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Volumn 64, Issue 8, 2012, Pages 749-755

Combination of pet imaging with viral vectors for identification of cancer metastases

Author keywords

Gene therapy; Lymph node metastases; Melanoma; Molecular imaging; Oncolytic virus; Positron emission tomography; Reporter genes

Indexed keywords

ANIMAL MODELS OF CANCER; CANCER CELLS; CANCER METASTASIS; CANCER PATIENTS; CONVENTIONAL IMAGING; HERPES SIMPLEX; LYMPH NODE METASTASIS; MELANOMA; NEOPLASTIC DISEASE; NON-INVASIVE IMAGING; NONVIRAL VECTORS; NORMAL TISSUE; OCCULT METASTASIS; PATIENT CARE; PET IMAGING; POTENTIAL BENEFITS; REPORTER GENE; REPORTER SYSTEMS; SOLID TUMORS; TARGET CELLS; THYMIDINE KINASE; VIRAL VECTORS; VIRUS-1;

EID: 84860638334     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2011.04.007     Document Type: Review
Times cited : (8)

References (82)
  • 2
    • 33750054757 scopus 로고    scopus 로고
    • Tumor and lymph node lymphangiogenesis-impact on cancer metastasis
    • Tobler N.E., Detmar M. Tumor and lymph node lymphangiogenesis-impact on cancer metastasis. J. Leukoc. Biol. 2006, 80:691-696.
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 691-696
    • Tobler, N.E.1    Detmar, M.2
  • 5
    • 67349241665 scopus 로고    scopus 로고
    • Current concepts in management of oral cancer-surgery
    • Shah J.P., Gil Z. Current concepts in management of oral cancer-surgery. Oral Oncol. 2009, 45:394-401.
    • (2009) Oral Oncol. , vol.45 , pp. 394-401
    • Shah, J.P.1    Gil, Z.2
  • 6
    • 34548251824 scopus 로고    scopus 로고
    • Integrated PET/CT system for staging and surveillance of skull base tumors
    • Gil Z., Even-Sapir E., Margalit N., Fliss D.M. Integrated PET/CT system for staging and surveillance of skull base tumors. Head Neck 2007, 29:537-545.
    • (2007) Head Neck , vol.29 , pp. 537-545
    • Gil, Z.1    Even-Sapir, E.2    Margalit, N.3    Fliss, D.M.4
  • 7
    • 38349171534 scopus 로고    scopus 로고
    • Utilizing the tumor-node-metastasis staging for prostate cancer: the sixth edition, 2002
    • Chang S.S., Amin M.B. Utilizing the tumor-node-metastasis staging for prostate cancer: the sixth edition, 2002. CA Cancer J. Clin. 2008, 58:54-59.
    • (2008) CA Cancer J. Clin. , vol.58 , pp. 54-59
    • Chang, S.S.1    Amin, M.B.2
  • 9
    • 34548416658 scopus 로고    scopus 로고
    • Whole-body magnetic resonance imaging and positron emission tomography-computed tomography in oncology
    • Schmidt G.P., Kramer H., Reiser M.F., Glaser C. Whole-body magnetic resonance imaging and positron emission tomography-computed tomography in oncology. Top. Magn. Reson. Imaging 2007, 18:193-202.
    • (2007) Top. Magn. Reson. Imaging , vol.18 , pp. 193-202
    • Schmidt, G.P.1    Kramer, H.2    Reiser, M.F.3    Glaser, C.4
  • 12
    • 0031784418 scopus 로고    scopus 로고
    • Benign causes of 18-FDG uptake on whole body imaging
    • Bakheet S.M., Powe J. Benign causes of 18-FDG uptake on whole body imaging. Semin. Nucl. Med. 1998, 28:352-358.
