메뉴 건너뛰기




Volumn 5, Issue 5, 2003, Pages 214-222

A review of anabolic therapies for osteoporosis

Author keywords

Anabolic; Bone morphogenic protein 2 (BMP 2); Bone morphogenic protein 7; Parathyroid hormone hPTH (1 84); Parathyroid hormone rhPTH (1 34)

Indexed keywords

ALENDRONIC ACID; ANABOLIC AGENT; ATORVASTATIN; BISPHOSPHONIC ACID DERIVATIVE; BONE MORPHOGENETIC PROTEIN 2; CERIVASTATIN; ESTROGEN; ETIDRONIC ACID; FIBROBLAST GROWTH FACTOR; FLUORIDE; GROWTH FACTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; MEVINOLIN; NITRIC OXIDE SYNTHASE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOGENIC PROTEIN 1; PARATHYROID HORMONE; PARATHYROID HORMONE DERIVATIVE; PITAVASTATIN; PLACEBO; RALOXIFENE; RECOMBINANT GROWTH HORMONE; RECOMBINANT PROTEIN; SIMVASTATIN; SOMATOMEDIN C; STRONTIUM; TRANSFORMING GROWTH FACTOR BETA; UNINDEXED DRUG; VASCULOTROPIN;

EID: 0141857862     PISSN: 14786354     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (85)

References (82)
  • 1
    • 0002734325 scopus 로고    scopus 로고
    • Introduction to normal bone physiology and pathophysiology
    • 2nd edition. Edited by Marcus R, Feldman D, Kelsey J. San Francisco, CA: Academic Press
    • Lee CA, Einhorn TA: Introduction to normal bone physiology and pathophysiology. In Osteoporosis. 2nd edition. Edited by Marcus R, Feldman D, Kelsey J. San Francisco, CA: Academic Press; 2001:3-19.
    • (2001) Osteoporosis , pp. 3-19
    • Lee, C.A.1    Einhorn, T.A.2
  • 6
    • 0037111794 scopus 로고    scopus 로고
    • Parathyroid hormone for treatment of osteoporosis
    • Crandall C: Parathyroid hormone for treatment of osteoporosis. Arch Intern Med 2002, 162:2297-2309.
    • (2002) Arch. Intern. Med. , vol.162 , pp. 2297-2309
    • Crandall, C.1
  • 7
    • 84944478385 scopus 로고
    • Hyperparathyroidism: A common and polymorphic condition illustrated by seventeen proven cases from one clinic
    • Albright F, Aub JC, Bauer W: Hyperparathyroidism: a common and polymorphic condition illustrated by seventeen proven cases from one clinic. JAMA 1934, 102:1276-1287.
    • (1934) JAMA , vol.102 , pp. 1276-1287
    • Albright, F.1    Aub, J.C.2    Bauer, W.3
  • 9
    • 0023915687 scopus 로고
    • Human parathyroid hormone (1-34) increases bone mass in ovariectomized and orchidectomized rats
    • Hock JM, Gera I, Fonseca J, Raisz LG: Human parathyroid hormone (1-34) increases bone mass in ovariectomized and orchidectomized rats. Endocrinology 1988, 122:2899-2904.
    • (1988) Endocrinology , vol.122 , pp. 2899-2904
    • Hock, J.M.1    Gera, I.2    Fonseca, J.3    Raisz, L.G.4
  • 10
    • 0029130188 scopus 로고    scopus 로고
    • Intermittent treatment with human parathyroid hormone (hPTH 1-34) increased trabecular bone mass but not connectivity in osteopenic rats
    • Lane NE, Thompson JM, Strewler G, Kinney JH: Intermittent treatment with human parathyroid hormone (hPTH 1-34) increased trabecular bone mass but not connectivity in osteopenic rats. J Bone Miner Res 1996, 10:1470-1477.
