Evidence for the rewarding effects of ethanol using the conditioned place preference method
    • Bozarth M.A. Evidence for the rewarding effects of ethanol using the conditioned place preference method. Pharmacology Biochemistry and Behaviour 1990, 35:485-487.
    • (1990) Pharmacology Biochemistry and Behaviour , vol.35 , pp. 485-487
    • Bozarth, M.A.1
  • 9
    • 79960640947 scopus 로고    scopus 로고
    • Chronic intermittent ethanol exposure in early adolescent and adult male rats: effects on tolerance, social behavior, and ethanol intake
    • Broadwater M., Varlinskaya E.I., Spear L.P. Chronic intermittent ethanol exposure in early adolescent and adult male rats: effects on tolerance, social behavior, and ethanol intake. Alcoholism: Clinical and Experimental Research 2011, 35:1392-1403.
    • (2011) Alcoholism: Clinical and Experimental Research , vol.35 , pp. 1392-1403
    • Broadwater, M.1    Varlinskaya, E.I.2    Spear, L.P.3
  • 10
    • 33947642699 scopus 로고    scopus 로고
    • Role of matrix metalloproteinases in the acquisition and reconsolidation of cocaine-induced conditioned place preference
    • Brown T.E., Forquer M.R., Cocking D.L., Jansen H.T., Harding J.W., Sorg B.A. Role of matrix metalloproteinases in the acquisition and reconsolidation of cocaine-induced conditioned place preference. Learning & Memory 2007, 14:214-223.
    • (2007) Learning & Memory , vol.14 , pp. 214-223
    • Brown, T.E.1    Forquer, M.R.2    Cocking, D.L.3    Jansen, H.T.4    Harding, J.W.5    Sorg, B.A.6
  • 11
    • 56549109226 scopus 로고    scopus 로고
    • Increase in matrix metalloproteinase-9 levels in the rat medial prefrontal cortex after cocaine reinstatement of conditioned place preference
    • Brown T.E., Forquer M.R., Harding J.W., Wright J.W., Sorg B.A. Increase in matrix metalloproteinase-9 levels in the rat medial prefrontal cortex after cocaine reinstatement of conditioned place preference. Synapse 2008, 62:886-889.
    • (2008) Synapse , vol.62 , pp. 886-889
    • Brown, T.E.1    Forquer, M.R.2    Harding, J.W.3    Wright, J.W.4    Sorg, B.A.5
  • 12
    • 58749106246 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinase activity disrupts reconsolidation but not consolidation of a fear memory
    • Brown T.E., Wilson A.R., Cocking D.L., Sorg B.A. Inhibition of matrix metalloproteinase activity disrupts reconsolidation but not consolidation of a fear memory. Neurobiology of Learning and Memory 2009, 91:66-72.
    • (2009) Neurobiology of Learning and Memory , vol.91 , pp. 66-72
    • Brown, T.E.1    Wilson, A.R.2    Cocking, D.L.3    Sorg, B.A.4
  • 13
    • 0036062627 scopus 로고    scopus 로고
    • Nucleus accumbens cell firing during goal-directed behaviors for cocaine vs. 'natural' reinforcement
    • Carelli R.M. Nucleus accumbens cell firing during goal-directed behaviors for cocaine vs. 'natural' reinforcement. Physiology & Behaviour 2002, 76:379-387.
    • (2002) Physiology & Behaviour , vol.76 , pp. 379-387
    • Carelli, R.M.1
  • 17
    • 33847292937 scopus 로고    scopus 로고
    • Chronic ethanol consumption increases dopamine uptake in the nucleus accumbens of high alcohol drinking rats
    • Carroll M.R., Rodd Z.A., Murphy J.M., Simon J.R. Chronic ethanol consumption increases dopamine uptake in the nucleus accumbens of high alcohol drinking rats. Alcohol 2006, 40:103-109.
    • (2006) Alcohol , vol.40 , pp. 103-109
    • Carroll, M.R.1    Rodd, Z.A.2    Murphy, J.M.3    Simon, J.R.4
  • 18
    • 0034028920 scopus 로고    scopus 로고
    • Effect of chronic ethanol and withdrawal on the mu-opioid receptor- and 5-Hydroxytryptamine(1A) receptor-stimulated binding of [(35)S]Guanosine-5'-O-(3-thio)triphosphate in the fawn-hooded rat brain: a quantitative autoradiography study
    • Chen F., Lawrence A.J. Effect of chronic ethanol and withdrawal on the mu-opioid receptor- and 5-Hydroxytryptamine(1A) receptor-stimulated binding of [(35)S]Guanosine-5'-O-(3-thio)triphosphate in the fawn-hooded rat brain: a quantitative autoradiography study. Journal of Pharmacology and Experimental Therapeutics 2000, 293:159-165.
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.293 , pp. 159-165
    • Chen, F.1    Lawrence, A.J.2
  • 20
    • 0343933624 scopus 로고
    • Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
    • Di Chiara G., Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proceedings of the National Academy of Sciences of the United States of America 1988, 85:5274-5278.
    • (1988) Proceedings of the National Academy of Sciences of the United States of America , vol.85 , pp. 5274-5278
    • Di Chiara, G.1    Imperato, A.2
  • 21
    • 70449706393 scopus 로고    scopus 로고
    • Extracellular matrix in plasticity and epileptogenesis
    • Dityatev A., Fellin T. Extracellular matrix in plasticity and epileptogenesis. Neuron Glia Biology 2008, 4:235-247.
