메뉴 건너뛰기




Volumn 26, Issue 5, 2012, Pages 1053-1063

Characterization of intratumoral follicular helper T cells in follicular lymphoma: Role in the survival of malignant B cells

Author keywords

follicular helper T cells; Follicular lymphoma; follicular regulatory T cells

Indexed keywords

CD40 LIGAND; CHEMOKINE RECEPTOR CXCR5; GAMMA INTERFERON; INTERLEUKIN 4; RITUXIMAB;

EID: 84860747727     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.301     Document Type: Article
Times cited : (146)

References (51)
  • 1
    • 0036884169 scopus 로고    scopus 로고
    • Lymphoid malignancies: The dark side of B-cell differentiation
    • Shaffer AL, Rosenwald A, Staudt LM. Lymphoid malignancies: the dark side of B-cell differentiation. Nat Rev Immunol 2002; 2: 920-932.
    • (2002) Nat Rev Immunol , vol.2 , pp. 920-932
    • Shaffer, A.L.1    Rosenwald, A.2    Staudt, L.M.3
  • 2
    • 0038646049 scopus 로고    scopus 로고
    • Phenotypic modulation of the stromal reticular network in normal and neoplastic lymph nodes: Tissue transglutaminase reveals coordinate regulation of multiple cell types
    • Thomazy VA, Vega F, Medeiros LJ, Davies PJ, Jones D. Phenotypic modulation of the stromal reticular network in normal and neoplastic lymph nodes: tissue transglutaminase reveals coordinate regulation of multiple cell types. Am J Pathol 2003; 163: 165-174.
    • (2003) Am J Pathol , vol.163 , pp. 165-174
    • Thomazy, V.A.1    Vega, F.2    Medeiros, L.J.3    Davies, P.J.4    Jones, D.5
  • 3
    • 0028857781 scopus 로고
    • CD40 ligand is constitutively expressed in a subset of T cell lymphomas and on the microenvironmental reactive T cells of follicular lymphomas and Hodgkin's disease
    • Carbone A, Gloghini A, Gruss HJ, Pinto A. CD40 ligand is constitutively expressed in a subset of T cell lymphomas and on the microenvironmental reactive T cells of follicular lymphomas and Hodgkin's disease. Am J Pathol 1995; 147: 912-922.
    • (1995) Am J Pathol , vol.147 , pp. 912-922
    • Carbone, A.1    Gloghini, A.2    Gruss, H.J.3    Pinto, A.4
  • 4
    • 8644252736 scopus 로고    scopus 로고
    • Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells
    • Dave SS, Wright G, Tan B, Rosenwald A, Gascoyne RD, Chan WC et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N Engl J Med 2004; 351: 2159-2169.
    • (2004) N Engl J Med , vol.351 , pp. 2159-2169
    • Dave, S.S.1    Wright, G.2    Tan, B.3    Rosenwald, A.4    Gascoyne, R.D.5    Chan, W.C.6
  • 5
    • 33846974737 scopus 로고    scopus 로고
    • Gene-expression and immunohistochemical study of specific T-cell subsets and accessory cell types in the transformation and prognosis of follicular lymphoma
    • Glas AM, Knoops L, Delahaye L, Kersten MJ, Kibbelaar RE, Wessels LA et al. Gene-expression and immunohistochemical study of specific T-cell subsets and accessory cell types in the transformation and prognosis of follicular lymphoma. J Clin Oncol 2007; 25: 390-398.
    • (2007) J Clin Oncol , vol.25 , pp. 390-398
    • Glas, A.M.1    Knoops, L.2    Delahaye, L.3    Kersten, M.J.4    Kibbelaar, R.E.5    Wessels, L.A.6
  • 6
    • 33751194652 scopus 로고    scopus 로고
    • High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma
    • Carreras J, Lopez-Guillermo A, Fox BC, Colomo L, Martinez A, Roncador G et al. High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma. Blood 2006; 108: 2957-2964.
