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Volumn 1, Issue 1, 2011, Pages 16-20

P2X7 receptor as a double-edged sword: Neurotrophic and neurotoxic effects

Author keywords

ATP; Endoplasmic reticulum; Excitotoxicity; Mitochondria; Neuron; P2X7 receptor; Proliferation

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; PURINERGIC P2X7 RECEPTOR;

EID: 84861192792     PISSN: 22118020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomed.2011.10.003     Document Type: Review
Times cited : (8)

References (45)
  • 1
    • 0027264923 scopus 로고
    • ATP - a fast neurotransmitter
    • Edwards F.A., Gibb A.J. ATP - a fast neurotransmitter. FEBS Lett 1993, 325:86-89.
    • (1993) FEBS Lett , vol.325 , pp. 86-89
    • Edwards, F.A.1    Gibb, A.J.2
  • 2
    • 0029560273 scopus 로고
    • Noradrenaline and ATP: cotransmitters and neuromodulators
    • Burnstock G. Noradrenaline and ATP: cotransmitters and neuromodulators. J Physiol Pharmacol 1995, 46:365-384.
    • (1995) J Physiol Pharmacol , vol.46 , pp. 365-384
    • Burnstock, G.1
  • 3
    • 38349101862 scopus 로고    scopus 로고
    • ATP and acetylcholine, equal brethren
    • Zimmermann H. ATP and acetylcholine, equal brethren. Neurochem Int 2008, 52:634-648.
    • (2008) Neurochem Int , vol.52 , pp. 634-648
    • Zimmermann, H.1
  • 4
    • 34248576759 scopus 로고    scopus 로고
    • Physiology and pathophysiology of purinergic neurotransmission
    • Burnstock G. Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev 2007, 87:659-797.
    • (2007) Physiol Rev , vol.87 , pp. 659-797
    • Burnstock, G.1
  • 5
    • 76149099290 scopus 로고    scopus 로고
    • The P2X7 purinergic receptor: from physiology to neurological disorders
    • Skaper SD, Debetto P, Giusti P. The P2X7 purinergic receptor: from physiology to neurological disorders. FASEB J;24:337-345.
    • FASEB J. , vol.24 , pp. 337-345
    • Skaper, S.D.1    Debetto, P.2    Giusti, P.3
  • 7
    • 58049127392 scopus 로고    scopus 로고
    • ATP-gated P2X cation-channels
    • Jarvis M.F., Khakh B.S. ATP-gated P2X cation-channels. Neuropharmacology 2009, 56:208-215.
    • (2009) Neuropharmacology , vol.56 , pp. 208-215
    • Jarvis, M.F.1    Khakh, B.S.2
  • 8
    • 77955848047 scopus 로고    scopus 로고
    • Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo
    • Hu H., Lu W., Zhang M., Zhang X., Argall A.J., Patel S., et al. Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo. Exp Eye Res 2010, 91:425-432.
    • (2010) Exp Eye Res , vol.91 , pp. 425-432
    • Hu, H.1    Lu, W.2    Zhang, M.3    Zhang, X.4    Argall, A.J.5    Patel, S.6
  • 10
    • 0036893424 scopus 로고    scopus 로고
    • Extracellular ATP and nerve growth factor intensify hypoglycemia-induced cell death in primary neurons: role of P2 and NGFRp75 receptors
    • Cavaliere F., Sancesario G., Bernardi G., Volonte C. Extracellular ATP and nerve growth factor intensify hypoglycemia-induced cell death in primary neurons: role of P2 and NGFRp75 receptors. J Neurochem 2002, 83:1129-1138.
    • (2002) J Neurochem , vol.83 , pp. 1129-1138
    • Cavaliere, F.1    Sancesario, G.2    Bernardi, G.3    Volonte, C.4
  • 11
    • 38049110607 scopus 로고    scopus 로고
    • Extracellular ATP mediates necrotic cell swelling in SN4741 dopaminergic neurons through P2X7 receptors
    • Jun D.J., Kim J., Jung S.Y., Song R., Noh J.H., Park Y.S., et al. Extracellular ATP mediates necrotic cell swelling in SN4741 dopaminergic neurons through P2X7 receptors. J Biol Chem 2007, 282:37350-37358.
