-
1
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
-
Artandi S, Chang S, Lee S, Alson S, Gottlieb G, Chin L, DePinho R. 2000. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406:641-645.
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.1
Chang, S.2
Lee, S.3
Alson, S.4
Gottlieb, G.5
Chin, L.6
DePinho, R.7
-
2
-
-
34948816005
-
The nature of telomere fusion and a definition of the critical telomere length in human cells
-
Capper R, Britt-Compton B, Tankimanova M, Rowson J, Letsolo B, Man S, Haughton M, Baird DM. 2007. The nature of telomere fusion and a definition of the critical telomere length in human cells. Genes Dev 21:2495-2508.
-
(2007)
Genes Dev
, vol.21
, pp. 2495-2508
-
-
Capper, R.1
Britt-Compton, B.2
Tankimanova, M.3
Rowson, J.4
Letsolo, B.5
Man, S.6
Haughton, M.7
Baird, D.M.8
-
3
-
-
0032700919
-
Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells
-
Cimini D, Tanzarella C, Degrassi F. 1999. Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells. Mutagenesis 14:563-568.
-
(1999)
Mutagenesis
, vol.14
, pp. 563-568
-
-
Cimini, D.1
Tanzarella, C.2
Degrassi, F.3
-
4
-
-
0037402984
-
Role of short telomeres in inducing preferential chromosomal aberrations in human ovarian surface epithelial cells: A combined telomere quantitative fluorescence in situ hybridization and whole-chromosome painting study
-
Deng W, Tsao S, Guan X, Lucas J, Cheung A. 2003. Role of short telomeres in inducing preferential chromosomal aberrations in human ovarian surface epithelial cells: A combined telomere quantitative fluorescence in situ hybridization and whole-chromosome painting study. Genes Chromosomes Cancer 37:92-97.
-
(2003)
Genes Chromosomes Cancer
, vol.37
, pp. 92-97
-
-
Deng, W.1
Tsao, S.2
Guan, X.3
Lucas, J.4
Cheung, A.5
-
5
-
-
10944222118
-
Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: Whole-genome evidence from multiple cell lines
-
Deng W, Tsao S, Guan X, Lucas J, Si H, Leung C, Mak P, Wang L, Cheung A. 2004. Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: Whole-genome evidence from multiple cell lines. Oncogene 23:9090-9101.
-
(2004)
Oncogene
, vol.23
, pp. 9090-9101
-
-
Deng, W.1
Tsao, S.2
Guan, X.3
Lucas, J.4
Si, H.5
Leung, C.6
Mak, P.7
Wang, L.8
Cheung, A.9
-
6
-
-
36248963247
-
Microtubule breakage is not a major mechanism for resolving end-to-end chromosome fusions generated by telomere dysfunction during the early process of immortalization
-
Deng W, Tsao S, Guan X, Cheung A. 2007. Microtubule breakage is not a major mechanism for resolving end-to-end chromosome fusions generated by telomere dysfunction during the early process of immortalization. Chromosoma 116:557-568.
-
(2007)
Chromosoma
, vol.116
, pp. 557-568
-
-
Deng, W.1
Tsao, S.2
Guan, X.3
Cheung, A.4
-
8
-
-
0034040855
-
Aneuploidy precedes and segregates with chemical carcinogenesis
-
Duesberg P, Li R, Rasnick D, Rausch C, Willer A, Kraemer A, Yerganian G, Hehlmann R. 2000. Aneuploidy precedes and segregates with chemical carcinogenesis. Cancer Genet Cytogenet 119:83-93.
-
(2000)
Cancer Genet Cytogenet
, vol.119
, pp. 83-93
-
-
Duesberg, P.1
Li, R.2
Rasnick, D.3
Rausch, C.4
Willer, A.5
Kraemer, A.6
Yerganian, G.7
Hehlmann, R.8
-
9
-
-
0036566036
-
Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres
-
Espejel S, Franco S, Rodríguez-Perales S, Bouffler S, Cigudosa J, Blasco M. 2002. Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres. EMBO J 21:2207-2219.
-
(2002)
EMBO J
, vol.21
, pp. 2207-2219
-
-
Espejel, S.1
Franco, S.2
Rodríguez-Perales, S.3
Bouffler, S.4
Cigudosa, J.5
Blasco, M.6
-
10
-
-
0037288474
-
Chromosome instability in cancer: How, when, and why?