    • (2006) Blood , vol.108 , pp. 2957-2964
    • Carreras, J.1    Lopez-Guillermo, A.2    Fox, B.C.3    Colomo, L.4    Martinez, A.5    Roncador, G.6
  • 7
    • 75649101327 scopus 로고    scopus 로고
    • The architectural pattern of FOXP3-positive T cells in follicular lymphoma is an independent predictor of survival and histologic transformation
    • Farinha P, Al-Tourah A, Gill K, Klasa R, Connors JM, Gascoyne RD. The architectural pattern of FOXP3-positive T cells in follicular lymphoma is an independent predictor of survival and histologic transformation. Blood 2010; 115: 289-295.
    • (2010) Blood , vol.115 , pp. 289-295
    • Farinha, P.1    Al-Tourah, A.2    Gill, K.3    Klasa, R.4    Connors, J.M.5    Gascoyne, R.D.6
  • 8
    • 80052623454 scopus 로고    scopus 로고
    • Soluble IL-2R{alpha} facilitates IL-2-mediated immune responses and predicts reduced survival in follicular B-cell non-Hodgkin lymphoma
    • Yang ZZ, Grote DM, Ziesmer SC, Manske MK, Witzig TE, Novak AJ et al. Soluble IL-2R{alpha} facilitates IL-2-mediated immune responses and predicts reduced survival in follicular B-cell non-Hodgkin lymphoma. Blood 2011; 118: 2809-2820.
    • (2011) Blood , vol.118 , pp. 2809-2820
    • Yang, Z.Z.1    Grote, D.M.2    Ziesmer, S.C.3    Manske, M.K.4    Witzig, T.E.5    Novak, A.J.6
  • 9
    • 33646422454 scopus 로고    scopus 로고
    • Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma
    • Yang ZZ, Novak AJ, Stenson MJ, Witzig TE, Ansell SM. Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma. Blood 2006; 107: 3639-3646.
    • (2006) Blood , vol.107 , pp. 3639-3646
    • Yang, Z.Z.1    Novak, A.J.2    Stenson, M.J.3    Witzig, T.E.4    Ansell, S.M.5
  • 10
    • 33750535641 scopus 로고    scopus 로고
    • Attenuation of CD8(+) T-cell function by CD4(+)CD25(+) regulatory T cells in B-cell non-Hodgkin's lymphoma
    • Yang ZZ, Novak AJ, Ziesmer SC, Witzig TE, Ansell SM. Attenuation of CD8(+) T-cell function by CD4(+)CD25(+) regulatory T cells in B-cell non-Hodgkin's lymphoma. Cancer Res 2006; 66: 10145-10152.
    • (2006) Cancer Res , vol.66 , pp. 10145-10152
    • Yang, Z.Z.1    Novak, A.J.2    Ziesmer, S.C.3    Witzig, T.E.4    Ansell, S.M.5
  • 11
    • 34247190110 scopus 로고    scopus 로고
    • Immunohistochemical patterns of reactive microenvironment are associated with clinicobiologic behavior in follicular lymphoma patients
    • Alvaro T, Lejeune M, Salvado MT, Lopez C, Jaen J, Bosch R et al. Immunohistochemical patterns of reactive microenvironment are associated with clinicobiologic behavior in follicular lymphoma patients. J Clin Oncol 2006; 24: 5350-5357.
    • (2006) J Clin Oncol , vol.24 , pp. 5350-5357
    • Alvaro, T.1    Lejeune, M.2    Salvado, M.T.3    Lopez, C.4    Jaen, J.5    Bosch, R.6
  • 12
    • 63049113299 scopus 로고    scopus 로고
    • High numbers of tumor-infiltrating programmed cell death 1-positive regulatory lymphocytes are associated with improved overall survival in follicular lymphoma
    • Carreras J, Lopez-Guillermo A, Roncador G, Villamor N, Colomo L, Martinez A et al. High numbers of tumor-infiltrating programmed cell death 1-positive regulatory lymphocytes are associated with improved overall survival in follicular lymphoma. J Clin Oncol 2009; 27: 1470-1476.