    • (1998) Semin. Nucl. Med. , vol.28 , pp. 352-358
    • Bakheet, S.M.1    Powe, J.2
  • 13
    • 0031718846 scopus 로고    scopus 로고
    • Rapid detection of human infections with fluorine-18 fluorodeoxyglucose and positron emission tomography: preliminary results
    • Sugawara Y., Braun D.K., Kison P.V., Russo J.E., Zasadny K.R., Wahl R.L. Rapid detection of human infections with fluorine-18 fluorodeoxyglucose and positron emission tomography: preliminary results. Eur. J. Nucl. Med. 1998, 25:1238-1243.
    • (1998) Eur. J. Nucl. Med. , vol.25 , pp. 1238-1243
    • Sugawara, Y.1    Braun, D.K.2    Kison, P.V.3    Russo, J.E.4    Zasadny, K.R.5    Wahl, R.L.6
  • 14
    • 0034020680 scopus 로고    scopus 로고
    • Exclusion of chronic osteomyelitis with F-18 fluorodeoxyglucose positron emission tomographic imaging
    • Zhuang H., Duarte P.S., Pourdehand M., Shnier D., Alavi A. Exclusion of chronic osteomyelitis with F-18 fluorodeoxyglucose positron emission tomographic imaging. Clin. Nucl. Med. 2000, 25:281-284.
    • (2000) Clin. Nucl. Med. , vol.25 , pp. 281-284
    • Zhuang, H.1    Duarte, P.S.2    Pourdehand, M.3    Shnier, D.4    Alavi, A.5
  • 15
    • 0029826105 scopus 로고    scopus 로고
    • Fluorine-18 deoxyglucose and false-positive results: a major problem in the diagnostics of oncological patients
    • Strauss L.G. Fluorine-18 deoxyglucose and false-positive results: a major problem in the diagnostics of oncological patients. Eur. J. Nucl. Med. 1996, 23:1409-1415.
    • (1996) Eur. J. Nucl. Med. , vol.23 , pp. 1409-1415
    • Strauss, L.G.1
  • 17
    • 36148985779 scopus 로고    scopus 로고
    • FDG PET/CT for the detection and evaluation of breast diseases: usefulness and limitations
    • Lim H.S., Yoon W., Chung T.W., Kim J.K., Park J.G., Kang H.K., Bom H.S., Yoon J.H. FDG PET/CT for the detection and evaluation of breast diseases: usefulness and limitations. Radiographics 2007, 27(Suppl 1):S197-S213.
    • (2007) Radiographics , vol.27 , Issue.SUPPL. 1
    • Lim, H.S.1    Yoon, W.2    Chung, T.W.3    Kim, J.K.4    Park, J.G.5    Kang, H.K.6    Bom, H.S.7    Yoon, J.H.8
  • 18
    • 79957655847 scopus 로고    scopus 로고
    • Use of molecular targeted agents for the diagnosis, staging and therapy of neuroendocrine malignancy, Cancer Imaging, 10 Spec no A S83-91.
    • R.J. Hicks, Use of molecular targeted agents for the diagnosis, staging and therapy of neuroendocrine malignancy, Cancer Imaging, 10 Spec no A S83-91.
    • Hicks, R.J.1
  • 20
    • 44149101969 scopus 로고    scopus 로고
    • A new acycloguanosine-specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs
    • Likar Y., Dobrenkov K., Olszewska M., Vider E., Shenker L., Cai S., Pillarsetty N., Hricak H., Ponomarev V. A new acycloguanosine-specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs. J. Nucl. Med. 2008, 49:713-720.
