An Extract of Green Tea, Epigallocatechin-3-Gallate, Reduces Periapical Lesions by Inhibiting Cysteine-rich 61 Expression in Osteoblasts

Journal of Endodontics

Volumn 35, Issue 2, 2009, Pages 206-211

  Lee, Yuan Ling ^a,b   Hong, Chi Yuan ^a,b   Kok, Sang Heng ^a,b   Hou, Kuo Liang ^a   Lin, Yi Ting ^b   Chen, Mu Hsiung ^b   Wang, Chih Chiang ^a   Lin, Sze Kwan ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Cyr61; EGCG; human osteoblastic cells; periapical lesion

Indexed keywords

ANTIOXIDANT; CATECHIN; CYSTEINE RICH PROTEIN 61; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; MONOCYTE CHEMOTACTIC PROTEIN 1; ONCOSTATIN M; PLANT EXTRACT;

ANIMAL; ARTICLE; BIOSYNTHESIS; CHEMISTRY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; METABOLISM; NEUTROPHIL CHEMOTAXIS; OSTEOBLAST; OSTEOLYSIS; RAT; TEA; TOOTH PERIAPICAL DISEASE; TUMOR CELL LINE; WISTAR RAT;

ALVEOLAR BONE LOSS; ANIMALS; ANTIOXIDANTS; CATECHIN; CELL LINE, TUMOR; CHEMOKINE CCL2; CHEMOTAXIS, LEUKOCYTE; CYSTEINE-RICH PROTEIN 61; DISEASE MODELS, ANIMAL; HUMANS; ONCOSTATIN M; OSTEOBLASTS; PERIAPICAL PERIODONTITIS; PLANT EXTRACTS; RATS; RATS, WISTAR; TEA;

EID: 58249116962     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2008.11.015     Document Type: Article

References (25)

1. Balentine D.A., Wiseman S.A., and Bouwens L.C. The chemistry of tea flavonoids. Crit Rev Food Sci Nutr 37 (1997) 693-704
2. Chung J.Y., Park J.O., Phyu H., Dong Z., and Yang C.S. Mechanisms of inhibition of the Ras-MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3′-digallate. Faseb J 15 (2001) 2022-2024
3. Pianetti S., Guo S., Kavanagh K.T., and Sonenshein G.E. Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells. Cancer Res 62 (2002) 652-655
4. Chung J.H., Han J.H., Hwang E.J., et al. Dual mechanisms of green tea extract (EGCG)-induced cell survival in human epidermal keratinocytes. Faseb J 17 (2003) 1913-1915
5. Wang C.Y., Tani-Ishii N., and Stashenko P. Bone-resorptive cytokine gene expression in periapical lesions in the rat. Oral Microbiol Immunol 12 (1997) 65-71
6. Lin S.-K., Kok S.-H., Kuo M.Y.-P., et al. Sequential expressions of MMP-1, TIMP-1, IL-6, and COX-2 genes in induced periapical lesions in rats. Eur J Oral Sci 110 (2002) 246-253
7. Moonga B.S., Adebanjo O.A., Wang H.J., et al. Differential effects of interleukin-6 receptor activation on intracellular signaling and bone resorption by isolated rat osteoclasts. J Endocrinol 173 (2002) 395-405
8. Palmqvist P., Persson E., Conaway H.H., and Lerner U.H. IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae. J Immunol 169 (2002) 3353-3362
9. Lin S.K., Kok S.H., Yeh F.T., et al. MEK/ERK and signal transducer and activator of transcription signaling pathways modulate oncostatin M-stimulated CCL2 expression in human osteoblasts through a common transcription factor. Arthritis Rheum 50 (2004) 785-793
10. Brigstock D.R. The CCN family: a new stimulus package. J Endocrinol 178 (2003) 169-175
11. Lau L.F., and Lam S.C. The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res 248 (1999) 44-57
12. Koch A., and Distler O. Vasculopathy and disordered angiogenesis in selected rheumatic diseases: rheumatoid arthritis and systemic sclerosis. Arthritis Res Ther 9 (2007) S3
13. Kojima-Yuasa A., Hua J.J., Kennedy D.O., and Matsui-Yuasa I. Green tea extract inhibits angiogenesis of human umbilical vein endothelial cells through reduction of expression of VEGF receptors. Life Sci 73 (2003) 1299-1313
14. Lin S.-K., Chang H.-H., Chen Y.-J., et al. EGCG diminishes CCL2 expression in human osteoblastic cell via up-regulating PI3K/Akt/Raf-1 interaction: a potential therapeutic benefit for arthritis. Arthritis Rheum 58 (2008) 3145-3156
15. Lin S.K., Kok S.H., Shun C.T., et al. Tumor necrosis factor-alpha stimulates the expression of C-C chemokine ligand 2 gene in fibroblasts from the human nasal polyp through the pathways of mitogen-activated protein kinase. Am J Rhinol 21 (2007) 251-255
16. Lin S.K., Kok S.H., Kuo M.Y., et al. Nitric oxide promotes infectious bone resorption by enhancing cytokine-stimulated interstitial collagenase synthesis in osteoblasts. J Bone Miner Res 18 (2003) 39-46
17. Lin S.K., Kok S.H., Lin L.D., et al. Nitric oxide promotes the progression of periapical lesion via inducing macrophage and osteoblast apoptosis. Oral Microbiol Immunol 22 (2007) 24-29
18. Kao Y.-H., Hiipakka R.A., and Liao S. Modulation of endocrine systems and food intake by green tea epigallocatechin gallate. Endocrinology 141 (2000) 980-987
19. Lin S.K., Hong C.Y., Chang H.H., et al. Immunolocalization of macrophages and transforming growth factor-beta 1 in induced rat periapical lesions. J Endod 26 (2000) 335-340
20. Chen C.-C., Mo F.-E., and Lau L.F. The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts. J Biol Chem 276 (2001) 47329-47337
21. Schober J.M., Chen N., Grzeszkiewicz T.M., et al. Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions. Blood 99 (2002) 4457-4465
22. Lin B.-R., Chang C.-C., Chen L.-R., et al. Cysteine-rich 61 (CCN1) enhances chemotactic migration, transendothelial cell migration, and intravasation by concomitantly up-regulating chemokine receptor 1 and 2. Mol Cancer Res 5 (2007) 1111-1123
23. Jay P.R., Centrella M., Lorenzo J., Bruce A.G., and Horowitz M.C. Oncostatin-M: a new bone active cytokine that activates osteoblasts and inhibits bone resorption. Endocrinology 137 (1996) 1151-1158
24. Yun J.H., Kim C.S., Cho K.S., Chai J.K., Kim C.K., and Choi S.H. (-)-Epigallocatechin gallate induces apoptosis, via caspase activation, in osteoclasts differentiated from RAW 264.7 cells. J Periodontal Res 42 (2007) 212-218
25. Yun J.-H., Pang E.-K., Kim C.-S., et al. Inhibitory effects of green tea polyphenol (-)-epigallocatechin gallate on the expression of matrix metalloproteinase-9 and on the formation of osteoclasts. J Periodontal Res 39 (2004) 300-307