-
Gisselsson D. 2003. Chromosome instability in cancer: How, when, and why? Adv Cancer Res 87:1-29.
-
(2003)
Adv Cancer Res
, vol.87
, pp. 1-29
-
-
Gisselsson, D.1
-
11
-
-
10944236160
-
Connecting mitotic instability and chromosome aberrations in cancer-Can telomeres bridge the gap?
-
Gisselsson D, Höglund M. 2005. Connecting mitotic instability and chromosome aberrations in cancer-Can telomeres bridge the gap? Semin Cancer Biol 15:13-23.
-
(2005)
Semin Cancer Biol
, vol.15
, pp. 13-23
-
-
Gisselsson, D.1
Höglund, M.2
-
12
-
-
0035940501
-
Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors
-
Gisselsson D, Jonson T, Petersén A, Strömbeck B, Dal Cin P, Höglund M, Mitelman F, Mertens F, Mandahl N. 2001. Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc Natl Acad Sci USA 98:12683-12688.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12683-12688
-
-
Gisselsson, D.1
Jonson, T.2
Petersén, A.3
Strömbeck, B.4
Dal Cin, P.5
Höglund, M.6
Mitelman, F.7
Mertens, F.8
Mandahl, N.9
-
13
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
Hemann M, Strong M, Hao L, Greider C. 2001. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107:67-77.
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.1
Strong, M.2
Hao, L.3
Greider, C.4
-
14
-
-
3543013739
-
Resolution of anaphase bridges in cancer cells
-
Hoffelder D, Luo L, Burke N, Watkins S, Gollin S, Saunders W. 2004. Resolution of anaphase bridges in cancer cells. Chromosoma 112:389-397.
-
(2004)
Chromosoma
, vol.112
, pp. 389-397
-
-
Hoffelder, D.1
Luo, L.2
Burke, N.3
Watkins, S.4
Gollin, S.5
Saunders, W.6
-
15
-
-
0029939848
-
Heterogeneity in telomere length of human chromosomes
-
Lansdorp P, Verwoerd N, van de Rijke F, Dragowska V, Little M, Dirks R, Raap A, Tanke H. 1996. Heterogeneity in telomere length of human chromosomes. Hum Mol Genet 5:685-691.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 685-691
-
-
Lansdorp, P.1
Verwoerd, N.2
van de Rijke, F.3
Dragowska, V.4
Little, M.5
Dirks, R.6
Raap, A.7
Tanke, H.8
-
16
-
-
4344680935
-
Human chromosomes with shorter telomeres and large heterochromatin regions have a higher frequency of acquired somatic cell aneuploidy
-
Leach N, Rehder C, Jensen K, Holt S, Jackson-Cook C. 2004. Human chromosomes with shorter telomeres and large heterochromatin regions have a higher frequency of acquired somatic cell aneuploidy. Mech Ageing Dev 125:563-573.
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 563-573
-
-
Leach, N.1
Rehder, C.2
Jensen, K.3
Holt, S.4
Jackson-Cook, C.5
-
17
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer C, Kinzler K, Vogelstein B. 1998. Genetic instabilities in human cancers. Nature 396:643-649.
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.2
Vogelstein, B.3
-
18
-
-
0034724312
-
Aneuploidy vs. gene mutation hypothesis of cancer: Recent study claims mutation but is found to support aneuploidy
-
Li R, Sonik A, Stindl R, Rasnick D, Duesberg P. 2000. Aneuploidy vs. gene mutation hypothesis of cancer: Recent study claims mutation but is found to support aneuploidy. Proc Natl Acad Sci USA 97:3236-3241.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3236-3241
-
-
Li, R.1
Sonik, A.2
Stindl, R.3
Rasnick, D.4
Duesberg, P.5
-
19
-
-
0036858415
-
DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line
-
Lo A, Sabatier L, Fouladi B, Pottier G, Ricoul M, Murnane J. 2002. DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. Neoplasia 4:531-538.
-
(2002)
Neoplasia
, vol.4
, pp. 531-538
-
-
Lo, A.1
Sabatier, L.2
Fouladi, B.3
Pottier, G.4
Ricoul, M.5
Murnane, J.6
-
20
-
-
36849042634
-
Telomere instability and cancer
-
Londoño-Vallejo J. 2008. Telomere instability and cancer. Biochimie 90:73-82.