    • (2008) Neuron Glia Biology , vol.4 , pp. 235-247
    • Dityatev, A.1    Fellin, T.2
  • 22
    • 33747067938 scopus 로고    scopus 로고
    • Kappa-opioid receptor modulation of accumbal dopamine concentration during operant ethanol self-administration
    • Doyon W.M., Howard E.C., Shippenberg T.S., Gonzales R.A. Kappa-opioid receptor modulation of accumbal dopamine concentration during operant ethanol self-administration. Neuropharmacology 2006, 51:487-496.
    • (2006) Neuropharmacology , vol.51 , pp. 487-496
    • Doyon, W.M.1    Howard, E.C.2    Shippenberg, T.S.3    Gonzales, R.A.4
  • 24
    • 34547957954 scopus 로고    scopus 로고
    • Matrix metalloproteinases in brain development and remodeling: synaptic functions and targets
    • Ethell I.M., Ethell D.W. Matrix metalloproteinases in brain development and remodeling: synaptic functions and targets. Journal of Neuroscience Research 2007, 85:2813-2823.
    • (2007) Journal of Neuroscience Research , vol.85 , pp. 2813-2823
    • Ethell, I.M.1    Ethell, D.W.2
  • 25
    • 0024391910 scopus 로고
    • Flumazenil but not nitrendipine reverses the increased anxiety during ethanol withdrawal in the rat
    • File S.E., Baldwin H.A., Hitchcott P.K. Flumazenil but not nitrendipine reverses the increased anxiety during ethanol withdrawal in the rat. Psychopharmacology (Berlin) 1989, 98:262-264.
    • (1989) Psychopharmacology (Berlin) , vol.98 , pp. 262-264
    • File, S.E.1    Baldwin, H.A.2    Hitchcott, P.K.3
  • 26
    • 36448943262 scopus 로고    scopus 로고
    • Chronic ethanol exposure inhibits dopamine release via effects on the presynaptic actin cytoskeleton in PC12 cells
    • Funk C.K., Dohrman D.P. Chronic ethanol exposure inhibits dopamine release via effects on the presynaptic actin cytoskeleton in PC12 cells. Brain Research 2007, 1185:86-94.
    • (2007) Brain Research , vol.1185 , pp. 86-94
    • Funk, C.K.1    Dohrman, D.P.2
  • 27
    • 33750931628 scopus 로고    scopus 로고
    • Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats
    • Funk C.K., O'Dell L.E., Crawford E.F., Koob G.F. Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats. Journal of Neuroscience 2006, 26:11324-11332.
    • (2006) Journal of Neuroscience , vol.26 , pp. 11324-11332
    • Funk, C.K.1    O'Dell, L.E.2    Crawford, E.F.3    Koob, G.F.4
  • 28
    • 84861188676 scopus 로고    scopus 로고
    • Ockham's razor and its improper use
    • Gernert D. Ockham's razor and its improper use. Cognitive Systems 2009, 7:133-138.
    • (2009) Cognitive Systems , vol.7 , pp. 133-138
    • Gernert, D.1
  • 29
    • 0029983167 scopus 로고    scopus 로고
    • Enhanced sensitivity of pituitary beta-endorphin to ethanol in subjects at high risk of alcoholism
    • Gianoulakis C., Krishnan B., Thavundayil J. Enhanced sensitivity of pituitary beta-endorphin to ethanol in subjects at high risk of alcoholism. Archives of General Psychiatry 1996, 53:250-257.
    • (1996) Archives of General Psychiatry , vol.53 , pp. 250-257
    • Gianoulakis, C.1    Krishnan, B.2    Thavundayil, J.3
  • 31
    • 41949114582 scopus 로고    scopus 로고
    • Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions
    • Healey J.C., Winder D.G., Kash T.L. Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions. Alcohol 2008, 42:179-190.
    • (2008) Alcohol , vol.42 , pp. 179-190
    • Healey, J.C.1    Winder, D.G.2    Kash, T.L.3
  • 32
    • 33746325472 scopus 로고    scopus 로고
    • Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms
    • Heilig M., Egli M. Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacology & Therapeutics 2006, 111:855-876.
    • (2006) Pharmacology & Therapeutics , vol.111 , pp. 855-876
    • Heilig, M.1    Egli, M.2
  • 33
    • 76749117168 scopus 로고    scopus 로고
    • Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked?
    • Heilig M., Egli M., Crabbe J.C., Becker H.C. Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked?. Addiction Biology 2010, 15:169-184.
    • (2010) Addiction Biology , vol.15 , pp. 169-184
    • Heilig, M.1    Egli, M.2    Crabbe, J.C.3    Becker, H.C.4
  • 34
    • 0031037561 scopus 로고    scopus 로고
    • Endogenous opioid systems and alcohol addiction
    • Herz A. Endogenous opioid systems and alcohol addiction. Psychopharmacology (Berlin) 1997, 129:99-111.
    • (1997) Psychopharmacology (Berlin) , vol.129 , pp. 99-111
    • Herz, A.1
  • 35
    • 34948899870 scopus 로고    scopus 로고
    • Microscopic polyangiitis and myasthenia gravis: the battle of Occam and Hickam
    • Holmes M.V., Sen D. Microscopic polyangiitis and myasthenia gravis: the battle of Occam and Hickam. Clinical Rheumatology 2007, 26:1981-1983.
    • (2007) Clinical Rheumatology , vol.26 , pp. 1981-1983
    • Holmes, M.V.1    Sen, D.2
  • 37
    • 0035125031 scopus 로고    scopus 로고
    • Suppression of ethanol responding by centrally administered CTOP and naltrindole in AA and Wistar rats
    • Hyytia P., Kiianmaa K. Suppression of ethanol responding by centrally administered CTOP and naltrindole in AA and Wistar rats. Alcoholism: Clinical and Experimental Research 2001, 25:25-33.
