Astragaloside II induces osteogenic activities of osteoblasts through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways

International Journal of Molecular Medicine

Volumn 29, Issue 6, 2012, Pages 1090-1098

  Kong, Xiang He ^a   Niu, Yin Bo ^a   Song, Xiao Mei ^c   Zhao, Dong Dong ^c   Wang, Juan ^a   Wu, Xiang Long ^a   Zhang, Rong ^b   Mei, Qi Bing ^a,b  

^a NORTHWESTERN POLYTECHNICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c SHAANXI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Astragaloside II; Bone morphogenetic protein 2; Mitogen activated protein kinases; Osteoblasts; Osteogenic activities; Smad1 5 8

Indexed keywords

ASTRAGALOSIDE II; ASTRAGALUS EXTRACT; BONE MORPHOGENETIC PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; NATURAL PRODUCT; SAPONIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTRAGALUS PLANT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CHEMICAL STRUCTURE; CHINESE MEDICINE; CONTROLLED STUDY; ENZYME ACTIVATION; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; OSTEOPOROSIS; PLANT ROOT; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TRADITIONAL MEDICINE;

ANIMALS; ANIMALS, NEWBORN; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; OSTEOBLASTS; OSTEOGENESIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS; SIGNAL TRANSDUCTION; SMAD PROTEINS; UP-REGULATION;

EID: 84860515295     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.941     Document Type: Article

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