메뉴 건너뛰기




Volumn 112, Issue 8, 2008, Pages 3154-3163

BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENIC PROTEIN RECEPTOR; CARRIER PROTEIN; FOLLISTATIN; JANUS KINASE; MAMMALIAN TARGET OF RAPAMYCIN; STAT PROTEIN; THROMBOPOIETIN; UNCLASSIFIED DRUG; ACTIVIN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; CD34 ANTIGEN; JANUS KINASE 1; PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA;

EID: 54049103653     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-03-145326     Document Type: Article
Times cited : (49)

References (47)
  • 1
    • 0035100290 scopus 로고    scopus 로고
    • Adhesion receptors on haematopoietic progenitor cells
    • Chan JY, Watt SM. Adhesion receptors on haematopoietic progenitor cells. Br J Haematol. 2001;112:541-557.
    • (2001) Br J Haematol , vol.112 , pp. 541-557
    • Chan, J.Y.1    Watt, S.M.2
  • 2
    • 31044442504 scopus 로고    scopus 로고
    • Megakaryocyte biology and related disorders
    • Pang L, Weiss MJ, Poncz M. Megakaryocyte biology and related disorders. J Clin Invest. 2005; 115:3332-3338.
    • (2005) J Clin Invest , vol.115 , pp. 3332-3338
    • Pang, L.1    Weiss, M.J.2    Poncz, M.3
  • 3
    • 0037440420 scopus 로고    scopus 로고
    • Regulation of human erythropoiesis by activin A, BMP2, and BMP4, members of the TGFbeta family
    • Maguer-Satta V, Bartholin L, Jeanpierre S, et al. Regulation of human erythropoiesis by activin A, BMP2, and BMP4, members of the TGFbeta family. Exp Cell Res. 2003;282:110-120.
    • (2003) Exp Cell Res , vol.282 , pp. 110-120
    • Maguer-Satta, V.1    Bartholin, L.2    Jeanpierre, S.3
  • 4
    • 0141613833 scopus 로고    scopus 로고
    • Transforming growth factorbeta signaling in normal and malignant hematopoiesis
    • Kim SJ. Letterio J. Transforming growth factorbeta signaling in normal and malignant hematopoiesis. Leukemia. 2003;17:1731-1737.
    • (2003) Leukemia , vol.17 , pp. 1731-1737
    • Kim, S.J.1    Letterio, J.2
  • 5
    • 0036459180 scopus 로고    scopus 로고
    • The role of activin a in regulation of hemopoiesis
    • Shav-Tal Y, Zipori D. The role of activin a in regulation of hemopoiesis. Stem Cells. 2002;20:493-500.
    • (2002) Stem Cells , vol.20 , pp. 493-500
    • Shav-Tal, Y.1    Zipori, D.2
  • 6
    • 33646435309 scopus 로고    scopus 로고
    • The stem cell niches in bone
    • Yin T, Li L. The stem cell niches in bone. J Clin Invest. 2006;116:1195-1201.
    • (2006) J Clin Invest , vol.116 , pp. 1195-1201
    • Yin, T.1    Li, L.2
  • 7
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature. 2003;425:836-841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3
  • 8
    • 0036838550 scopus 로고    scopus 로고
    • Emergence of muscle and neural hematopoiesis in humans
    • Jay KE, Gallacher L, Bhatia M. Emergence of muscle and neural hematopoiesis in humans. Blood. 2002;100:3193-3202.
    • (2002) Blood , vol.100 , pp. 3193-3202
    • Jay, K.E.1    Gallacher, L.2    Bhatia, M.3
  • 9
    • 1342309778 scopus 로고    scopus 로고
    • FLRG, member of the follistatin family, a new player in hematopoiesis
    • Maguer-Satta V, Rimokh R. FLRG, member of the follistatin family, a new player in hematopoiesis. Mol Cell Endocrinol. 2004;225:109-118.
    • (2004) Mol Cell Endocrinol , vol.225 , pp. 109-118
    • Maguer-Satta, V.1    Rimokh, R.2
  • 10
    • 29144432833 scopus 로고    scopus 로고
    • A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin
    • Maguer-Satta V, Forissier S, Bartholin L. et al. A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin. Exp Cell Res. 2006;312: 434-442.
