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Volumn 26, Issue 4, 2012, Pages 212-219

Vav1 GEF activity is required for T cell mediated allograft rejection

Author keywords

Allograft rejection; RhoGTPase; T cells; Vav

Indexed keywords

ALLOANTIBODY; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN VAV1; UNCLASSIFIED DRUG;

EID: 84860494600     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2012.03.003     Document Type: Article
Times cited : (6)

References (37)
  • 1
    • 77957734604 scopus 로고    scopus 로고
    • Rejection of the kidney allograft
    • Nankivell B.J., Alexander S.I. Rejection of the kidney allograft. N Engl J Med Oct 7 2010, 363(15):1451-1462.
    • (2010) N Engl J Med , vol.363 , Issue.15 , pp. 1451-1462
    • Nankivell, B.J.1    Alexander, S.I.2
  • 2
    • 10844292763 scopus 로고    scopus 로고
    • Immunosuppressive drugs for kidney transplantation
    • Halloran P.F. Immunosuppressive drugs for kidney transplantation. N Engl J Med Dec 23 2004, 351(26):2715-2729.
    • (2004) N Engl J Med , vol.351 , Issue.26 , pp. 2715-2729
    • Halloran, P.F.1
  • 3
    • 20944443148 scopus 로고    scopus 로고
    • Organ transplantation-how much of the promise has been realized?
    • Lechler R.I., Sykes M., Thomson A.W., Turka L.A. Organ transplantation-how much of the promise has been realized?. Nat Med Jun 2005, 11(6):605-613.
    • (2005) Nat Med , vol.11 , Issue.6 , pp. 605-613
    • Lechler, R.I.1    Sykes, M.2    Thomson, A.W.3    Turka, L.A.4
  • 5
    • 77951232521 scopus 로고    scopus 로고
    • Recent progress and new perspectives in studying T cell responses to allografts
    • Valujskikh A., Baldwin W.M., Fairchild R.L. Recent progress and new perspectives in studying T cell responses to allografts. Am J Transplant May 2010, 10(5):1117-1125.
    • (2010) Am J Transplant , vol.10 , Issue.5 , pp. 1117-1125
    • Valujskikh, A.1    Baldwin, W.M.2    Fairchild, R.L.3
  • 6
    • 0036631548 scopus 로고    scopus 로고
    • VAV proteins as signal integrators for multi-subunit immune-recognition receptors
    • Turner M., Billadeau D.D. VAV proteins as signal integrators for multi-subunit immune-recognition receptors. Nat Rev Immunol Jul 2002, 2(7):476-486.
    • (2002) Nat Rev Immunol , vol.2 , Issue.7 , pp. 476-486
    • Turner, M.1    Billadeau, D.D.2
  • 7
    • 18844449626 scopus 로고    scopus 로고
    • Vav-family proteins in T-cell signalling
    • Tybulewicz V.L. Vav-family proteins in T-cell signalling. Curr Opin Immunol Jun 2005, 17(3):267-274.
    • (2005) Curr Opin Immunol , vol.17 , Issue.3 , pp. 267-274
    • Tybulewicz, V.L.1
  • 8
    • 0030719389 scopus 로고    scopus 로고
    • A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes
    • Turner M., Mee P.J., Walters A.E., Quinn M.E., Mellor A.L., Zamoyska R., et al. A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes. Immunity Oct 1997, 7(4):451-460.
    • (1997) Immunity , vol.7 , Issue.4 , pp. 451-460
    • Turner, M.1    Mee, P.J.2    Walters, A.E.3    Quinn, M.E.4    Mellor, A.L.5    Zamoyska, R.6
  • 9
    • 0032981244 scopus 로고    scopus 로고
    • The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways
    • Costello P.S., Walters A.E., Mee P.J., Turner M., Reynolds L.F., Prisco A., et al. The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways. Proc Natl Acad Sci U S A Mar 16 1999, 96(6):3035-3040.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.6 , pp. 3035-3040
    • Costello, P.S.1    Walters, A.E.2    Mee, P.J.3    Turner, M.4    Reynolds, L.F.5    Prisco, A.6
  • 10
    • 2442444247 scopus 로고    scopus 로고
    • Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1
    • Reynolds L.F., de B.C., Norton T., Beeser A., Chernoff J., Tybulewicz V.L. Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1. J Biol Chem Apr 30 2004, 279(18):18239-18246.
    • (2004) J Biol Chem , vol.279 , Issue.18 , pp. 18239-18246