    • (2001) Alcoholism: Clinical and Experimental Research , vol.25 , pp. 25-33
    • Hyytia, P.1    Kiianmaa, K.2
  • 39
    • 66549117005 scopus 로고    scopus 로고
    • Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area
    • Jarjour S., Bai L., Gianoulakis C. Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area. Alcoholism: Clinical and Experimental Research 2009, 33:1033-1043.
    • (2009) Alcoholism: Clinical and Experimental Research , vol.33 , pp. 1033-1043
    • Jarjour, S.1    Bai, L.2    Gianoulakis, C.3
  • 40
    • 0015126986 scopus 로고
    • Tolerance to, and dependence on, some non-opiate psychotropic drugs
    • Kalant H., LeBlanc A.E., Gibbins R.J. Tolerance to, and dependence on, some non-opiate psychotropic drugs. Pharmacological Reviews 1971, 23:135-191.
    • (1971) Pharmacological Reviews , vol.23 , pp. 135-191
    • Kalant, H.1    LeBlanc, A.E.2    Gibbins, R.J.3
  • 42
    • 28444442694 scopus 로고    scopus 로고
    • Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward
    • Kelley A.E., Baldo B.A., Pratt W.E., Will M.J. Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward. Physiology & Behaviour 2005, 86:773-795.
    • (2005) Physiology & Behaviour , vol.86 , pp. 773-795
    • Kelley, A.E.1    Baldo, B.A.2    Pratt, W.E.3    Will, M.J.4
  • 43
    • 0033913561 scopus 로고    scopus 로고
    • Neurobiology of addiction. Toward the development of new therapies
    • Koob G.F. Neurobiology of addiction. Toward the development of new therapies. Annals of the New York Academy of Sciences 2000, 909:170-185.
    • (2000) Annals of the New York Academy of Sciences , vol.909 , pp. 170-185
    • Koob, G.F.1
  • 44
    • 4644342311 scopus 로고    scopus 로고
    • A role for GABA mechanisms in the motivational effects of alcohol
    • Koob G.F. A role for GABA mechanisms in the motivational effects of alcohol. Biochemical Pharmacology 2004, 68:1515-1525.
    • (2004) Biochemical Pharmacology , vol.68 , pp. 1515-1525
    • Koob, G.F.1
  • 45
    • 70449628050 scopus 로고    scopus 로고
    • Dynamics of neuronal circuits in addiction: reward, antireward, and emotional memory
    • Koob G.F. Dynamics of neuronal circuits in addiction: reward, antireward, and emotional memory. Pharmacopsychiatry 2009, 42(Suppl 1):S32-S41.
    • (2009) Pharmacopsychiatry , vol.42 , Issue.SUPPL. 1
    • Koob, G.F.1
  • 46
    • 58049147045 scopus 로고    scopus 로고
    • Neurobiological substrates for the dark side of compulsivity in addiction
    • Koob G.F. Neurobiological substrates for the dark side of compulsivity in addiction. Neuropharmacology 2009, 56(Suppl 1):18-31.
    • (2009) Neuropharmacology , vol.56 , Issue.SUPPL. 1 , pp. 18-31
    • Koob, G.F.1
  • 47
    • 0023763088 scopus 로고
    • Cellular and molecular mechanisms of drug dependence
    • Koob G.F., Bloom F.E. Cellular and molecular mechanisms of drug dependence. Science 1988, 242:715-723.
    • (1988) Science , vol.242 , pp. 715-723
    • Koob, G.F.1    Bloom, F.E.2
  • 48
    • 0030756351 scopus 로고    scopus 로고
    • Drug abuse: hedonic homeostatic dysregulation
    • Koob G.F., Le Moal M. Drug abuse: hedonic homeostatic dysregulation. Science 1997, 278:52-58.
    • (1997) Science , vol.278 , pp. 52-58
    • Koob, G.F.1    Le Moal, M.2
  • 49
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • Koob G.F., Le Moal M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 2001, 24:97-129.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 51
    • 0026444211 scopus 로고
    • Neuropharmacology of cocaine and ethanol dependence
    • Koob G.F., Weiss F. Neuropharmacology of cocaine and ethanol dependence. Recent Developments in Alcoholism 1992, 10:201-233.
    • (1992) Recent Developments in Alcoholism , vol.10 , pp. 201-233
    • Koob, G.F.1    Weiss, F.2
  • 52
    • 56349120585 scopus 로고    scopus 로고
    • Effects of acute ethanol on opioid peptide release in the central amygdala: an in vivo microdialysis study
    • Lam M.P., Marinelli P.W., Bai L., Gianoulakis C. Effects of acute ethanol on opioid peptide release in the central amygdala: an in vivo microdialysis study. Psychopharmacology (Berlin) 2008, 201:261-271.
    • (2008) Psychopharmacology (Berlin) , vol.201 , pp. 261-271
    • Lam, M.P.1    Marinelli, P.W.2    Bai, L.3    Gianoulakis, C.4
  • 53
    • 38349031157 scopus 로고    scopus 로고
    • The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system
    • Land B.B., Bruchas M.R., Lemos J.C., Xu M., Melief E.J., Chavkin C. The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system. Journal of Neuroscience 2008, 28:407-414.
