Preclinical manufacture of anti-HER2 liposome-inserting, scFv-PEG-lipid conjugate. 2. Conjugate micelle identity, purity, stability, and potency analysis

Biotechnology Progress

Volumn 21, Issue 1, 2005, Pages 221-232

  Nellis, David F ^a   Giardina, Steven L ^a   Janini, George M ^a   Shenoy, Shilpa R ^c   Marks, James D ^d   Tsai, Richard ^d   Drummond, Daryl C ^b,e   Hong, Keelung ^b,e   Park, John W ^d   Ouellette, Thomas F ^a   Perkins, Shelley C ^a   Kirpotin, Dmitri B ^b,e  

^a SAIC FREDERICK INC   (United States)

^b CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Hermes Biosciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; AMINO ACIDS; CAPILLARITY; DIFFERENTIAL SCANNING CALORIMETRY; ENZYMES; MICELLES; POLYMERS; PROTEINS; SIZE EXCLUSION CHROMATOGRAPHY; SUSPENSIONS (FLUIDS);

BIOMOLECULAR INTERACTION ANALYSIS; PROTEIN-LIPOPOLYMER CONJUGATES; TOXICOLOGY;

LIPIDS;

EPIDERMAL GROWTH FACTOR RECEPTOR 2; IMMUNOGLOBULIN FRAGMENT; LIPOSOME; LYSOPHOSPHOLIPASE;

ARTICLE; BIOLOGICAL MODEL; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ANTAGONISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOLOGY; ION EXCHANGE CHROMATOGRAPHY; METABOLISM; METHODOLOGY; MICELLE; MOLECULAR WEIGHT; PARTICLE SIZE; POLYACRYLAMIDE GEL ELECTROPHORESIS; SEQUENCE ANALYSIS; TEMPERATURE; TIME;

CALORIMETRY, DIFFERENTIAL SCANNING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; IMMUNOGLOBULIN FRAGMENTS; LIPOSOMES; LYSOPHOSPHOLIPASE; MICELLES; MODELS, BIOLOGICAL; MOLECULAR WEIGHT; PARTICLE SIZE; RECEPTOR, ERBB-2; SEQUENCE ANALYSIS, PROTEIN; TEMPERATURE; TIME FACTORS;

INSERTION SEQUENCES;

EID: 13544251524     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp049839z     Document Type: Article

References (8)

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