Intradomain cleavage of inhibitory prodomain is essential to protumorigenic function of membrane type-1 matrix metalloproteinase (MT1-MMP) in vivo

Journal of Biological Chemistry

Volumn 286, Issue 39, 2011, Pages 34215-34223

  Golubkov, Vladislav S ^a   Chernov, Andrei V ^a   Strongin, Alex Y ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASEMENT MEMBRANE; BREAST CANCER XENOGRAFTS; CANCER CELLS; CELL-BASED; CLEAVAGE SITES; CULTURED CELL; EXTRACELLULAR MATRICES; IN-VIVO; INTRA-DOMAIN; MEMBRANE TYPE-1 MATRIX METALLOPROTEINASE; N-TERMINALS; ORTHOTOPIC; PERICELLULAR PROTEOLYSIS; POTENT INHIBITOR; TRANSCRIPTIONAL PROFILING; TUMOR XENOGRAFTS; WILD TYPES;

CELL MEMBRANES; DISEASES; ENZYME ACTIVITY; ENZYME INHIBITION; TISSUE;

BIOSENSORS;

MATRIX METALLOPROTEINASE 14;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSENSOR; BREAST CANCER; CANCER CELL CULTURE; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR CLONING; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; TUMOR XENOGRAFT; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; ENZYME ACTIVATION; FEMALE; FURIN; HUMANS; MATRIX METALLOPROTEINASE 14; MICE; MICE, NUDE; MUTATION, MISSENSE; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS;

MUS;

EID: 80053196585     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.264036     Document Type: Article

References (36)

1. Friedl, P., and Wolf, K. (2009) Cancer Metastasis Rev. 28, 129-135
2. Egeblad, M., Nakasone, E. S., and Werb, Z. (2010) Dev. Cell 18, 884-901
3. Murphy, G., and Nagase, H. (2011) FEBS J. 278, 2-15
4. Rowe, R. G., and Weiss, S. J. (2009) Annu. Rev. Cell Dev. Biol. 25, 567-595
5. Egeblad, M., and Werb, Z. (2002) Nat. Rev. Cancer 2, 161-174
6. Nagase, H., Visse, R., and Murphy, G. (2006) Cardiovasc. Res. 69, 562-573
7. Sohail, A., Sun, Q., Zhao, H., Bernardo, M. M., Cho, J. A., and Fridman, R. (2008) Cancer Metastasis Rev. 27, 289-302
8. Sabeh, F., Shimizu-Hirota, R., and Weiss, S. J. (2009) J. Cell Biol. 185, 11-19
9. Ota, I., Li, X. Y., Hu, Y., and Weiss, S. J. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 20318-20323
10. Szabova, L., Chrysovergis, K., Yamada, S. S., and Holmbeck, K. (2008) Oncogene 27, 3274-3281
11. Seiki, M. (2003) Cancer Lett. 194, 1-11
12. Hotary, K. B., Allen, E. D., Brooks, P. C., Datta, N. S., Long, M. W., and Weiss, S. J. (2003) Cell 114, 33-45
13. Strongin, A. Y., Collier, I., Bannikov, G., Marmer, B. L., Grant, G. A., and Goldberg, G. I. (1995) J. Biol. Chem. 270, 5331-5338
14. Strongin, A. Y. (2010) Biochim. Biophys. Acta 1803, 133-141
15. Rowe, R. G., and Weiss, S. J. (2008) Trends Cell Biol. 18, 560-574
16. Nagase, H., and Woessner, J. F., Jr. (1999) J. Biol. Chem. 274, 21491-21494
17. Pei, D., and Weiss, S. J. (1995) Nature 375, 244-247
18. Seidah, N. G., Mayer, G., Zaid, A., Rousselet, E., Nassoury, N., Poirier, S., Essalmani, R., and Prat, A. (2008) Int. J. Biochem. Cell Biol. 40, 1111-1125
19. Golubkov, V. S., Chekanov, A. V., Shiryaev, S. A., Aleshin, A. E., Ratnikov, B. I., Gawlik, K., Radichev, I., Motamedchaboki, K., Smith, J. W., and Strongin, A. Y. (2007) J. Biol. Chem. 282, 36283-36291
20. Golubkov, V. S., Cieplak, P., Chekanov, A. V., Ratnikov, B. I., Aleshin, A. E., Golubkova, N. V., Postnova, T. I., Radichev, I. A., Rozanov, D. V., Zhu, W., Motamedchaboki, K., and Strongin, A. Y. (2010) J. Biol. Chem. 285, 27726-27736
21. Pei, D., and Weiss, S. J. (1996) J. Biol. Chem. 271, 9135-9140
22. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E., and Seiki, M. (1994) Nature 370, 61-65
23. Chambers, A. F. (2009) Cancer Res. 69, 5292-5293
24. Golubkov, V. S., Chekanov, A. V., Cieplak, P., Aleshin, A. E., Chernov, A. V., Zhu, W., Radichev, I. A., Zhang, D., Dong, P. D., and Strongin, A. Y. (2010) J. Biol. Chem. 285, 35740-35749
25. Campbell, R. E., Tour, O., Palmer, A. E., Steinbach, P. A., Baird, G. S., Zacharias, D. A., and Tsien, R. Y. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 7877-7882
26. Rozanov, D. V., Deryugina, E. I., Ratnikov, B. I., Monosov, E. Z., Marchenko, G. N., Quigley, J. P., and Strongin, A. Y. (2001) J. Biol. Chem. 276, 25705-25714
27. Hernandez-Barrantes, S., Toth, M., Bernardo, M. M., Yurkova, M., Gervasi, D. C., Raz, Y., Sang, Q. A., and Fridman, R. (2000) J. Biol. Chem. 275, 12080-12089
28. Remacle, A. G., Chekanov, A. V., Golubkov, V. S., Savinov, A. Y., Rozanov, D. V., and Strongin, A. Y. (2006) J. Biol. Chem. 281, 16897-16905
29. Chernov, A. V., Baranovskaya, S., Golubkov, V. S., Wakeman, D. R., Snyder, E. Y., Williams, R., and Strongin, A. Y. (2010) J. Biol. Chem. 285, 19647-19659
30. Fantozzi, A., and Christofori, G. (2006) Breast Cancer Res. 8, 212
31. Grum-Schwensen, B., Klingelhöfer, J., Grigorian, M., Almholt, K., Nielsen, B. S., Lukanidin, E., and Ambartsumian, N. (2010) Cancer Res. 70, 936-947
32. Soulié, P., Carrozzino, F., Pepper, M. S., Strongin, A. Y., Poupon, M. F., and Montesano, R. (2005) Oncogene 24, 1689-1697
33. Golubkov, V. S., Chekanov, A. V., Savinov, A. Y., Rozanov, D. V., Golubkova, N. V., and Strongin, A. Y. (2006) Cancer Res. 66, 10460-10465
34. Thomas, G. (2002) Nat. Rev. Mol. Cell Biol. 3, 753-766
35. Deryugina, E. I., Ratnikov, B., Monosov, E., Postnova, T. I., DiScipio, R., Smith, J. W., and Strongin, A. Y. (2001) Exp. Cell Res. 263, 209-223
36. D'Alessio, S., Ferrari, G., Cinnante, K., Scheerer, W., Galloway, A. C., Roses, D. F., Rozanov, D. V., Remacle, A. G., Oh, E. S., Shiryaev, S. A., Strongin, A. Y., Pintucci, G., and Mignatti, P. (2008) J. Biol. Chem. 283, 87-99