    • (1996) J. Bone Miner. Res. , vol.10 , pp. 1470-1477
    • Lane, N.E.1    Thompson, J.M.2    Strewler, G.3    Kinney, J.H.4
  • 13
    • 0037946799 scopus 로고    scopus 로고
    • How to grow bone to treat osteoporosis and mend fractures
    • Whitfield JF: How to grow bone to treat osteoporosis and mend fractures. Curr Rheumatol Rep 2003, 5:45-56.
    • (2003) Curr. Rheumatol. Rep. , vol.5 , pp. 45-56
    • Whitfield, J.F.1
  • 14
    • 0141785434 scopus 로고    scopus 로고
    • Both hPTH (1-34) increase trabecular bone mass in osteopenic rats however they have different effects on trabecular bone structure
    • in press
    • Lane NE, Yao W, Kinney JH, Modin G, Baloosh M, Wronski TJ: Both hPTH (1-34) increase trabecular bone mass in osteopenic rats however they have different effects on trabecular bone structure. J Bone Min Res 2003, in press.
    • (2003) J. Bone Min. Res.
    • Lane, N.E.1    Yao, W.2    Kinney, J.H.3    Modin, G.4    Baloosh, M.5    Wronski, T.J.6
  • 15
    • 25044468814 scopus 로고    scopus 로고
    • Association of serum RANKL and OPG levels with other biochemical markers of bone turnover in glucocorticoid-induced osteoporosis patients treated with hPTH (1-34)
    • [abstract]
    • Lane N, Yao W, Arnaud C: Association of serum RANKL and OPG levels with other biochemical markers of bone turnover in glucocorticoid-induced osteoporosis patients treated with hPTH (1-34) [abstract]. J Bone Miner Res 2002, Suppl 1:F366.
    • (2002) J. Bone Miner. Res. , Issue.SUPPL. 1
    • Lane, N.1    Yao, W.2    Arnaud, C.3
  • 16
    • 0141450555 scopus 로고    scopus 로고
    • Changes in serum RANKL, OPG and IL-6 during hPTH (1-34) administration in patients with glucocorticoid induced osteoporosis
    • in press
    • Lane NE, Yao W, Arnaud CD: Changes in serum RANKL, OPG and IL-6 during hPTH (1-34) administration in patients with glucocorticoid induced osteoporosis. J Bone Miner Res 2003, Suppl 1: in press.
    • (2003) J. Bone Miner. Res. , Issue.SUPPL. 1
    • Lane, N.E.1    Yao, W.2    Arnaud, C.D.3
  • 18
    • 17544368686 scopus 로고    scopus 로고
    • Stimulation of parathyroid hormone of interleukin-6 and leukemia inhibitory factor expression in osteoblasts is an immediate-early gene response induced by cAMP signal transduction
    • Greenfield EM, Horowitz Lavish SA: Stimulation of parathyroid hormone of interleukin-6 and leukemia inhibitory factor expression in osteoblasts is an immediate-early gene response induced by cAMP signal transduction. J Biol Chem 1996, 271:10984-10989.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10984-10989
    • Greenfield, E.M.1    Horowitz Lavish, S.A.2
  • 19
    • 0037073707 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates receptor activator of NFkB ligand and inhibits osteoprotegrin expression via protein kinase A activation of cAMP-response element binding protein
    • Fu Q, Jilka RL, Manolagas SC, O'Brien CA: Parathyroid hormone stimulates receptor activator of NFkB ligand and inhibits osteoprotegrin expression via protein kinase A activation of cAMP-response element binding protein. J Biol Chem 2002, 277:48868-48875.
    • (2002) J. Biol. Chem. , vol.277 , pp. 48868-48875
    • Fu, Q.1    Jilka, R.L.2    Manolagas, S.C.3    O'Brien, C.A.4
  • 20
    • 0033305046 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates TRANCE and inhibits osteoprotegrin messenger ribonucleic acid expression with osteoclast-like cell formation
    • Lee S-K, Lorenzo JA: Parathyroid hormone stimulates TRANCE and inhibits osteoprotegrin messenger ribonucleic acid expression with osteoclast-like cell formation. Endocrinology 1999, 140:3552-3561.