    • (2008) J. Nucl. Med. , vol.49 , pp. 713-720
    • Likar, Y.1    Dobrenkov, K.2    Olszewska, M.3    Vider, E.4    Shenker, L.5    Cai, S.6    Pillarsetty, N.7    Hricak, H.8    Ponomarev, V.9
  • 21
    • 35948996991 scopus 로고    scopus 로고
    • Nerve-sparing therapy with oncolytic herpes virus for cancers with neural invasion
    • Gil Z., Rein A., Brader P., Li S., Shah J.P., Fong Y., Wong R.J. Nerve-sparing therapy with oncolytic herpes virus for cancers with neural invasion. Clin. Cancer Res. 2007, 13:6479-6485.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6479-6485
    • Gil, Z.1    Rein, A.2    Brader, P.3    Li, S.4    Shah, J.P.5    Fong, Y.6    Wong, R.J.7
  • 22
    • 44949157886 scopus 로고    scopus 로고
    • Attenuated multimutated herpes simplex virus∓1 effectively treats prostate carcinomas with neural invasion while preserving nerve function
    • Kelly K., Brader P., Rein A., Shah J.P., Wong R.J., Fong Y., Gil Z. Attenuated multimutated herpes simplex virus∓1 effectively treats prostate carcinomas with neural invasion while preserving nerve function. FASEB J. 2008, 22:1839-1848.
    • (2008) FASEB J. , vol.22 , pp. 1839-1848
    • Kelly, K.1    Brader, P.2    Rein, A.3    Shah, J.P.4    Wong, R.J.5    Fong, Y.6    Gil, Z.7
  • 23
    • 0038529610 scopus 로고    scopus 로고
    • Noninvasive imaging of lentiviral-mediated reporter gene expression in living mice
    • De A., Lewis X.Z., Gambhir S.S. Noninvasive imaging of lentiviral-mediated reporter gene expression in living mice. Mol. Ther. 2003, 7:681-691.
    • (2003) Mol. Ther. , vol.7 , pp. 681-691
    • De, A.1    Lewis, X.Z.2    Gambhir, S.S.3
  • 26
    • 34250743850 scopus 로고    scopus 로고
    • Human reporter genes: potential use in clinical studies
    • Serganova I., Ponomarev V., Blasberg R. Human reporter genes: potential use in clinical studies. Nucl. Med. Biol. 2007, 34:791-807.
    • (2007) Nucl. Med. Biol. , vol.34 , pp. 791-807
    • Serganova, I.1    Ponomarev, V.2    Blasberg, R.3
  • 27
    • 41649110649 scopus 로고    scopus 로고
    • Imaging in the era of molecular oncology
    • Weissleder R., Pittet M.J. Imaging in the era of molecular oncology. Nature 2008, 452:580-589.
    • (2008) Nature , vol.452 , pp. 580-589
    • Weissleder, R.1    Pittet, M.J.2
  • 30
    • 27644562215 scopus 로고
    • Effect of inoculation of the viruses of influenza A and herpes simplex on the growth of transplantable tumors in mice
    • Moore A.E. Effect of inoculation of the viruses of influenza A and herpes simplex on the growth of transplantable tumors in mice. Cancer 1949, 2:516-524.
    • (1949) Cancer , vol.2 , pp. 516-524
    • Moore, A.E.1
  • 32
    • 41649118744 scopus 로고    scopus 로고
    • Utility of a herpes oncolytic virus for the detection of neural invasion by cancer
    • Gil Z., Kelly K.J., Brader P., Shah J.P., Fong Y., Wong R.J. Utility of a herpes oncolytic virus for the detection of neural invasion by cancer. Neoplasia 2008, 10:347-353.
    • (2008) Neoplasia , vol.10 , pp. 347-353
    • Gil, Z.1    Kelly, K.J.2    Brader, P.3    Shah, J.P.4    Fong, Y.5    Wong, R.J.6
  • 33
    • 42649120648 scopus 로고    scopus 로고
    • Oncolytic virotherapy for malignant melanoma with herpes simplex virus type 1 mutant HF10
    • Watanabe D., Goshima F., Mori I., Tamada Y., Matsumoto Y., Nishiyama Y. Oncolytic virotherapy for malignant melanoma with herpes simplex virus type 1 mutant HF10. J. Dermatol. Sci. 2008, 50:185-196.
