Structural modifications of 99mTc-labelled bombesin-like peptides for optimizing pharmacokinetics in prostate tumor targeting

International Journal of Pharmaceutics

Volumn 430, Issue 1-2, 2012, Pages 1-17

  Liolios, Christos C ^a,b   Fragogeorgi, Eirini A ^a   Zikos, Christos ^a   Loudos, George ^c   Xanthopoulos, Stavros ^a   Bouziotis, Penelope ^a   Paravatou Petsotas, Maria ^a   Livaniou, Evangelia ^a   Varvarigou, Alexandra D ^a   Sivolapenko, Gregory B ^b  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b UNIVERSITY OF PATRAS   (Greece)

^c UNIVERSITY OF WEST ATTICA   (Greece)

Author keywords

99mTc; Bombesin; Pharmacokinetics; Scintigraphy; Tumor targeting

Indexed keywords

BOMBESIN DERIVATIVE; PERTECHNETIC ACID TC 99M; BOMBESIN; BOMBESIN RECEPTOR; DIAGNOSTIC AGENT; DRUG DERIVATIVE; LIGAND; PEPTIDE; RADIOPHARMACEUTICAL AGENT; TECHNETIUM;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; DRUG UPTAKE; FEMALE; HUMAN; HUMAN CELL; INTERNALIZATION; ISOTOPE LABELING; MOUSE; NONHUMAN; PLASMA; PRIORITY JOURNAL; PROSTATE CANCER; ANIMAL; BLOOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; METABOLISM; MOUSE MUTANT; PROSTATE TUMOR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SCINTISCANNING; TISSUE DISTRIBUTION; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; VIDEORECORDING;

ANIMALS; BIOLOGICAL TRANSPORT; BOMBESIN; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; FEMALE; HUMANS; LIGANDS; MALE; MICE; MICE, SCID; PEPTIDES; PROSTATIC NEOPLASMS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; RADIOPHARMACEUTICALS; RECEPTORS, BOMBESIN; TECHNETIUM; TISSUE DISTRIBUTION; VIDEO RECORDING;

EID: 84860743469     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.02.049     Document Type: Article

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