Fluazinam targets mitochondrial complex I to induce reactive oxygen species-dependent cytotoxicity in SH-SY5Y cells

Neurochemistry International

Volumn 60, Issue 8, 2012, Pages 773-781

  Lee, Jeong Eun ^a   Kang, Jin Sun ^a   Ki, Yeo Woon ^a   Park, Jae Hyeon ^a   Shin, In Chul ^a   Koh, Hyun Chul ^a  

^a Hanyang University   (South Korea)

Author keywords

Apoptosis; Fluazinam; JNK; Mitochondrial complex I activity; p38; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CYTOCHROME C; DOPAMINE; FLUAZINAM; FUNGICIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); STRESS ACTIVATED PROTEIN KINASE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; DOPAMINERGIC NERVE CELL; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL;

AMINOPYRIDINES; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

BOTRYTIS;

EID: 84861164698     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.03.007     Document Type: Article

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