    • (1999) Endocrinology , vol.140 , pp. 3552-3561
    • Lee, S.-K.1    Lorenzo, J.A.2
  • 21
    • 0035158179 scopus 로고    scopus 로고
    • Intermittently administered human parathyroid hormone (1-34) treatment increases intracortical bone turnover and porosity without reducing bone strength in the humerus of ovariectomized cynomolgus monkeys
    • Burr DB, Hirano T, Turner CH, Hotchkiss C, Brommage R, Hock JM: Intermittently administered human parathyroid hormone (1-34) treatment increases intracortical bone turnover and porosity without reducing bone strength in the humerus of ovariectomized cynomolgus monkeys. J Bone Miner Res 2001, 16:157-165.
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 157-165
    • Burr, D.B.1    Hirano, T.2    Turner, C.H.3    Hotchkiss, C.4    Brommage, R.5    Hock, J.M.6
  • 24
    • 0030804947 scopus 로고    scopus 로고
    • Randomized controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis
    • Lindsay R, Nieves J, Formica C, Henneman E, Woelfert L, Shen V, Dempster D, Cosman F: Randomized controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis. Lancet 1997, 350:550-555.
    • (1997) Lancet , vol.350 , pp. 550-555
    • Lindsay, R.1    Nieves, J.2    Formica, C.3    Henneman, E.4    Woelfert, L.5    Shen, V.6    Dempster, D.7    Cosman, F.8
  • 25
    • 0001401316 scopus 로고    scopus 로고
    • Parathyroid hormone 1-34 (hPTH 1-34) and estrogen produce dramatic bone density increase in postmenopausal osteoporosis-results from a placebo-controlled randomized trial
    • [abstract]
    • Roe E, Sanchez S, del puerto G, et al. Parathyroid hormone 1-34 (hPTH 1-34) and estrogen produce dramatic bone density increase in postmenopausal osteoporosis-results from a placebo-controlled randomized trial [abstract]. J Bone Miner Res, 1999, Suppl 1:S137.
    • (1999) J. Bone Miner. Res. , Issue.SUPPL. 1
    • Roe, E.1    Sanchez, S.2    del puerto, G.3
  • 26
    • 0001401315 scopus 로고    scopus 로고
    • PTH effect in the femur: Envelope-specific responses by 3DQCT in postmenopausal women
    • [abstract]
    • Cann C, Roe EB, Sanchez SD, et al.: PTH effect in the femur: envelope-specific responses by 3DQCT in postmenopausal women [abstract]. J Bone Miner Res 1999, Suppl 1:S137.
    • (1999) J. Bone Miner. Res. , Issue.SUPPL. 1
    • Cann, C.1    Roe, E.B.2    Sanchez, S.D.3
  • 28
    • 0001961747 scopus 로고    scopus 로고
    • PTH and bisphosphonates in the treatment of osteoporosis: Design of the PTH and alendronate (PATH) trial
    • [abstract] In ASBMR 23rd annual meeting
    • Black DM, Rosen C, Greenspan S, Ensrud K, Bilezikian J, McGowan J: PTH and bisphosphonates in the treatment of osteoporosis: design of the PTH and alendronate (PATH) trial [abstract]. In ASBMR 23rd annual meeting, 2001:5287.
    • (2001) , pp. 5287
    • Black, D.M.1    Rosen, C.2    Greenspan, S.3    Ensrud, K.4    Bilezikian, J.5    McGowan, J.6
  • 29
    • 0141450554 scopus 로고    scopus 로고
    • Effects of parathyroid hormone, alendronate or both on bone mineral density in osteoporotic men
    • [abstract]
    • Finkelstein JS, Hayes A, Rao A, Neer RM: Effects of parathyroid hormone, alendronate or both on bone mineral density in osteoporotic men [abstract]. J Bone Miner Res 2002, Suppl 1:1007.