    • (2007) J Biol Chem , vol.282 , pp. 37350-37358
    • Jun, D.J.1    Kim, J.2    Jung, S.Y.3    Song, R.4    Noh, J.H.5    Park, Y.S.6
  • 12
    • 4043079197 scopus 로고    scopus 로고
    • P2X7 receptor inhibition improves recovery after spinal cord injury
    • Wang X., Arcuino G., Takano T., Lin J., Peng W.G., Wan P., et al. P2X7 receptor inhibition improves recovery after spinal cord injury. Nat Med 2004, 10:821-827.
    • (2004) Nat Med , vol.10 , pp. 821-827
    • Wang, X.1    Arcuino, G.2    Takano, T.3    Lin, J.4    Peng, W.G.5    Wan, P.6
  • 13
    • 68149157440 scopus 로고    scopus 로고
    • Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury
    • Peng W., Cotrina M.L., Han X., Yu H., Bekar L., Blum L., et al. Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury. Proc Natl Acad Sci U S A 2009, 106:12489-12493.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12489-12493
    • Peng, W.1    Cotrina, M.L.2    Han, X.3    Yu, H.4    Bekar, L.5    Blum, L.6
  • 14
    • 64149091916 scopus 로고    scopus 로고
    • Neural progenitor cell death is induced by extracellular ATP via ligation of P2X7 receptor
    • Delarasse C., Gonnord P., Galante M., Auger R., Danile H., Motta I., et al. Neural progenitor cell death is induced by extracellular ATP via ligation of P2X7 receptor. J Neurochem 2009, 109:846-857.
    • (2009) J Neurochem , vol.109 , pp. 846-857
    • Delarasse, C.1    Gonnord, P.2    Galante, M.3    Auger, R.4    Danile, H.5    Motta, I.6
  • 15
    • 21644478216 scopus 로고    scopus 로고
    • Neuronal death induced by endogenous extracellular ATP in retinal cholinergic neuron density control
    • Resta V., Novelli E., Di Virgilio F., Galli-Resta L. Neuronal death induced by endogenous extracellular ATP in retinal cholinergic neuron density control. Development 2005, 132:2873-2882.
    • (2005) Development , vol.132 , pp. 2873-2882
    • Resta, V.1    Novelli, E.2    Di Virgilio, F.3    Galli-Resta, L.4
  • 17
    • 34548398189 scopus 로고    scopus 로고
    • P2X(7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes and ameliorates experimental autoimmune encephalomyelitis
    • Matute C., Torre I., Pérez-Cerdá F., Pérez-Samartín A., Alberdi E., Etxebarria E., et al. P2X(7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes and ameliorates experimental autoimmune encephalomyelitis. J Neurosci 2007, 27:9525-9533.
    • (2007) J Neurosci , vol.27 , pp. 9525-9533
    • Matute, C.1    Torre, I.2    Pérez-Cerdá, F.3    Pérez-Samartín, A.4    Alberdi, E.5    Etxebarria, E.6
  • 20
    • 28844497440 scopus 로고    scopus 로고
    • Supersensitivity of P2X receptors in cerebrocortical cell cultures after in vitro ischemia
    • Wirkner K., Kofalvi A., Fischer W., Günther A., Franke H., Gröger-Arndt H., et al. Supersensitivity of P2X receptors in cerebrocortical cell cultures after in vitro ischemia. J Neurochem 2005, 95:1421-1437.
    • (2005) J Neurochem , vol.95 , pp. 1421-1437
    • Wirkner, K.1    Kofalvi, A.2    Fischer, W.3    Günther, A.4    Franke, H.5    Gröger-Arndt, H.6
  • 21
    • 77949654869 scopus 로고    scopus 로고
    • Inhibition of neuronal cell death after retinoic acid-induced down-regulation of P2X7 nucleotide receptor expression
    • Orellano E.A., Rivera O.J., Chevres M., Chorna N.E., Gonzalez F.A. Inhibition of neuronal cell death after retinoic acid-induced down-regulation of P2X7 nucleotide receptor expression. Mol Cell Biochem 2010, 337:83-99.