    • (2008) J. Dermatol. Sci. , vol.50 , pp. 185-196
    • Watanabe, D.1    Goshima, F.2    Mori, I.3    Tamada, Y.4    Matsumoto, Y.5    Nishiyama, Y.6
  • 36
    • 0041326572 scopus 로고    scopus 로고
    • The replication-competent oncolytic herpes simplex mutant virus NV1066 is effective in the treatment of esophageal cancer
    • Stiles B.M., Bhargava A., Adusumilli P.S., Stanziale S.F., Kim T.H., Rusch V.W., Fong Y. The replication-competent oncolytic herpes simplex mutant virus NV1066 is effective in the treatment of esophageal cancer. Surgery 2003, 134:357-364.
    • (2003) Surgery , vol.134 , pp. 357-364
    • Stiles, B.M.1    Bhargava, A.2    Adusumilli, P.S.3    Stanziale, S.F.4    Kim, T.H.5    Rusch, V.W.6    Fong, Y.7
  • 38
    • 0028154016 scopus 로고
    • Competitive quantitative PCR analysis of herpes simplex virus type 1 DNA and latency-associated transcript RNA in latently infected cells of the rat brain
    • Ramakrishnan R., Fink D.J., Jiang G., Desai P., Glorioso J.C., Levine M. Competitive quantitative PCR analysis of herpes simplex virus type 1 DNA and latency-associated transcript RNA in latently infected cells of the rat brain. J. Virol. 1994, 68:1864-1873.
    • (1994) J. Virol. , vol.68 , pp. 1864-1873
    • Ramakrishnan, R.1    Fink, D.J.2    Jiang, G.3    Desai, P.4    Glorioso, J.C.5    Levine, M.6
  • 39
    • 0025280142 scopus 로고
    • In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus)
    • Meignier B., Martin B., Whitley R.J., Roizman B. In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus). J. Infect. Dis. 1990, 162:313-321.
    • (1990) J. Infect. Dis. , vol.162 , pp. 313-321
    • Meignier, B.1    Martin, B.2    Whitley, R.J.3    Roizman, B.4
  • 41
    • 33845754406 scopus 로고    scopus 로고
    • Differential biodistribution of adenoviral vector in vivo as monitored by bioluminescence imaging and quantitative polymerase chain reaction
    • Johnson M., Huyn S., Burton J., Sato M., Wu L. Differential biodistribution of adenoviral vector in vivo as monitored by bioluminescence imaging and quantitative polymerase chain reaction. Hum. Gene Ther. 2006, 17:1262-1269.
    • (2006) Hum. Gene Ther. , vol.17 , pp. 1262-1269
    • Johnson, M.1    Huyn, S.2    Burton, J.3    Sato, M.4    Wu, L.5
  • 44
    • 41549111171 scopus 로고    scopus 로고
    • Sensitivity of squamous cell carcinoma lymph node metastases to herpes oncolytic therapy
    • Yu Z., Li S., Huang Y.Y., Lin S.F., Fong Y., Wong R.J. Sensitivity of squamous cell carcinoma lymph node metastases to herpes oncolytic therapy. Clin. Cancer Res. 2008, 14:1897-1904.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 1897-1904
    • Yu, Z.1    Li, S.2    Huang, Y.Y.3    Lin, S.F.4    Fong, Y.5    Wong, R.J.6
  • 45
    • 35148841515 scopus 로고    scopus 로고
    • Systemic therapy of spontaneous prostate cancer in transgenic mice with oncolytic herpes simplex viruses
    • Varghese S., Rabkin S.D., Nielsen G.P., MacGarvey U., Liu R., Martuza R.L. Systemic therapy of spontaneous prostate cancer in transgenic mice with oncolytic herpes simplex viruses. Cancer Res. 2007, 67:9371-9379.