    • (2002) J. Bone Miner. Res. , Issue.SUPPL. 1 , pp. 1007
    • Finkelstein, J.S.1    Hayes, A.2    Rao, A.3    Neer, R.M.4
  • 30
    • 0141663503 scopus 로고    scopus 로고
    • Effects of parathyroid hormone, alendronate, or both on bone density in osteoporotic postmenopausal women
    • [abstract]
    • Neer R, Hayes A, Rao A, Finkelstein J: Effects of parathyroid hormone, alendronate, or both on bone density in osteoporotic postmenopausal women [abstract]. J Bone Miner Res 2002, Suppl 1:1039.
    • (2002) J. Bone Miner. Res. , Issue.SUPPL. 1 , pp. 1039
    • Neer, R.1    Hayes, A.2    Rao, A.3    Finkelstein, J.4
  • 31
    • 0141562111 scopus 로고    scopus 로고
    • Early response of bone turnover markers and bone mineral density to teriparatide (rhPTH 1-34) in postmenopausal women previously treated with an anti-resorptive agent
    • [abstract]
    • Ettinger B, San Martin JA, Crans G, Pavo I: Early response of bone turnover markers and bone mineral density to teriparatide (rhPTH 1-34) in postmenopausal women previously treated with an anti-resorptive agent [abstract]. J Bone Miner Res 2002, Suppl 1:1136.
    • (2002) J. Bone Miner. Res. , Issue.SUPPL. 1 , pp. 1136
    • Ettinger, B.1    San Martin, J.A.2    Crans, G.3    Pavo, I.4
  • 32
    • 0037323386 scopus 로고    scopus 로고
    • Short-term, high-dose parathyroid hormone-related protein as a skeletal anabolic agent for the treatment of postmenopausal osteoporosis
    • Horwitz M, Stewart A, Greenspan SL: Short-term, high-dose parathyroid hormone-related protein as a skeletal anabolic agent for the treatment of postmenopausal osteoporosis. J Clin Endocrinol Metab, 2003, 88:569-575.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 569-575
    • Horwitz, M.1    Stewart, A.2    Greenspan, S.L.3
  • 33
    • 0001965181 scopus 로고    scopus 로고
    • Growth hormone, insulin-like growth factors. Potential applications and limitations in the management of osteoporosis
    • 2nd edition. Edited by Marcus R, Feldman D, Kelsey J. San Francisco, CA: Academic Press
    • Wuster C, Rosen C: Growth hormone, insulin-like growth factors. Potential applications and limitations in the management of osteoporosis. In Osteoporosis. 2nd edition. Edited by Marcus R, Feldman D, Kelsey J. San Francisco, CA: Academic Press; 2001: 747-767.
    • (2001) Osteoporosis , pp. 747-767
    • Wuster, C.1    Rosen, C.2
  • 37
    • 0037338638 scopus 로고    scopus 로고
    • From mouse to man: Redefining the role of insulin-like growth factor-I in the acquisition of bone mass
    • Yakar S, Rosen CJ: From mouse to man: redefining the role of insulin-like growth factor-I in the acquisition of bone mass. Proc Soc Exp Biol Med 2003, 228:245-252.
    • (2003) Proc. Soc. Exp. Biol. Med. , vol.228 , pp. 245-252
    • Yakar, S.1    Rosen, C.J.2
  • 39
    • 0033531765 scopus 로고    scopus 로고
    • Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
    • Ma J, Pollak MN, Giovannucci E, Chan JM, Tao Y, Hennekens CH, Stampfer MJ: Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 1999, 91:620-625.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 620-625
    • Ma, J.1    Pollak, M.N.2    Giovannucci, E.3    Chan, J.M.4    Tao, Y.5    Hennekens, C.H.6    Stampfer, M.J.7
  • 41
    • 0037370988 scopus 로고    scopus 로고
    • Growth hormone increases bone mineral content in post-menopausal osteoporosis: A randomized placebo-controlled trial
    • Landin-Wilhelmsen K, Nilsson A, Bosaeus I, Bengtsson, B: Growth hormone increases bone mineral content in post-menopausal osteoporosis: a randomized placebo-controlled trial. J Bone Miner Res 2003, 18:393-405.