    • (2009) J Clin Oncol , vol.27 , pp. 1470-1476
    • Carreras, J.1    Lopez-Guillermo, A.2    Roncador, G.3    Villamor, N.4    Colomo, L.5    Martinez, A.6
  • 13
    • 79952984773 scopus 로고    scopus 로고
    • Follicular programmed death 1-positive lymphocytes in the tumor microenvironment are an independent prognostic factor in follicular lymphoma
    • Richendollar BG, Pohlman B, Elson P, Hsi ED. Follicular programmed death 1-positive lymphocytes in the tumor microenvironment are an independent prognostic factor in follicular lymphoma. Hum Pathol 2011; 42: 552-557.
    • (2011) Hum Pathol , vol.42 , pp. 552-557
    • Richendollar, B.G.1    Pohlman, B.2    Elson, P.3    Hsi, E.D.4
  • 14
    • 79952675131 scopus 로고    scopus 로고
    • Follicular Helper CD4T Cells (T(FH))
    • Crotty S. Follicular Helper CD4T Cells (T(FH)). Annu Rev Immunol 2011; 29: 621-663.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 15
    • 69249109601 scopus 로고    scopus 로고
    • Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
    • Johnston RJ, Poholek AC, DiToro D, Yusuf I, Eto D, Barnett B et al. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 2009; 325: 1006-1010.
    • (2009) Science , vol.325 , pp. 1006-1010
    • Johnston, R.J.1    Poholek, A.C.2    Ditoro, D.3    Yusuf, I.4    Eto, D.5    Barnett, B.6
  • 16
    • 70450265288 scopus 로고    scopus 로고
    • Early commitment of naive human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12
    • Ma CS, Suryani S, Avery DT, Chan A, Nanan R, Santner-Nanan B et al. Early commitment of naive human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12. Immunol Cell Biol 2009; 87: 590-600.
    • (2009) Immunol Cell Biol , vol.87 , pp. 590-600
    • Ma, C.S.1    Suryani, S.2    Avery, D.T.3    Chan, A.4    Nanan, R.5    Santner-Nanan, B.6
  • 17
    • 78650309840 scopus 로고    scopus 로고
    • Follicular lymphoma cell niche: Identification of a preeminent IL-4-dependent T(FH)-B cell axis
    • Pangault C, Ame-Thomas P, Ruminy P, Rossille D, Caron G, Baia M et al. Follicular lymphoma cell niche: identification of a preeminent IL-4-dependent T(FH)-B cell axis. Leukemia 2010; 24: 2080-2089.
    • (2010) Leukemia , vol.24 , pp. 2080-2089
    • Pangault, C.1    Ame-Thomas, P.2    Ruminy, P.3    Rossille, D.4    Caron, G.5    Baia, M.6
  • 18
    • 58449124804 scopus 로고    scopus 로고
    • The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
    • Bauquet AT, Jin H, Paterson AM, Mitsdoerffer M, Ho IC, Sharpe AH et al. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol 2009; 10: 167-175.
    • (2009) Nat Immunol , vol.10 , pp. 167-175
    • Bauquet, A.T.1    Jin, H.2    Paterson, A.M.3    Mitsdoerffer, M.4    Ho, I.C.5    Sharpe, A.H.6
  • 19
    • 23444434705 scopus 로고    scopus 로고
    • The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo
    • Akiba H, Takeda K, Kojima Y, Usui Y, Harada N, Yamazaki T et al. The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo. J Immunol 2005; 175: 2340-2348.