-
(2008)
Biochimie
, vol.90
, pp. 73-82
-
-
Londoño-Vallejo, J.1
-
21
-
-
0038748324
-
Radiation-induced chromosome breaks in ataxia-telangiectasia cells remain open
-
Martín M, Genescà A, Latre L, Ribas M, Miró R, Egozcue J, Tusell L. 2003. Radiation-induced chromosome breaks in ataxia-telangiectasia cells remain open. Int J Radiat Biol 79:203-210.
-
(2003)
Int J Radiat Biol
, vol.79
, pp. 203-210
-
-
Martín, M.1
Genescà, A.2
Latre, L.3
Ribas, M.4
Miró, R.5
Egozcue, J.6
Tusell, L.7
-
22
-
-
0000839280
-
Telomere dysfunction provokes regional amplification and deletion in cancer genomes
-
O'Hagan R, Chang S, Maser R, Mohan R, Artandi S, Chin L, DePinho R. 2002. Telomere dysfunction provokes regional amplification and deletion in cancer genomes. Cancer Cell 2:149-155.
-
(2002)
Cancer Cell
, vol.2
, pp. 149-155
-
-
O'Hagan, R.1
Chang, S.2
Maser, R.3
Mohan, R.4
Artandi, S.5
Chin, L.6
DePinho, R.7
-
23
-
-
18644370262
-
Chromosomal instability in ulcerative colitis is related to telomere shortening
-
O'Sullivan J, Bronner M, Brentnall T, Finley J, Shen W, Emerson S, Emond M, Gollahon K, Moskovitz A, Crispin D, Potter JD, Rabinovitch PS. 2002. Chromosomal instability in ulcerative colitis is related to telomere shortening. Nat Genet 32:280-284.
-
(2002)
Nat Genet
, vol.32
, pp. 280-284
-
-
O'Sullivan, J.1
Bronner, M.2
Brentnall, T.3
Finley, J.4
Shen, W.5
Emerson, S.6
Emond, M.7
Gollahon, K.8
Moskovitz, A.9
Crispin, D.10
Potter, J.D.11
Rabinovitch, P.S.12
-
24
-
-
71549118520
-
-
Pampalona J, Soler D, Genescà A, Tusell L. 2010. Telomere dysfunction and chromosome structure modulate the contribution of individual chromosomes in abnormal nuclear morphologies. Mutat Res 683:16-22.
-
Pampalona J, Soler D, Genescà A, Tusell L. 2010. Telomere dysfunction and chromosome structure modulate the contribution of individual chromosomes in abnormal nuclear morphologies. Mutat Res 683:16-22.
-
-
-
-
25
-
-
2442695456
-
Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6
-
Plug-DeMaggio A, Sundsvold T, Wurscher M, Koop J, Klingelhutz A, McDougall J. 2004. Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6. Oncogene 23:3561-3571.
-
(2004)
Oncogene
, vol.23
, pp. 3561-3571
-
-
Plug-DeMaggio, A.1
Sundsvold, T.2
Wurscher, M.3
Koop, J.4
Klingelhutz, A.5
McDougall, J.6
-
26
-
-
0035102135
-
Non-disjunction and chromosome loss in gamma-irradiated human lymphocytes: A fluorescence in situ hybridization analysis using centromere-specific probes
-
Ponsa I, Barquinero J, Miró R, Egozcue J, Genescà A. 2001. Non-disjunction and chromosome loss in gamma-irradiated human lymphocytes: A fluorescence in situ hybridization analysis using centromere-specific probes. Radiat Res 155:424-431.
-
(2001)
Radiat Res
, vol.155
, pp. 424-431
-
-
Ponsa, I.1
Barquinero, J.2
Miró, R.3
Egozcue, J.4
Genescà, A.5
-
27
-
-
0033178240
-
Telomere length measurements using digital fluorescence microscopy
-
Poon SS, Martens UM, Ward RK, Lansdorp PM. 1999. Telomere length measurements using digital fluorescence microscopy. Cytometry 36:267-278.
-
(1999)
Cytometry
, vol.36
, pp. 267-278
-
-
Poon, S.S.1
Martens, U.M.2
Ward, R.K.3
Lansdorp, P.M.4
-
28
-
-
0035252089
-
Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
-
Romanov S, Kozakiewicz B, Holst C, Stampfer M, Haupt L, Tlsty T. 2001. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 409:633-637.