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 393-405
    • Landin-Wilhelmsen, K.1    Nilsson, A.2    Bosaeus, I.3    Bengtsson, B.4
  • 42
    • 0035992777 scopus 로고    scopus 로고
    • Strontium ranelate in osteoporosis
    • Reginster JY: Strontium ranelate in osteoporosis. Curr Pharm Des 2002, 8:1907-1916.
    • (2002) Curr. Pharm. Des. , vol.8 , pp. 1907-1916
    • Reginster, J.Y.1
  • 43
    • 0027316220 scopus 로고
    • An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats
    • Marie PJ, Hott M, Modrowski D, De Pollack C, Guillemain J, Deloffre P, Tsouderos Y: An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats. J Bone Miner Res 1993, 8:607-615.
    • (1993) J. Bone Miner. Res. , vol.8 , pp. 607-615
    • Marie, P.J.1    Hott, M.2    Modrowski, D.3    De Pollack, C.4    Guillemain, J.5    Deloffre, P.6    Tsouderos, Y.7
  • 44
    • 0036922499 scopus 로고    scopus 로고
    • Prevention of early postmenopausal bone loss by strontium ranelate: The randomized, two-year, double-masked, dose-ranging, placebo-controlled PREVOS trial
    • Reginster JY, Deroisy R, Dougados M, Jupsin I, Colette J, Roux C: Prevention of early postmenopausal bone loss by strontium ranelate: the randomized, two-year, double-masked, dose-ranging, placebo-controlled PREVOS trial. Osteoporos Int 2002, 13:925-931.
    • (2002) Osteoporos. Int. , vol.13 , pp. 925-931
    • Reginster, J.Y.1    Deroisy, R.2    Dougados, M.3    Jupsin, I.4    Colette, J.5    Roux, C.6
  • 45
    • 10744233106 scopus 로고    scopus 로고
    • Strontium ranelate: A new effective antiosteoporotic treatment reducing the incidence of vertebral and non vertebral fractures in postmenopausal women with osteoporosis
    • In International Osteoporosis Society meeting. June Osaka, Japan, in press
    • Reginster JY, Hoszowski K, Roces Varela A, Balogh A, Clements M, Fiore C, Cormier C, Schmidt WE, Jensen JB, Prince R, Raeman F, Rizzoli R, Meunier PJ: Strontium ranelate: a new effective antiosteoporotic treatment reducing the incidence of vertebral and non vertebral fractures in postmenopausal women with osteoporosis. In International Osteoporosis Society meeting. June 2003; Osaka, Japan, in press.
    • (2003)
    • Reginster, J.Y.1    Hoszowski, K.2    Roces Varela, A.3    Balogh, A.4    Clements, M.5    Fiore, C.6    Cormier, C.7    Schmidt, W.E.8    Jensen, J.B.9    Prince, R.10    Raeman, F.11    Rizzoli, R.12    Meunier, P.J.13
  • 46
    • 0141834679 scopus 로고    scopus 로고
    • Design and methodology of the phase 3 trials for the clinical development of strontium ranelate in the treatment of women with postmenopausal osteoporosis
    • Meunier PJ, Reginster JY: Design and methodology of the phase 3 trials for the clinical development of strontium ranelate in the treatment of women with postmenopausal osteoporosis. Osteoporos Int 2003, Suppl 3:66-76.
    • (2003) Osteoporos. Int. , Issue.SUPPL. 3 , pp. 66-76
    • Meunier, P.J.1    Reginster, J.Y.2
  • 48
    • 0012527150 scopus 로고    scopus 로고
    • Statins stimulate bone formation by enhancing eNOS expression
    • [abstract]
    • Garrett IR, Gutierrez G, Chen D, et al.: Statins stimulate bone formation by enhancing eNOS expression [abstract]. J Bone Miner Res 2001, 16:S141.
    • (2001) J. Bone Miner. Res. , vol.16
    • Garrett, I.R.1    Gutierrez, G.2    Chen, D.3
  • 51
    • 0028783928 scopus 로고
    • Lipid-clearing agents in steroid-induced osteoporosis
    • Wang GJ, Chung KC, Shen WJ: Lipid-clearing agents in steroid-induced osteoporosis. J Formos Med Assoc 1995, 94:589-592.
