Simvastatin inhibits cytokine-stimulated Cyr61 expression in osteoblastic cells a therapeutic benefit for arthritis

Arthritis and Rheumatism

Volumn 63, Issue 4, 2011, Pages 1010-1020

  Kok, Sang Heng ^a   Hou, Kuo Liang ^b   Hong, Chi Yuan ^b   Wang, Juo Song ^a   Liang, Po Chin ^a   Chang, Cheng Chi ^b   Hsiao, Michael ^c   Yang, Hsiang ^a   Hsiang Hua Lai, Eddie ^a   Lin, Sze Kwan ^a,b  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c ACADEMIA SINICA   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYSTEINE RICH PROTEIN 61; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LUCIFERASE; MONOCYTE CHEMOTACTIC PROTEIN 1; ONCOSTATIN M; SERINE; SHORT HAIRPIN RNA; SIMVASTATIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CELL INFILTRATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE COURSE; DNA BINDING; DRUG INHIBITION; ELECTROPHORETIC MOBILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EVALUATION; GENE ACTIVITY; GENE DELETION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MUTAGENESIS; NONHUMAN; NORTHERN BLOTTING; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING;

ANIMALS; ANTICHOLESTEREMIC AGENTS; ARTHRITIS, EXPERIMENTAL; CELL LINE, TUMOR; CELLS, CULTURED; CHEMOKINE CCL2; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYSTEINE-RICH PROTEIN 61; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HUMANS; INJECTIONS, INTRA-ARTICULAR; MALE; OSTEOBLASTS; RATS; RATS, SPRAGUE-DAWLEY; SIMVASTATIN; TREATMENT OUTCOME;

EID: 79953710552     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27433     Document Type: Article

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