    • (2005) J Immunol , vol.175 , pp. 2340-2348
    • Akiba, H.1    Takeda, K.2    Kojima, Y.3    Usui, Y.4    Harada, N.5    Yamazaki, T.6
  • 20
    • 33746256850 scopus 로고    scopus 로고
    • Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4T cells and is independent of CD57 expression
    • Rasheed AU, Rahn HP, Sallusto F, Lipp M, Muller G. Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4T cells and is independent of CD57 expression. Eur J Immunol 2006; 36: 1892-1903.
    • (2006) Eur J Immunol , vol.36 , pp. 1892-1903
    • Rasheed, A.U.1    Rahn, H.P.2    Sallusto, F.3    Lipp, M.4    Muller, G.5
  • 21
    • 34247149460 scopus 로고    scopus 로고
    • Germinal center helper T cells are dual functional regulatory cells with suppressive activity to conventional CD4+ T cells
    • Marinova E, Han S, Zheng B. Germinal center helper T cells are dual functional regulatory cells with suppressive activity to conventional CD4+ T cells. J Immunol 2007; 178: 5010-5017.
    • (2007) J Immunol , vol.178 , pp. 5010-5017
    • Marinova, E.1    Han, S.2    Zheng, B.3
  • 22
    • 44649189089 scopus 로고    scopus 로고
    • Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery
    • Ito T, Hanabuchi S, Wang YH, Park WR, Arima K, Bover L et al. Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery. Immunity 2008; 28: 870-880.
    • (2008) Immunity , vol.28 , pp. 870-880
    • Ito, T.1    Hanabuchi, S.2    Wang, Y.H.3    Park, W.R.4    Arima, K.5    Bover, L.6
  • 23
    • 66149099328 scopus 로고    scopus 로고
    • Functional alteration of the lymphoma stromal cell niche by the cytokine context: Role of indoleamine-2,3 dioxygenase
    • Maby-El Hajjami H, Ame-Thomas P, Pangault C, Tribut O, DeVos J, Jean R et al. Functional alteration of the lymphoma stromal cell niche by the cytokine context: role of indoleamine-2,3 dioxygenase. Cancer Res 2009; 69: 3228-3237.
    • (2009) Cancer Res , vol.69 , pp. 3228-3237
    • Maby-El Hajjami, H.1    Ame-Thomas, P.2    Pangault, C.3    Tribut, O.4    Devos, J.5    Jean, R.6
  • 24
    • 47249125726 scopus 로고    scopus 로고
    • Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes
    • Pene J, Chevalier S, Preisser L, Venereau E, Guilleux MH, Ghannam S et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J Immunol 2008; 180: 7423-7430.
    • (2008) J Immunol , vol.180 , pp. 7423-7430
    • Pene, J.1    Chevalier, S.2    Preisser, L.3    Venereau, E.4    Guilleux, M.H.5    Ghannam, S.6
  • 25
    • 0035577641 scopus 로고    scopus 로고
    • Identification and validation of endogenous reference genes for expression profiling of T helper cell differentiation by quantitative real-time RT-PCR
    • Hamalainen HK, Tubman JC, Vikman S, Kyrola T, Ylikoski E, Warrington JA et al. Identification and validation of endogenous reference genes for expression profiling of T helper cell differentiation by quantitative real-time RT-PCR. Anal Biochem 2001; 299: 63-70.
    • (2001) Anal Biochem , vol.299 , pp. 63-70
    • Hamalainen, H.K.1    Tubman, J.C.2    Vikman, S.3    Kyrola, T.4    Ylikoski, E.5    Warrington, J.A.6
  • 27
    • 0021253159 scopus 로고
    • Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones
    • Yssel H, De Vries JE, Koken M, Van Blitterswijk W, Spits H. Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones. J Immunol Methods 1984; 72: 219-227.