    • Reynolds, L.F.1    de, B.C.2    Norton, T.3    Beeser, A.4    Chernoff, J.5    Tybulewicz, V.L.6
  • 11
    • 0037029653 scopus 로고    scopus 로고
    • Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways
    • Reynolds L.F., Smyth L.A., Norton T., Freshney N., Downward J., Kioussis D., et al. Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways. J Exp Med May 6 2002, 195(9):1103-1114.
    • (2002) J Exp Med , vol.195 , Issue.9 , pp. 1103-1114
    • Reynolds, L.F.1    Smyth, L.A.2    Norton, T.3    Freshney, N.4    Downward, J.5    Kioussis, D.6
  • 12
    • 0037351084 scopus 로고    scopus 로고
    • Vav1 transduces TCR signals required for LFA-1 function and cell polarization at the immunological synapse
    • Ardouin L., Bracke M., Mathiot A., Pagakis S.N., Norton T., Hogg N., et al. Vav1 transduces TCR signals required for LFA-1 function and cell polarization at the immunological synapse. Eur J Immunol Mar 2003, 33(3):790-797.
    • (2003) Eur J Immunol , vol.33 , Issue.3 , pp. 790-797
    • Ardouin, L.1    Bracke, M.2    Mathiot, A.3    Pagakis, S.N.4    Norton, T.5    Hogg, N.6
  • 13
    • 0036199184 scopus 로고    scopus 로고
    • Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells
    • Krawczyk C., Oliveira-dos-Santos A., Sasaki T., Griffiths E., Ohashi P.S., Snapper S., et al. Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. Immunity Mar 2002, 16(3):331-343.
    • (2002) Immunity , vol.16 , Issue.3 , pp. 331-343
    • Krawczyk, C.1    Oliveira-dos-Santos, A.2    Sasaki, T.3    Griffiths, E.4    Ohashi, P.S.5    Snapper, S.6
  • 14
    • 45949104681 scopus 로고    scopus 로고
    • Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1
    • Chrencik J.E., Brooun A., Zhang H., Mathews I.I., Hura G.L., Foster S.A., et al. Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J Mol Biol Jul 25 2008, 380(5):828-843.
    • (2008) J Mol Biol , vol.380 , Issue.5 , pp. 828-843
    • Chrencik, J.E.1    Brooun, A.2    Zhang, H.3    Mathews, I.I.4    Hura, G.L.5    Foster, S.A.6
  • 15
    • 46449113353 scopus 로고    scopus 로고
    • Crucial structural role for the PH and C1 domains of the Vav1 exchange factor
    • Rapley J., Tybulewicz V.L., Rittinger K. Crucial structural role for the PH and C1 domains of the Vav1 exchange factor. EMBO Rep Jul 2008, 9(7):655-661.
    • (2008) EMBO Rep , vol.9 , Issue.7 , pp. 655-661
    • Rapley, J.1    Tybulewicz, V.L.2    Rittinger, K.3
  • 16
    • 44849141472 scopus 로고    scopus 로고
    • Internal dynamics control activation and activity of the autoinhibited Vav DH domain
    • Li P., Martins I.R., Amarasinghe G.K., Rosen M.K. Internal dynamics control activation and activity of the autoinhibited Vav DH domain. Nat Struct Mol Biol Jun 2008, 15(6):613-618.
    • (2008) Nat Struct Mol Biol , vol.15 , Issue.6 , pp. 613-618
    • Li, P.1    Martins, I.R.2    Amarasinghe, G.K.3    Rosen, M.K.4
  • 17
    • 0034269240 scopus 로고    scopus 로고
    • Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
    • Aghazadeh B., Lowry W.E., Huang X.Y., Rosen M.K. Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation. Cell Sep 1 2000, 102(5):625-633.
    • (2000) Cell , vol.102 , Issue.5 , pp. 625-633
    • Aghazadeh, B.1    Lowry, W.E.2    Huang, X.Y.3    Rosen, M.K.4
  • 18
    • 65449180370 scopus 로고    scopus 로고
    • Rac GTPases play critical roles in early T-cell development
    • Dumont C., Corsoni-Tadrzak A., Ruf S., de B.J., Williams A., Turner M., et al. Rac GTPases play critical roles in early T-cell development. Blood Apr 23 2009, 113(17):3990-3998.
    • (2009) Blood , vol.113 , Issue.17 , pp. 3990-3998
    • Dumont, C.1    Corsoni-Tadrzak, A.2    Ruf, S.3    de, B.J.4    Williams, A.5    Turner, M.6
  • 19
    • 0034305495 scopus 로고    scopus 로고
    • Control of pre-T cell proliferation and differentiation by the GTPase Rac-I
    • Gomez M., Tybulewicz V., Cantrell D.A. Control of pre-T cell proliferation and differentiation by the GTPase Rac-I. Nat Immunol Oct 2000, 1(4):348-352.