    • (2008) Journal of Neuroscience , vol.28 , pp. 407-414
    • Land, B.B.1    Bruchas, M.R.2    Lemos, J.C.3    Xu, M.4    Melief, E.J.5    Chavkin, C.6
  • 54
    • 70449709485 scopus 로고    scopus 로고
    • Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules
    • Lee T.W., Tsang V.W., Birch N.P. Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules. Neuron Glia Biology 2008, 4:223-234.
    • (2008) Neuron Glia Biology , vol.4 , pp. 223-234
    • Lee, T.W.1    Tsang, V.W.2    Birch, N.P.3
  • 55
    • 0035069017 scopus 로고    scopus 로고
    • Voluntary ethanol drinking in C57BL/6J and DBA/2J mice before and after sensitization to the locomotor stimulant effects of ethanol
    • Lessov C.N., Palmer A.A., Quick E.A., Phillips T.J. Voluntary ethanol drinking in C57BL/6J and DBA/2J mice before and after sensitization to the locomotor stimulant effects of ethanol. Psychopharmacology (Berlin) 2001, 155:91-99.
    • (2001) Psychopharmacology (Berlin) , vol.155 , pp. 91-99
    • Lessov, C.N.1    Palmer, A.A.2    Quick, E.A.3    Phillips, T.J.4
  • 56
    • 0034537207 scopus 로고    scopus 로고
    • Repeated ethanol administration induces short- and long-term changes in enkephalin and dynorphin tissue concentrations in rat brain
    • Lindholm S., Ploj K., Franck J., Nylander I. Repeated ethanol administration induces short- and long-term changes in enkephalin and dynorphin tissue concentrations in rat brain. Alcohol 2000, 22:165-171.
    • (2000) Alcohol , vol.22 , pp. 165-171
    • Lindholm, S.1    Ploj, K.2    Franck, J.3    Nylander, I.4
  • 57
    • 46749093301 scopus 로고    scopus 로고
    • Dynorphin is a downstream effector of striatal BDNF regulation of ethanol intake
    • Logrip M.L., Janak P.H., Ron D. Dynorphin is a downstream effector of striatal BDNF regulation of ethanol intake. FASEB Journal 2008, 22:2393-2404.
    • (2008) FASEB Journal , vol.22 , pp. 2393-2404
    • Logrip, M.L.1    Janak, P.H.2    Ron, D.3
  • 63
    • 3342943177 scopus 로고    scopus 로고
    • An in vivo profile of beta-endorphin release in the arcuate nucleus and nucleus accumbens following exposure to stress or alcohol
    • Marinelli P.W., Quirion R., Gianoulakis C. An in vivo profile of beta-endorphin release in the arcuate nucleus and nucleus accumbens following exposure to stress or alcohol. Neuroscience 2004, 127:777-784.
    • (2004) Neuroscience , vol.127 , pp. 777-784
    • Marinelli, P.W.1    Quirion, R.2    Gianoulakis, C.3
  • 64
    • 0032031305 scopus 로고    scopus 로고
    • Neurobiological similarities in depression and drug dependence: a self-medication hypothesis
    • Markou A., Kosten T.R., Koob G.F. Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology 1998, 18:135-174.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 135-174
    • Markou, A.1    Kosten, T.R.2    Koob, G.F.3
  • 65
    • 49849104302 scopus 로고    scopus 로고
    • Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling
    • Mash D.C., French-Mullen J., Adi N., Qin Y., Buck A., Pablo J. Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling. PLoS ONE 2007, 2:e1187.
    • (2007) PLoS ONE , vol.2
    • Mash, D.C.1    French-Mullen, J.2    Adi, N.3    Qin, Y.4    Buck, A.5    Pablo, J.6
  • 66
    • 0032466081 scopus 로고    scopus 로고
    • Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents
    • McBride W.J., Li T.K. Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Critical Reviews in Neurobiology 1998, 12:339-369.
    • (1998) Critical Reviews in Neurobiology , vol.12 , pp. 339-369
    • McBride, W.J.1    Li, T.K.2
  • 67
    • 80052966767 scopus 로고    scopus 로고
    • Ethanol modulation of synaptic plasticity
    • McCool B.A. Ethanol modulation of synaptic plasticity. Neuropharmacology 2011, 61:1097-1108.
    • (2011) Neuropharmacology , vol.61 , pp. 1097-1108
    • McCool, B.A.1
  • 69
    • 0038383854 scopus 로고    scopus 로고
    • Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses
    • McLaughlin J.P., Marton-Popovici M., Chavkin C. Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses. Journal of Neuroscience 2003, 23:5674-5683.
    • (2003) Journal of Neuroscience , vol.23 , pp. 5674-5683
    • McLaughlin, J.P.1    Marton-Popovici, M.2    Chavkin, C.3
  • 70
    • 34548253841 scopus 로고    scopus 로고
    • Effects of matrix metalloproteinase inhibition on short- and long-term plasticity of schaffer collateral/CA1 synapses
    • Meighan P.C., Meighan S.E., Davis C.J., Wright J.W., Harding J.W. Effects of matrix metalloproteinase inhibition on short- and long-term plasticity of schaffer collateral/CA1 synapses. Journal of Neurochemistry 2007, 102:2085-2096.
    • (2007) Journal of Neurochemistry , vol.102 , pp. 2085-2096
    • Meighan, P.C.1    Meighan, S.E.2    Davis, C.J.3    Wright, J.W.4    Harding, J.W.5
  • 71
    • 33645103421 scopus 로고    scopus 로고
    • Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity
    • Meighan S.E., Meighan P.C., Choudhury P., Davis C.J., Olson M.L., Zornes P.A., et al. Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity. Journal of Neurochemistry 2006, 96:1227-1241.
