TGF-β signaling and collagen deposition in chronic rhinosinusitis

Journal of Allergy and Clinical Immunology

Volumn 124, Issue 2, 2009, Pages

  Van Bruaene, Nicholas ^a   Derycke, Lara ^a   Perez Novo, Claudina Angela ^a   Gevaert, Philippe ^a   Holtappels, Gabriele ^a   De Ruyck, Natalie ^a   Cuvelier, Claude ^b   Van Cauwenberge, Paul ^a   Bachert, Claus ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Chronic rhinosinusitis; collagen; inflammation; nasal polyposis; phospho Smad 2; remodeling; TGF

Indexed keywords

COLLAGEN; COLLAGEN FIBER; MESSENGER RNA; SIGNAL PEPTIDE; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROL GROUP; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NOSE POLYP; NOSE SEPTUM RECONSTRUCTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHINOSINUSITIS; STAINING;

EID: 64649098615     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.04.013     Document Type: Article

References (26)

1. van Zele T., Claeys S., Gevaert P., Van Maele G., Holtappels G., Van Cauwenberge P., et al. Differentiation of chronic sinus diseases by measurement of inflammatory mediators. Allergy 61 (2006) 1280-1289
2. Van Bruaene N., Perez-Novo C.A., Basinski T.M., van Zele T., Holtappels G., De Ruyck N., et al. T-cell regulation in chronic paranasal sinus disease. J Allergy Clin Immunol 121 (2008) 1435-1441 e1-3
3. Bachert C., Gevaert P., Holtappels G., Johansson S.G., and Van Cauwenberge P. Total and specific IgE in nasal polyps is related to local eosinophilic inflammation. J Allergy Clin Immunol 107 (2001) 607-614
4. Bachert C., Gevaert P., Holtappels G., Cuvelier C., and Van Cauwenberge P. Nasal polyposis: from cytokines to growth. Am J Rhinol 14 (2000) 279-290
5. Huber S., Schramm C., Lehr H.A., Mann A., Schmitt S., Becker C., et al. Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells. J Immunol 173 (2004) 6526-6531
6. Redington A.E. Airway fibrosis in asthma: mechanisms, consequences, and potential for therapeutic intervention. Monaldi Arch Chest Dis 55 (2000) 317-323
7. Balzar S., Chu H.W., Silkoff P., Cundall M., Trudeau J.B., Strand M., et al. Increased TGF-beta2 in severe asthma with eosinophilia. J Allergy Clin Immunol 115 (2005) 110-117
8. Heldin C.H., Miyazono K., and ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390 (1997) 465-471
9. Whittaker P., Kloner R.A., Boughner D.R., and Pickering J.G. Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light. Basic Res Cardiol 89 (1994) 397-410
10. Fokkens W., Lund V., and Mullol J. European position paper on rhinosinusitis and nasal polyps 2007. Rhinol Suppl 20 (2007) 1-136
11. Meltzer E.O., Hamilos D.L., Hadley J.A., Lanza D.C., Marple B.F., Nicklas R.A., et al. Rhinosinusitis: establishing definitions for clinical research and patient care. J Allergy Clin Immunol 114 6 suppl (2004) 155-212
12. Perez-Novo C.A., Claeys C., Speleman F., Van Cauwenberge P., Bachert C., and Vandesompele J. Impact of RNA quality on reference gene expression stability. Biotechniques 39 52 (2005) 54, 56
13. Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3 7 (2002) RESEARCH0034
14. Junqueira L.C., Bignolas G., and Brentani R.R. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 11 (1979) 447-455
15. Figueiredo C.R., Santos R.P., Silva I.D., and Weckx L.L. Microarray cDNA to identify inflammatory genes in nasal polyposis. Am J Rhinol 21 (2007) 231-235
16. Blobe G.C., Schiemann W.P., and Lodish H.F. Role of transforming growth factor beta in human disease. N Engl J Med 342 (2000) 1350-1358
17. Massague J. TGF-beta signal transduction. Annu Rev Biochem 67 (1998) 753-791
18. Massague J., and Wotton D. Transcriptional control by the TGF-beta/Smad signaling system. EMBO J 19 (2000) 1745-1754
19. Rostkowska-Nadolska B., Kapral M., Mazurek U., Gawron W., and Pres K. Co-expression of the TGF-beta1 and TGF- beta2 isoforms in nasal polyps and in healthy mucosa. Postepy Hig Med Dosw (Online) 61 (2007) 702-707
20. Watelet J.B., Bachert C., Claeys C., and Van Cauwenberge P. Matrix metalloproteinases MMP-7, MMP-9 and their tissue inhibitor TIMP-1: expression in chronic sinusitis vs nasal polyposis. Allergy 59 (2004) 54-60
21. Kostamo K., Tervahartiala T., Sorsa T., Richardson M., and Toskala E. Metalloproteinase function in chronic rhinosinusitis with nasal polyposis. Laryngoscope 117 (2007) 638-643
22. Lechapt-Zalcman E., Coste A., d'Ortho M.P., Frisdal E., Harf A., Lafuma C., et al. Increased expression of matrix metalloproteinase-9 in nasal polyps. J Pathol 193 (2001) 233-241
23. Chen Y.S., Langhammer T., Westhofen M., and Lorenzen J. Relationship between matrix metalloproteinases MMP-2, MMP-9, tissue2 inhibitor of matrix metalloproteinases-1 and IL-5, IL-8 in nasal polyps. Allergy 62 (2007) 66-72
24. Hamilos D.L., Thawley S.E., Kramper M.A., Kamil A., and Hamid Q.A. Effect of intranasal fluticasone on cellular infiltration, endothelial adhesion molecule expression, and proinflammatory cytokine mRNA in nasal polyp disease. J Allergy Clin Immunol 103 1 pt 1 (1999) 79-87
25. Chakir J., Shannon J., Molet S., Fukakusa M., Elias J., Laviolette M., et al. Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression. J Allergy Clin Immunol 111 (2003) 1293-1298
26. Bergeron C., Hauber H.P., Gotfried M., Newman K., Dhanda R., Servi R.J., et al. Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: effect of hydrofluoroalkane-flunisolide. J Allergy Clin Immunol 116 (2005) 983-989