    • (1995) J. Formos. Med. Assoc. , vol.94 , pp. 589-592
    • Wang, G.J.1    Chung, K.C.2    Shen, W.J.3
  • 52
    • 0001307140 scopus 로고    scopus 로고
    • Effects of short-term cerivastatin on bone turnover
    • [abstract]
    • Cosman F, Nieves J, Zion M, et al.: Effects of short-term cerivastatin on bone turnover [abstract]. J Bone Miner Res 2001, 16:S29.
    • (2001) J. Bone Miner. Res. , vol.16
    • Cosman, F.1    Nieves, J.2    Zion, M.3
  • 54
    • 0042348740 scopus 로고    scopus 로고
    • HMG CoA reductase inhibitors and the skeleton: A comprehensive review
    • Bauer DC: HMG CoA reductase inhibitors and the skeleton: a comprehensive review. Osteoporos Int 2003, 4:273-282
    • (2003) Osteoporos. Int. , vol.4 , pp. 273-282
    • Bauer, D.C.1
  • 55
    • 0035901052 scopus 로고    scopus 로고
    • Effect of pravastatin on frequency of fracture in the LIPID study: Secondary analysis of a randomised controlled trial. Long-term Intervention with Pravastatin in Ischaemic Disease
    • Reid IR, Hague W, Emberson J, Baker J, Tonkin A, Hunt D, MacMahon S, Sharpe N: Effect of pravastatin on frequency of fracture in the LIPID study: secondary analysis of a randomised controlled trial. Long-term Intervention with Pravastatin in Ischaemic Disease. Lancet 2001, 357:509-512.
    • (2001) Lancet , vol.357 , pp. 509-512
    • Reid, I.R.1    Hague, W.2    Emberson, J.3    Baker, J.4    Tonkin, A.5    Hunt, D.6    MacMahon, S.7    Sharpe, N.8
  • 57
    • 0033084169 scopus 로고    scopus 로고
    • Effects of TGFB and bFGF on the differentiation of human bone marrow stromal fibroblasts
    • Locklin RM, Oreffo ROC, Triffit JT: Effects of TGFB and bFGF on the differentiation of human bone marrow stromal fibroblasts. Cell Biol Int 1999, 23:185-194.
    • (1999) Cell Biol. Int. , vol.23 , pp. 185-194
    • Locklin, R.M.1    Oreffo, R.O.C.2    Triffit, J.T.3
  • 59
    • 0029143553 scopus 로고
    • Effects of basic fibroblast growth factor (bFGF) on bone formation in growing rats
    • Nagai H, Tsukuda R, Mayahara H: Effects of basic fibroblast growth factor (bFGF) on bone formation in growing rats. Bone 1995, 16:367-373.
    • (1995) Bone , vol.16 , pp. 367-373
    • Nagai, H.1    Tsukuda, R.2    Mayahara, H.3
  • 60
    • 0033939597 scopus 로고    scopus 로고
    • Anabolic effects of basic fibroblast growth factor in the tibial diaphysis of ovariectomized rats
    • Pun S, Florio CL, Wronski TJ: Anabolic effects of basic fibroblast growth factor in the tibial diaphysis of ovariectomized rats. Bone 2000, 27:197-202.
    • (2000) Bone , vol.27 , pp. 197-202
    • Pun, S.1    Florio, C.L.2    Wronski, T.J.3
  • 61
    • 0034913870 scopus 로고    scopus 로고
    • Sequential treatment with basic fibroblast growth factor and parathyroid hormone restores lost cancellous bone mass and strength in the proximal tibia of aged ovariectomized rats
    • Wronski TJ, Ratkus AM, Thomsen JS, Vulcan O, Mosekilde L: Sequential treatment with basic fibroblast growth factor and parathyroid hormone restores lost cancellous bone mass and strength in the proximal tibia of aged ovariectomized rats. J Bone Miner Res 2001 16:1399-1407.