    • (2010) Mol Cell Biochem , vol.337 , pp. 83-99
    • Orellano, E.A.1    Rivera, O.J.2    Chevres, M.3    Chorna, N.E.4    Gonzalez, F.A.5
  • 23
    • 77955087130 scopus 로고    scopus 로고
    • Roles of P2X7 receptor in glial and neuroblastoma cells: the therapeutic potential of P2X7 receptor antagonists
    • Sun SH. Roles of P2X7 receptor in glial and neuroblastoma cells: the therapeutic potential of P2X7 receptor antagonists. Mol Neurobiol;41:351-355.
    • Mol Neurobiol. , vol.41 , pp. 351-355
    • Sun, S.H.1
  • 25
  • 26
    • 33846565429 scopus 로고    scopus 로고
    • Ca2+ signals and neuronal death in brain ischemia
    • Bano D., Nicotera P. Ca2+ signals and neuronal death in brain ischemia. Stroke 2007, 38:674-676.
    • (2007) Stroke , vol.38 , pp. 674-676
    • Bano, D.1    Nicotera, P.2
  • 28
    • 67349159879 scopus 로고    scopus 로고
    • Inositol trisphosphate and calcium signalling mechanisms
    • Berridge M.J. Inositol trisphosphate and calcium signalling mechanisms. Biochim Biophys Acta 2009, 1793:933-940.
    • (2009) Biochim Biophys Acta , vol.1793 , pp. 933-940
    • Berridge, M.J.1
  • 29
    • 61349085391 scopus 로고    scopus 로고
    • STIM and Orai: the long-awaited constituents of store-operated calcium entry
    • Varnai P., Hunyady L., Balla T. STIM and Orai: the long-awaited constituents of store-operated calcium entry. Trends Pharmacol Sci 2009, 30:118-128.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 118-128
    • Varnai, P.1    Hunyady, L.2    Balla, T.3
  • 30
    • 1942485783 scopus 로고    scopus 로고
    • Multiplicity of Ca2+ messengers and Ca2+ stores: a perspective from cyclic ADP-ribose and NAADP
    • Lee H.C. Multiplicity of Ca2+ messengers and Ca2+ stores: a perspective from cyclic ADP-ribose and NAADP. Curr Mol Med 2004, 4:227-237.
    • (2004) Curr Mol Med , vol.4 , pp. 227-237
    • Lee, H.C.1
  • 31
    • 0036895383 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the development of diabetes: a review
    • Harding H.P., Ron D. Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes 2002, 51(Suppl. 3):S455-S461.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 3
    • Harding, H.P.1    Ron, D.2
  • 33
    • 33846577831 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain
    • Sokka A.L., Putkonen N., Mudo G., Pryazhnikov E., Reijonen S., Khiroug L., et al. Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain. J Neurosci 2007, 27:901-908.
    • (2007) J Neurosci , vol.27 , pp. 901-908
    • Sokka, A.L.1    Putkonen, N.2    Mudo, G.3    Pryazhnikov, E.4    Reijonen, S.5    Khiroug, L.6
  • 35
    • 42449160489 scopus 로고    scopus 로고
    • NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner
    • Concannon C.G., Ward M.W., Bonner H.P., Kuroki K., Tuffy L.P., Bonner C.T., et al. NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner. J Neurochem 2008, 105:891-903.
    • (2008) J Neurochem , vol.105 , pp. 891-903
    • Concannon, C.G.1    Ward, M.W.2    Bonner, H.P.3    Kuroki, K.4    Tuffy, L.P.5    Bonner, C.T.6
  • 36
    • 68649116755 scopus 로고    scopus 로고
    • SR/ER-mitochondrial local communication: calcium and ROS
    • Csordas G., Hajnoczky G. SR/ER-mitochondrial local communication: calcium and ROS. Biochim Biophys Acta 2009, 1787:1352-1362.
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 1352-1362
    • Csordas, G.1    Hajnoczky, G.2
  • 37
    • 0033584858 scopus 로고    scopus 로고
    • Increased proliferation rate of lymphoid cells transfected with the P2X(7) ATP receptor
    • Baricordi O.R., Melchiorri L., Adinolfi E., Falzoni S., Chiozzi P., Buell G., et al. Increased proliferation rate of lymphoid cells transfected with the P2X(7) ATP receptor. J Biol Chem 1999, 274:33206-33208.