    • (2006) Exp Cell Res , vol.312 , pp. 434-442
    • Maguer-Satta, V.1    Forissier, S.2    Bartholin, L.3
  • 11
    • 0029793060 scopus 로고    scopus 로고
    • The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis
    • Maeno M, Mead PE, Kelley C, et al. The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis. Blood. 1996;88:1965-1972.
    • (1996) Blood , vol.88 , pp. 1965-1972
    • Maeno, M.1    Mead, P.E.2    Kelley, C.3
  • 12
    • 0033526067 scopus 로고    scopus 로고
    • Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells
    • Bhatia M, Bonnet D. Wu D, et al. Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J Exp Med. 1999;189:1139-1148.
    • (1999) J Exp Med , vol.189 , pp. 1139-1148
    • Bhatia, M.1    Bonnet, D.2    Wu, D.3
  • 13
    • 33947587879 scopus 로고    scopus 로고
    • Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures
    • Kennedy M, D'Souza SL, Lynch-Kattman M, Schwantz S, Keller G. Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures. Blood. 2007;109:2679-2687.
    • (2007) Blood , vol.109 , pp. 2679-2687
    • Kennedy, M.1    D'Souza, S.L.2    Lynch-Kattman, M.3    Schwantz, S.4    Keller, G.5
  • 14
    • 0035261398 scopus 로고    scopus 로고
    • Self-renewal vs differentiation, a job for the mighty morphogens
    • Zon Ll. Self-renewal vs differentiation, a job for the mighty morphogens. Nat Immunol. 2001;2: 142-143.
    • (2001) Nat Immunol , vol.2 , pp. 142-143
    • Zon, L.1
  • 15
    • 3543035189 scopus 로고    scopus 로고
    • BMP4: Its role in development of the hematopoietic system and potential as a hematopoietic growth factor
    • Sadlon TJ, Lewis ID, D'Andrea RJ. BMP4: its role in development of the hematopoietic system and potential as a hematopoietic growth factor. Stem Cells. 2004;22:457-474.
    • (2004) Stem Cells , vol.22 , pp. 457-474
    • Sadlon, T.J.1    Lewis, I.D.2    D'Andrea, R.J.3
  • 16
    • 0032402116 scopus 로고    scopus 로고
    • Cooperative effects of growth factors involved in the induction of hematopoietic mesoderm
    • Huber TL, Zhou Y, Mead PE, Zon Ll. Cooperative effects of growth factors involved in the induction of hematopoietic mesoderm. Blood. 1998;92: 4128-4137.
    • (1998) Blood , vol.92 , pp. 4128-4137
    • Huber, T.L.1    Zhou, Y.2    Mead, P.E.3    Zon, L.4
  • 17
    • 33846442016 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 contributes to the maintenance of primitive cord blood hematopoietic progenitors in an ex vivo stromanon contact co-culture system
    • Hutton JF, Rozenkov V, Khor FS, D'Andrea RJ, Lewis ID. Bone morphogenetic protein 4 contributes to the maintenance of primitive cord blood hematopoietic progenitors in an ex vivo stromanon contact co-culture system. Stem Cells Dev. 2006;15:805-813.
    • (2006) Stem Cells Dev , vol.15 , pp. 805-813
    • Hutton, J.F.1    Rozenkov, V.2    Khor, F.S.3    D'Andrea, R.J.4    Lewis, I.D.5
  • 18
    • 0038457891 scopus 로고    scopus 로고
    • BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells
    • Rajan P, Panchision DM, Newell LF, McKay RD. BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells. J Cell Biol. 2003;161:911-921.
    • (2003) J Cell Biol , vol.161 , pp. 911-921
    • Rajan, P.1    Panchision, D.M.2    Newell, L.F.3    McKay, R.D.4
  • 19
    • 34249815542 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling in stem cells: One signal, many consequences
    • Wagner TU. Bone morphogenetic protein signaling in stem cells: one signal, many consequences. FEBS J. 2007;274:2968-2976.
