메뉴 건너뛰기




Volumn 31, Issue 1, 2012, Pages

A selective aryl hydrocarbon receptor modulator 3,3'-Diindolylmethane inhibits gastric cancer cell growth

Author keywords

3,3' Diindolylmethane; Aryl hydrocarbon receptor; Cytochrome P4501A1; Gastric cancer

Indexed keywords

3,3' DIINDOLYLMETHANE; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; RESVERATROL; 3,3'-DIINDOLYLMETHANE; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; STILBENE DERIVATIVE;

EID: 84861009528     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-31-46     Document Type: Article
Times cited : (61)

References (33)
  • 3
    • 0027922810 scopus 로고
    • Roel of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction
    • Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer and signal transduction. Nebert DW, Puga A, Vasiliou V, Ann NY Acad Sci 1993 685 624 640 10.1111/j.1749-6632.1993.tb35928.x 8395783 (Pubitemid 23238548)
    • (1993) Annals of the New York Academy of Sciences , vol.685 , pp. 624-640
    • Nebert, D.W.1    Puga, A.2    Vasiliou, V.3
  • 4
    • 21844468556 scopus 로고    scopus 로고
    • Recent advances in molecular diagnosis and therapy of gastric cancer
    • DOI 10.1159/000083602
    • Recent advances in molecular diagnosis and therapy of gastric cancer. Chen J, Rocken C, Malfertheiner P, Ebert MP, Dig Dis 2004 22 380 385 10.1159/000083602 15812163 (Pubitemid 41201479)
    • (2004) Digestive Diseases , vol.22 , Issue.4 , pp. 380-385
    • Chen, J.1    Rocken, C.2    Malfertheiner, P.3    Ebert, M.P.A.4
  • 5
    • 47249090908 scopus 로고    scopus 로고
    • Expression and activity of aryl hydrocarbon receptors in development and cancer
    • Expression and activity of aryl hydrocarbon receptors in development and cancer. Gasiewicz TA, Crit Rev Eukaryot Gene Expr 2008 18 279 321 10.1615/CritRevEukarGeneExpr.v18.i4.10 18652561 (Pubitemid 351991362)
    • (2008) Critical Reviews in Eukaryotic Gene Expression , vol.18 , Issue.4 , pp. 279-321
    • Gasiewicz, T.A.1    Henry, E.C.2    Collins, L.L.3
  • 6
    • 61449200566 scopus 로고    scopus 로고
    • Overexpression of cytochrome P450 1B1 in advanced non-small cell lung cancer: A potential therapeutic target
    • 19331196
    • Overexpression of cytochrome P450 1B1 in advanced non-small cell lung cancer: a potential therapeutic target. Su JM, Lin P, Wang CK, Chang H, Anticancer Res 2009 29 509 515 19331196
    • (2009) Anticancer Res , vol.29 , pp. 509-515
    • Su, J.M.1    Lin, P.2    Wang, C.K.3    Chang, H.4
  • 8
    • 61449138610 scopus 로고    scopus 로고
    • The selective aryl hydrocarbon receptor modulator 6-methyl-1,3,8- trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice
    • 10.1016/j.bcp.2008.12.015 19166822
    • The selective aryl hydrocarbon receptor modulator 6-methyl-1,3,8- trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice. Fritz WA, Lin TM, Safe S, Moore RW, Peterson RE, Biochem Pharmacol 2009 77 1151 1160 10.1016/j.bcp.2008.12.015 19166822
    • (2009) Biochem Pharmacol , vol.77 , pp. 1151-1160
    • Fritz, W.A.1    Lin, T.M.2    Safe, S.3    Moore, R.W.4    Peterson, R.E.5
  • 9
    • 65649114010 scopus 로고    scopus 로고
    • Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer
    • 10.3748/wjg.15.1719 19360915
    • Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. Peng TL, Chen J, Mao W, Liu X, Tao Y, Chen LZ, Chen MH, World J Gastroenterol 2009 15 1719 1729 10.3748/wjg.15.1719 19360915
    • (2009) World J Gastroenterol , vol.15 , pp. 1719-1729
    • Peng, T.L.1    Chen, J.2    Mao, W.3    Liu, X.4    Tao, Y.5    Chen, L.Z.6    Chen, M.H.7
  • 10
    • 34447511096 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein
    • DOI 10.1016/j.febslet.2007.03.046, PII S0014579307003171, Cellular Stress