    • (2007) Cancer Res. , vol.67 , pp. 9371-9379
    • Varghese, S.1    Rabkin, S.D.2    Nielsen, G.P.3    MacGarvey, U.4    Liu, R.5    Martuza, R.L.6
  • 46
    • 33646240591 scopus 로고    scopus 로고
    • Real-time diagnostic imaging of tumors and metastases by use of a replication-competent herpes vector to facilitate minimally invasive oncological surgery
    • Adusumilli P.S., Stiles B.M., Chan M.K., Eisenberg D.P., Yu Z., Stanziale S.F., Huq R., Wong R.J., Rusch V.W., Fong Y. Real-time diagnostic imaging of tumors and metastases by use of a replication-competent herpes vector to facilitate minimally invasive oncological surgery. FASEB J. 2006, 20:726-728.
    • (2006) FASEB J. , vol.20 , pp. 726-728
    • Adusumilli, P.S.1    Stiles, B.M.2    Chan, M.K.3    Eisenberg, D.P.4    Yu, Z.5    Stanziale, S.F.6    Huq, R.7    Wong, R.J.8    Rusch, V.W.9    Fong, Y.10
  • 47
    • 0036019202 scopus 로고    scopus 로고
    • Oncolytic herpesvirus effectively treats murine squamous cell carcinoma and spreads by natural lymphatics to treat sites of lymphatic metastases
    • Wong R.J., Joe J.K., Kim S.H., Shah J.P., Horsburgh B., Fong Y. Oncolytic herpesvirus effectively treats murine squamous cell carcinoma and spreads by natural lymphatics to treat sites of lymphatic metastases. Hum. Gene Ther. 2002, 13:1213-1223.
    • (2002) Hum. Gene Ther. , vol.13 , pp. 1213-1223
    • Wong, R.J.1    Joe, J.K.2    Kim, S.H.3    Shah, J.P.4    Horsburgh, B.5    Fong, Y.6
  • 48
    • 0024447589 scopus 로고
    • Langerhans cell density and activity in mouse skin and lymph nodes affect herpes simplex type 1 (HSV-1) pathogenicity
    • Sprecher E., Becker Y. Langerhans cell density and activity in mouse skin and lymph nodes affect herpes simplex type 1 (HSV-1) pathogenicity. Arch. Virol. 1989, 107:191-205.
    • (1989) Arch. Virol. , vol.107 , pp. 191-205
    • Sprecher, E.1    Becker, Y.2
  • 49
    • 33745291501 scopus 로고    scopus 로고
    • Real-time intraoperative detection of breast cancer axillary lymph node metastases using a green fluorescent protein-expressing herpes virus
    • (discussion 830-822)
    • Eisenberg D.P., Adusumilli P.S., Hendershott K.J., Chung S., Yu Z., Chan M.K., Hezel M., Wong R.J., Fong Y. Real-time intraoperative detection of breast cancer axillary lymph node metastases using a green fluorescent protein-expressing herpes virus. Ann. Surg. 2006, 243:824-830. (discussion 830-822).
    • (2006) Ann. Surg. , vol.243 , pp. 824-830
    • Eisenberg, D.P.1    Adusumilli, P.S.2    Hendershott, K.J.3    Chung, S.4    Yu, Z.5    Chan, M.K.6    Hezel, M.7    Wong, R.J.8    Fong, Y.9
  • 52
    • 9544242826 scopus 로고    scopus 로고
    • Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy
    • Tjuvajev J.G., Finn R., Watanabe K., Joshi R., Oku T., Kennedy J., Beattie B., Koutcher J., Larson S., Blasberg R.G. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res. 1996, 56:4087-4095.