    • (1984) J Immunol Methods , vol.72 , pp. 219-227
    • Yssel, H.1    De Vries, J.E.2    Koken, M.3    Van Blitterswijk, W.4    Spits, H.5
  • 28
    • 77955924180 scopus 로고    scopus 로고
    • Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling
    • Deenick EK, Chan A, Ma CS, Gatto D, Schwartzberg PL, Brink R et al. Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling. Immunity 2010; 33: 241-253.
    • (2010) Immunity , vol.33 , pp. 241-253
    • Deenick, E.K.1    Chan, A.2    Ma, C.S.3    Gatto, D.4    Schwartzberg, P.L.5    Brink, R.6
  • 29
    • 62849090439 scopus 로고    scopus 로고
    • Cytokine-secreting follicular T cells shape the antibody repertoire
    • Reinhardt RL, Liang HE, Locksley RM. Cytokine-secreting follicular T cells shape the antibody repertoire. Nat Immunol 2009; 10: 385-393.
    • (2009) Nat Immunol , vol.10 , pp. 385-393
    • Reinhardt, R.L.1    Liang, H.E.2    Locksley, R.M.3
  • 30
    • 0037306893 scopus 로고    scopus 로고
    • In vitro mechanisms of action of rituximab on primary non-Hodgkin lymphomas
    • Manches O, Lui G, Chaperot L, Gressin R, Molens JP, Jacob MC et al. In vitro mechanisms of action of rituximab on primary non-Hodgkin lymphomas. Blood 2003; 101: 949-954.
    • (2003) Blood , vol.101 , pp. 949-954
    • Manches, O.1    Lui, G.2    Chaperot, L.3    Gressin, R.4    Molens, J.P.5    Jacob, M.C.6
  • 31
    • 20144382754 scopus 로고    scopus 로고
    • Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
    • Monti S, Savage KJ, Kutok JL, Feuerhake F, Kurtin P, Mihm M et al. Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response. Blood 2005; 105: 1851-1861.
    • (2005) Blood , vol.105 , pp. 1851-1861
    • Monti, S.1    Savage, K.J.2    Kutok, J.L.3    Feuerhake, F.4    Kurtin, P.5    Mihm, M.6
  • 32
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000; 403: 503-511.
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3    Ma, C.4    Lossos, I.S.5    Rosenwald, A.6
  • 33
    • 77955357487 scopus 로고    scopus 로고
    • Predicting transformation in follicular lymphoma
    • de Jong D, de Boer JP. Predicting transformation in follicular lymphoma. Leuk Lymphoma 2009; 50: 1406-1411.
    • (2009) Leuk Lymphoma , vol.50 , pp. 1406-1411
    • De Jong, D.1    De Boer, J.P.2
  • 34
    • 49149125958 scopus 로고    scopus 로고
    • Expression of ICOS on human melanoma-infiltrating CD4+CD25highFoxp3+ T regulatory cells: Implications and impact on tumor-mediated immune suppression
    • Strauss L, Bergmann C, Szczepanski MJ, Lang S, Kirkwood JM, Whiteside TL. Expression of ICOS on human melanoma-infiltrating CD4+CD25highFoxp3+ T regulatory cells: implications and impact on tumor-mediated immune suppression. J Immunol 2008; 180: 2967-2980.
    • (2008) J Immunol , vol.180 , pp. 2967-2980
    • Strauss, L.1    Bergmann, C.2    Szczepanski, M.J.3    Lang, S.4    Kirkwood, J.M.5    Whiteside, T.L.6
  • 35
    • 34948875291 scopus 로고    scopus 로고
    • CD70+ non-Hodgkin lymphoma B cells induce Foxp3 expression and regulatory function in intratumoral CD4+CD25T cells
    • Yang ZZ, Novak AJ, Ziesmer SC, Witzig TE, Ansell SM. CD70+ non-Hodgkin lymphoma B cells induce Foxp3 expression and regulatory function in intratumoral CD4+CD25T cells. Blood 2007; 110: 2537-2544.
