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Volumn 287, Issue 20, 2012, Pages 16246-16255

Deregulation of DNA damage response pathway by intercellular contact

Author keywords

[No Author keywords available]

Indexed keywords

ANTICANCER TREATMENT; CANCER CELLS; DNA BINDING ABILITY; DNA DAMAGE RESPONSE; DNA DAMAGES; DNA-BINDING; GENOMIC INTEGRITY; HYPERPHOSPHORYLATION; UBIQUITIN LIGASES;

EID: 84860879026     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.337212     Document Type: Article
Times cited : (8)

References (39)
  • 1
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers, J. H. (2001) Genome maintenance mechanisms for preventing cancer. Nature 411, 366-374
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 2
    • 33646106590 scopus 로고    scopus 로고
    • γH2AX and MDC1. Anchoring the DNA damage-response machinery to broken chromosomes
    • Stucki, M., and Jackson, S. P. (2006) γH2AX and MDC1. Anchoring the DNA damage-response machinery to broken chromosomes. DNA Repair 5, 534-543
    • (2006) DNA Repair , vol.5 , pp. 534-543
    • Stucki, M.1    Jackson, S.P.2
  • 3
    • 0042991379 scopus 로고    scopus 로고
    • Histone H2AX: A dosage-dependent suppressor of oncogenic translocations and tumors
    • DOI 10.1016/S0092-8674(03)00566-X
    • Bassing, C. H., Suh, H., Ferguson, D. O., Chua, K. F., Manis, J., Eckersdorff, M., Gleason, M., Bronson, R., Lee, C., and Alt, F. W. (2003) Histone H2AX. A dosage-dependent suppressor of oncogenic translocations and tumors. Cell 114, 359-370 (Pubitemid 36962934)
    • (2003) Cell , vol.114 , Issue.3 , pp. 359-370
    • Bassing, C.H.1    Suh, H.2    Ferguson, D.O.3    Chua, K.F.4    Manis, J.5    Eckersdorff, M.6    Gleason, M.7    Bronson, R.8    Lee, C.9    Alt, F.W.10
  • 4
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response. Making it safe to play with knives
    • Ciccia, A., and Elledge, S. J. (2010) The DNA damage response. Making it safe to play with knives. Mol. Cell 40, 179-204
    • (2010) Mol. Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 5
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: Signaling, repair and the cancer connection
    • DOI 10.1038/85798
    • Khanna, K. K., and Jackson, S. P. (2001) DNA double-strand breaks. Signaling, repair, and the cancer connection. Nat. Genet. 27, 247-254 (Pubitemid 32201842)
    • (2001) Nature Genetics , vol.27 , Issue.3 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 8
    • 29244434544 scopus 로고    scopus 로고
    • MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
    • DOI 10.1016/j.cell.2005.09.038, PII S0092867405011657
    • Stucki, M., Clapperton, J. A., Mohammad, D., Yaffe, M. B., Smerdon, S. J., and Jackson, S. P. (2005) MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123, 1213-1226 (Pubitemid 41821780)
    • (2005) Cell , vol.123 , Issue.7 , pp. 1213-1226
    • Stucki, M.1    Clapperton, J.A.2    Mohammad, D.3    Yaffe, M.B.4    Smerdon, S.J.5    Jackson, S.P.6
  • 13
    • 63849187827 scopus 로고    scopus 로고
    • Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
    • Cook, P. J., Ju, B. G., Telese, F., Wang, X., Glass, C. K., and Rosenfeld, M. G. (2009) Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 458, 591-596
    • (2009) Nature , vol.458 , pp. 591-596
    • Cook, P.J.1    Ju, B.G.2    Telese, F.3    Wang, X.4    Glass, C.K.5    Rosenfeld, M.G.6
  • 14
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma, S., Chen, B. P., Murphy, M., Kurimasa, A., and Chen, D. J. (2001) ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 276, 42462-42467
    • (2001) J. Biol. Chem. , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 15
    • 0032526401 scopus 로고    scopus 로고
    • Differential nuclear translocation and transactivation potential of β- Catenin and plakoglobin
    • DOI 10.1083/jcb.141.6.1433
    • Simcha, I., Shtutman, M., Salomon, D., Zhurinsky, J., Sadot, E., Geiger, B., and Ben-Ze'ev, A. (1998) Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin. J. Cell Biol. 141, 1433-1448 (Pubitemid 28289918)
    • (1998) Journal of Cell Biology , vol.141 , Issue.6 , pp. 1433-1448
    • Simcha, I.1    Shtutman, M.2    Salomon, D.3    Zhurinsky, J.4    Sadot, E.5    Geiger, B.6    Ben-Ze'ev, A.7
  • 16
    • 0025752664 scopus 로고
    • The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression
    • Nagafuchi, A., Takeichi, M., and Tsukita, S. (1991) The 102-kDa cadherin-associated protein. Similarity to vinculin and posttranscriptional regulation of expression. Cell 65, 849-857 (Pubitemid 121001316)
    • (1991) Cell , vol.65 , Issue.5 , pp. 849-857
    • Nagafuchi, A.1    Takeichi, M.2    Tsukita, S.3
  • 17
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • DOI 10.1016/S0960-9822(00)00610-2
    • Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., and Bonner, W. M. (2000) A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10, 886-895 (Pubitemid 30647617)
    • (2000) Current Biology , vol.10 , Issue.15 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 18
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • DOI 10.1074/jbc.273.10.5858
    • Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., and Bonner, W. M. (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273, 5858-5868 (Pubitemid 28124064)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.10 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 20
    • 36249031962 scopus 로고    scopus 로고
    • RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly
    • DOI 10.1016/j.cell.2007.09.041, PII S0092867407012706
    • Huen, M. S., Grant, R., Manke, I., Minn, K., Yu, X., Yaffe, M. B., and Chen, J. (2007) RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 131, 901-914 (Pubitemid 350138083)
    • (2007) Cell , vol.131 , Issue.5 , pp. 901-914
    • Huen, M.S.Y.1    Grant, R.2    Manke, I.3    Minn, K.4    Yu, X.5    Yaffe, M.B.6    Chen, J.7
  • 21
    • 75949124023 scopus 로고    scopus 로고
    • Assembly of checkpoint and repair machineries at DNA damage sites
    • Huen, M. S., and Chen, J. (2010) Assembly of checkpoint and repair machineries at DNA damage sites. Trends Biochem. Sci. 35, 101-108
    • (2010) Trends Biochem. Sci. , vol.35 , pp. 101-108
    • Huen, M.S.1    Chen, J.2
  • 22
    • 36248966246 scopus 로고    scopus 로고
    • RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins
    • DOI 10.1016/j.cell.2007.09.040, PII S0092867407012718
    • Mailand, N., Bekker-Jensen, S., Faustrup, H., Melander, F., Bartek, J., Lukas, C., and Lukas, J. (2007) RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131, 887-900 (Pubitemid 350138084)
    • (2007) Cell , vol.131 , Issue.5 , pp. 887-900
    • Mailand, N.1    Bekker-Jensen, S.2    Faustrup, H.3    Melander, F.4    Bartek, J.5    Lukas, C.6    Lukas, J.7
  • 23
    • 1942538492 scopus 로고    scopus 로고
    • ATM and DNA-PK Function Redundantly to Phosphorylate H2AX after Exposure to Ionizing Radiation
    • DOI 10.1158/0008-5472.CAN-03-3207
    • Stiff, T., O'Driscoll, M., Rief, N., Iwabuchi, K., Löbrich, M., and Jeggo, P. A. (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 64, 2390-2396 (Pubitemid 38523891)
    • (2004) Cancer Research , vol.64 , Issue.7 , pp. 2390-2396
    • Stiff, T.1    O'Driscoll, M.2    Rief, N.3    Iwabuchi, K.4    Lobrich, M.5    Jeggo, P.A.6
  • 24
    • 0034643433 scopus 로고    scopus 로고
    • Differential interaction of plakoglobin and β-catenin with the ubiquitin-proteasome system
    • Sadot, E., Simcha, I., Iwai, K., Ciechanover, A., Geiger, B., and Ben-Ze'ev, A. (2000) Differential interaction of plakoglobin and β-catenin with the ubiquitin-proteasome system. Oncogene 19, 1992-2001 (Pubitemid 30229412)
    • (2000) Oncogene , vol.19 , Issue.16 , pp. 1992-2001
    • Sadot, E.1    Simcha, I.2    Iwai, K.3    Ciechanover, A.4    Geiger, B.5    Ben-Ze'ev, A.6
  • 25
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of β-catenin with the transcription factor LEF- 1
    • DOI 10.1038/382638a0
    • Behrens, J., von Kries, J. P., Kühl, M., Bruhn, L., Wedlich, D., Grosschedl, R., and Birchmeier, W. (1996) Functional interaction of β-catenin with the transcription factor LEF-1. Nature 382, 638-642 (Pubitemid 26268958)
    • (1996) Nature , vol.382 , Issue.6592 , pp. 638-642
    • Behrens, J.1    Von Kries, J.P.2    Kuhl, M.3    Bruhn, L.4    Wedlich, D.5    Grosschedl, R.6    Birchmeier, W.7
  • 26
    • 0026756891 scopus 로고
    • Plakoglobin and β-catenin. Distinct but closely related
    • Butz, S., Stappert, J., Weissig, H., and Kemler, R. (1992) Plakoglobin and β-catenin. Distinct but closely related. Science 257, 1142-1144
    • (1992) Science , vol.257 , pp. 1142-1144
    • Butz, S.1    Stappert, J.2    Weissig, H.3    Kemler, R.4
  • 27
    • 0022993985 scopus 로고
    • Plakoglobin: A protein common to different kinds of intercellular adhering junctions
