메뉴 건너뛰기




Volumn , Issue , 2012, Pages

Overexpression of S6 kinase 1 in brain tumours is associated with induction of hypoxia-responsive genes and predicts patients' survival

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN; PROTEIN NEDD9; S6 KINASE; TRANSCRIPTION FACTOR SOX4; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; VASCULOTROPIN A;

EID: 84861090959     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2012/416927     Document Type: Article
Times cited : (31)

References (49)
  • 2
    • 67349238177 scopus 로고    scopus 로고
    • The changing epidemiology of paediatric brain tumours: A review from the hospital for sick children
    • Kaderali Z., Lamberti-Pasculli M., Rutka J. T., The changing epidemiology of paediatric brain tumours: a review from the hospital for sick children Child's Nervous System 2009 25 7 787 793
    • (2009) Child's Nervous System , vol.25 , Issue.7 , pp. 787-793
    • Kaderali, Z.1    Lamberti-Pasculli, M.2    Rutka, J.T.3
  • 3
    • 14244265590 scopus 로고    scopus 로고
    • Epidemiology and etiology of gliomas
    • DOI 10.1007/s00401-005-0991-y
    • Ohgaki H., Kleihues P., Epidemiology and etiolog (Pubitemid 40287792)
    • (2005) Acta Neuropathologica , vol.109 , Issue.1 , pp. 93-108
    • Ohgaki, H.1    Kleihues, P.2
  • 4
    • 77957067789 scopus 로고    scopus 로고
    • Prevalence estimates for primary brain tumors in the United States by age, gender, behavior, and histology
    • Porter K. R., McCarthy B. J., Freels S., Kim Y., Davis F. G., Prevalence estimates for primary brain tumors in the United States by age, gender, behavior, and histology Neuro-Oncology 2010 12 6 520 527
    • (2010) Neuro-Oncology , vol.12 , Issue.6 , pp. 520-527
    • Porter, K.R.1    McCarthy, B.J.2    Freels, S.3    Kim, Y.4    Davis, F.G.5
  • 7
    • 34447343798 scopus 로고    scopus 로고
    • Lessons learned in the development of targeted therapy for malignant gliomas
    • DOI 10.1158/1535-7163.MCT-07-0047
    • Omuro A. M., Faivre S., Raymond E., Lessons learned in the development of targeted therapy for malignant gliomas Molecular Cancer Therapeutics 2007 6 7 1909 1919 (Pubitemid 47052481)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.7 , pp. 1909-1919
    • Omuro, A.M.P.1    Faivre, S.2    Raymond, E.3
  • 8
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I., Sawyers C. L., The phosphatidylinositol 3-kinase-AKT pathway in human cancer Nature Reviews Cancer 2002 2 7 489 501 (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 10
    • 16444368462 scopus 로고    scopus 로고
    • Genetic pathways to glioblastomas
    • DOI 10.1111/j.1440-1789.2004.00600.x
    • Ohgaki H., Genetic pathways to glioblastomas Neuropathology 2005 25 1 1 7 (Pubitemid 40477707)
    • (2005) Neuropathology , vol.25 , Issue.1 , pp. 1-7
    • Ohgaki, H.1
  • 12
    • 3042823868 scopus 로고    scopus 로고
    • The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
    • DOI 10.1200/JCO.2004.07.193
    • Chakravarti A., Zhai G., Suzuki Y., Sarkesh S., Black P. M., Muzikansky A., Loeffler J. S., The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas Journal of Clinical Oncology 2004 22 10 1926 1933 (Pubitemid 41095185)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.10 , pp. 1926-1933
    • Chakravarti, A.1    Zhai, G.2    Suzuki, Y.3    Sarkesh, S.4    Black, P.M.5    Muzikansky, A.6    Loeffler, J.S.7
  • 13
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • DOI 10.1101/gad.1212704
    • Hay N., Sonenberg N., Upstream and downstream of mTOR Genes and Development 2004 18 16 1926 1945 (Pubitemid 39071573)
    • (2004) Genes and Development , vol.18 , Issue.16 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 14
    • 32944456143 scopus 로고    scopus 로고
    • Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions
    • DOI 10.1158/0008-5472.CAN-05-3375
    • Kaper F., Dornhoefer N., Giaccia A. J., Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions Cancer Research 2006 66 3 1561 1569 (Pubitemid 43259938)
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1561-1569
    • Kaper, F.1    Dornhoefer, N.2    Giaccia, A.J.3
  • 15
    • 2342559981 scopus 로고    scopus 로고
    • The TOR pathway: A target for cancer therapy
    • Bjornsti M. A., Houghton P. J., The TOR pathway: a target for cancer therapy Nature Reviews Cancer 2004 4 5 335 348 (Pubitemid 38579480)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.5 , pp. 335-348