    • (2007) Blood , vol.110 , pp. 2537-2544
    • Yang, Z.Z.1    Novak, A.J.2    Ziesmer, S.C.3    Witzig, T.E.4    Ansell, S.M.5
  • 36
    • 67650446560 scopus 로고    scopus 로고
    • Malignant B cells skew the balance of regulatory T cells and TH17 cells in B-cell non-Hodgkin's lymphoma
    • Yang ZZ, Novak AJ, Ziesmer SC, Witzig TE, Ansell SM. Malignant B cells skew the balance of regulatory T cells and TH17 cells in B-cell non-Hodgkin's lymphoma. Cancer Res 2009; 69: 5522-5530.
    • (2009) Cancer Res , vol.69 , pp. 5522-5530
    • Yang, Z.Z.1    Novak, A.J.2    Ziesmer, S.C.3    Witzig, T.E.4    Ansell, S.M.5
  • 38
    • 79961158055 scopus 로고    scopus 로고
    • Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
    • Chung Y, Tanaka S, Chu F, Nurieva RI, Martinez GJ, Rawal S et al. Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat Med 2011; 17: 983-988.
    • (2011) Nat Med , vol.17 , pp. 983-988
    • Chung, Y.1    Tanaka, S.2    Chu, F.3    Nurieva, R.I.4    Martinez, G.J.5    Rawal, S.6
  • 39
    • 38049151375 scopus 로고    scopus 로고
    • Loss of IL-7 receptor alpha on CD4+ T cells defines terminally differentiated B cell-helping effector T cells in a B cell-rich lymphoid tissue
    • Lim HW, Kim CH. Loss of IL-7 receptor alpha on CD4+ T cells defines terminally differentiated B cell-helping effector T cells in a B cell-rich lymphoid tissue. J Immunol 2007; 179: 7448-7456.
    • (2007) J Immunol , vol.179 , pp. 7448-7456
    • Lim, H.W.1    Kim, C.H.2
  • 40
    • 33846255324 scopus 로고    scopus 로고
    • Human mesenchymal stem cells isolated from bone marrow and lymphoid organs support tumor B-cell growth: Role of stromal cells in follicular lymphoma pathogenesis
    • Ame-Thomas P, Maby-El Hajjami H, Monvoisin C, Jean R, Monnier D, Caulet-Maugendre S et al. Human mesenchymal stem cells isolated from bone marrow and lymphoid organs support tumor B-cell growth: role of stromal cells in follicular lymphoma pathogenesis. Blood 2007; 109: 693-702.
    • (2007) Blood , vol.109 , pp. 693-702
    • Ame-Thomas, P.1    Maby-El Hajjami, H.2    Monvoisin, C.3    Jean, R.4    Monnier, D.5    Caulet-Maugendre, S.6
  • 41
    • 46849111407 scopus 로고    scopus 로고
    • Clinical quantitation of immune signature in follicular lymphoma by RT-PCR-based gene expression profiling
    • Byers RJ, Sakhinia E, Joseph P, Glennie C, Hoyland JA, Menasce LP et al. Clinical quantitation of immune signature in follicular lymphoma by RT-PCR-based gene expression profiling. Blood 2008; 111: 4764-4770.
    • (2008) Blood , vol.111 , pp. 4764-4770
    • Byers, R.J.1    Sakhinia, E.2    Joseph, P.3    Glennie, C.4    Hoyland, J.A.5    Menasce, L.P.6
  • 42
    • 77954687601 scopus 로고    scopus 로고
    • Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment
    • Clear AJ, Lee AM, Calaminici M, Ramsay AG, Morris KJ, Hallam S et al. Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment. Blood 2010; 115: 5053-5056.
    • (2010) Blood , vol.115 , pp. 5053-5056
    • Clear, A.J.1    Lee, A.M.2    Calaminici, M.3    Ramsay, A.G.4    Morris, K.J.5    Hallam, S.6
  • 43
    • 77955859470 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells
    • Gandhi R, Kumar D, Burns EJ, Nadeau M, Dake B, Laroni A et al. Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells. Nat Immunol 2010; 11: 846-853.
