Enhanced sensitivity of pituitary β-endorphin to ethanol in subjects at high risk of alcoholism

Archives of General Psychiatry

Volumn 53, Issue 3, 1996, Pages 250-257

  Gianoulakis, Christina ^a   Krishnan, Brinda ^a   Thavundayil, Joseph ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BETA ENDORPHIN; HYDROCORTISONE;

ADRENAL CORTEX; ADULT; ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOLISM; ARTICLE; CLINICAL ARTICLE; DOSE RESPONSE; FEMALE; HIGH RISK POPULATION; HUMAN; HYDROCORTISONE BLOOD LEVEL; MALE; RISK ASSESSMENT; SEX DIFFERENCE;

EID: 0029983167     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.1996.01830030072011     Document Type: Article

References (62)

1. Cloninger CR, Bohman M, Sigvardsson S, Von Knorring AL. Psychopathology in adopted-out children of alcoholics: the Stockholm adoption study In: Galanter M, ed. Recent Developments in Alcoholism New York, NY Plenum Press; 1985:37-51.
2. Goldman D, Linnoila M. Genetic approaches to alcoholism. Prog Neuropsychopharmacol Biol Psychiatry. 1986;10:237-242
3. Eriksson K. Rusi M Finnish selection studies on alcohol-related behaviors: general outline In: McClearn GE, Deitrich RA, Erwin G, eds. Development of Animal Models as Pharmacogenetic Tools. Boulder, Colo; 1978:87-117. National Institute of Alcohol Abuse and Alcoholism Research Monograph 6.
4. Keane B, Leonard BE. Rodent models of alcoholism: a review Alcohol Alcohol. 1989,24:299-309.
5. Hughes J, Smith TW, Kosterlitz HW, Fathergill LA, Morgan BA, Morris HR. Identification of two related pentapeptides from the brain with potent opiate agonist activity. Nature. 1975;258.577-579
6. Bradbury AF, Smyth DG, Snell CR, Birdsall NJM, Hulme EC. C-fragment of lipotropin has a high affinity for brain opiate receptors Nature. 1976;260:793.
7. Goldstein A, Tachibana S, Lowney LI, Hold L. Dynorphin (1-13): an extraordinarily potent opioid peptide. Proc Natl Acad Sci USA. 1979;76:6666-6670
8. Olson GA, Olson RD, Kastin AB. Endogenous opiates: 1989 review Peptides. 1990,11:1277-1304.
9. Khachaturian H, Lewis ME, Schafer MKH, Watson SJ. Anatomy of the CNS opioid systems Trends Neurosci. 1985,10.111-119.
10. Van Ree JM, De Wied D, Bradbury AF, Hulme EC, Smyth DG, Snell CR. induction of tolerance to the analgesic action of lipotropin C-fragment Nature. 1976,64 792-794.
11. Spanagel R, Herz A, Shippenberg T. Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci USA 1991,89:2046-2050.
12. De Waele JP, Papachristou DN, Gianoulakis C The alcohol-preferring C57BL/6 mice present an enhanced sensitivity of the hypothalamic β-endorphin system to ethanol than the alcohol-avoiding DBA/2 mice. J Pharmacol Exp Ther. 1992; 261.788-794.
13. Keith LD, Crabbe JC, Robertson LM, Kendall JW. Ethanol-stimulated endorphin and corticotropin secretion in vitro Brain Res. 1986,367:222-229.
14. De Waele JP, Gianoulakis C. Effects of single and repeated exposures to ethanol on the hypothalamic β-endorphin and CRH release by the C57BL/6 and DBA/2 strains of mice. Neuroendocrinology. 1993;57:700-709.
15. Naber O, Sohle MG, Pickar D. Ethanol increases opioid activity in plasma of normal volunteers. Pharmacopsychiatry. 1981;14:160-161
16. Gianoulakis C, Beliveau D, Angelogianni P, Meaney M, Thavundayil J, Tawar V, Dumas M Different pituitary β-endorphin and adrenal cortisol response to ethanol in individuals with high and low risk for future development of alcoholism Life Sci. 1989;45.1097-1109
17. Valimaki MK, Harkonen M, Eriksson CJP, Ylikahn RH Sex hormone and adrenocortical steroids in men acutely intoxicated with ethanol. Alcohol. 1984; 1.89-93.
