BMP and cancer: The yin and yang of stem cells;BMP et cancer: Le yin et le yang des cellules souches

Medecine/Sciences

Volumn 28, Issue 4, 2012, Pages 416-422

  Sagorny, Karen ^a,b   Chapellier, Marion ^a,b   Laperrousaz, Bastien ^a,b   Maguer Satta, Véronique ^a,b  

^a UNIVERSITÉ DE LYON   (France)

^b CENTRE DE RECHERCHE EN CANCÉROLOGIE DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

ADULT; ADULT STEM CELL; ANIMAL; BIOLOGICAL MODEL; CANCER STEM CELL; CELL DIFFERENTIATION; GENETICS; HOMEOSTASIS; HUMAN; METABOLISM; NEOPLASM; PATHOLOGY; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; STEM CELL NICHE;

ADULT; ADULT STEM CELLS; ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; HOMEOSTASIS; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; NEOPLASTIC STEM CELLS; SIGNAL TRANSDUCTION; STEM CELL NICHE;

EID: 84860870980     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/2012284020     Document Type: Review

References (34)

1. Kimura K, Toyooka S, Tsukuda K, et al. The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas. Oncol Rep 2008;20:1265-8.
2. Bhatia M, Bonnet D, Wu D, et al. Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J Exp Med 1999;189:1139-48.
3. Mira H, Andreu Z, Suh H, et al. Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell 2010;7:78-89.
4. Bonaguidi MA, McGuire T, Hu M, et al. LIF and BMP signaling generate separate and discrete types of GFAP-expressing cells. Development 2005;132:5503-14. (Pubitemid 43125877)
5. Kobielak K, Stokes N, de la Cruz J, et al. Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling. Proc Natl Acad Sci USA 2007;104:10063-8. (Pubitemid 47175263)
6. He XC, Zhang J, Tong WG, et al. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet 2004;36:1117-21. (Pubitemid 41184475)
7. Vicente Lopez MA, Vazquez Garcia MN, Entrena A, et al. Low doses of bone morphogenetic protein 4 increase the survival of human adipose-derived stem cells maintaining their stemness and multipotency. Stem Cells Dev 2011;20:1011-9.
8. Maguer-Satta V, Bartholin L, Jeanpierre S, et al. Regulation of human erythropoiesis by activin A, BMP2, and BMP4, members of the TGFbeta family. Exp Cell Res 2003;282:110-20. (Pubitemid 36259905)
9. Jeanpierre S, Nicolini FE, Kaniewski B, et al. BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling. Blood 2008;112:3154-63.
10. Kang Q, Song WX, Luo Q, et al. A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev 2009;18:545-59.
11. Hua H, Zhang YQ, Dabernat S, et al. BMP4 regulates pancreatic progenitor cell expansion through Id2. J Biol Chem 2006;281:13574-80. (Pubitemid 43855271)
12. Liu SY, Zhang ZY, Song YC, et al. SVZa neural stem cells differentiate into distinct lineages in response to BMP4. Exp Neurol 2004;190:109-21.
13. Rajan P, Panchision DM, Newell LF, McKay RD. BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells. J Cell Biol 2003;161:911-21. (Pubitemid 36718424)
14. Zhang J, Niu C, Ye L, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003;425:836-41. (Pubitemid 37351467)
15. Lim DA, Tramontin AD, Trevejo JM, et al. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 2000;28:713-26. (Pubitemid 32038066)
16. Rendl M, Polak L, Fuchs E. BMP signaling in dermal papilla cells is required for their hair follicleinductive properties. Genes Dev 2008;22:543-57. (Pubitemid 351272760)
17. Haramis AP, Begthel H, van den BM, et al. De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine. Science 2004;303:1684-6. (Pubitemid 38338329)
18. Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-7. (Pubitemid 27298715)
19. Schatton T, Frank MH. Cancer stem cells and human malignant melanoma. Pigment Cell Melanoma Res 2008;21:39-55. (Pubitemid 351421465)
20. Lee J, Son MJ, Woolard K, et al. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell 2008;13:69-80. (Pubitemid 350309742)
21. Piccirillo SG, Reynolds BA, Zanetti N, et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature 2006;444:761-5. (Pubitemid 44949605)
22. Ruoslahti E. Fibronectin and its integrin receptors in cancer. Adv Cancer Res 1999;76:1-20. (Pubitemid 29190879)
23. Hideshima T, Bergsagel PL, Kuehl WM, Anderson KC. Advances in biology of multiple myeloma: clinical applications. Blood 2004;104:607-18. (Pubitemid 38970551)
24. Simon M, Grandage VL, Linch DC, Khwaja A. Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia. Oncogene 2005;24:2410-20. (Pubitemid 40546699)
25. Paszek MJ, Zahir N, Johnson KR, et al. Tensional homeostasis and the malignant phenotype. Cancer Cell 2005;8:241-54. (Pubitemid 41317594)
26. Buesche G, Ganser A, Schlegelberger B, et al. Marrow fibrosis and its relevance during imatinib treatment of chronic myeloid leukemia. Leukemia 2007;21:2420-7. (Pubitemid 350148883)
27. Bock O, Hoftmann J, Theophile K, et al. Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines. Am J Pathol 2008;172:951-60. (Pubitemid 351519992)
28. Tibullo D, Giallongo C, La Cava P, et al. Effects of imatinib mesylate in osteoblastogenesis. Exp Hematol 2009;37:461-8.
29. Thiele J, Kvasnicka HM, Schmitt-Graeff A, et al. Bone marrow changes in chronic myelogenous leukaemia after long-term treatment with the tyrosine kinase inhibitor STI571: an immunohistochemical study on 75 patients. Histopathology 2005;46:540-50. (Pubitemid 40632311)
30. Liu F, Bloch N, Bhushan KR, et al. Humoral bone morphogenetic protein 2 is sufficient for inducing breast cancer microcalcification. Mol Imaging 2008;7:175-86.
31. Lataillade JJ, Brunet de la Grange P, Uzan G, Le Bousse-Kerdilès MC. Les cellules souches ont-elles l'âge de leur niche? À la recherche d'un sérum de jouvence. Med Sci (Paris) 2010;26:582-5.
32. Cachat A, Villaudy J, Rigal D, Gazzolo L, Duc Dodon M. Les souris ne sont pas des hommes et pourtant⋯ Ce que les souris humanisées nous apprennent sur les maladies infectieuses. Med Sci (Paris) 2012;28:63-8.
33. Joubert D, Hollande F, Jay P, Legraverend C. Les cellules souches intestinales: 30 ans d'une histoire exemplaire. Med Sci (Paris) 2009;25:441-4.
34. Häfner S, Coulombel L. L'oligarchie contestée des cellules souches cancéreuses. Med Sci (Paris) 2009;25:227-8.