Novel MT1-MMP small-molecule inhibitors based on insights into hemopexin domain function in tumor growth

Cancer Research

Volumn 72, Issue 9, 2012, Pages 2339-2349

  Remacle, Albert G ^a   Golubkov, Vladislav S ^a   Shiryaev, Sergey A ^a   Dahl, Russell ^a   Stebbins, John L ^a   Chernov, Andrei V ^a   Cheltsov, Anton V ^a   Pellecchia, Maurizio ^a   Strongin, Alex Y ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOPEXIN; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE INHIBITOR; MEMBRANE TYPE 1 MATRIX METALLOPROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOGENESIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; CELL GROWTH PROCESSES; FEMALE; HEMOPEXIN; HUMANS; MATRIX METALLOPROTEINASE 14; MICE; MICE, INBRED BALB C; MICE, NUDE; MODELS, MOLECULAR; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84860523112     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-4149     Document Type: Article

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