    • (2000) Nat Immunol , vol.1 , Issue.4 , pp. 348-352
    • Gomez, M.1    Tybulewicz, V.2    Cantrell, D.A.3
  • 20
    • 77649214306 scopus 로고    scopus 로고
    • Function of the nucleotide exchange activity of vav1 in T cell development and activation
    • Saveliev A., Vanes L., Ksionda O., Rapley J., Smerdon S.J., Rittinger K., et al. Function of the nucleotide exchange activity of vav1 in T cell development and activation. Sci Signal 2009, 2(101):ra83.
    • (2009) Sci Signal , vol.2 , Issue.101
    • Saveliev, A.1    Vanes, L.2    Ksionda, O.3    Rapley, J.4    Smerdon, S.J.5    Rittinger, K.6
  • 21
    • 22144473737 scopus 로고    scopus 로고
    • Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects
    • Paccani S.R., Boncristiano M., Patrussi L., Ulivieri C., Wack A., Valensin S., et al. Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects. Blood Jul 15 2005, 106(2):626-634.
    • (2005) Blood , vol.106 , Issue.2 , pp. 626-634
    • Paccani, S.R.1    Boncristiano, M.2    Patrussi, L.3    Ulivieri, C.4    Wack, A.5    Valensin, S.6
  • 22
    • 0038546809 scopus 로고    scopus 로고
    • Vav1-deficient mice are resistant to MOG-induced experimental autoimmune encephalomyelitis due to impaired antigen priming
    • Korn T., Fischer K.D., Girkontaite I., Kollner G., Toyka K., Jung S. Vav1-deficient mice are resistant to MOG-induced experimental autoimmune encephalomyelitis due to impaired antigen priming. J Neuroimmunol Jun 2003, 139(1-2):17-26.
    • (2003) J Neuroimmunol , vol.139 , Issue.1-2 , pp. 17-26
    • Korn, T.1    Fischer, K.D.2    Girkontaite, I.3    Kollner, G.4    Toyka, K.5    Jung, S.6
  • 23
    • 33847212511 scopus 로고    scopus 로고
    • Strongly reduced alloreactivity and long-term survival times of cardiac allografts in Vav1- and Vav1/Vav2-knockout mice
    • Weckbecker G., Bruns C., Fischer K.D., Heusser C., Li J., Metzler B., et al. Strongly reduced alloreactivity and long-term survival times of cardiac allografts in Vav1- and Vav1/Vav2-knockout mice. Transpl Int Apr 2007, 20(4):353-364.
    • (2007) Transpl Int , vol.20 , Issue.4 , pp. 353-364
    • Weckbecker, G.1    Bruns, C.2    Fischer, K.D.3    Heusser, C.4    Li, J.5    Metzler, B.6
  • 24
    • 0015866545 scopus 로고
    • Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection
    • Corry R.J., Winn H.J., Russell P.S. Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection. Transplantation Oct 1973, 16(4):343-350.
    • (1973) Transplantation , vol.16 , Issue.4 , pp. 343-350
    • Corry, R.J.1    Winn, H.J.2    Russell, P.S.3
  • 25
    • 22144434185 scopus 로고    scopus 로고
    • Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection
    • Stewart S., Winters G.L., Fishbein M.C., Tazelaar H.D., Kobashigawa J., Abrams J., et al. Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection. J Heart Lung Transplant Nov 2005, 24(11):1710-1720.
    • (2005) J Heart Lung Transplant , vol.24 , Issue.11 , pp. 1710-1720
    • Stewart, S.1    Winters, G.L.2    Fishbein, M.C.3    Tazelaar, H.D.4    Kobashigawa, J.5    Abrams, J.6
  • 26
    • 10744222965 scopus 로고    scopus 로고
    • Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells
    • Fujikawa K., Miletic A.V., Alt F.W., Faccio R., Brown T., Hoog J., et al. Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells. J Exp Med Nov 17 2003, 198(10):1595-1608.
    • (2003) J Exp Med , vol.198 , Issue.10 , pp. 1595-1608
    • Fujikawa, K.1    Miletic, A.V.2    Alt, F.W.3    Faccio, R.4    Brown, T.5    Hoog, J.6
  • 27
    • 33749516648 scopus 로고    scopus 로고
    • Vav1 promotes T cell cycle progression by linking TCR/CD28 costimulation to FOXO1 and p27kip1 expression
    • Charvet C., Canonigo A.J., Becart S., Maurer U., Miletic A.V., Swat W., et al. Vav1 promotes T cell cycle progression by linking TCR/CD28 costimulation to FOXO1 and p27kip1 expression. J Immunol Oct 15 2006, 177(8):5024-5031.
