The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: Crystal structure and biological functions

Journal of Biological Chemistry

Volumn 286, Issue 9, 2011, Pages 7587-7600

  Tochowicz, Anna ^a,e   Goettig, Peter ^a,f   Evans, Richard ^b   Visse, Robert ^b   Shitomi, Yasuyuki ^b   Palmisano, Ralf ^b,g   Ito, Noriko ^b   Richter, Klaus ^c   Maskos, Klaus ^a,h   Franke, Daniel ^d   Svergun, Dmitri ^d   Nagase, Hideaki ^b   Bode, Wolfram ^a   Itoh, Yoshifumi ^b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d DESY   (Germany)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF SALZBURG   (Austria)

^g UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^h PROTEROS BIOSTRUCTURES GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL FUNCTIONS; CELL MIGRATION; CELL SURFACES; COLLAGEN MATRICES; DEPENDENT FUNCTIONS; DIMER INTERFACE; FULL-LENGTH ENZYMES; GELATIN FILM; HEMOPEXIN; HOMODIMERIZATION; INDEPENDENT FUNCTIONS; MEMBRANE TYPE-1 MATRIX METALLOPROTEINASE; MOLECULAR BASIS; STRUCTURAL BASIS;

AMINO ACIDS; CELL MEMBRANES; COLLAGEN; CRYSTAL STRUCTURE; CYTOLOGY; DEGRADATION; DIMERIZATION; TWO DIMENSIONAL;

DIMERS;

COLLAGEN; GELATINASE A; HEMOPEXIN; MATRIX METALLOPROTEINASE 14;

ANIMAL CELL; ARTICLE; CELL INVASION; CELL MIGRATION; CELL SURFACE; COLLAGEN DEGRADATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; CRYSTALLOGRAPHY; DIMERIZATION; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; HELA CELLS; HEMOPEXIN; HUMANS; MATRIX METALLOPROTEINASE 14; MEMBRANE PROTEINS; MUTAGENESIS; PROTEIN STRUCTURE, TERTIARY; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79953224829     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.178434     Document Type: Article

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