메뉴 건너뛰기




Volumn 34, Issue 6, 2007, Pages 822-829

In vivo evaluation of 2′-deoxy-2′-[18F]fluoro-5- iodo-1-β-D-arabinofuranosyluracil ([18F]FIAU) and 2′-deoxy-2′-[18F]fluoro-5-ethyl-1-β-D- arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression

Author keywords

FEAU; FIAU; Gene expression; HSV tk; PET

Indexed keywords

2' DEOXY 2' FLUORO 5 ETHYL 1 BETA DEXTRO ARABINOFURANOSYLURACIL F 18; 2' DEOXY 2' FLUORO 5 IODO 1 BETA DEXTRO ARABINOFURANOSYLURACIL F 18; FLUORINE 18; TRACER; TRITIUM; UNCLASSIFIED DRUG;

EID: 34249021435     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-006-0305-1     Document Type: Article
Times cited : (52)

References (35)
  • 2
    • 0027548077 scopus 로고
    • Clinical protocols: Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir
    • Oldfield EH, Ram Zvi, Culver KW, Blease RM, DeVroom HL, Anderson WF. Clinical protocols: gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir. Hum Gene Ther 1993;4:39-69.
    • (1993) Hum Gene Ther , vol.4 , pp. 39-69
    • Oldfield, E.H.1    Culver, K.W.2    Blease, R.M.3    Devroom, H.L.4    Anderson, W.F.5
  • 3
    • 0031463632 scopus 로고    scopus 로고
    • Therapy of malignant brain tumors by intratumoral implantation of retroviral vector producing cells
    • Ram Z, Culver KW, Oshiro EM, Viola JJ, DeVroom HL, Otto E, et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector producing cells. Nat Med 1997;3:1354-61.
    • (1997) Nat Med , vol.3 , pp. 1354-1361
    • Ram, Z.1    Culver, K.W.2    Oshiro, E.M.3    Viola, J.J.4    Devroom, H.L.5    Otto, E.6
  • 4
    • 0035138943 scopus 로고    scopus 로고
    • Reporter genes and imagene
    • Urbain JC. Reporter genes and imagene. J Nucl Med 2001;42:106-9.
    • (2001) J Nucl Med , vol.42 , pp. 106-109
    • Urbain, J.C.1
  • 5
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW, Ram Zvi, Wallbridge S, Ishi H, Oldfield EH, Blaese RM. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992;256:1550-2.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Zvi, R.2    Wallbridge, S.3    Ishi, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 6
    • 0025444099 scopus 로고
    • Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene
    • Moolten FL, Wells JM, Heyman RA, Evans RM. Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene. Hum Gene Ther 1990;1:125-34.
    • (1990) Hum Gene Ther , vol.1 , pp. 125-134
    • Moolten, F.L.1    Wells, J.M.2    Heyman, R.A.3    Evans, R.M.4
  • 7
    • 0033029295 scopus 로고    scopus 로고
    • 18F]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors
    • 18F]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors. Nucl Med Biol 1999;26:371-6.
    • (1999) Nucl Med Biol , vol.26 , pp. 371-376
    • Alauddin, M.M.1    Kundu, R.2    Gordon, E.M.3    Conti, P.S.4
  • 8
  • 9
    • 0344564162 scopus 로고    scopus 로고
    • Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo
    • Tjuvajev JG, Chen SH, Joshi A, Joshi R, Guo ZS, Balatoni J, et al. Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo. Cancer Res 1999;59:5186-93.
    • (1999) Cancer Res , vol.59 , pp. 5186-5193
    • Tjuvajev, J.G.1    Chen, S.H.2    Joshi, A.3    Joshi, R.4    Guo, Z.S.5    Balatoni, J.6
  • 10
    • 0031039313 scopus 로고    scopus 로고