18. Mendelson JH, Stein S. Serum cortisol levels in alcoholic and non-alcoholic subjects during experimentally induced ethanol intoxication. Psychosom Med 1966,28:616-626
19. Tabakoff B, Jaffe R, Ritzmann R Corticosterone concentrations in mice during ethanol drinking and withdrawal J Pharm Pharmacol. 1978;30 371-374.
20. Mendelson JH, Ogata M, Mello NK Adrenal function and alcoholism, I: serum cortisol. Psychosom Med 1971,33:145-157.
21. Seto A, Triconi S. Goodwin DW, Kolodney R, Sullivan T. Biochemical correlates of ethanol-induced flushing in Orientals. J Stud Alcohol. 1978,39:1-11.
22. Schuckit MA, Gold E, Risch C. Plasma cortisol levels following ethanol in sons of alcoholics and controls Arch Gen Psychiatry. 1987,44 942-945.
23. Jenkins JS, Conolly J Adrenocortical response to ethanol in man. BMJ. 1968, 2:804-805.
24. Merry J, Marks V. Plasma-hydrocortisone response to ethanol in chronic alcoholics Lancet. 1969;1 921-923
25. Schuckit MA. Differences in plasma cortisol after injection of ethanol in relatives of alcoholics and controls. J Clin Psychiatry. 1984;45:374-376.
26. Schuckit MA, Risch SC, Gold EO. Alcohol consumption, ACTH level, and family history of alcoholism. Am J Psychiatry. 1988,145:1391-1395
27. Rivier C, Bruhn T, Vale W Effect of ethanol on the hypothalamic-pituitary axis in the rat: role of corticotropin-releasing factor J Pharmacol Exp Ther. 1984; 229:127-131
28. Gambert SR, Pontzer CH, Barboriak JJ. Effect of ethanol consumption on central nervous system (CNS) β-endorphin and ACTH. Horm Metab Res. 1981; 13.242-243
29. Noble EP, Kakihana R, Butte JC Corticosterone metabolism in alcoholadapted mice. In: Roach MK, Mclssac WM, Creaven PJ, eds. Biological Aspects ot Alcohol. Austin, Tex. The University of Texas Press, 1971:389
30. Leppaluoto J, Rapeli M, Varis R, Ranta T. Secretion of anterior pituitary hormones in man: effects of ethyl alcohol. Acta Physiol Scand. 1975,95 400-406.
31. Guillemin R, Vargo T, Rossier J, Minick S, Ling N, Rivier C, Vale W, Bloom F β-endorphin and adrenocorticotropin are secreted concomitantly by the pituitary gland. Science. 1977;197:1367-1369.
32. Gianoulakis C. Characterization of the effects of short-term ethanol administration on the release of β-endorphin peptides by the rat hypothalamus. Eur J Pharmacol 1990;180:21-29.
33. Selzer ML. The Michigan Alcoholism Screening Test the quest for a new diagnostic instrument. Am J Psychiatry 1971;127 1653-1658
34. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition. Washington, DC: American Psychiatric Association, 1987
35. Endicott J, Andreasen N, Spitzer RL Family History Research Diagnostic Criteria. New York, NY; New York State Psychiatric Institute. 1975.
36. Angelogianni P, Gianoulakis C. Prenatal exposure to ethanol alters the ontogeny of the β-endorphin response to stress. Alcohol Clin Exp Res. 1989;13. 564-571.
37. Weinberg J. Nelson LR, Taylor AN. Hormonal effects of fetal alcohol exposure. In: West JR. ed. Alcohol and Brain Development New York, NY: Oxford University Press; 1986:310-342.
38. Taylor AN, Branch BJ, Nelson LR, Lane LA, Poland RE. Prenatal ethanol and ontogeny of pituitary-adrenal responses to ethanol and morphine. Alcohol. 1986; 3:255-259.
39. Kendler KS, Neale MC, Heath AC, Kessler RC, Eaves LJ. A twin-family study of alcoholism in women. Am J Psychiatry. 1994;151:707-715.
40. Cahalan D, Cisin H. American drinking practices summary from a national probability sample. J Stud Alcohol. 1968;29:130
41. Hawkins RD, Kalant H, Khana JM. Effects of chronic intake of ethanol on rate of ethanol metabolism. Can J Physiol Pharmacol. 1966,44:241-257.
42. Gianoulakis C, Chan JCD, Kalant H, Chretien M Chronic ethanol treatment alters the biosynthesis of β-endorphin by the rat intermediate lobe Can J Physiol Pharmacol. 1983;61 967-976.