    • (1999) J Biol Chem , vol.274 , pp. 33206-33208
    • Baricordi, O.R.1    Melchiorri, L.2    Adinolfi, E.3    Falzoni, S.4    Chiozzi, P.5    Buell, G.6
  • 38
    • 0037079543 scopus 로고    scopus 로고
    • P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia
    • Adinolfi E., Melchiorri L., Falzoni S., Chiozzi P., Morelli A., Tieghi A., et al. P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia. Blood 2002, 99:706-708.
    • (2002) Blood , vol.99 , pp. 706-708
    • Adinolfi, E.1    Melchiorri, L.2    Falzoni, S.3    Chiozzi, P.4    Morelli, A.5    Tieghi, A.6
  • 39
    • 21844450590 scopus 로고    scopus 로고
    • Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth
    • Adinolfi E., Callegari M.G., Ferrari D., Bolognesi C., Minelli M., Wieckowski M.R., et al. Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth. Mol Biol Cell 2005, 16:3260-3272.
    • (2005) Mol Biol Cell , vol.16 , pp. 3260-3272
    • Adinolfi, E.1    Callegari, M.G.2    Ferrari, D.3    Bolognesi, C.4    Minelli, M.5    Wieckowski, M.R.6
  • 40
    • 1642483466 scopus 로고    scopus 로고
    • Early prostate cancer detected using expression of non-functional cytolytic P2X7 receptors
    • Slater M., Danieletto S., Gidley-Baird A., Teh L.C., Barden J.A. Early prostate cancer detected using expression of non-functional cytolytic P2X7 receptors. Histopathology 2004, 44:206-215.
    • (2004) Histopathology , vol.44 , pp. 206-215
    • Slater, M.1    Danieletto, S.2    Gidley-Baird, A.3    Teh, L.C.4    Barden, J.A.5
  • 41
    • 65649141604 scopus 로고    scopus 로고
    • Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis
    • Adinolfi E., Callegari M.G., Cirillo M., Pinton P., Giorgi C., Cavagna D., et al. Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis. J Biol Chem 2009, 284:10120-10128.
    • (2009) J Biol Chem , vol.284 , pp. 10120-10128
    • Adinolfi, E.1    Callegari, M.G.2    Cirillo, M.3    Pinton, P.4    Giorgi, C.5    Cavagna, D.6
  • 42
    • 31544480053 scopus 로고    scopus 로고
    • The P2X7 receptor sustains the growth of human neuroblastoma cells through a substance P-dependent mechanism
    • Raffaghello L., Chiozzi P., Falzoni S., Di Virgilio F., Pistoia V. The P2X7 receptor sustains the growth of human neuroblastoma cells through a substance P-dependent mechanism. Cancer Res 2006, 66:907-914.
    • (2006) Cancer Res , vol.66 , pp. 907-914
    • Raffaghello, L.1    Chiozzi, P.2    Falzoni, S.3    Di Virgilio, F.4    Pistoia, V.5
  • 43
    • 62749172817 scopus 로고    scopus 로고
    • Functional decreases in P2X7 receptors are associated with retinoic acid-induced neuronal differentiation of Neuro-2a neuroblastoma cells
    • Wu P.Y., Lin Y.C., Chang C.L., Lu H.T., Chin C.H., Hsu T.T., et al. Functional decreases in P2X7 receptors are associated with retinoic acid-induced neuronal differentiation of Neuro-2a neuroblastoma cells. Cell Signal 2009, 21:881-891.
    • (2009) Cell Signal , vol.21 , pp. 881-891
    • Wu, P.Y.1    Lin, Y.C.2    Chang, C.L.3    Lu, H.T.4    Chin, C.H.5    Hsu, T.T.6
  • 45
    • 64849087753 scopus 로고    scopus 로고
    • The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore
    • Monif M., Reid C.A., Powell K.L., Smart M.L., Williams D.A. The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore. J Neurosci 2009, 29:3781-3791.
    • (2009) J Neurosci , vol.29 , pp. 3781-3791
    • Monif, M.1    Reid, C.A.2    Powell, K.L.3    Smart, M.L.4    Williams, D.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.