    • (2007) FEBS J , vol.274 , pp. 2968-2976
    • Wagner, T.U.1
  • 20
    • 0029149656 scopus 로고
    • Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
    • Winnier G, Blessing M, Labosky PA, Hogan BL. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 1995;9:2105-2116.
    • (1995) Genes Dev , vol.9 , pp. 2105-2116
    • Winnier, G.1    Blessing, M.2    Labosky, P.A.3    Hogan, B.L.4
  • 21
    • 0028970392 scopus 로고
    • Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development
    • Johansson BM, Wiles MV. Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development. Mol Cell Biol. 1995;15:141-151.
    • (1995) Mol Cell Biol , vol.15 , pp. 141-151
    • Johansson, B.M.1    Wiles, M.V.2
  • 22
    • 0035880235 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 induces efficient hematopoietic differentiation of rhesus monkey embryonic stem cells in vitro
    • Li F, Lu S, Vida L, Thomson JA, Honig GR. Bone morphogenetic protein 4 induces efficient hematopoietic differentiation of rhesus monkey embryonic stem cells in vitro. Blood. 2001;98:335-342.
    • (2001) Blood , vol.98 , pp. 335-342
    • Li, F.1    Lu, S.2    Vida, L.3    Thomson, J.A.4    Honig, G.R.5
  • 23
    • 34748837360 scopus 로고    scopus 로고
    • Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis
    • Rev
    • Katoh M. Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis. Stem Cell Rev. 2007;3:30-38.
    • (2007) Stem Cell , vol.3 , pp. 30-38
    • Katoh, M.1
  • 24
    • 0034812344 scopus 로고    scopus 로고
    • Molecular and transcriptional regulation of megakaryocyte differentiation
    • Shivdasani RA. Molecular and transcriptional regulation of megakaryocyte differentiation. Stem Cells. 2001;19:397-407.
    • (2001) Stem Cells , vol.19 , pp. 397-407
    • Shivdasani, R.A.1
  • 25
    • 31044439372 scopus 로고    scopus 로고
    • The molecular mechanisms that control thrombopoiesis
    • Kaushansky K. The molecular mechanisms that control thrombopoiesis. J Clin Invest. 2005;115: 3339-3347.
    • (2005) J Clin Invest , vol.115 , pp. 3339-3347
    • Kaushansky, K.1
  • 26
    • 33645070791 scopus 로고    scopus 로고
    • Inhibition of TPO-induced MEK or mTOR activity induces opposite effects on the ploidy of human differentiating megakaryocytes
    • Guerriero R, Parolini I, Testa U, et al. Inhibition of TPO-induced MEK or mTOR activity induces opposite effects on the ploidy of human differentiating megakaryocytes. J Cell Sci. 2006;119:744-752.
    • (2006) J Cell Sci , vol.119 , pp. 744-752
    • Guerriero, R.1    Parolini, I.2    Testa, U.3
  • 27
    • 0036118717 scopus 로고    scopus 로고
    • Ex vivo expansion of megakaryocyte progenitor cells from normal bone marrow and peripheral blood and from patients with haematological malignancies
    • Blair A, Baker CL, Pamphilon DH, Judson PA. Ex vivo expansion of megakaryocyte progenitor cells from normal bone marrow and peripheral blood and from patients with haematological malignancies. Br J Haematol. 2002;116:912-919.
    • (2002) Br J Haematol , vol.116 , pp. 912-919
    • Blair, A.1    Baker, C.L.2    Pamphilon, D.H.3    Judson, P.A.4
  • 28
    • 33644769115 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation
    • Raslova H, Baccini V, Loussaief L, et al. Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation. Blood. 2006:107:2303-2310.
    • (2006) Blood , vol.107 , pp. 2303-2310
    • Raslova, H.1    Baccini, V.2    Loussaief, L.3
  • 29
    • 4143066998 scopus 로고    scopus 로고
    • Expression of bone morphogenetic proteins in stromal cells from human bone marrow long-term culture
    • Martinovic S, Mazic S, Kisic V, et al. Expression of bone morphogenetic proteins in stromal cells from human bone marrow long-term culture. J Histochem Cytochem. 2004;52:1159-1167.