43. Bennett HPJ, Browne CA, Solomon S. Purification of the two major forms of rat pituitary corticotropin using only reverse phase liquid chromatography. Biochemistry. 1981;20 4530-4538.
44. Krey L, Lu K, Butler W, Hotchkis J, Piva F, Knoble E Surgical disconnections of the medial basal hypothalamus and pituitary function in the rhesus monkey, II: GH and Cortisol secretion Endocrinology 1975;96:1088-1093
45. Bradbury MJ, Cascio CS, Scribner KA. Dallman MF. Stress-induced adrenocorticotropin secretion: diurnal responses and decreases during stress in the evening are not dependent on corticosterone Endocrinology 1991;128:680-688.
46. Waltman C, McCaul BE, Svlkis D, Boyed G, Wand GS. 0CRH-stimulated ACTH release is blunted in sons of alcoholic fathers. Alcohol Clin Exp Res. 1993,17 443 Abstract
47. Banks WA, Kastin AJ. Minireview. saturable transport of peptides across the blood-brain barrier Life Sci. 1987,41:1319-1338.
48. Banks WA, Kastin AJ Editorial review peptide transport systems for opiates across the blood-brain barrier. Am J Physiol 1990;259:E1-E10.
49. Banks WA. Kastin AJ, Barrera CM. Delivering peptides to the central nervous systems dilemmas and strategies. Pharm Res. 1991;8:1345-1350.
50. Bergland RM, Page RB. Pituitary-brain vascular relations, a new paradigm Science 1979,204:18-24.
51. Banks WA, Kastin AJ The potential for alcohol to affect the passage of peptide and protein hormones across the blood-brain barrier, a hypothesis for a disturbance in brain-body communication In: Zakharis S, ed. Alcohol and the Endocrine System Bethesda, Md; National Institute of Alcohol Abuse and Alcoholism. 1993. NIH publication 93-3533. Research Monograph 23.
52. Volpicelli JR, O'Brien CP, Alterman AI, Hayashida M. Naltrexone and the treatment of alcohol dependence: initial observations. In: Reid LD, ed Opioids, Bulimia and Alcohol Abuse & Alcoholism. New York, NY: Springer-Verlag; 1990: 195-214.
53. Altshuler HL, Philips PE, Feinhandler DE Alteration of ethanol self-administration by naltrexone. Life Sci. 1980;26:679-688.
54. Reid LD, Hunter GA. Morphine and naloxone modulate intake of ethanol. Alcohol 1984; 1:33-37
55. Hubbell CL, Czirr SA, Hunter GA, Beaman CM, LeCann NC, Reid LD. Consumption of ethanol solution is potentiated by morphine and attenuated by naloxone persistently across repeated daily administrations Alcohol 1986,3: 39-54
56. Kornet M, Goosen C, Van Ree JM. Effect of naltrexone on alcohol drinking and after a period of imposed abstinence in free-choice drinking rhesus monkeys. Psychopharmacology. 1991;104:367-376.
57. Froehlich JC, Harts J, Lumeng L, Li T-K Naloxone attenuates voluntary ethanol intake in rats selectively bred for high ethanol preference. Pharmacol Biochem Behav. 1990,35:385-390
58. Froehlich JC, Zweifel M, Hart J, Lumeng L, Li T-K. Importance of delta opioid receptors in maintaining high alcohol drinking. Psychopharmacology. 1991; 103:467-472.
59. Volpicelli JR, Alterman AI, Hayashida M, O'Brien CP Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry. 1992;49:876-880.
60. O'Malley SS, Jaffe AJ, Chang G, Schottenfeld RS, Meyer RE, Rounsaville B Naltrexone and coping skids therapy for alcohol dependence: a controlled study. Arch Gen Psychiatry 1992,49:881-887.
61. Zumoff B, Fukushima DK, Weitzman ED, Kream J, Hellman L. The sex difference in plasma Cortisol concentration in man J Clin Endocrinol Metao. 1974; 39:805-808.
62. Schoneshofer M, Harendt H, Vescei P Simultaneous radioimmunoassay for corticosterone and deoxycortisol in human serum: sex differences in the mean serum concentrations J Clin Chem Clin Biochem 1977;15:69-75