    • (2006) Journal of Neurochemistry , vol.96 , pp. 1227-1241
    • Meighan, S.E.1    Meighan, P.C.2    Choudhury, P.3    Davis, C.J.4    Olson, M.L.5    Zornes, P.A.6
  • 72
    • 26844458361 scopus 로고    scopus 로고
    • A single injection of the kappa opioid antagonist norbinaltorphimine increases ethanol consumption in rats
    • Mitchell J.M., Liang M.T., Fields H.L. A single injection of the kappa opioid antagonist norbinaltorphimine increases ethanol consumption in rats. Psychopharmacology (Berlin) 2005, 182:384-392.
    • (2005) Psychopharmacology (Berlin) , vol.182 , pp. 384-392
    • Mitchell, J.M.1    Liang, M.T.2    Fields, H.L.3
  • 73
    • 33847746740 scopus 로고    scopus 로고
    • Reduction of methamphetamine-induced sensitization and reward in matrix metalloproteinase-2 and -9-deficient mice
    • Mizoguchi H., Yamada K., Niwa M., Mouri A., Mizuno T., Noda Y., et al. Reduction of methamphetamine-induced sensitization and reward in matrix metalloproteinase-2 and -9-deficient mice. Journal of Neurochemistry 2007, 100:1579-1588.
    • (2007) Journal of Neurochemistry , vol.100 , pp. 1579-1588
    • Mizoguchi, H.1    Yamada, K.2    Niwa, M.3    Mouri, A.4    Mizuno, T.5    Noda, Y.6
  • 75
    • 0021876216 scopus 로고
    • Motivational properties of kappa and mu opioid receptor agonists studied with place and taste preference conditioning
    • Mucha R.F., Herz A. Motivational properties of kappa and mu opioid receptor agonists studied with place and taste preference conditioning. Psychopharmacology (Berlin) 1985, 86:274-280.
    • (1985) Psychopharmacology (Berlin) , vol.86 , pp. 274-280
    • Mucha, R.F.1    Herz, A.2
  • 76
    • 35548969254 scopus 로고    scopus 로고
    • The extracellular protease matrix metalloproteinase-9 is activated by inhibitory avoidance learning and required for long-term memory
    • Nagy V., Bozdagi O., Huntley G.W. The extracellular protease matrix metalloproteinase-9 is activated by inhibitory avoidance learning and required for long-term memory. Learning & Memory 2007, 14:655-664.
    • (2007) Learning & Memory , vol.14 , pp. 655-664
    • Nagy, V.1    Bozdagi, O.2    Huntley, G.W.3
  • 77
    • 33644522107 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory
    • Nagy V., Bozdagi O., Matynia A., Balcerzyk M., Okulski P., Dzwonek J., et al. Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory. Journal of Neuroscience 2006, 26:1923-1934.
    • (2006) Journal of Neuroscience , vol.26 , pp. 1923-1934
    • Nagy, V.1    Bozdagi, O.2    Matynia, A.3    Balcerzyk, M.4    Okulski, P.5    Dzwonek, J.6
  • 78
    • 79957848671 scopus 로고    scopus 로고
    • Kappa-opioid receptors are implicated in the increased potency of intra-accumbens nalmefene in ethanol-dependent rats
    • Nealey K.A., Smith A.W., Davis S.M., Smith D.G., Walker B.M. kappa-opioid receptors are implicated in the increased potency of intra-accumbens nalmefene in ethanol-dependent rats. Neuropharmacology 2011, 61:35-42.
    • (2011) Neuropharmacology , vol.61 , pp. 35-42
    • Nealey, K.A.1    Smith, A.W.2    Davis, S.M.3    Smith, D.G.4    Walker, B.M.5
  • 79
    • 0027173626 scopus 로고
    • Cellular responses to chronic treatment with drugs of abuse
    • Nestler E.J. Cellular responses to chronic treatment with drugs of abuse. Critical Reviews in Neurobiology 1993, 7:23-39.
    • (1993) Critical Reviews in Neurobiology , vol.7 , pp. 23-39
    • Nestler, E.J.1
  • 80
    • 33746900423 scopus 로고    scopus 로고
    • The mesolimbic dopamine reward circuit in depression
    • Nestler E.J., Carlezon W.A. The mesolimbic dopamine reward circuit in depression. Biological Psychiatry 2006, 59:1151-1159.
    • (2006) Biological Psychiatry , vol.59 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon, W.A.2
  • 81
    • 0029047081 scopus 로고
    • Brain dynorphin and enkephalin systems in Fischer and Lewis rats: effects of morphine tolerance and withdrawal
    • Nylander I., Vlaskovska M., Terenius L. Brain dynorphin and enkephalin systems in Fischer and Lewis rats: effects of morphine tolerance and withdrawal. Brain Research 1995, 683:25-35.
    • (1995) Brain Research , vol.683 , pp. 25-35
    • Nylander, I.1    Vlaskovska, M.2    Terenius, L.3
  • 84
    • 0029563776 scopus 로고
    • Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system
    • Ortiz J., Fitzgerald L.W., Charlton M., Lane S., Trevisan L., Guitart X., et al. Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system. Synapse 1995, 21:289-298.
    • (1995) Synapse , vol.21 , pp. 289-298
    • Ortiz, J.1    Fitzgerald, L.W.2    Charlton, M.3    Lane, S.4    Trevisan, L.5    Guitart, X.6
  • 85
    • 0022494591 scopus 로고
    • Psychotomimesis mediated by kappa opiate receptors
    • Pfeiffer A., Brantl V., Herz A., Emrich H.M. Psychotomimesis mediated by kappa opiate receptors. Science 1986, 233:774-776.
