CD4 + T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease

Journal of Clinical Investigation

Volumn 122, Issue 5, 2012, Pages 1816-1831

  De Luca, Antonella ^a   Iannitti, Rossana G ^a   Bozza, Silvia ^a   Beau, Remi ^b   Casagrande, Andrea ^a,c   D'Angelo, Carmen ^a   Moretti, Silvia ^a   Cunha, Cristina ^a   Giovannini, Gloria ^a   Massi Benedetti, Cristina ^a   Carvalho, Agostinho ^a,d,e   Boon, Louis ^f   Latgé, Jean Paul ^b   Romani, Luigina ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b INSTITUT PASTEUR   (France)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d UNIVERSITY OF MINHO   (Portugal)

^e UNIVERSITY OF MINHO   (Portugal)

^f BIOCEROS   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; DENDRITIC CELL VACCINE; FUNGUS ANTIGEN; FUNGUS VACCINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN CRF1P; PROTEIN GEL1P; PROTEIN PEP1P; PROTEIN RAB14; RAB PROTEIN; RECOMBINANT ANTIGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; UNCLASSIFIED DRUG;

ALKALINIZATION; ALLOGENEIC RESTRICTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLOSIS; ASPERGILLUS; ASPERGILLUS FUMIGATUS; AUTOPHAGY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PH; CELLULAR IMMUNITY; CHRONIC GRANULOMATOUS DISEASE; CONIDIUM; CONTROLLED STUDY; CROSS PRESENTATION; DENDRITIC CELL; ENDOSOME; EXPERIMENTAL MODEL; FEMALE; FLOW CYTOMETRY; INNATE IMMUNITY; LYSOSOME; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; VACCINATION;

ADAPTIVE IMMUNITY; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, FUNGAL; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CROSS-PRIMING; DENDRITIC CELLS; DNA HELICASES; FEMALE; GRANULOMATOUS DISEASE, CHRONIC; LUNG; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NADPH OXIDASE; OLIGODEOXYRIBONUCLEOTIDES; PHAGOCYTOSIS; SIGNAL TRANSDUCTION; SPORES, FUNGAL; TOLL-LIKE RECEPTORS; VACCINATION;

EID: 84860544922     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI60862     Document Type: Article

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