Hyperadiponectinemia protects against premature death in metabolic syndrome model mice by inhibiting AKT signaling and chronic inflammation

Journal of Endocrinology

Volumn 213, Issue 1, 2012, Pages 67-76

  Otabe, S ^a   Wada, N ^a   Hashinaga, T ^a   Yuan, X ^a   Shimokawa, I ^b   Fukutani, T ^a   Tanaka, K ^a   Ohki, T ^a   Kakino, S ^a   Kurita, Y ^a   Nakayama, H ^a   Tajiri, Y ^a   Yamada, K ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; C REACTIVE PROTEIN; INSULIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA; ADIPOQ PROTEIN, HUMAN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; BODY WEIGHT; CHRONIC INFLAMMATION; CONTROLLED STUDY; DEATH; DISORDERS OF HORMONE METABOLISM; ENZYME INHIBITION; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HYPERADIPONECTINEMIA; INSULIN BLOOD LEVEL; INSULIN TOLERANCE TEST; LIFESPAN; LIVER; LONGEVITY; MALE; METABOLIC SYNDROME X; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BLOOD; C57BL MOUSE; CHRONIC DISEASE; COMPARATIVE STUDY; DISEASE MODEL; DRUG ANTAGONISM; GENETICS; HUMAN; INFLAMMATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; PREMATURE MORTALITY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADIPONECTIN; ANIMALS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATION; MALE; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MORTALITY, PREMATURE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84860798761     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-11-0329     Document Type: Article

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