    • The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein. Barouki R, Coumoul X, Fernandez-Salguero PM, FEBS Lett 2007 581 3608 3615 10.1016/j.febslet.2007.03.046 17412325 (Pubitemid 47080995)
    • (2007) FEBS Letters , vol.581 , Issue.19 , pp. 3608-3615
    • Barouki, R.1    Coumoul, X.2    Fernandez-Salguero, P.M.3
  • 12
    • 0023179020 scopus 로고
    • Structure-activity relationships of dietary indoles: A proposed mechanism of action as modifiers of xenobiotic metabolism
    • Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolism. Bradfield CA, Bjeldanes LF, J Toxicol Environ Health 1987 21 311 323 10.1080/15287398709531021 3495667 (Pubitemid 17090147)
    • (1987) Journal of Toxicology and Environmental Health , vol.21 , Issue.3 , pp. 311-323
    • Bradfield, C.A.1    Bjeldanes, L.F.2
  • 13
    • 0029959032 scopus 로고    scopus 로고
    • Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells
    • DOI 10.1016/0006-2952(96)00060-3
    • Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells. Chen I, Safe S, Bjeldanes L, Biochem Pharmacol 1996 51 1069 1076 10.1016/0006-2952(96)00060-3 8866829 (Pubitemid 26104627)
    • (1996) Biochemical Pharmacology , vol.51 , Issue.8 , pp. 1069-1076
    • Chen, I.1    Safe, S.2    Bjeldanes, L.3
  • 14
    • 33845964968 scopus 로고    scopus 로고
    • Activation of caspase-8 contributes to 3,3′-diindolylmethane- induced apoptosis in colon cancer cells
    • Activation of caspase-8 contributes to 3,3'-Diindolylmethane-induced apoptosis in colon cancer cells. Kim EJ, Park SY, Shin HK, Kwon DY, Surh YJ, Park JH, J Nutr 2007 137 31 36 17182797 (Pubitemid 46052855)
    • (2007) Journal of Nutrition , vol.137 , Issue.1 , pp. 31-36
    • Eun, J.K.1    So, Y.P.2    Shin, H.-K.3    Dae, Y.K.4    Surh, Y.-J.5    Park, J.H.Y.6
  • 15
    • 0037026632 scopus 로고    scopus 로고
    • Increased aryl hydrocarbon receptor expression offers a potential therapeutic target in pancreatic cancer
    • 10.1038/sj.onc.1205633 12203118
    • Increased aryl hydrocarbon receptor expression offers a potential therapeutic target in pancreatic cancer. Koliopanos A, Kleeff J, Xiao Y, Safe S, Zimmermann A, Büchler MW, Friess H, Oncogene 2002 21 6059 6070 10.1038/sj.onc.1205633 12203118
    • (2002) Oncogene , vol.21 , pp. 6059-6070
    • Koliopanos, A.1    Kleeff, J.2    Xiao, Y.3    Safe, S.4    Zimmermann, A.5    Büchler, M.W.6    Friess, H.7
  • 16
    • 0032535055 scopus 로고    scopus 로고
    • Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor
    • Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor. Ciolino HP, Daschner PJ, Yeh GC, Cancer Res 1998 58 5707 5712 9865727 (Pubitemid 29006410)
    • (1998) Cancer Research , vol.58 , Issue.24 , pp. 5707-5712
    • Ciolino, H.P.1    Daschner, P.J.2    Yeh, G.C.3
  • 17
    • 0042700218 scopus 로고    scopus 로고
    • Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene
    • DOI 10.1002/jat.916
    • Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene. Revel A, Raanani H, Younglai E, Xu J, Rogers I, Han R, Savouret JF, Casper RF, J Appl Toxicol 2003 23 255 261 10.1002/jat.916 12884409 (Pubitemid 36950295)
    • (2003) Journal of Applied Toxicology , vol.23 , Issue.4 , pp. 255-261
    • Revel, A.1    Raanani, H.2    Younglai, E.3    Xu, J.4    Rogers, I.5    Han, R.6    Savouret, J.-F.7    Casper, R.F.8
  • 19
    • 0036615860 scopus 로고    scopus 로고
    • Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers (Review)
    • 12011988
    • Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers (Review). Safe S, McDougal A, Int J Oncol 2002 20 1123 1128 12011988
    • (2002) Int J Oncol , vol.20 , pp. 1123-1128
    • Safe, S.1    McDougal, A.2
  • 20
    • 38349188939 scopus 로고    scopus 로고
    • Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo
    • 10.1007/s00204-007-0232-3 17899013
    • Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo. Sugihara K, Okayama T, Kitamura S, Yamashita K, Yasuda M, Miyairi S, Minobe Y, Ohta S, Arch Toxicol 2008 82 5 11 10.1007/s00204-007-0232-3 17899013
    • (2008) Arch Toxicol , vol.82 , pp. 5-11
    • Sugihara, K.1    Okayama, T.2    Kitamura, S.3    Yamashita, K.4    Yasuda, M.5    Miyairi, S.6    Minobe, Y.7    Ohta, S.8
  • 21
    • 0031715037 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
    • DOI 10.1093/carcin/19.9.1631
    • Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Chen I, McDougal A, Wang F, Safe S, Carcinogenesis 1998 19 1631 1639 10.1093/carcin/19.9.1631 9771935 (Pubitemid 28441867)
    • (1998) Carcinogenesis , vol.19 , Issue.9 , pp. 1631-1639
    • Chen, I.1    McDougal, A.2    Wang, F.3    Safe, S.4
  • 22
    • 0027457434 scopus 로고
    • Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation
    • DOI 10.1016/0006-2952(93)90258-X
    • Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation. Jellinck PH, Forkert PG, Riddick DS, Okey AB, Michnovicz JJ, Bradlow HL, Biochem Pharmacol 1993 45 1129 1136 10.1016/0006-2952(93)90258-X 8384853 (Pubitemid 23079991)
    • (1993) Biochemical Pharmacology , vol.45 , Issue.5 , pp. 1129-1136
    • Jellinck, P.H.1    Forkert, P.G.2    Riddick, D.S.3    Okey, A.B.4    Michnovicz, J.J.5    Bradlow, H.L.6
  • 23
    • 0037145007 scopus 로고    scopus 로고
    • The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation
    • DOI 10.1016/S0009-2797(02)00065-0, PII S0009279702000650
    • The mechanism of AH receptor protein downregulation (degradation) and its impact on AH receptormediated gene regulation. Pollenz RS, Chem Biol Interact 2002 141 41 61 10.1016/S0009-2797(02)00065-0 12213384 (Pubitemid 35223204)
    • (2002) Chemico-Biological Interactions , vol.141 , Issue.1-2 , pp. 41-61
    • Pollenz, R.S.1
  • 24
    • 0035501476 scopus 로고    scopus 로고
    • Involvement of a post-transcriptional mechanism in the inhibition of CYP1A1 expression by resveratrol in breast cancer cells
    • DOI 10.1016/S0006-2952(01)00763-8, PII S0006295201007638
    • Involvement of a post-transcriptional mechanism in the inhibition of CYP1A1 expression by resveratrol in breast cancer cells. Lee JE, Safe S, Biochem Pharmacol 2001 62 1113 1124 10.1016/S0006-2952(01)00763-8 11597580 (Pubitemid 32971677)
    • (2001) Biochemical Pharmacology , vol.62 , Issue.8 , pp. 1113-1124
    • Lee, J.-E.1    Safe, S.2
  • 25
    • 0035984590 scopus 로고    scopus 로고
    • 3,30-Diindolylmethane (DIM) induces a G1 cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression
    • 10.1093/carcin/23.8.1297 12151347
    • 3,30-Diindolylmethane (DIM) induces a G1 cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression. Hong C, Kim HA, Firestone GL, Bjeldanes LF, Carcinogenesis 2002 23 1297 1305 10.1093/carcin/23.8.1297 12151347
    • (2002) Carcinogenesis , vol.23 , pp. 1297-1305
    • Hong, C.1    Kim, H.A.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 26
    • 67649641442 scopus 로고    scopus 로고
    • Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells
    • 10.1186/1471-230X-9-39 19480695
    • Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells. Choi HJ, Lim do Y, Park JH, BMC Gastroenterol 2009 9 39 10.1186/1471-230X-9-39 19480695
    • (2009) BMC Gastroenterol , vol.9 , pp. 39
    • Choi, H.J.1    Lim Do, Y.2    Park, J.H.3
  • 27
    • 67649464189 scopus 로고    scopus 로고
    • 3,3'-Diindolylmethane induces a G(1) arrest in human prostate cancer cells irrespective of androgen receptor and p53 status
    • 10.1016/j.bcp.2009.05.008 19433067