    • (2010) Nat Immunol , vol.11 , pp. 846-853
    • Gandhi, R.1    Kumar, D.2    Burns, E.J.3    Nadeau, M.4    Dake, B.5    Laroni, A.6
  • 44
    • 42649095378 scopus 로고    scopus 로고
    • Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor
    • Quintana FJ, Basso AS, Iglesias AH, Korn T, Farez MF, Bettelli E et al. Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. Nature 2008; 453: 65-71.
    • (2008) Nature , vol.453 , pp. 65-71
    • Quintana, F.J.1    Basso, A.S.2    Iglesias, A.H.3    Korn, T.4    Farez, M.F.5    Bettelli, E.6
  • 45
    • 77956469491 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells
    • Ramirez JM, Brembilla NC, Sorg O, Chicheportiche R, Matthes T, Dayer JM et al. Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells. Eur J Immunol 2010; 40: 2450-2459.
    • (2010) Eur J Immunol , vol.40 , pp. 2450-2459
    • Ramirez, J.M.1    Brembilla, N.C.2    Sorg, O.3    Chicheportiche, R.4    Matthes, T.5    Dayer, J.M.6
  • 46
    • 77955903212 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27
    • Apetoh L, Quintana FJ, Pot C, Joller N, Xiao S, Kumar D et al. The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. Nat Immunol 2010; 11: 854-861.
    • (2010) Nat Immunol , vol.11 , pp. 854-861
    • Apetoh, L.1    Quintana, F.J.2    Pot, C.3    Joller, N.4    Xiao, S.5    Kumar, D.6
  • 48
    • 0037178853 scopus 로고    scopus 로고
    • Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL
    • Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ. Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. J Biol Chem 2002; 277: 27169-27175.
    • (2002) J Biol Chem , vol.277 , pp. 27169-27175
    • Wurster, A.L.1    Rodgers, V.L.2    White, M.F.3    Rothstein, T.L.4    Grusby, M.J.5
  • 49
    • 70350014904 scopus 로고    scopus 로고
    • Interleukin-4 distinctively modifies responses of germinal centre-like and activated B-cell-like diffuse large B-cell lymphomas to immuno-chemotherapy
    • Sarosiek KA, Nechushtan H, Lu X, Rosenblatt JD, Lossos IS. Interleukin-4 distinctively modifies responses of germinal centre-like and activated B-cell-like diffuse large B-cell lymphomas to immuno-chemotherapy. Br J Haematol 2009; 147: 308-318.
    • (2009) Br J Haematol , vol.147 , pp. 308-318
    • Sarosiek, K.A.1    Nechushtan, H.2    Lu, X.3    Rosenblatt, J.D.4    Lossos, I.S.5
  • 50
    • 0031401643 scopus 로고    scopus 로고
    • T-cell derived cytokines co-stimulate proliferation of CD40-activated germinal centre as well as follicular lymphoma cells
    • Schmitter D, Koss M, Niederer E, Stahel RA, Pichert G. T-cell derived cytokines co-stimulate proliferation of CD40-activated germinal centre as well as follicular lymphoma cells. Hematol Oncol 1997; 15: 197-207.
    • (1997) Hematol Oncol , vol.15 , pp. 197-207
    • Schmitter, D.1    Koss, M.2    Niederer, E.3    Stahel, R.A.4    Pichert, G.5
  • 51
    • 76149146398 scopus 로고    scopus 로고
    • IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
    • Gocheva V, Wang HW, Gadea BB, Shree T, Hunter KE, Garfall AL et al. IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes Dev 2010; 24: 241-255.
    • (2010) Genes Dev , vol.24 , pp. 241-255
    • Gocheva, V.1    Wang, H.W.2    Gadea, B.B.3    Shree, T.4    Hunter, K.E.5    Garfall, A.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.