    • (2004) J Histochem Cytochem , vol.52 , pp. 1159-1167
    • Martinovic, S.1    Mazic, S.2    Kisic, V.3
  • 30
    • 12344294485 scopus 로고    scopus 로고
    • Engagement of integrin alpha4beta1 enhances thrombopoietin-induced megakaryopoiesis
    • Fox NE, Kaushansky K. Engagement of integrin alpha4beta1 enhances thrombopoietin-induced megakaryopoiesis. Exp Hematol. 2005;33:94-99.
    • (2005) Exp Hematol , vol.33 , pp. 94-99
    • Fox, N.E.1    Kaushansky, K.2
  • 31
    • 16644379307 scopus 로고    scopus 로고
    • Generation of functional culture-derived platelets from CD34+ progenitor cells to study transgenes in the platelet environment
    • Ungerer M, Peluso M, Gillitzer A, et al. Generation of functional culture-derived platelets from CD34+ progenitor cells to study transgenes in the platelet environment. Circ Res. 2004;95:36-44.
    • (2004) Circ Res , vol.95 , pp. 36-44
    • Ungerer, M.1    Peluso, M.2    Gillitzer, A.3
  • 32
    • 0036464649 scopus 로고    scopus 로고
    • Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release
    • Mattia G, Vulcano F, Milazzo L, et al. Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release. Blood. 2002;99:888-897.
    • (2002) Blood , vol.99 , pp. 888-897
    • Mattia, G.1    Vulcano, F.2    Milazzo, L.3
  • 33
    • 0035007685 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 interferes with thrombopoietin-induced signal transduction in megakaryoblastic and erythroleukemic cells
    • Kalina U, Koschmieder S, Hofmann WK, et al. Transforming growth factor-beta1 interferes with thrombopoietin-induced signal transduction in megakaryoblastic and erythroleukemic cells. Exp Hematol. 2001;29:602-608.
    • (2001) Exp Hematol , vol.29 , pp. 602-608
    • Kalina, U.1    Koschmieder, S.2    Hofmann, W.K.3
  • 34
    • 34248335074 scopus 로고    scopus 로고
    • BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors
    • Perry JM, Harandi OF, Paulson RF. BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors. Blood. 2007;109:4494-4502.
    • (2007) Blood , vol.109 , pp. 4494-4502
    • Perry, J.M.1    Harandi, O.F.2    Paulson, R.F.3
  • 35
    • 34748864145 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis
    • Pick M, Azzola L, Mossman A, Stanley EG, Elefanty AG. Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis. Stem Cells. 2007;25:2206-2214.
    • (2007) Stem Cells , vol.25 , pp. 2206-2214
    • Pick, M.1    Azzola, L.2    Mossman, A.3    Stanley, E.G.4    Elefanty, A.G.5
  • 36
    • 0034122233 scopus 로고    scopus 로고
    • FOG acts as a repressor of red blood cell development in Xenopus
    • Deconinck AE, Mead PE, Tevosian SG, et al. FOG acts as a repressor of red blood cell development in Xenopus. Development. 2000;127: 2031-2040.
    • (2000) Development , vol.127 , pp. 2031-2040
    • Deconinck, A.E.1    Mead, P.E.2    Tevosian, S.G.3
  • 37
    • 0035912754 scopus 로고    scopus 로고
    • The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila
    • Fossett N, Tevosian SG, Gajewski K, et al. The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila. Proc Natl Acad Sci U S A. 2001;98:7342-7347.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 7342-7347
    • Fossett, N.1    Tevosian, S.G.2    Gajewski, K.3
  • 38
    • 0031910136 scopus 로고    scopus 로고
    • Hematopoietic deficiencies in c-mpl and TPO knockout mice
    • Murone M, Carpenter DA, de Sauvage FJ. Hematopoietic deficiencies in c-mpl and TPO knockout mice. Stem Cells. 1998;16:1-6.
    • (1998) Stem Cells , vol.16 , pp. 1-6
    • Murone, M.1    Carpenter, D.A.2    de Sauvage, F.J.3
  • 39
    • 0030788804 scopus 로고    scopus 로고
    • Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin
    • Bunting S, Widmer R, Lipari T, et al. Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin. Blood. 1997;90: 3423-3429.
    • (1997) Blood , vol.90 , pp. 3423-3429
    • Bunting, S.1    Widmer, R.2    Lipari, T.3
  • 40
    • 0035883096 scopus 로고    scopus 로고
    • Thrombocytopenic c-mpl(-/-) mice can produce a normal level of platelets after administration of 5-fluorouracil: The effect of age on the response
    • Levin J, Cocault L, Demerens C, et al. Thrombocytopenic c-mpl(-/-) mice can produce a normal level of platelets after administration of 5-fluorouracil: the effect of age on the response. Blood. 2001;98:1019-1027.
    • (2001) Blood , vol.98 , pp. 1019-1027
    • Levin, J.1    Cocault, L.2    Demerens, C.3
  • 41
    • 11144356721 scopus 로고    scopus 로고
    • Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
    • Avecilla ST, Hattori K, Heissig B, et al. Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nat Med. 2004;10: 64-71.
    • (2004) Nat Med , vol.10 , pp. 64-71
    • Avecilla, S.T.1    Hattori, K.2    Heissig, B.3
  • 42
    • 0034650935 scopus 로고    scopus 로고
    • The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor
    • Gainsford T, Nandurkar H, Metcalf D, et al. The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor. Blood. 2000;95:528-534.
    • (2000) Blood , vol.95 , pp. 528-534
    • Gainsford, T.1    Nandurkar, H.2    Metcalf, D.3
  • 43
    • 13944268297 scopus 로고    scopus 로고
    • Localization of bone morphogenetic proteins (BMPs)-2,-4, and -6 within megakaryocytes and platelets
    • Sipe JB, Zhang J, Waits C, et al. Localization of bone morphogenetic proteins (BMPs)-2,-4, and -6 within megakaryocytes and platelets. Bone. 2004;35:1316-1322.
    • (2004) Bone , vol.35 , pp. 1316-1322
    • Sipe, J.B.1    Zhang, J.2    Waits, C.3
  • 44
    • 34447106121 scopus 로고    scopus 로고
    • Cytokines for the treatment of thrombocytopenia
    • Ciurea SO, Hoffman R. Cytokines for the treatment of thrombocytopenia. Semin Hematol. 2007;44:166-182.
    • (2007) Semin Hematol , vol.44 , pp. 166-182
    • Ciurea, S.O.1    Hoffman, R.2
  • 45
    • 34447343823 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in clinical applications
    • Gautschi OP, Frey SP, Zellweger R. Bone morphogenetic proteins in clinical applications. Aust N Z J Surg. 2007;77:626-631.
    • (2007) Aust N Z J Surg , vol.77 , pp. 626-631
    • Gautschi, O.P.1    Frey, S.P.2    Zellweger, R.3
  • 46
    • 33947605189 scopus 로고    scopus 로고
    • HGF inhibits BMP-induced osteoblastogenesis: Possible implications for the bone disease of multiple myeloma
    • Standal T, Abildgaard N, Fagerli UM, et al. HGF inhibits BMP-induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma. Blood. 2007;109:3024-3030.
    • (2007) Blood , vol.109 , pp. 3024-3030
    • Standal, T.1    Abildgaard, N.2    Fagerli, U.M.3
  • 47
    • 0034142201 scopus 로고    scopus 로고
    • Expression of thrombopoietin and its receptor (c-mpl) in chronic myelogenous leukemia: Correlation with disease progression and response to therapy
    • Kaban K, Kantarjian H, Talpaz M, et al. Expression of thrombopoietin and its receptor (c-mpl) in chronic myelogenous leukemia: correlation with disease progression and response to therapy. Cancer. 2000;88:570-576.
    • (2000) Cancer , vol.88 , pp. 570-576
    • Kaban, K.1    Kantarjian, H.2    Talpaz, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.