    • 3,3'-Diindolylmethane induces a G(1) arrest in human prostate cancer cells irrespective of androgen receptor and p53 status. Vivar OI, Lin CL, Firestone GL, Bjeldanes LF, Biochem Pharmacol 2009 78 469 476 10.1016/j.bcp.2009.05.008 19433067
    • (2009) Biochem Pharmacol , vol.78 , pp. 469-476
    • Vivar, O.I.1    Lin, C.L.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 28
    • 0035984590 scopus 로고    scopus 로고
    • 3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression
    • 10.1093/carcin/23.8.1297 12151347
    • 3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression. Hong C, Kim HA, Firestone GL, Bjeldanes LF, Carcinogenesis 2002 23 1297 1305 10.1093/carcin/23.8.1297 12151347
    • (2002) Carcinogenesis , vol.23 , pp. 1297-1305
    • Hong, C.1    Kim, H.A.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 29
    • 77953483368 scopus 로고    scopus 로고
    • Anticancer properties of indole compounds: Mechanism of apoptosis induction and role in chemotherapy
    • 10.2174/138945010791170923 20298156
    • Anticancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy. Ahmad A, Sakr WA, Rahman KM, Curr Drug Targets 2010 11 652 666 10.2174/138945010791170923 20298156
    • (2010) Curr Drug Targets , vol.11 , pp. 652-666
    • Ahmad, A.1    Sakr, W.A.2    Rahman, K.M.3
  • 30
    • 33646386136 scopus 로고    scopus 로고
    • Gene expression profiling revealed survivin as a target of 3,3'-diindolylmethane-induced cell growth inhibition and apoptosis in breast cancer cells
    • 10.1158/0008-5472.CAN-05-3918 16651453
    • Gene expression profiling revealed survivin as a target of 3,3'-diindolylmethane-induced cell growth inhibition and apoptosis in breast cancer cells. Rahman KW, Li Y, Wang Z, Sarkar SH, Sarkar FH, Cancer Res 2006 66 4952 4960 10.1158/0008-5472.CAN-05-3918 16651453
    • (2006) Cancer Res , vol.66 , pp. 4952-4960
    • Rahman, K.W.1    Li, Y.2    Wang, Z.3    Sarkar, S.H.4    Sarkar, F.H.5
  • 31
    • 70350500114 scopus 로고    scopus 로고
    • Down-regulation of uPA and uPAR by 3,3'-diindolylmethane contributes to the inhibition of cell growth and migration of breast cancer cells
    • 10.1002/jcb.22323 19693769
    • Down-regulation of uPA and uPAR by 3,3'-diindolylmethane contributes to the inhibition of cell growth and migration of breast cancer cells. Ahmad A, Kong D, Wang Z, Sarkar SH, Banerjee S, Sarkar FH, J Cell Biochem 2009 108 916 925 10.1002/jcb.22323 19693769
    • (2009) J Cell Biochem , vol.108 , pp. 916-925
    • Ahmad, A.1    Kong, D.2    Wang, Z.3    Sarkar, S.H.4    Banerjee, S.5    Sarkar, F.H.6
  • 32
    • 35948988561 scopus 로고    scopus 로고
    • Inactivation of NF-κB by 3,3′-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells
    • DOI 10.1158/1535-7163.MCT-07-0336
    • Inactivation of NF-kappaB by 3,3'-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells. Rahman KM, Ali S, Aboukameel A, Sarkar SH, Wang Z, Philip PA, Sakr WA, Raz A, Mol Cancer Ther 2007 6 2757 2765 10.1158/1535-7163.MCT-07-0336 17913854 (Pubitemid 350064073)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.10 , pp. 2757-2765
    • Rahman, K.M.W.1    Ali, S.2    Aboukameel, A.3    Sarkar, S.H.4    Wang, Z.5    Philip, P.A.6    Sakr, W.A.7    Raz, A.8
  • 33
    • 17444430817 scopus 로고    scopus 로고
    • Selective growth regulatory and pro-apoptotic effects of DIM is mediated by Akt and NF-kappaB pathways in prostate cancer cells
    • Front Selective growth regulatory and pro-apoptotic effects of DIM is mediated by AKT and NF-kappaB pathways in prostate cancer cells. Li Y, Chinni SR, Sarkar FH, Biosci 2005 10 236 243 (Pubitemid 40543031)
    • (2005) Frontiers in Bioscience , vol.10 , Issue.1 , pp. 236-243
    • Li, Y.1    Chinni, S.R.2    Sarkar, F.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.