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 1399-1407
    • Wronski, T.J.1    Ratkus, A.M.2    Thomsen, J.S.3    Vulcan, O.4    Mosekilde, L.5
  • 62
    • 0041705932 scopus 로고    scopus 로고
    • Basic fibroblast growth factor forms new trabeculae that physically connect with pre-existing trabeculae, and this new bone is maintained with an anti-resorptive agent and enhanced with an anabolic agent in an osteopenic rat model
    • Lane NE, Kumer J, Yao W, Breunig T, Wronski T, Modin G, Kinney JH: Basic fibroblast growth factor forms new trabeculae that physically connect with pre-existing trabeculae, and this new bone is maintained with an anti-resorptive agent and enhanced with an anabolic agent in an osteopenic rat model. Osteoporos Int 2003, 14:374-352.
    • (2003) Osteoporos. Int. , vol.14 , pp. 352-374
    • Lane, N.E.1    Kumer, J.2    Yao, W.3    Breunig, T.4    Wronski, T.5    Modin, G.6    Kinney, J.H.7
  • 64
    • 0027185702 scopus 로고
    • Bone morphogenetic protein-2 causes commitment and differentiation in C3h10T1/2 and 3T3 cells
    • Wang EA, Israel DI, Kelly S, Luxenberg DP: Bone morphogenetic protein-2 causes commitment and differentiation in C3h10T1/2 and 3T3 cells. Growth Factors 1993 9:57-71.
    • (1993) Growth Factors , vol.9 , pp. 57-71
    • Wang, E.A.1    Israel, D.I.2    Kelly, S.3    Luxenberg, D.P.4
  • 65
    • 0027721063 scopus 로고
    • Expression of human bone morphogenetic proteins -2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages
    • Ahrens M, Ankenbauer T, Schroder D, Hollnagel A, Mayer H, Gross G: Expression of human bone morphogenetic proteins -2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages. DNA Cell Biol 1993 12:871-880.
    • (1993) DNA Cell Biol. , vol.12 , pp. 871-880
    • Ahrens, M.1    Ankenbauer, T.2    Schroder, D.3    Hollnagel, A.4    Mayer, H.5    Gross, G.6
  • 67
    • 0032100625 scopus 로고    scopus 로고
    • Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats
    • Onishi T, Ishidou Y, Nagamine T, Yone K, Imamura T, Kato M, Sampath TK, ten Dijke P, Sakou T: Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats. Bone 1998, 22:605-612.
    • (1998) Bone , vol.22 , pp. 605-612
    • Onishi, T.1    Ishidou, Y.2    Nagamine, T.3    Yone, K.4    Imamura, T.5    Kato, M.6    Sampath, T.K.7    ten Dijke, P.8    Sakou, T.9
  • 70
    • 0036899744 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures
    • Govender S, Csimma C, Genant HK, Valentin-Opran A: Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures. J Bone Joint Surg 2002, 84-A:2123-2134.
    • (2002) J. Bone Joint Surg. , vol.84 A , pp. 2123-2134
    • Govender, S.1    Csimma, C.2    Genant, H.K.3    Valentin-Opran, A.4
  • 71
    • 0036843201 scopus 로고    scopus 로고
    • Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2
    • Burkus JK, Transfeldt EE, Kitchel SH, Watkins RG, Balderstom RA: Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2. Spine 2002, 27:2396-2408.
    • (2002) Spine , vol.27 , pp. 2396-2408
    • Burkus, J.K.1    Transfeldt, E.E.2    Kitchel, S.H.3    Watkins, R.G.4    Balderstom, R.A.5
  • 72
    • 0141562066 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2-Genetics Institute/ Medtronic-Sofamor Danek/Integra, INFUSE Bone Graft, recombinant human bone morphogenetic protein 2-Genetics Institute/Mectronic-Sofamor Danek/Integra, RhBMP 2-Genetics Institute/Medtronic-Sofamor Danek/Integra
    • BMP 2-Genetics Institute/ Medtronic-Sofamor Danek/Integra
    • BMP 2-Genetics Institute/ Medtronic-Sofamor Danek/Integra. Bone morphogenetic protein 2-Genetics Institute/ Medtronic-Sofamor Danek/Integra, INFUSE Bone Graft, recombinant human bone morphogenetic protein 2-Genetics Institute/Mectronic-Sofamor Danek/Integra, RhBMP 2-Genetics Institute/Medtronic-Sofamor Danek/Integra. BioDrugs 2002, 16:376-377.