    • Bjornsti, M.-A.1    Houghton, P.J.2
  • 16
    • 0036225178 scopus 로고    scopus 로고
    • Inhibitors of mammalian target of rapamycin as novel antitumor agents: From bench to clinic
    • Huang S., Houghton P. J., Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic Current Opinion in Investigational Drugs 2002 3 2 295 304 (Pubitemid 34456089)
    • (2002) Current Opinion in Investigational Drugs , vol.3 , Issue.2 , pp. 295-304
    • Huang, S.1    Houghton, P.J.2
  • 17
    • 0036776168 scopus 로고    scopus 로고
    • A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling
    • DOI 10.1016/S0006-2952(02)01263-7, PII S0006295202012637
    • Chen J., Fang Y., A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling Biochemical Pharmacology 2002 64 7 1071 1077 (Pubitemid 35247814)
    • (2002) Biochemical Pharmacology , vol.64 , Issue.7 , pp. 1071-1077
    • Chen, J.1    Fang, Y.2
  • 18
    • 50349083186 scopus 로고    scopus 로고
    • Changes in tumor metabolism as readout for mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma
    • Wei L. H., Su H., Hildebrandt I. J., Phelps M. E., Czernin J., Weber W. A., Changes in tumor metabolism as readout for mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma Clinical Cancer Research 2008 14 11 3416 3426
    • (2008) Clinical Cancer Research , vol.14 , Issue.11 , pp. 3416-3426
    • Wei, L.H.1    Su, H.2    Hildebrandt, I.J.3    Phelps, M.E.4    Czernin, J.5    Weber, W.A.6
  • 20
    • 0034790016 scopus 로고    scopus 로고
    • MTOR, a novel target in breast cancer: The effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer
    • DOI 10.1677/erc.0.0080249
    • Yu K., Toral-Barza L., Discafani C., Zhang W. G., Skotnicki J., Frost P., Gibbons J. J., mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer Endocrine-Related Cancer 2001 8 3 249 258 (Pubitemid 32947647)
    • (2001) Endocrine-Related Cancer , vol.8 , Issue.3 , pp. 249-258
    • Yu, K.1    Toral-Barza, L.2    Discafani, C.3    Zhang, W.-G.4    Skotnicki, J.5    Frost, P.6    Gibbons, J.J.7
  • 22
    • 0141927222 scopus 로고    scopus 로고
    • Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer
    • DOI 10.1016/j.bbrc.2003.09.132
    • Gao N., Zhang Z., Jiang B. H., Shi X., Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer Biochemical and Biophysical Research Communications 2003 310 4 1124 1132 (Pubitemid 37237653)
    • (2003) Biochemical and Biophysical Research Communications , vol.310 , Issue.4 , pp. 1124-1132
    • Gao, N.1    Zhang, Z.2    Jiang, B.-H.3    Shi, X.4
  • 24
    • 53049084191 scopus 로고    scopus 로고
    • S6K1 plays a key role in glial transformation
    • Nakamura J. L., Garcia E., Pieper R. O., S6K1 plays a key role in glial transformation Cancer Research 2008 68 16 6516 6523
    • (2008) Cancer Research , vol.68 , Issue.16 , pp. 6516-6523
    • Nakamura, J.L.1    Garcia, E.2    Pieper, R.O.3
  • 25
    • 37549028779 scopus 로고    scopus 로고
    • Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function
    • Jastrzebski K., Hannan K. M., Tchoubrieva E. B., Hannan R. D., Pearson R. B., Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function Growth Factors 2007 25 4 209 226
    • (2007) Growth Factors , vol.25 , Issue.4 , pp. 209-226
    • Jastrzebski, K.1    Hannan, K.M.2    Tchoubrieva, E.B.3    Hannan, R.D.4    Pearson, R.B.5
  • 30
    • 58149218352 scopus 로고    scopus 로고
    • Cellular oxygen sensing, signalling and how to survive translational arrest in hypoxia
    • Fhling M., Cellular oxygen sensing, signalling and how to survive translational arrest in hypoxia Acta Physiologica 2009 195 2 205 230
    • (2009) Acta Physiologica , vol.195 , Issue.2 , pp. 205-230
    • Fhling, M.1
  • 31
    • 34547134517 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif
    • DOI 10.1074/jbc.M611782200
    • Land S. C., Tee A. R., Hypoxia-inducible factor 1 is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif The Journal of Biological Chemistry 2007 282 28 20534 20543 (Pubitemid 47100043)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.28 , pp. 20534-20543
    • Land, S.C.1    Tee, A.R.2
  • 32
    • 54949110530 scopus 로고    scopus 로고
    • Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinoma
    • Li W., Tan D., Zhang Z., Liang J. J., Brown R. E., Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinoma Oncology Reports 2008 20 4 713 719
    • (2008) Oncology Reports , vol.20 , Issue.4 , pp. 713-719
    • Li, W.1    Tan, D.2    Zhang, Z.3    Liang, J.J.4    Brown, R.E.5
  • 33
    • 32444433450 scopus 로고    scopus 로고
    • Hypoxia-induced energy stress regulates mRNA translation and cell growth
    • DOI 10.1016/j.molcel.2006.01.010, PII S1097276506000116
    • Liu L., Cash T. P., Jones R. G., Keith B., Thompson C. B., Simon M. C., Hypoxia-induced energy stress regulates mRNA translation and cell growth Molecular Cell 2006 21 4 521 531 (Pubitemid 43228007)
    • (2006) Molecular Cell , vol.21 , Issue.4 , pp. 521-531
    • Liu, L.1    Cash, T.P.2    Jones, R.G.3    Keith, B.4    Thompson, C.B.5    Simon, M.C.6
  • 38
    • 0035884608 scopus 로고    scopus 로고
    • Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis
    • Rickman D. S., Bobek M. P., Misek D. E., Kuick R., Blaivas M., Kurnit D. M., Taylor J., Hanash S. M., Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis Cancer Research 2001 61 18 6885 6891 (Pubitemid 32896514)
    • (2001) Cancer Research , vol.61 , Issue.18 , pp. 6885-6891
    • Rickman, D.S.1    Bobek, M.P.2    Misek, D.E.3    Kuick, R.4    Blaivas, M.5    Kurnit, D.M.6    Taylor, J.7    Hanash, S.M.8
  • 39
    • 25444448993 scopus 로고    scopus 로고
    • Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas
    • DOI 10.1158/0008-5472.CAN-05-1204
    • Bredel M., Bredel C., Juric D., Harsh G. R., Vogel H., Recht L. D., Sikic B. I., Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas Cancer Research 2005 65 19 8679 8689 (Pubitemid 41377355)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8679-8689
    • Bredel, M.1    Bredel, C.2    Juric, D.3    Harsh, G.R.4    Vogel, H.5    Recht, L.D.6    Sikic, B.I.7
  • 41
    • 0036531922 scopus 로고    scopus 로고
    • Comparative gene expression profile analysis of neurofibromatosis 1-associated and sporadic pilocytic astrocytomas
    • Gutmann D. H., Hedrick N. M., Li J., Nagarajan R., Perry A., Watson M. A., Comparative gene expression profile analysis of neurofibromatosis 1-associated and sporadic pilocytic astrocytomas Cancer Research 2002 62 7 2085 2091 (Pubitemid 34408456)
    • (2002) Cancer Research , vol.62 , Issue.7 , pp. 2085-2091
    • Gutmann, D.H.1    Hedrick, N.M.2    Li, J.3    Nagarajan, R.4    Perry, A.5    Watson, M.A.6
  • 42
    • 0042425741 scopus 로고    scopus 로고
    • Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction
    • van den Boom J., Wolter M., Kuick R., Misek D. E., Youkilis A. S., Wechsler D. S., Sommer C., Reifenberger G., Hanash S. M., Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction American Journal of Pathology 2003 163 3 1033 1043 (Pubitemid 37040139)
    • (2003) American Journal of Pathology , vol.163 , Issue.3 , pp. 1033-1043
    • Van Den Boom, J.1    Wolter, M.2    Kuick, R.3    Misek, D.E.4    Youkilis, A.S.5    Wechsler, D.S.6    Sommer, C.7    Reifenberger, G.8    Hanash, S.M.9
  • 44
    • 34547574720 scopus 로고    scopus 로고
    • A New Mutational aktivation in the PI3K Pathway
    • DOI 10.1016/j.ccr.2007.07.014, PII S1535610807002097
    • Brugge J., Hung M. C., Mills G. B., A new mutational aktivation in the PI3K pathway Cancer Cell 2007 12 2 104 107 (Pubitemid 47199129)
    • (2007) Cancer Cell , vol.12 , Issue.2 , pp. 104-107
    • Brugge, J.1    Hung, M.-C.2    Mills, G.B.3
  • 46
    • 0033119602 scopus 로고    scopus 로고
    • Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer
    • Couch F. J., Wang X. Y., Wu G. J., Qian J., Jenkins R. B., James C. D., Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer Cancer Research 1999 59 7 1408 1411 (Pubitemid 29160100)
    • (1999) Cancer Research , vol.59 , Issue.7 , pp. 1408-1411
    • Couch, F.J.1    Wang, X.-Y.2    Wu, G.-J.3    Qian, J.4    Jenkins, R.B.5    James, C.D.6
  • 49
    • 79960532978 scopus 로고    scopus 로고
    • Targeting tumour angiogenesis with small molecule inhibitors of hypoxia inducible factor
    • Nordgren I. K., Tavassoli A., Targeting tumour angiogenesis with small molecule inhibitors of hypoxia inducible factor Chemical Society Reviews 2011 40 8 4307 4317
    • (2011) Chemical Society Reviews , vol.40 , Issue.8 , pp. 4307-4317
    • Nordgren, I.K.1    Tavassoli, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.