    • (1986) Science , vol.233 , pp. 774-776
    • Pfeiffer, A.1    Brantl, V.2    Herz, A.3    Emrich, H.M.4
  • 86
    • 0035884949 scopus 로고    scopus 로고
    • Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens
    • Pliakas A.M., Carlson R.R., Neve R.L., Konradi C., Nestler E.J., Carlezon W.A. Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. Journal of Neuroscience 2001, 21:7397-7403.
    • (2001) Journal of Neuroscience , vol.21 , pp. 7397-7403
    • Pliakas, A.M.1    Carlson, R.R.2    Neve, R.L.3    Konradi, C.4    Nestler, E.J.5    Carlezon, W.A.6
  • 87
    • 19244369081 scopus 로고    scopus 로고
    • Ethanol withdrawal enhances the prodynorphin system activity in the rat nucleus accumbens
    • Przewlocka B., Turchan J., Lason W., Przewlocki R. Ethanol withdrawal enhances the prodynorphin system activity in the rat nucleus accumbens. Neuroscience Letters 1997, 238:13-16.
    • (1997) Neuroscience Letters , vol.238 , pp. 13-16
    • Przewlocka, B.1    Turchan, J.2    Lason, W.3    Przewlocki, R.4
  • 88
    • 0029910859 scopus 로고    scopus 로고
    • Intra-amygdala muscimol decreases operant ethanol self-administration in dependent rats
    • Roberts A.J., Cole M., Koob G.F. Intra-amygdala muscimol decreases operant ethanol self-administration in dependent rats. Alcoholism: Clinical and Experimental Research 1996, 20:1289-1298.
    • (1996) Alcoholism: Clinical and Experimental Research , vol.20 , pp. 1289-1298
    • Roberts, A.J.1    Cole, M.2    Koob, G.F.3
  • 89
    • 0034008709 scopus 로고    scopus 로고
    • Excessive ethanol drinking following a history of dependence: animal model of allostasis
    • Roberts A.J., Heyser C.J., Cole M., Griffin P., Koob G.F. Excessive ethanol drinking following a history of dependence: animal model of allostasis. Neuropsychopharmacology 2000, 22:581-594.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 581-594
    • Roberts, A.J.1    Heyser, C.J.2    Cole, M.3    Griffin, P.4    Koob, G.F.5
  • 90
    • 0018583595 scopus 로고
    • Long-term ethanol administration methods for rats: advantages of inhalation over intubation or liquid diets
    • Rogers J., Wiener S.G., Bloom F.E. Long-term ethanol administration methods for rats: advantages of inhalation over intubation or liquid diets. Behavioral and Neural Biology 1979, 27:466-486.
    • (1979) Behavioral and Neural Biology , vol.27 , pp. 466-486
    • Rogers, J.1    Wiener, S.G.2    Bloom, F.E.3
  • 91
    • 0032870007 scopus 로고    scopus 로고
    • Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens
    • Rosin A., Lindholm S., Franck J., Georgieva J. Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens. Neuroscience Letters 1999, 275:1-4.
    • (1999) Neuroscience Letters , vol.275 , pp. 1-4
    • Rosin, A.1    Lindholm, S.2    Franck, J.3    Georgieva, J.4
  • 93
    • 77950370052 scopus 로고    scopus 로고
    • Functional polymorphism of matrix metalloproteinase-9 (MMP-9) gene in alcohol dependence: family and case control study
    • Samochowiec A., Grzywacz A., Kaczmarek L., Bienkowski P., Samochowiec J., Mierzejewski P., et al. Functional polymorphism of matrix metalloproteinase-9 (MMP-9) gene in alcohol dependence: family and case control study. Brain Research 2010, 1327:103-106.
    • (2010) Brain Research , vol.1327 , pp. 103-106
    • Samochowiec, A.1    Grzywacz, A.2    Kaczmarek, L.3    Bienkowski, P.4    Samochowiec, J.5    Mierzejewski, P.6
  • 94
    • 66149171354 scopus 로고    scopus 로고
    • As sharp as Occam?
    • Schattner A. As sharp as Occam?. Lancet 2009, 373:1996.
    • (2009) Lancet , vol.373 , pp. 1996
    • Schattner, A.1
  • 96
    • 0023489245 scopus 로고
    • Motivational properties of opioids: evidence that an activation of delta-receptors mediates reinforcement processes
    • Shippenberg T.S., Bals-Kubik R., Herz A. Motivational properties of opioids: evidence that an activation of delta-receptors mediates reinforcement processes. Brain Research 1987, 436:234-239.
    • (1987) Brain Research , vol.436 , pp. 234-239
    • Shippenberg, T.S.1    Bals-Kubik, R.2    Herz, A.3
  • 97
    • 0022822520 scopus 로고
    • Differential effects of mu and kappa opioid systems on motivational processes
    • Shippenberg T.S., Herz A. Differential effects of mu and kappa opioid systems on motivational processes. NIDA Research Monographs 1986, 75:563-566.
    • (1986) NIDA Research Monographs , vol.75 , pp. 563-566
    • Shippenberg, T.S.1    Herz, A.2
  • 98
    • 4444332549 scopus 로고    scopus 로고
    • Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects
    • Shirayama Y., Ishida H., Iwata M., Hazama G.I., Kawahara R., Duman R.S. Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects. Journal of Neurochemistry 2004, 90:1258-1268.