    • Monitoring gene therapy with herpes simplex virus thymidine kinase in hepatoma cells: Uptake of specific substrates
    • Haberkorn U, Altmann A, Morr I, Knopf K, Germann C, Haeckel R, et al. Monitoring gene therapy with herpes simplex virus thymidine kinase in hepatoma cells: uptake of specific substrates. J Nucl Med 1997;38:287-94.
    • (1997) J Nucl Med , vol.38 , pp. 287-294
    • Haberkorn, U.1    Altmann, A.2    Morr, I.3    Knopf, K.4    Germann, C.5    Haeckel, R.6
  • 11
    • 0035300468 scopus 로고    scopus 로고
    • Positron emission tomography-based imaging of transgene expression mediated by replication conditional, oncolytic herpes simplex virus type-1 mutant vectors of cancer
    • Jacobs A, Tjuvajev JG, Dubrovin M, Akhurst T, Balatoni J, Beattie B, et al. Positron emission tomography-based imaging of transgene expression mediated by replication conditional, oncolytic herpes simplex virus type-1 mutant vectors of cancer. Cancer Res 2001;61:2983-95.
    • (2001) Cancer Res , vol.61 , pp. 2983-2995
    • Jacobs, A.1    Tjuvajev, J.G.2    Dubrovin, M.3    Akhurst, T.4    Balatoni, J.5    Beattie, B.6
  • 13
    • 17144471900 scopus 로고    scopus 로고
    • Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography
    • Tjuvajev JG, Avril N, Oku T, Sasajima T, Miyagawa T, Joshi R, et al. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res 1998;58:4333-41.
    • (1998) Cancer Res , vol.58 , pp. 4333-4341
    • Tjuvajev, J.G.1    Avril, N.2    Oku, T.3    Sasajima, T.4    Miyagawa, T.5    Joshi, R.6
  • 14
    • 0033827201 scopus 로고    scopus 로고
    • Quantification of gene expression by imaging reporter gene expression in living animals
    • Yu Y, Annala AJ, Barrio JR, Toyokuni T, Satyamurthy N, Namavari M, et al. Quantification of gene expression by imaging reporter gene expression in living animals. Nat Med 2000;6:933-7.
    • (2000) Nat Med , vol.6 , pp. 933-937
    • Yu, Y.1    Annala, A.J.2    Barrio, J.R.3    Toyokuni, T.4    Satyamurthy, N.5    Namavari, M.6
  • 17
    • 0026499283 scopus 로고
    • L-Thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth
    • Spadari S, Maga G, Focher F, Ciarrocchi G, Manservigi R, Arcamone F, et al. L-Thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth. J Med Chem 1992;35:4214-20.
    • (1992) J Med Chem , vol.35 , pp. 4214-4220
    • Spadari, S.1    Maga, G.2    Focher, F.3    Ciarrocchi, G.4    Manservigi, R.5    Arcamone, F.6
  • 18
    • 0018331237 scopus 로고
    • Nucleosides 110. Synthesis and herpes virus activity of some 2′-fluoro-2′-deoxyarabinofuranosyl pyrimidine nucleosides
    • Watanabe KA, Richmond W, Hirota K, Lopez C, Fox JJ. Nucleosides 110. Synthesis and herpes virus activity of some 2′-fluoro-2′- deoxyarabinofuranosyl pyrimidine nucleosides. J Med Chem 1979;22:21-4.
    • (1979) J Med Chem , vol.22 , pp. 21-24
    • Watanabe, K.A.1    Richmond, W.2    Hirota, K.3    Lopez, C.4    Fox, J.J.5
  • 20
    • 18244428952 scopus 로고    scopus 로고
    • 18F]-FHBG): A new potential imaging agent for viral infection and gene therapy using PET
    • 18F]-FHBG): a new potential imaging agent for viral infection and gene therapy using PET. Nucl Med Biol 1998;25:175-80.
    • (1998) Nucl Med Biol , vol.25 , pp. 175-180
    • Alauddin, M.M.1    Conti, P.S.2