    • Cowin, P., Kapprell, H. P., Franke, W. W., Tamkun, J., and Hynes, R. O. (1986) Plakoglobin. A protein common to different kinds of intercellular adhering junctions. Cell 46, 1063-1073 (Pubitemid 17182730)
    • (1986) Cell , vol.46 , Issue.7 , pp. 1063-1073
    • Cowin, P.1    Kapprell, H.-P.2    Franke, W.W.3
  • 28
    • 0026630994 scopus 로고
    • Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization
    • Hirano, S., Kimoto, N., Shimoyama, Y., Hirohashi, S., and Takeichi, M. (1992) Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization. Cell 70, 293-301
    • (1992) Cell , vol.70 , pp. 293-301
    • Hirano, S.1    Kimoto, N.2    Shimoyama, Y.3    Hirohashi, S.4    Takeichi, M.5
  • 29
    • 0027185632 scopus 로고
    • From cadherins to catenins. Cytoplasmic protein interactions and regulation of cell adhesion
    • Kemler, R. (1993) From cadherins to catenins. Cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9, 317-321
    • (1993) Trends Genet. , vol.9 , pp. 317-321
    • Kemler, R.1
  • 30
    • 0026316099 scopus 로고
    • A homolog of the armadillo protein in Drosophila (Plakoglobin) associated with E-cadherin
    • McCrea, P. D., Turck, C. W., and Gumbiner, B. (1991) A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science 254, 1359-1361 (Pubitemid 21917467)
    • (1991) Science , vol.254 , Issue.5036 , pp. 1359-1361
    • Mccrea, P.D.1    Turck, C.W.2    Gumbiner, B.3
  • 31
    • 77149179101 scopus 로고    scopus 로고
    • Adherens junction. Molecular architecture and regulation
    • Meng, W., and Takeichi, M. (2009) Adherens junction. Molecular architecture and regulation. Cold Spring Harb. Perspect. Biol. 1, a002899
    • (2009) Cold Spring Harb. Perspect. Biol. , vol.1
    • Meng, W.1    Takeichi, M.2
  • 32
    • 1342343924 scopus 로고    scopus 로고
    • Plakoglobin (γ-catenin) has TCF/LEF family-dependent transcriptional activity in β-catenin-deficient cell line
    • DOI 10.1038/sj.onc.1207254
    • Maeda, O., Usami, N., Kondo, M., Takahashi, M., Goto, H., Shimokata, K., Kusugami, K., and Sekido, Y. (2004) Plakoglobin (γ-catenin) has TCF/LEF family-dependent transcriptional activity in β-catenin-deficient cell line. Oncogene 23, 964-972 (Pubitemid 38250942)
    • (2004) Oncogene , vol.23 , Issue.4 , pp. 964-972
    • Maeda, O.1    Usami, N.2    Kondo, M.3    Takahashi, M.4    Goto, H.5    Shimokata, K.6    Kusugami, K.7    Sekido, Y.8
  • 33
    • 77953720192 scopus 로고    scopus 로고
    • ATM-dependent chromatin changes silence transcription in cis to DNA double strand breaks
    • Shanbhag, N. M., Rafalska-Metcalf, I. U., Balane-Bolivar, C., Janicki, S. M., and Greenberg, R. A. (2010) ATM-dependent chromatin changes silence transcription in cis to DNA double strand breaks. Cell 141, 970-981
    • (2010) Cell , vol.141 , pp. 970-981
    • Shanbhag, N.M.1    Rafalska-Metcalf, I.U.2    Balane-Bolivar, C.3    Janicki, S.M.4    Greenberg, R.A.5
  • 34
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response. Putting checkpoints in perspective
    • Zhou, B. B., and Elledge, S. J. (2000) The DNA damage response. Putting checkpoints in perspective. Nature 408, 433-439
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2
  • 35
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D., and Weinberg, R. A. (2000) The hallmarks of cancer. Cell 100, 57-70 (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 36
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • DOI 10.1038/362847a0
    • Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., and Jacks, T. (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362, 847-849 (Pubitemid 23132161)
    • (1993) Nature , vol.362 , Issue.6423 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 37
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double strand breaks in vivo
    • Rogakou, E. P., Boon, C., Redon, C., and Bonner, W. M. (1999) Megabase chromatin domains involved in DNA double strand breaks in vivo. J. Cell Biol. 146, 905-916
    • (1999) J. Cell Biol. , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 39
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • DOI 10.1038/nature01368
    • Bakkenist, C. J., and Kastan, M. B. (2003) DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421, 499-506 (Pubitemid 36168436)
    • (2003) Nature , vol.421 , Issue.6922 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2


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