Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia

Journal of Controlled Release

Volumn 159, Issue 3, 2012, Pages 362-367

  McDaniel, Jonathan R ^a   MacEwan, Sarah R ^a   Dewhirst, Mark ^a,b   Chilkoti, Ashutosh ^a  

^a Duke University   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Elastin like polypeptide; Hyperthermia; Nanoparticle; Targeting; Thermosensitive

Indexed keywords

CANCER; ELASTIN-LIKE POLYPEPTIDES; HYPERTHERMIA; TARGETING; THERMO SENSITIVE;

CHEMOTHERAPY; CYTOTOXICITY; POLYPEPTIDES; TUMORS;

NANOPARTICLES;

CHIMERIC POLYPEPTIDE; CHIMERIC PROTEIN; DOXORUBICIN; ELASTIN; NANOPARTICLE; POLYPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DILUTION; DRUG CONJUGATION; DRUG CYTOTOXICITY; HYPERTHERMIA; MOUSE; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; SOLID TUMOR; TEMPERATURE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; DRUG DESIGN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HOT TEMPERATURE; MICE; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; OLIGOPEPTIDES; PEPTIDE LIBRARY; PHASE TRANSITION; SURFACE PROPERTIES; TRANSITION TEMPERATURE;

EID: 84860699882     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.02.030     Document Type: Article

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