Hypoxia-inducible factor 1 mediates nasal polypogenesis by inducing epithelial-to-mesenchymal transition

American Journal of Respiratory and Critical Care Medicine

Volumn 185, Issue 9, 2012, Pages 944-954

  Shin, Hyun Woo ^a   Cho, Kumsun ^a   Kim, Dae Woo ^b   Han, Doo Hee ^a   Khalmuratova, Roza ^b   Kim, Sang Wook ^b   Jeon, Sea Yuong ^b   Min, Yang Gi ^a   Lee, Chul Hee ^a   Rhee, Chae Seo ^a   Park, Jong Wan ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Gyeongsang National University School of Medicine   (South Korea)

Author keywords

Epithelial to mesenchymal transition; Hypoxia; Hypoxia inducible factor 1; Nasal polyposis; Smad3

Indexed keywords

2 METHOXYESTRADIOL; ALPHA SMOOTH MUSCLE ACTIN; BETA CATENIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TANESPIMYCIN; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SHAPE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; NOSE POLYP; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ACTINS; ANIMALS; ANOXIA; CADHERINS; CASE-CONTROL STUDIES; CELL LINE; DISEASE MODELS, ANIMAL; EPITHELIAL-MESENCHYMAL TRANSITION; FLOW CYTOMETRY; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; IMMUNOBLOTTING; MICE; MICE, INBRED BALB C; NASAL POLYPS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84860629097     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201109-1706OC     Document Type: Article

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