    • (2006) J Immunol , vol.177 , Issue.8 , pp. 5024-5031
    • Charvet, C.1    Canonigo, A.J.2    Becart, S.3    Maurer, U.4    Miletic, A.V.5    Swat, W.6
  • 28
    • 20044389090 scopus 로고    scopus 로고
    • Immunomodulatory benefits of cyclosporine A in inflammatory bowel disease
    • Kountouras J., Zavos C., Chatzopoulos D. Immunomodulatory benefits of cyclosporine A in inflammatory bowel disease. J Cell Mol Med Jul 2004, 8(3):317-328.
    • (2004) J Cell Mol Med , vol.8 , Issue.3 , pp. 317-328
    • Kountouras, J.1    Zavos, C.2    Chatzopoulos, D.3
  • 29
    • 34250316874 scopus 로고    scopus 로고
    • Enhanced cardiac allograft survival by Vav1-Rac signaling blockade in a mouse model
    • Wang S., Diao H., Guan Q., Jevnikar A.M., Du C. Enhanced cardiac allograft survival by Vav1-Rac signaling blockade in a mouse model. Transpl Immunol Jul 2007, 18(1):53-61.
    • (2007) Transpl Immunol , vol.18 , Issue.1 , pp. 53-61
    • Wang, S.1    Diao, H.2    Guan, Q.3    Jevnikar, A.M.4    Du, C.5
  • 30
  • 31
    • 0033168892 scopus 로고    scopus 로고
    • The guanine-nucleotide exchange factor Vav is a crucial regulator of B cell receptor activation and B cell responses to nonrepetitive antigens
    • Bachmann M.F., Nitschke L., Krawczyk C., Tedford K., Ohashi P.S., Fischer K.D., et al. The guanine-nucleotide exchange factor Vav is a crucial regulator of B cell receptor activation and B cell responses to nonrepetitive antigens. J Immunol Jul 1 1999, 163(1):137-142.
    • (1999) J Immunol , vol.163 , Issue.1 , pp. 137-142
    • Bachmann, M.F.1    Nitschke, L.2    Krawczyk, C.3    Tedford, K.4    Ohashi, P.S.5    Fischer, K.D.6
  • 33
    • 65549091120 scopus 로고    scopus 로고
    • T-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue
    • David R., Ma L., Ivetic A., Takesono A., Ridley A.J., Chai J.G., et al. T-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue. Blood Apr 16 2009, 113(16):3696-3705.
    • (2009) Blood , vol.113 , Issue.16 , pp. 3696-3705
    • David, R.1    Ma, L.2    Ivetic, A.3    Takesono, A.4    Ridley, A.J.5    Chai, J.G.6
  • 34
    • 0034292369 scopus 로고    scopus 로고
    • CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation
    • Michel F., Mangino G., Attal-Bonnefoy G., Tuosto L., Alcover A., Roumier A., et al. CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation. J Immunol Oct 1 2000, 165(7):3820-3829.
    • (2000) J Immunol , vol.165 , Issue.7 , pp. 3820-3829
    • Michel, F.1    Mangino, G.2    Attal-Bonnefoy, G.3    Tuosto, L.4    Alcover, A.5    Roumier, A.6
  • 35
    • 33846526236 scopus 로고    scopus 로고
    • Mitogenic CD28 signals require the exchange factor Vav1 to enhance TCR signaling at the SLP-76-Vav-Itk signalosome
    • Dennehy K.M., Elias F., Na S.Y., Fischer K.D., Hunig T., Luhder F. Mitogenic CD28 signals require the exchange factor Vav1 to enhance TCR signaling at the SLP-76-Vav-Itk signalosome. J Immunol Feb 1 2007, 178(3):1363-1371.
    • (2007) J Immunol , vol.178 , Issue.3 , pp. 1363-1371
    • Dennehy, K.M.1    Elias, F.2    Na, S.Y.3    Fischer, K.D.4    Hunig, T.5    Luhder, F.6
  • 36
    • 0142259712 scopus 로고    scopus 로고
    • Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
    • Rudd C.E., Schneider H. Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling. Nat Rev Immunol Jul 2003, 3(7):544-556.
    • (2003) Nat Rev Immunol , vol.3 , Issue.7 , pp. 544-556
    • Rudd, C.E.1    Schneider, H.2
  • 37
    • 0036180783 scopus 로고    scopus 로고
    • Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1
    • Marinari B., Costanzo A., Viola A., Michel F., Mangino G., Acuto O., et al. Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1. Eur J Immunol Feb 2002, 32(2):447-456.
    • (2002) Eur J Immunol , vol.32 , Issue.2 , pp. 447-456
    • Marinari, B.1    Costanzo, A.2    Viola, A.3    Michel, F.4    Mangino, G.5    Acuto, O.6


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