    • (1996) Cancer Res. , vol.56 , pp. 4087-4095
    • Tjuvajev, J.G.1    Finn, R.2    Watanabe, K.3    Joshi, R.4    Oku, T.5    Kennedy, J.6    Beattie, B.7    Koutcher, J.8    Larson, S.9    Blasberg, R.G.10
  • 55
    • 18244428952 scopus 로고    scopus 로고
    • Synthesis and preliminary evaluation of 9-(4-[18F]-fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET
    • Alauddin M.M., Conti P.S. Synthesis and preliminary evaluation of 9-(4-[18F]-fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET. Nucl. Med. Biol. 1998, 25:175-180.
    • (1998) Nucl. Med. Biol. , vol.25 , pp. 175-180
    • Alauddin, M.M.1    Conti, P.S.2
  • 56
    • 33745080072 scopus 로고    scopus 로고
    • Preclinical safety evaluation of 18F-FHBG: a PET reporter probe for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk's expression
    • Yaghoubi S.S., Couto M.A., Chen C.C., Polavaram L., Cui G., Sen L., Gambhir S.S. Preclinical safety evaluation of 18F-FHBG: a PET reporter probe for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk's expression. J. Nucl. Med. 2006, 47:706-715.
    • (2006) J. Nucl. Med. , vol.47 , pp. 706-715
    • Yaghoubi, S.S.1    Couto, M.A.2    Chen, C.C.3    Polavaram, L.4    Cui, G.5    Sen, L.6    Gambhir, S.S.7
  • 58
    • 0030204116 scopus 로고    scopus 로고
    • 9-[(3-[18F]-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG): a potential imaging agent of viral infection and gene therapy using PET
    • Alauddin M.M., Conti P.S., Mazza S.M., Hamzeh F.M., Lever J.R. 9-[(3-[18F]-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG): a potential imaging agent of viral infection and gene therapy using PET. Nucl. Med. Biol. 1996, 23:787-792.
    • (1996) Nucl. Med. Biol. , vol.23 , pp. 787-792
    • Alauddin, M.M.1    Conti, P.S.2    Mazza, S.M.3    Hamzeh, F.M.4    Lever, J.R.5
  • 59
    • 33645214648 scopus 로고    scopus 로고
    • 18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers
    • Buursma A.R., Rutgers V., Hospers G.A., Mulder N.H., Vaalburg W., de Vries E.F. 18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers. Nucl. Med. Commun. 2006, 27:25-30.
    • (2006) Nucl. Med. Commun. , vol.27 , pp. 25-30
    • Buursma, A.R.1    Rutgers, V.2    Hospers, G.A.3    Mulder, N.H.4    Vaalburg, W.5    de Vries, E.F.6
  • 61
    • 34249021435 scopus 로고    scopus 로고
    • In vivo evaluation of 2'-deoxy-2'-[(18)F]fluoro-5-iodo-1-beta-D-arabinofuranosyluracil ([18F]FIAU) and 2'-deoxy-2'-[18F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression
    • Alauddin M.M., Shahinian A., Park R., Tohme M., Fissekis J.D., Conti P.S. In vivo evaluation of 2'-deoxy-2'-[(18)F]fluoro-5-iodo-1-beta-D-arabinofuranosyluracil ([18F]FIAU) and 2'-deoxy-2'-[18F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression. Eur. J. Nucl. Med. Mol. Imaging 2007, 34:822-829.
    • (2007) Eur. J. Nucl. Med. Mol. Imaging , vol.34 , pp. 822-829
    • Alauddin, M.M.1    Shahinian, A.2    Park, R.3    Tohme, M.4    Fissekis, J.D.5    Conti, P.S.6
  • 63
    • 58749113471 scopus 로고    scopus 로고
    • 5-[18F]Fluoroalkyl pyrimidine nucleosides: probes for positron emission tomography imaging of herpes simplex virus type 1 thymidine kinase gene expression
    • Chacko A.M., Blankemeyer E., Lieberman B.P., Qu W., Kung H.F. 5-[18F]Fluoroalkyl pyrimidine nucleosides: probes for positron emission tomography imaging of herpes simplex virus type 1 thymidine kinase gene expression. Nucl. Med. Biol. 2009, 36:29-38.
