-
1
-
-
65349154635
-
Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease
-
Aikawa E. Aikawa M. Libby P. Figueiredo J. Rusanescu G. Iwamoto Y. et al. (2009) Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease. Circulation 119: 1785–1794.
-
(2009)
Circulation
, vol.119
, pp. 1785-1794
-
-
Aikawa, E.1
Aikawa, M.2
Libby, P.3
Figueiredo, J.4
Rusanescu, G.5
Iwamoto, Y.6
-
5
-
-
59249091239
-
Atherosclerotic inflammation triggers osteogenic bone transformation in calcified and stenotic human aortic valves: still a matter of debate
-
Anger T. Carson W. Weyand M. Daniel W.G. Hoeher M. Garlichs C.D. (2009) Atherosclerotic inflammation triggers osteogenic bone transformation in calcified and stenotic human aortic valves: still a matter of debate. Exp Mol Pathol 86: 10–17.
-
(2009)
Exp Mol Pathol
, vol.86
, pp. 10-17
-
-
Anger, T.1
Carson, W.2
Weyand, M.3
Daniel, W.G.4
Hoeher, M.5
Garlichs, C.D.6
-
6
-
-
33947579076
-
Angiotensin receptor-1 blocker inhibits atherosclerotic changes and endothelial disruption of the aortic valve in hypercholesterolemic rabbits
-
Arishiro K. Hoshiga M. Negoro N. Jin D. Takai S. Miyazaki M. et al. (2007) Angiotensin receptor-1 blocker inhibits atherosclerotic changes and endothelial disruption of the aortic valve in hypercholesterolemic rabbits. J Am Coll Cardiol 49: 1482–1489.
-
(2007)
J Am Coll Cardiol
, vol.49
, pp. 1482-1489
-
-
Arishiro, K.1
Hoshiga, M.2
Negoro, N.3
Jin, D.4
Takai, S.5
Miyazaki, M.6
-
7
-
-
41349109161
-
Genomics: the next step to elucidate the etiology of calcific aortic valve stenosis
-
Boss Y. Mathieu P. Pibarot P. (2008) Genomics: the next step to elucidate the etiology of calcific aortic valve stenosis. J Am Coll Cardiol 51: 1327–1336.
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 1327-1336
-
-
Boss, Y.1
Mathieu, P.2
Pibarot, P.3
-
9
-
-
33646466212
-
Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation
-
2006.2002.2040v2001
-
Caira F.C. Stock S.R. Gleason T.G. McGee E.C. Huang J. Bonow R.O. et al. (2006) Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation. J Am Coll Cardiol 2006.2002.2040v2001: 1707–1712.
-
(2006)
J Am Coll Cardiol
, pp. 1707-1712
-
-
Caira, F.C.1
Stock, S.R.2
Gleason, T.G.3
McGee, E.C.4
Huang, J.5
Bonow, R.O.6
-
12
-
-
77954992963
-
Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents
-
Hakuno D. Kimura N. Yoshioka M. Mukai M. Kimura T. Okada Y. et al. (2010) Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents. J Clin Invest 120: 2292–2306.
-
(2010)
J Clin Invest
, vol.120
, pp. 2292-2306
-
-
Hakuno, D.1
Kimura, N.2
Yoshioka, M.3
Mukai, M.4
Kimura, T.5
Okada, Y.6
-
13
-
-
33745725939
-
Possible role for mast cell-derived cathepsin G in the adverse remodelling of stenotic aortic valves
-
Helske S. Syvaranta S. Kupari M. Lappalainen J. Laine M. Lommi J. et al. (2006 a) Possible role for mast cell-derived cathepsin G in the adverse remodelling of stenotic aortic valves. Eur Heart J 27: 1495–1504.
-
(2006)
Eur Heart J
, vol.27
, pp. 1495-1504
-
-
Helske, S.1
Syvaranta, S.2
Kupari, M.3
Lappalainen, J.4
Laine, M.5
Lommi, J.6
-
14
-
-
33746834187
-
Increased expression of elastolytic cathepsins S., K., and V and their inhibitor cystatin C in stenotic aortic valves
-
Helske S. Syvaranta S. Lindstedt K.A. Lappalainen J. Oorni K. Mayranpaa M.I. et al. (2006 b) Increased expression of elastolytic cathepsins S, K, and V and their inhibitor cystatin C in stenotic aortic valves. Arterioscler Thromb Vasc Biol 26: 1791–1798.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1791-1798
-
-
Helske, S.1
Syvaranta, S.2
Lindstedt, K.A.3
Lappalainen, J.4
Oorni, K.5
Mayranpaa, M.I.6
-
15
-
-
0028939368
-
Structural organization, expression and chromosomal mapping of the mouse cystatin-C-encoding gene (Cst3)
-
Huh C. Nagle J.W. Kozak C.A. Abrahamson M. Karlsson S. (1995) Structural organization, expression and chromosomal mapping of the mouse cystatin-C-encoding gene (Cst3). Gene 152: 221–226.
-
(1995)
Gene
, vol.152
, pp. 221-226
-
-
Huh, C.1
Nagle, J.W.2
Kozak, C.A.3
Abrahamson, M.4
Karlsson, S.5
-
16
-
-
0347004546
-
Receptor activator of nuclear factor [kappa] B ligand and osteoprotegerin regulate aortic valve calcification
-
Kaden J.J. Bickelhaupt S. Grobholz R. Haase K.K. (2004) Receptor activator of nuclear factor [kappa] B ligand and osteoprotegerin regulate aortic valve calcification. J Mol Cell Cardiol 36: 57–66.
-
(2004)
J Mol Cell Cardiol
, vol.36
, pp. 57-66
-
-
Kaden, J.J.1
Bickelhaupt, S.2
Grobholz, R.3
Haase, K.K.4
-
18
-
-
36348976915
-
The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology
-
Liu A.C. Joag V.R. Gotlieb A.I. (2007) The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology. Am J Pathol 171: 1407–1418.
-
(2007)
Am J Pathol
, vol.171
, pp. 1407-1418
-
-
Liu, A.C.1
Joag, V.R.2
Gotlieb, A.I.3
-
19
-
-
0347004543
-
Unbalanced RANKL / RANK pathway in aortic valve sclerosis
-
Mallat Z. Tedgui A. (2004) Unbalanced RANKL / RANK pathway in aortic valve sclerosis. J Mol Cell Cardiol 36: 17–19.
-
(2004)
J Mol Cell Cardiol
, vol.36
, pp. 17-19
-
-
Mallat, Z.1
Tedgui, A.2
-
20
-
-
70149123248
-
Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development
-
Mead T. Yutzev K. (2009) Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development. Proc Natl Acad Sci U S A 106: 14420–14425.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14420-14425
-
-
Mead, T.1
Yutzev, K.2
-
21
-
-
77955384490
-
Activated Notch 1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors
-
Meier-Stiegen F. Schwanbeck R. Bernoth K. Martini S. Hieronymus T. Ruau D. et al. (2010) Activated Notch 1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors. PloS ONE 5: e11481.
-
(2010)
PloS ONE
, vol.5
, pp. e11481
-
-
Meier-Stiegen, F.1
Schwanbeck, R.2
Bernoth, K.3
Martini, S.4
Hieronymus, T.5
Ruau, D.6
-
22
-
-
38349118289
-
Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis
-
Meng X. Ao L. Song Y. Babu A. Yang X. Wang M. et al. (2008) Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis. Am J Physiol Cell Physiol 294: C29–C35.
-
(2008)
Am J Physiol Cell Physiol
, vol.294
, pp. C29-C35
-
-
Meng, X.1
Ao, L.2
Song, Y.3
Babu, A.4
Yang, X.5
Wang, M.6
-
23
-
-
49849089138
-
Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans
-
Miller J.D. Chu Y. Brooks R.M. Richenbacher W.E. Pena-Silva R. Heistad D.D. (2008) Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans. J Am Coll Cardiol 52: 843–850.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 843-850
-
-
Miller, J.D.1
Chu, Y.2
Brooks, R.M.3
Richenbacher, W.E.4
Pena-Silva, R.5
Heistad, D.D.6
-
24
-
-
9344271129
-
Mechanisms of aortic valve calcification
-
Mohler E.R. III (2004) Mechanisms of aortic valve calcification. Am J Cardiol 94: 1396–1402.
-
(2004)
Am J Cardiol
, vol.94
, pp. 1396-1402
-
-
Mohler, E.R.1
-
26
-
-
0142053965
-
Association between apolipoprotein E alleles and calcific valvular heart disease
-
Novaro G.M. Sachar R. Pearce G.L. Sprecher D.L. Griffin B.P. (2003) Association between apolipoprotein E alleles and calcific valvular heart disease. Circulation 108: 1804–1808.
-
(2003)
Circulation
, vol.108
, pp. 1804-1808
-
-
Novaro, G.M.1
Sachar, R.2
Pearce, G.L.3
Sprecher, D.L.4
Griffin, B.P.5
-
27
-
-
0034768262
-
The vitamin D receptor genotype predisposes to the development of calcific aortic valve stenosis
-
Ortlepp J.R. Hoffmann R. Ohme F. Lauscher J. Bleckmann F. Hanrath P. (2001) The vitamin D receptor genotype predisposes to the development of calcific aortic valve stenosis. Heart 85: 635–638.
-
(2001)
Heart
, vol.85
, pp. 635-638
-
-
Ortlepp, J.R.1
Hoffmann, R.2
Ohme, F.3
Lauscher, J.4
Bleckmann, F.5
Hanrath, P.6
-
28
-
-
33747161337
-
Role of human valve interstitial cells in valve calcification and their response to atorvastatin
-
Osman L. Yacoub M.H. Latif N. Amrani M. Chester A.H. (2006) Role of human valve interstitial cells in valve calcification and their response to atorvastatin. Circulation 114: I-547–I-552.
-
(2006)
Circulation
, vol.114
, pp. I-547-I-552
-
-
Osman, L.1
Yacoub, M.H.2
Latif, N.3
Amrani, M.4
Chester, A.H.5
-
29
-
-
0027991976
-
Characterization of the early lesion of degenerative valvular aortic stenosis. Histological and immunohistochemical studies
-
Otto C.M. Kuusisto J. Reichenbach D.D. Gown A.M. O'Brien K.D. (1994) Characterization of the early lesion of degenerative valvular aortic stenosis. Histological and immunohistochemical studies. Circulation 90: 844–853.
-
(1994)
Circulation
, vol.90
, pp. 844-853
-
-
Otto, C.M.1
Kuusisto, J.2
Reichenbach, D.D.3
Gown, A.M.4
O'Brien, K.D.5
-
31
-
-
79952539058
-
Do statins improve outcomes and delay the progression of non-rheumatic calcific aortic stenosis?
-
Parolari A. Tremoli E. Cavallotti L. Trezzi M. Kassem S. Loardi C. et al. (2011) Do statins improve outcomes and delay the progression of non-rheumatic calcific aortic stenosis? Heart 97: 523–529.
-
(2011)
Heart
, vol.97
, pp. 523-529
-
-
Parolari, A.1
Tremoli, E.2
Cavallotti, L.3
Trezzi, M.4
Kassem, S.5
Loardi, C.6
-
32
-
-
77949388887
-
Reduced Sox 9 function promotes heart valve calcification phenotypes in vivo
-
Peacock J. Levay A. Gillaspie D. Tao G. Lincoln J. (2010) Reduced Sox 9 function promotes heart valve calcification phenotypes in vivo. Circ Res 106: 712–719.
-
(2010)
Circ Res
, vol.106
, pp. 712-719
-
-
Peacock, J.1
Levay, A.2
Gillaspie, D.3
Tao, G.4
Lincoln, J.5
-
33
-
-
80053332467
-
New evidence for a critical role of elastin in calcification of native heart valves: immunohistochemical and ultrastructural study with literature review
-
Perrotta I. Russo E. Camastra C. Filice G. Mizio G. Colosimo F. et al. (2011) New evidence for a critical role of elastin in calcification of native heart valves: immunohistochemical and ultrastructural study with literature review. Histopathology 59: 504–513.
-
(2011)
Histopathology
, vol.59
, pp. 504-513
-
-
Perrotta, I.1
Russo, E.2
Camastra, C.3
Filice, G.4
Mizio, G.5
Colosimo, F.6
-
34
-
-
59449092756
-
Calcific aortic stenosis: lessons learned from experimental and clinical studies
-
Rajamannan N.M. (2009) Calcific aortic stenosis: lessons learned from experimental and clinical studies. Arterioscler Thromb Vasc Biol 29: 162–168.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 162-168
-
-
Rajamannan, N.M.1
-
35
-
-
73549103784
-
Mechanisms of aortic valve calcification: the LDL-density-radius theory: a translation from cell signaling to physiology
-
Rajamannan N.M. (2010) Mechanisms of aortic valve calcification: the LDL-density-radius theory: a translation from cell signaling to physiology. Am J Physiol Heart Circ Physiol 298: H5-H15.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
, pp. H5-H15
-
-
Rajamannan, N.M.1
-
36
-
-
84860390043
-
The role of Lrp5/6 in cardiac valve disease: LDL-density-pressure theory
-
Rajamannan N.M. (2011) The role of Lrp5/6 in cardiac valve disease: LDL-density-pressure theory. J Cell Biochem 112: 2222–2229.
-
(2011)
J Cell Biochem
, vol.112
, pp. 2222-2229
-
-
Rajamannan, N.M.1
-
37
-
-
24644510707
-
Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp 5 receptor pathway
-
Rajamannan N.M. Subramaniam M. Caira F. Stock S.R. Spelsberg T.C. (2005) Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp 5 receptor pathway. Circulation 112: I-229–I-234.
-
(2005)
Circulation
, vol.112
, pp. I-229-I-234
-
-
Rajamannan, N.M.1
Subramaniam, M.2
Caira, F.3
Stock, S.R.4
Spelsberg, T.C.5
-
38
-
-
40949136592
-
Clinical Review: Degenerative aortic stenosis
-
Ramaraj R. Sorrell V.L. (2008) Clinical Review: Degenerative aortic stenosis. BMJ 336: 550–555.
-
(2008)
BMJ
, vol.336
, pp. 550-555
-
-
Ramaraj, R.1
Sorrell, V.L.2
-
40
-
-
22144465811
-
Cardiac valves and valvular pathology: update on function, disease, repair, and replacement
-
Schoen F.J. (2005) Cardiac valves and valvular pathology: update on function, disease, repair, and replacement. Cardiovasc Pathol 14: 189–194.
-
(2005)
Cardiovasc Pathol
, vol.14
, pp. 189-194
-
-
Schoen, F.J.1
-
41
-
-
0041386133
-
Angiogenesis is involved in the pathogenesis of nonrheumatic aortic valve stenosis
-
Soini Y. Salo T. Satta J. (2003) Angiogenesis is involved in the pathogenesis of nonrheumatic aortic valve stenosis. Hum Pathol 34: 756–763.
-
(2003)
Hum Pathol
, vol.34
, pp. 756-763
-
-
Soini, Y.1
Salo, T.2
Satta, J.3
-
42
-
-
66749144633
-
Drug delivery at the aortic valve tissues of healthy domestic pigs with a paclitaxel-eluting valvuloplasty balloon
-
Spargias K. Milewski K. Debinski M. Buszman P. Cokkinos D. Pogge R. et al. (2009) Drug delivery at the aortic valve tissues of healthy domestic pigs with a paclitaxel-eluting valvuloplasty balloon. J Intervent Cardiol 22: 291–298.
-
(2009)
J Intervent Cardiol
, vol.22
, pp. 291-298
-
-
Spargias, K.1
Milewski, K.2
Debinski, M.3
Buszman, P.4
Cokkinos, D.5
Pogge, R.6
-
43
-
-
0029335801
-
Inhibition of angiotensin-converting enzyme and attenuation of myocardial fibrosis by lisinopril in rats receiving angiotensin II
-
Sun Y.A.O. Ratajska A. Weber K.T. (1995) Inhibition of angiotensin-converting enzyme and attenuation of myocardial fibrosis by lisinopril in rats receiving angiotensin II. J Lab Clin Med 126: 95–101.
-
(1995)
J Lab Clin Med
, vol.126
, pp. 95-101
-
-
Sun, Y.A.O.1
Ratajska, A.2
Weber, K.T.3
-
45
-
-
49349083037
-
In vivo aortic valve thermal heterogeneity in patients with nonrheumatic aortic valve stenosis. The first in vivo experience in humans
-
Toutouzas K. Drakopoulou M. Synetos A. Tsiamis E. Agrogiannis G. Kavantzas N. et al. (2008) In vivo aortic valve thermal heterogeneity in patients with nonrheumatic aortic valve stenosis. The first in vivo experience in humans. J Am Coll Cardiol 52:758–763.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 758-763
-
-
Toutouzas, K.1
Drakopoulou, M.2
Synetos, A.3
Tsiamis, E.4
Agrogiannis, G.5
Kavantzas, N.6
-
47
-
-
54049117251
-
Detection and quantification of angiogenesis in experimental valve disease with integrin-targeted nanoparticles and 19-fluorine MRI/MRS
-
Waters E. Chen J. Allen J. Zhang H. Lanza G. Wickline S. (2008) Detection and quantification of angiogenesis in experimental valve disease with integrin-targeted nanoparticles and 19-fluorine MRI/MRS. J Cardiovasc Magn Reson 10: 43.
-
(2008)
J Cardiovasc Magn Reson
, vol.10
, pp. 43
-
-
Waters, E.1
Chen, J.2
Allen, J.3
Zhang, H.4
Lanza, G.5
Wickline, S.6
-
48
-
-
77956310581
-
Common pathogenic features of atherosclerosis and calcific aortic stenosis: role of transforming growth factor-[beta]
-
Xu S. Liu A.C. Gotlieb A.I. (2010) Common pathogenic features of atherosclerosis and calcific aortic stenosis: role of transforming growth factor-[beta]. Cardiovasc Pathol 19: 236–247.
-
(2010)
Cardiovasc Pathol
, vol.19
, pp. 236-247
-
-
Xu, S.1
Liu, A.C.2
Gotlieb, A.I.3
-
49
-
-
58949103283
-
Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2
-
Yang X. Fullerton D.A. Su X. Ao L. Cleveland J.C. Jr Meng X. (2009) Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2. J Am Coll Cardiol 53: 491–500.
-
(2009)
J Am Coll Cardiol
, vol.53
, pp. 491-500
-
-
Yang, X.1
Fullerton, D.A.2
Su, X.3
Ao, L.4
Cleveland, J.C.5
Meng, X.6
-
50
-
-
67349191480
-
Molecular and cellular mechanisms of aortic stenosis
-
Yetkin E. Waltenberger J. (2009) Molecular and cellular mechanisms of aortic stenosis. Int J Cardiol 135: 4–13.
-
(2009)
Int J Cardiol
, vol.135
, pp. 4-13
-
-
Yetkin, E.1
Waltenberger, J.2
|