    • (2004) Journal of Neurochemistry , vol.90 , pp. 1258-1268
    • Shirayama, Y.1    Ishida, H.2    Iwata, M.3    Hazama, G.I.4    Kawahara, R.5    Duman, R.S.6
  • 102
    • 79960843031 scopus 로고    scopus 로고
    • Plasticity associated with escalated operant ethanol self-administration during acute withdrawal in ethanol-dependent rats requires intact matrix metalloproteinase systems
    • Smith A.W., Nealey K.A., Wright J.W., Walker B.M. Plasticity associated with escalated operant ethanol self-administration during acute withdrawal in ethanol-dependent rats requires intact matrix metalloproteinase systems. Neurobiology of Learning and Memory 2011, 96:199-206.
    • (2011) Neurobiology of Learning and Memory , vol.96 , pp. 199-206
    • Smith, A.W.1    Nealey, K.A.2    Wright, J.W.3    Walker, B.M.4
  • 104
    • 0016045280 scopus 로고
    • An opponent-process theory of motivation. I. Temporal dynamics of affect
    • Solomon R.L., Corbit J.D. An opponent-process theory of motivation. I. Temporal dynamics of affect. Psychological Review 1974, 81:119-145.
    • (1974) Psychological Review , vol.81 , pp. 119-145
    • Solomon, R.L.1    Corbit, J.D.2
  • 106
    • 77953288431 scopus 로고    scopus 로고
    • Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration
    • Sperling R.E., Gomes S.M., Sypek E.I., Carey A.N., McLaughlin J.P. Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration. Psychopharmacology (Berlin) 2010, 210:199-209.
    • (2010) Psychopharmacology (Berlin) , vol.210 , pp. 199-209
    • Sperling, R.E.1    Gomes, S.M.2    Sypek, E.I.3    Carey, A.N.4    McLaughlin, J.P.5
  • 107
    • 0031949311 scopus 로고    scopus 로고
    • A comparison of the effects of the opioid antagonists naltrexone, naltrindole, and beta-funaltrexamine on ethanol consumption in the rat
    • Stromberg M.F., Casale M., Volpicelli L., Volpicelli J.R., O'Brien C.P. A comparison of the effects of the opioid antagonists naltrexone, naltrindole, and beta-funaltrexamine on ethanol consumption in the rat. Alcohol 1998, 15:281-289.
    • (1998) Alcohol , vol.15 , pp. 281-289
    • Stromberg, M.F.1    Casale, M.2    Volpicelli, L.3    Volpicelli, J.R.4    O'Brien, C.P.5
  • 108
    • 77957904093 scopus 로고    scopus 로고
    • Office of Applied Studies, DHHS Publication, Rockville, MD, Substance Abuse and Mental Health Services Administration
    • Substance Abuse and Mental Health Services Administration Results from the 2009 national survey on drug use and health 2010, Office of Applied Studies, DHHS Publication, Rockville, MD.
    • (2010) Results from the 2009 national survey on drug use and health
  • 109
    • 0033103771 scopus 로고    scopus 로고
    • Cellular sites for dynorphin activation of kappa-opioid receptors in the rat nucleus accumbens shell
    • Svingos A.L., Colago E.E., Pickel V.M. Cellular sites for dynorphin activation of kappa-opioid receptors in the rat nucleus accumbens shell. Journal of Neuroscience 1999, 19:1804-1813.
    • (1999) Journal of Neuroscience , vol.19 , pp. 1804-1813
    • Svingos, A.L.1    Colago, E.E.2    Pickel, V.M.3
  • 111
    • 0032913423 scopus 로고    scopus 로고
    • The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat
    • Turchan J., Przewlocka B., Toth G., Lason W., Borsodi A., Przewlocki R. The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat. Neuroscience 1999, 91:971-977.
    • (1999) Neuroscience , vol.91 , pp. 971-977
    • Turchan, J.1    Przewlocka, B.2    Toth, G.3    Lason, W.4    Borsodi, A.5    Przewlocki, R.6
  • 112
    • 0036798776 scopus 로고    scopus 로고
    • Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor
    • Valdez G.R., Roberts A.J., Chan K., Davis H., Brennan M., Zorrilla E.P., et al. Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor. Alcoholism: Clinical and Experimental Research 2002, 26:1494-1501.
    • (2002) Alcoholism: Clinical and Experimental Research , vol.26 , pp. 1494-1501
    • Valdez, G.R.1    Roberts, A.J.2    Chan, K.3    Davis, H.4    Brennan, M.5    Zorrilla, E.P.6
  • 113
    • 77956647916 scopus 로고    scopus 로고
    • Effects of prolonged ethanol vapor exposure on forced swim behavior, and neuropeptide Y and corticotropin-releasing factor levels in rat brains
    • Walker B.M., Drimmer D.A., Walker J.L., Liu T., Mathe A.A., Ehlers C.L. Effects of prolonged ethanol vapor exposure on forced swim behavior, and neuropeptide Y and corticotropin-releasing factor levels in rat brains. Alcohol 2010, 44:487-493.
    • (2010) Alcohol , vol.44 , pp. 487-493
    • Walker, B.M.1    Drimmer, D.A.2    Walker, J.L.3    Liu, T.4    Mathe, A.A.5    Ehlers, C.L.6
  • 114
    • 34249683744 scopus 로고    scopus 로고
    • Intracerebroventricular ethanol-induced conditioned place preferences are prevented by fluphenazine infusions into the nucleus accumbens of rats
    • Walker B.M., Ettenberg A. Intracerebroventricular ethanol-induced conditioned place preferences are prevented by fluphenazine infusions into the nucleus accumbens of rats. Behavioral Neuroscience 2007, 121:401-410.
