Involvement of a post-transcriptional mechanism in the inhibition of CYP1A1 expression by resveratrol in breast cancer cells

Biochemical Pharmacology

Volumn 62, Issue 8, 2001, Pages 1113-1124

  Lee, Jeong Eun ^a   Safe, Stephen ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Ah receptor; CYP1A1; Inhibition; Resveratrol

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOSOL RECEPTOR; DACTINOMYCIN; FLAVONE DERIVATIVE; MESSENGER RNA; PROTEIN INHIBITOR; RESVERATROL;

ARTICLE; BREAST CARCINOMA; BREAST CELL; CANCER CELL; CELL STRAIN; CELL STRAIN MCF 7; CELL TRANSPORT; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INDUCTION; GENE ACTIVITY; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENE INSERTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN TRANSPORT; REPORTER GENE; RNA DEGRADATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CYTOCHROME P-450 CYP1A1; ENZYME STABILITY; GENE SILENCING; HUMANS; RECEPTORS, ARYL HYDROCARBON; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; STILBENES; TUMOR CELLS, CULTURED;

EID: 0035501476     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00763-8     Document Type: Article

References (36)

1. Direct HPLC analysis of cis- and trans-resveratrol and piceid isomers in Spanish red Vitis vinifera wines
2. Piceid, the major resveratrol derivative in grape juices
3. An antiplatelet principle of Veratrum formosanum
4. Inhibition of human LDL oxidation by resveratrol
5. Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes
6. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease
7. The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury
8. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
9. Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
10. Antiproliferative effect of synthetic resveratrol on human breast epithelial cells
11. Is resveratrol an estrogen agonist in growing rats?
12. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
13. Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells
14. Effect of concentrated red grape juice consumption on serum antioxidant capacity and low-density lipoprotein oxidation
15. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells
16. Resveratrol has antagonist activity on the aryl hydrocarbon receptor: Implications for prevention of dioxin toxicity
17. Resveratrol is a selective human cytochrome P450 1A1 inhibitor
18. Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor
19. Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol
20. Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially
21. Diosmin and diosmetin are agonists of the aryl hydrocarbon receptor that differentially affect cytochrome P450 1A1 activity
22. Identification of 3′-methoxy-4′-nitroflavone as a pure aryl hydrocarbon receptor antagonist and evidence for more than one form of the Ah receptor in MCF-7 human breast cancer cells
23. Characterization of the rat H4IIE bioassay for evaluation of environmental samples containing polynuclear aromatic hydrocarbons (PAHs)
24. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
25. Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells
26. Flavone antagonists bind competitively with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to the aryl hydrocarbon receptor but inhibit nuclear uptake and transformation
27. Analysis of structural requirements for Ah receptor antagonist activity: Ellipticines, flavones, and related compounds
28. The steroid hormone dehydroepiandrosterone inhibits CYP1A1 expression in vitro by a post-transcriptional mechanism
29. Crosstalk between estrogen receptor α and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes
30. Mortality associated with moderate intakes of wine, beer, or spirits
31. Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study
32. Review of moderate alcohol consumption and reduced risk of coronary heart disease: Is the effect due to beer, wine, or spirits?
33. Development of selective aryl hydrocarbon receptor modulators (SARMs) for treatment of breast cancer
34. Antiestrogenic activities of alternate substituted polychlorinated dibenzofurans in MCF-7 human breast cancer cells
35. Ah receptor-based chemical screening bioassays: Application and limitations for the detection of Ah receptor agonists
36. Resveratrol inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells