Detection and quantification of angiogenesis in experimental valve disease with integrin-targeted nanoparticles and 19-fluorine MRI/MRS

Journal of Cardiovascular Magnetic Resonance

Volumn 10, Issue 1, 2008, Pages

  Waters, Emily A ^a,b   Chen, Junjie ^a   Allen, John S ^a   Zhang, Huiying ^a   Lanza, Gregory M ^a   Wickline, Samuel A ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CONTRAST MEDIUM; FLUORINE; FLUOROCARBON; NANOPARTICLE; OIL; VITRONECTIN RECEPTOR;

ANALYSIS OF VARIANCE; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA VALVE DISEASE; ARTICLE; ATHEROSCLEROSIS; CARDITIS; CHOLESTEROL DIET; CHOLESTEROL INTAKE; COMPARATIVE STUDY; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENDOTHELIUM; EXCISION; EXPERIMENTAL STUDY; FLUORINE NUCLEAR MAGNETIC RESONANCE; HEART VALVE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MEDICAL INSTRUMENTATION; NEW ZEALAND; NONHUMAN; POST HOC ANALYSIS; PRIORITY JOURNAL; RABBIT; SAMPLE; SPECTROSCOPY; STAINING; STUDENT T TEST; THERAPY EFFECT; VASCULARIZATION; ANIMAL; AORTA VALVE; AORTA VALVE STENOSIS; BINDING COMPETITION; BINDING SITE; DISEASE MODEL; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; SCLEROSIS; UPREGULATION;

ANIMALS; AORTIC VALVE; AORTIC VALVE STENOSIS; BINDING SITES; BINDING, COMPETITIVE; DISEASE MODELS, ANIMAL; FLUORINE; FLUOROCARBONS; IMMUNOHISTOCHEMISTRY; INTEGRIN ALPHAVBETA3; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; NEOVASCULARIZATION, PATHOLOGIC; RABBITS; SCLEROSIS; UP-REGULATION;

EID: 54049117251     PISSN: 10976647     EISSN: 1532429X     Source Type: Journal    
DOI: 10.1186/1532-429X-10-43     Document Type: Article

References (29)

1. Stewart BF, Siscovik DS, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM: Clinical factors associated with calcific aortic disease. Journal of the American College of Cardiology 1997, 29: 630-634. (Pubitemid 27116107)
2. Otto CM, Lind BK, Kitzman DW, Gersh BJ, Siscovick DS: Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med 1999, 341: 142.
3. Hara H, Pedersen WR, Ladich E, Mooney M, Virmani R, Nakamura M, Feldman T, Schwartz RS: Percutaneous Balloon Aortic Valvuloplasty Revisited: Time for a Renaissance? Circulation 2007, 115: e334-338. (Pubitemid 46648656)
4. Otto CM, Kuusisto J, Reichenbach DD, Gown AM, O'Brien KD: Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies. Circulation 1994, 90: 844-853. (Pubitemid 24242754)
5. Moura LM, Ramos SF, Zamorano JL, Barros IM, Azevedo LF, Rocha- Goncalves F, Rajamannan NM: Rosuvastatin Affecting Aortic Valve Endothelium to Slow the Progression of Aortic Stenosis. Journal of the American College of Cardiology 2007, 49: 554-561. (Pubitemid 46177435)
6. Chalajour F, Treede H, Ebrahimnejad A, Lauke H, Reichenspurner H, Ergun S: Angiogenic Activation of Valvular Endothelial Cells in Aortic Valve Stenosis. Experimental Cell Research 2004, 298: 455-464. (Pubitemid 38950862)
7. Charest A, Pepin A, Shetty R, Cote C, Voisine P, Dagenais F, Pibarot P, Mathieu P: Distribution of SPARC During Neovascularization of Degenerative Aortic Stenosis. Heart 2006, 92(12): 1844-1849. (Pubitemid 44851338)
8. Mazzone A, Epistolato MC, DeCaterina R, Storti S, Vittorini S, Sbrana S, Gianetti J, Bevilacqua S, Glauber M, Biagini A, Tanganelli P: Neoangiogenesis, T-lymphocyte infiltration, and heat shock protein- 60 are biological hallmarks of an immunomediated inflammatory process in end-stage calcified aortic valve stenosis. Journal of the American College of Cardiology 2004, 43: 1670-1676. (Pubitemid 38561351)
9. Soini Y, Salo T, Satta J: Angiogenesis is involved in the pathogenesis of nonrheumatic aortic valve stenosis. Hum Pathol 2003, 34: 756-763. (Pubitemid 37040610)
10. Kamimura R, Suzuki S, Sakamoto H, Miura N, Misumi K, Miyahara K: Development of Atherosclerotic Lesions in Cholesterolloaded Rabbits. Experimental Animals 1999, 48: 1-7. (Pubitemid 129565740)
11. Rajamannan NM, Subramaniam M, Springett M, Sebo TC, Niekrasz M, McConnell JP, Singh RJ, Stone NJ, Bonow RO, Spelsberg TC: Atorvastatin Inhibits Hypercholesteremia-Induced Cellular Proliferation and Bone Matrix Production in the Rabbit Aortic Valve. Circulation 2002, 105: 2660-2665. (Pubitemid 34596044)
12. Drolet MC, Arsenault M, Couet J: Experimental Aortic Valve Stenosis in Rabbits. Journal of the American College of Cardiology 2003, 41: 1211-1217. (Pubitemid 36384911)
13. Kwon HM, Lee BK, Kim D, Hong BK, Byun KH, Kna JS, Kim IJ, Oh SH, Kim H-S: Experimental Hypercholesteremia Induces Ultrastructural Changes in the Elastic Laminae of Rabbit Aortic Valve. Yonsei Medical Journal 1998, 39: 345-354. (Pubitemid 128506892)
14. Cimini M, Boughner DR, Ronald JA, Aldington L, Rogers KA: Development of Aortic Valve Sclerosis in a Rabbit Model of Atherosclerosis: An Immunohistochemical and Histological Study. Journal of Heart Valve Disease 2005, 14: 365-375. (Pubitemid 47050751)
15. Winter PM, Morawski AM, Caruthers SD, Fuhrhop RW, Zhang H, Williams TA, Allen JS, Lacy EK, Robertson JD, Lanza GM, Wickline SA: Molecular Imaging of Angiogenesis in Early-Stage Atherosclerosis With avb3-Integrin-Targeted Nanoparticles. Circulation 2003, 108: 2270-2274.
16. Morawski AM, Winter PM, Yu X, Fuhrhop RW, Scott MJ, Hockett F, Robertson JD, Gaffney PJ, Lanza GM, Wickline SA: Quantitative "magnetic resonance immunohistochemistry" with ligandtargeted 19F nanoparticles. Magnetic Resonance in Medicine 2004, 52: 1255-1262. (Pubitemid 39612813)
17. Caruthers SD, Neubauer AM, Hockett FD, Lamerichs R, Winter PM, Scott MJ, Gaffney PJ, Wickline SA, Lanza GM: In Vitro Demonstration Using 19F Magnetic Resonance to Augment Molecular Imaging With Paramagnetic Perfluorocarbon Nanoparticles at 1.5 Tesla. Investigative Radiology 2006, 41: 305-312. (Pubitemid 44406192)
18. Wickline SA, Neubauer AM, Winter PM, Caruthers SD, Lanza GM: Applications of Nanotechnology to Atherosclerosis, Thrombosis, and Vascular Biology. Arteriosclerosis, Thrombosis, and Vascular Biology 2005, 26: .
19. Caira FC, Stock SR, Gleason TG, McGee EC, Huang J, Bonow RO, Spelsberg TC, McCarthy PM, Rahimtoola SH, Rajamannan NM: Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation. Journal of the American College of Cardiology 2006, 47: 1707-1712.
20. Lanza GM, Wallace KD, Scott MJ, Cacheris WP, Abendschein DR, Christy DH, Sharkey AM, Miller JG, Gaffney PJ, Wickline SA: A Novel Site-Targeted Ultrasonic Contrast Agent With Broad Biomedical Application. Circulation 1996, 94: 3334-3340.
21. Mofidi R, Crotty TB, McCarthy PM, Sheehan SJ, Mehigan D, Keaveny TV: Association between plaque instability, angiogenesis, and symptomatic carotid occlusive disease. British Journal of Surgery 2001, 88: 945-950. (Pubitemid 34015576)
22. Virmani R, Kolodgie FD, Burke AP, Finn AV, Gold HK, Tulenko TN, Wrenn SP, Narula J: Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arteriosclerosis, Thrombosis, and Vascular Biology 2005, 25: 2054. (Pubitemid 41416300)
23. Folkman J: Angiogenesis. Annual Review of Medicine 2006, 57: 1-18. (Pubitemid 43261975)
24. Sadeghi MM, Krassilnikova S, Zhang J, Gharaei AA, Fassaei HR, Esmailzadeh L, Kooshkabadi A, Edwards S, Yalamanchili P, Harris TD, et al.: Detection of Injury-Induced Vascular Remodeling by Targeting Activated {alpha}v{beta}3 Integrin In Vivo. Circulation 2004, 110: 84-90. (Pubitemid 38880138)
25. Hu G, Lijowski M, Zhang H, Partlow KC, Caruthers SD, Kiefer G, Gulyas G, Athey P, Scott MJ, Wickline SA, Lanza GM: Imaging of Vx- 2 rabbit tumors with avb3-integrin-targeted 111-In nanoparticles. Int J Cancer 2007, 120: 1951-1957.
26. Morawski AM, Winter PM, Crowder KC, Caruthers SD, Fuhrhop RJ, Scott MJ, Robertson D, Abendschein DR, Lanza GM, Wickline SA: Targeted nanoparticles for quantitative imaging of sparse molecular epitopes with MRI. Magn Reson Med 2004, 51: 480-486.
27. Edep ME, Shirani J, Wolf P, Brown DL: Matrix Metalloproteinase Expression in Nonrheumatic Aortic Stenosis. Cardiovascular Pathology 2000, 9: 281-286. (Pubitemid 30813377)
28. Partlow KC, Chen J, Brant JA, Neubauer AM, Meyerrose TE, Creer MH, Nolta JA, Caruthers SD, Lanza GM, Wickline SA: 19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons. FASEB Journal 2007, 21: 1647. (Pubitemid 46855610)
29. Moulton KS, Heller E, Konerding MA, Flynn E, Palinski W, Folkman J: Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein- E deficient mice. Circulation 1999, 99: 1726-1732. (Pubitemid 29162486)