    • (2007) Behavioral Neuroscience , vol.121 , pp. 401-410
    • Walker, B.M.1    Ettenberg, A.2
  • 115
    • 33845906093 scopus 로고    scopus 로고
    • The gamma-aminobutyric acid-B receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats
    • Walker B.M., Koob G.F. The gamma-aminobutyric acid-B receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats. Alcoholism: Clinical and Experimental Research 2007, 31:11-18.
    • (2007) Alcoholism: Clinical and Experimental Research , vol.31 , pp. 11-18
    • Walker, B.M.1    Koob, G.F.2
  • 116
    • 38149072294 scopus 로고    scopus 로고
    • Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence
    • Walker B.M., Koob G.F. Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. Neuropsychopharmacology 2008, 33:643-652.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 643-652
    • Walker, B.M.1    Koob, G.F.2
  • 117
    • 84861188841 scopus 로고    scopus 로고
    • Targeting Dynorphin/Kappa Opioid Receptor Systems to Treat Alcohol Abuse and Dependence
    • in press
    • Walker B.M., Valdez G.R., McLaughlin J.P., Bakalkin G. Targeting Dynorphin/Kappa Opioid Receptor Systems to Treat Alcohol Abuse and Dependence. Alcohol 2012, in press.
    • (2012) Alcohol
    • Walker, B.M.1    Valdez, G.R.2    McLaughlin, J.P.3    Bakalkin, G.4
  • 118
    • 78649910013 scopus 로고    scopus 로고
    • Systemic kappa-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats
    • Walker B.M., Zorrilla E.P., Koob G.F. Systemic kappa-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats. Addiction Biology 2011, 16:116-119.
    • (2011) Addiction Biology , vol.16 , pp. 116-119
    • Walker, B.M.1    Zorrilla, E.P.2    Koob, G.F.3
  • 120
    • 58049150787 scopus 로고    scopus 로고
    • Dissecting motivational circuitry to understand substance abuse
    • Wheeler R.A., Carelli R.M. Dissecting motivational circuitry to understand substance abuse. Neuropharmacology 2009, 56(Suppl 1):149-159.
    • (2009) Neuropharmacology , vol.56 , Issue.SUPPL. 1 , pp. 149-159
    • Wheeler, R.A.1    Carelli, R.M.2
  • 121
    • 69949105896 scopus 로고    scopus 로고
    • Influence of dorsal hippocampal lesions and MMP inhibitors on spontaneous recovery following a habituation/classical conditioning head-shake task
    • Wiediger R.V., Wright J.W. Influence of dorsal hippocampal lesions and MMP inhibitors on spontaneous recovery following a habituation/classical conditioning head-shake task. Neurobiology of Learning and Memory 2009, 92:504-511.
    • (2009) Neurobiology of Learning and Memory , vol.92 , pp. 504-511
    • Wiediger, R.V.1    Wright, J.W.2
  • 122
    • 84865128037 scopus 로고    scopus 로고
    • The effect of intermittent alcohol vapor or pulsatile heroin on somatic and negative affective indices during spontaneous withdrawal in wistar rats
    • in press
    • Williams A.M., Reis D.J., Powell A.S., Neira L.J., Nealey K.A., Ziegler C.E. The effect of intermittent alcohol vapor or pulsatile heroin on somatic and negative affective indices during spontaneous withdrawal in wistar rats. Psychopharmacology 2012, in press.
    • (2012) Psychopharmacology
    • Williams, A.M.1    Reis, D.J.2    Powell, A.S.3    Neira, L.J.4    Nealey, K.A.5    Ziegler, C.E.6
  • 123
    • 0031762121 scopus 로고    scopus 로고
    • Oral ethanol-reinforced responding in rhesus monkeys: effects of opioid antagonists selective for the mu-, kappa-, or delta-receptor
    • Williams K.L., Woods J.H. Oral ethanol-reinforced responding in rhesus monkeys: effects of opioid antagonists selective for the mu-, kappa-, or delta-receptor. Alcoholism: Clinical and Experimental Research 1998, 22:1634-1639.
    • (1998) Alcoholism: Clinical and Experimental Research , vol.22 , pp. 1634-1639
    • Williams, K.L.1    Woods, J.H.2
  • 124
    • 34548801908 scopus 로고    scopus 로고
    • Inhibition of hippocampal matrix metalloproteinase-3 and -9 disrupts spatial memory
    • Wright J.W., Brown T.E., Harding J.W. Inhibition of hippocampal matrix metalloproteinase-3 and -9 disrupts spatial memory. Neural Plasticity 2007, 2007:73813.
    • (2007) Neural Plasticity , vol.2007 , pp. 73813
    • Wright, J.W.1    Brown, T.E.2    Harding, J.W.3
  • 125
    • 2342655011 scopus 로고    scopus 로고
    • The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory
    • Wright J.W., Harding J.W. The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory. Progress in Neurobiology 2004, 72:263-293.
    • (2004) Progress in Neurobiology , vol.72 , pp. 263-293
    • Wright, J.W.1    Harding, J.W.2
  • 126
    • 77951642306 scopus 로고    scopus 로고
    • Contributions of matrix metalloproteinases to neural plasticity, habituation, associative learning and drug addiction
    • Wright J.W., Harding J.W. Contributions of matrix metalloproteinases to neural plasticity, habituation, associative learning and drug addiction. Neural Plasticity 2009, 2009:579382.
    • (2009) Neural Plasticity , vol.2009 , pp. 579382
    • Wright, J.W.1    Harding, J.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.