    • (2002) BioDrugs , vol.16 , pp. 376-377
  • 74
    • 0002071012 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: From basic science to clinical applications
    • Reddi AH: Bone morphogenetic proteins: from basic science to clinical applications. J Bone Joint Surg Am 2001, Suppl 1 (Pt 1):S1-6.
    • (2001) J. Bone Joint Surg. Am. , Issue.SUPPL. 1 PART 1
    • Reddi, A.H.1
  • 75
    • 0032728667 scopus 로고    scopus 로고
    • Osteogenic activity of OP-1 bone morphogenic protein (BMP-7) in a human fibular defect
    • Geesink RG, Hoefnagels NH, Bulstra SK: Osteogenic activity of OP-1 bone morphogenic protein (BMP-7) in a human fibular defect. J Bone Joint Surg Br 1999 81:710-718.
    • (1999) J. Bone Joint Surg. Br. , vol.81 , pp. 710-718
    • Geesink, R.G.1    Hoefnagels, N.H.2    Bulstra, S.K.3
  • 77
    • 0028043934 scopus 로고
    • In vivo evaluation of recombinant human osteogenic protein (rhOP-1) implants as a bone graft substitute for spinal fusions
    • Cook SD, Dalton JE, Tan EH, Whitecloud TS 3rd, Rueger DC; In vivo evaluation of recombinant human osteogenic protein (rhOP-1) implants as a bone graft substitute for spinal fusions. Spine 1994, 19:1655-1663.
    • (1994) Spine , vol.19 , pp. 1655-1663
    • Cook, S.D.1    Dalton, J.E.2    Tan, E.H.3    Whitecloud T.S. III4    Rueger, D.C.5
  • 78
    • 0032133452 scopus 로고    scopus 로고
    • Maxillary sinus augmentation in the non-human primate: A comparative radiographic and histologic study between recombinant human osteogenic protein-1 and natural bone mineral
    • Margolin MD, Cogan AG, Taylor M, Buck D, McAllister TN, Toth C, McAllister BS: Maxillary sinus augmentation in the non-human primate: a comparative radiographic and histologic study between recombinant human osteogenic protein-1 and natural bone mineral. J Periodontol 1998, 69:911-919.
    • (1998) J. Periodontol. , vol.69 , pp. 911-919
    • Margolin, M.D.1    Cogan, A.G.2    Taylor, M.3    Buck, D.4    McAllister, T.N.5    Toth, C.6    McAllister, B.S.7
  • 81
    • 0029090252 scopus 로고    scopus 로고
    • Treatment of postmenopausal osteoporosis with slow-release sodium fluoride: Final report of a randomized controlled trial
    • Pak CY, Sakhaee K, Adams-Huet B, Piziak V, Peterson RD, Poindexter JR:Treatment of postmenopausal osteoporosis with slow-release sodium fluoride: final report of a randomized controlled trial. Ann Intern Med 1999, 123:401-408.
    • (1999) Ann. Intern. Med. , vol.123 , pp. 401-408
    • Pak, C.Y.1    Sakhaee, K.2    Adams-Huet, B.3    Piziak, V.4    Peterson, R.D.5    Poindexter, J.R.6
  • 82
    • 0034762411 scopus 로고    scopus 로고
    • Treatment of osteoporosis in men with fluoride alone or in combination with bisphosphonates
    • Ringe JD, Rovati LC: Treatment of osteoporosis in men with fluoride alone or in combination with bisphosphonates. Calcif Tissue Int 2001, 69:252-255.
    • (2001) Calcif. Tissue Int. , vol.69 , pp. 252-255
    • Ringe, J.D.1    Rovati, L.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.