Stable gene targeting in human cells using single-strand oligonucleotides with modified bases

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Rios, Xavier ^a   Briggs, Adrian W ^a   Chistodoulou, Danos ^a   Gorham, Josh M ^a   Seidman, Jonathan G ^a   Church, George M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE; PHOSPHOROTHIOIC ACID; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN;

ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR IMMUNITY; CHEMICAL BOND; CONTROLLED STUDY; EGFP GENE; GENE EXPRESSION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC ENGINEERING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MISMATCH REPAIR; MODIFIER GENE; PROCESS OPTIMIZATION; SEQUENCE ANALYSIS; UPREGULATION; BASE MISPAIRING; DNA REPAIR; GENETICS; HELA CELL; NUCLEOTIDE SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

BASE PAIR MISMATCH; BASE SEQUENCE; CELL PROLIFERATION; DNA REPAIR; GENE TARGETING; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84861004618     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036697     Document Type: Article

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