  • 24
    • 0042473079 scopus 로고    scopus 로고
    • Evaluation of 2′-deoxy-2′-fluoro-5-methyl-1-β-D- arabinofuranosyluracil (FMAU) as a potential gene imaging agent for HSV-tk expression in vivo
    • Alauddin MM, Shahinian A, Gordon EM, Conti PS. Evaluation of 2′-deoxy-2′-fluoro-5-methyl-1-β-D-arabinofuranosyluracil (FMAU) as a potential gene imaging agent for HSV-tk expression in vivo. Mol Imaging 2002;1:74-81.
    • (2002) Mol Imaging , vol.1 , pp. 74-81
    • Alauddin, M.M.1    Shahinian, A.2    Gordon, E.M.3    Conti, P.S.4
  • 26
    • 0242355152 scopus 로고    scopus 로고
    • 14C]FIAU for imaging HSV1-tk reporter gene expression: Adenoviral infection vs. stable transfection
    • 14C]FIAU for imaging HSV1-tk reporter gene expression: adenoviral infection vs. stable transfection. Eur J Nucl Med Mol Imaging 2003;30:1547-60.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 1547-1560
    • Min, J.J.1    Iyer, M.2    Gambhir, S.S.3
  • 30
    • 0021288411 scopus 로고
    • Nucleosides 129. Synthesis of antiviral nucleosides: 5-Alkenyl 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)uracils
    • Watanabe KA, Su T-L, Reichman U, Greenberg N, Lopez C, Fox JJ. Nucleosides 129. Synthesis of antiviral nucleosides: 5-Alkenyl 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)uracils. J Med Chem 1994;27:91-4.
    • (1994) J Med Chem , vol.27 , pp. 91-94
    • Watanabe, K.A.1    Su, T.-L.2    Reichman, U.3    Greenberg, N.4    Lopez, C.5    Fox, J.J.6
  • 32
    • 0029442275 scopus 로고
    • An improved retroviral vector encoding the herpes simplex virus thymidine kinase gene increasing antitumor efficacy in vivo
    • Lyons RM, Forry-Schaudies S, Otto E, Wey C, Patilkoota V, Kaloss M, et al. An improved retroviral vector encoding the herpes simplex virus thymidine kinase gene increasing antitumor efficacy in vivo. Cancer Gene Ther 1995;2:273-80.
    • (1995) Cancer Gene Ther , vol.2 , pp. 273-280
    • Lyons, R.M.1    Forry-Schaudies, S.2    Otto, E.3    Wey, C.4    Patilkoota, V.5    Kaloss, M.6
  • 33
    • 0031949646 scopus 로고    scopus 로고
    • Mechanism for ganciclovir resistance in gastrointestinal tumor cells transduced with retroviral vector containing the herpes simplex virus thymidine kinase gene
    • Yang L, Hwang R, Chiang Y, Gordon EM, Anderson WF, Parekh D. Mechanism for ganciclovir resistance in gastrointestinal tumor cells transduced with retroviral vector containing the herpes simplex virus thymidine kinase gene. Clin Cancer Res 1998;4:731-41.
    • (1998) Clin Cancer Res , vol.4 , pp. 731-741
    • Yang, L.1    Hwang, R.2    Chiang, Y.3    Gordon, E.M.4    Anderson, W.F.5    Parekh, D.6
  • 34
    • 0028567822 scopus 로고
    • Toxicity, metabolism, DNA incorporation with lack of repair, and lactate production for 1-(2′-fluoro-2′-deoxy-β-D-arabinofuranosyl)-5- iodouracil in U937 and MOLT-4 cells
    • Klecker RW, Kakti AG, Collins JM. Toxicity, metabolism, DNA incorporation with lack of repair, and lactate production for 1-(2′-fluoro-2′- deoxy-β-D-arabinofuranosyl)-5-iodouracil in U937 and MOLT-4 cells. Mol Pharmacol 1994;46:1204-9.
    • (1994) Mol Pharmacol , vol.46 , pp. 1204-1209
    • Klecker, R.W.1    Kakti, A.G.2    Collins, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.