-
(2001)
Nature
, vol.409
, pp. 633-637
-
-
Romanov, S.1
Kozakiewicz, B.2
Holst, C.3
Stampfer, M.4
Haupt, L.5
Tlsty, T.6
-
29
-
-
0034978564
-
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
-
Rudolph K, Millard M, Bosenberg M, DePinho R. 2001. Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat Genet 28:155-159.
-
(2001)
Nat Genet
, vol.28
, pp. 155-159
-
-
Rudolph, K.1
Millard, M.2
Bosenberg, M.3
DePinho, R.4
-
30
-
-
0035110871
-
Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis
-
Shih I, Zhou W, Goodman S, Lengauer C, Kinzler K, Vogelstein B. 2001. Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis. Cancer Res 61:818-822.
-
(2001)
Cancer Res
, vol.61
, pp. 818-822
-
-
Shih, I.1
Zhou, W.2
Goodman, S.3
Lengauer, C.4
Kinzler, K.5
Vogelstein, B.6
-
31
-
-
9244260189
-
When, where and how the bridge breaks: Anaphase bridge breakage plays a crucial role in gene amplification and HSR generation
-
Shimizu N, Shingaki K, Kaneko-Sasaguri Y, Hashizume T, Kanda T. 2005. When, where and how the bridge breaks: Anaphase bridge breakage plays a crucial role in gene amplification and HSR generation. Exp Cell Res 302:233-243.
-
(2005)
Exp Cell Res
, vol.302
, pp. 233-243
-
-
Shimizu, N.1
Shingaki, K.2
Kaneko-Sasaguri, Y.3
Hashizume, T.4
Kanda, T.5
-
32
-
-
26944472376
-
Telomere dysfunction drives chromosomal instability in human mammary epithelial cells
-
Soler D, Genescà A, Arnedo G, Egozcue J, Tusell L. 2005. Telomere dysfunction drives chromosomal instability in human mammary epithelial cells. Genes Chromosomes Cancer 44:339-350.
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 339-350
-
-
Soler, D.1
Genescà, A.2
Arnedo, G.3
Egozcue, J.4
Tusell, L.5
-
33
-
-
17244367777
-
Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity
-
Stewé nius Y, Gorunova L, Jonson T, Larsson N, Höglund M, Mandahl N, Mertens F, Mitelman F, Gisselsson D. 2005. Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity. Proc Natl Acad Sci USA 102:5541-5546.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5541-5546
-
-
Stewé nius, Y.1
Gorunova, L.2
Jonson, T.3
Larsson, N.4
Höglund, M.5
Mandahl, N.6
Mertens, F.7
Mitelman, F.8
Gisselsson, D.9
-
34
-
-
61849142815
-
Telomere loss provokes multiple pathways to apoptosis and produces genomic instability in Drosophila melanogaster
-
Titen S, Golic K. 2008. Telomere loss provokes multiple pathways to apoptosis and produces genomic instability in Drosophila melanogaster. Genetics 180:1821-1832.
-
(2008)
Genetics
, vol.180
, pp. 1821-1832
-
-
Titen, S.1
Golic, K.2
-
35
-
-
59649128939
-
The number of dysfunctional telomeres in a cell: One amplifies; more than one translocate
-
Tusell L, Soler D, Agostini M, Pampalona J, Genescà A. 2008. The number of dysfunctional telomeres in a cell: One amplifies; more than one translocate. Cytogenet Genome Res 122:315-325.
-
(2008)
Cytogenet Genome Res
, vol.122
, pp. 315-325
-
-
Tusell, L.1
Soler, D.2
Agostini, M.3
Pampalona, J.4
Genescà, A.5
-
36
-
-
0141731307
-
Aneuploidy and telomere attrition are independent determinants of crisis in SV40-transformed epithelial cells
-
Velicescu M, Yu J, Herbert B, Shay J, Granada E, Dubeau L. 2003. Aneuploidy and telomere attrition are independent determinants of crisis in SV40-transformed epithelial cells. Cancer Res 63:5813-5820.
-
(2003)
Cancer Res
, vol.63
, pp. 5813-5820
-
-
Velicescu, M.1
Yu, J.2
Herbert, B.3
Shay, J.4
Granada, E.5
Dubeau, L.6
|