    • (2009) Nucl. Med. Biol. , vol.36 , pp. 29-38
    • Chacko, A.M.1    Blankemeyer, E.2    Lieberman, B.P.3    Qu, W.4    Kung, H.F.5
  • 68
  • 69
    • 58149464705 scopus 로고    scopus 로고
    • Real-time intraoperative detection of melanoma lymph node metastases using recombinant vaccinia virus GLV-1h68 in an immunocompetent animal model
    • Kelly K.J., Brader P., Woo Y., Li S., Chen N., Yu Y.A., Szalay A.A., Fong Y. Real-time intraoperative detection of melanoma lymph node metastases using recombinant vaccinia virus GLV-1h68 in an immunocompetent animal model. Int. J. Cancer 2009, 124:911-918.
    • (2009) Int. J. Cancer , vol.124 , pp. 911-918
    • Kelly, K.J.1    Brader, P.2    Woo, Y.3    Li, S.4    Chen, N.5    Yu, Y.A.6    Szalay, A.A.7    Fong, Y.8
  • 72
    • 1242338786 scopus 로고    scopus 로고
    • Imaging tri-fusion multimodality reporter gene expression in living subjects
    • Ray P., De A., Min J.J., Tsien R.Y., Gambhir S.S. Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res. 2004, 64:1323-1330.
    • (2004) Cancer Res. , vol.64 , pp. 1323-1330
    • Ray, P.1    De, A.2    Min, J.J.3    Tsien, R.Y.4    Gambhir, S.S.5
  • 73
    • 78651240824 scopus 로고    scopus 로고
    • Tumor-specific imaging through progression elevated gene-3 promoter-driven gene expression
    • Bhang H.E., Gabrielson K.L., Laterra J., Fisher P.B., Pomper M.G. Tumor-specific imaging through progression elevated gene-3 promoter-driven gene expression. Nat. Med. 2011, 17:123-129.
    • (2011) Nat. Med. , vol.17 , pp. 123-129
    • Bhang, H.E.1    Gabrielson, K.L.2    Laterra, J.3    Fisher, P.B.4    Pomper, M.G.5
  • 75
    • 0034644133 scopus 로고    scopus 로고
    • Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulate basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells
    • Su Z., Shi Y., Fisher P.B. Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulate basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells. Oncogene 2000, 19:3411-3421.
    • (2000) Oncogene , vol.19 , pp. 3411-3421
    • Su, Z.1    Shi, Y.2    Fisher, P.B.3
  • 78
    • 0037314610 scopus 로고    scopus 로고
    • A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
    • Hecht J.R., Bedford R., Abbruzzese J.L., Lahoti S., Reid T.R., Soetikno R.M., Kirn D.H., Freeman S.M. A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin. Cancer Res. 2003, 9:555-561.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 555-561
    • Hecht, J.R.1    Bedford, R.2    Abbruzzese, J.L.3    Lahoti, S.4    Reid, T.R.5    Soetikno, R.M.6    Kirn, D.H.7    Freeman, S.M.8
  • 81
    • 76749157276 scopus 로고    scopus 로고
    • Different strategies for reducing intestinal background radioactivity associated with imaging HSV1-tk expression using established radionucleoside probes, Mol. Imaging
    • A. Ruggiero, P. Brader, I. Serganova, P. Zanzonico, S. Cai, N.S. Lipman, H. Hricak, R.G. Blasberg, Different strategies for reducing intestinal background radioactivity associated with imaging HSV1-tk expression using established radionucleoside probes, Mol. Imaging 9 (2010) 47-58.
    • (2010) , vol.9 , pp. 47-58
    • Ruggiero, A.1    Brader, P.2    Serganova, I.3    Zanzonico, P.4    Cai, S.5    Lipman, N.S.6    Hricak, H.7    Blasberg, R.G.8


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