메뉴 건너뛰기




Volumn 29, Issue 2, 1999, Pages 477-487

Defective immunoglobulin class switching in Vav-deficient mice is attributable to compromised T cell help

Author keywords

Isotype switching; Knockout; Lymphocyte; T cell B cell collaboration; Transgenic

Indexed keywords

B LYMPHOCYTE ANTIGEN; CELL RECEPTOR; FICOLL; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; HAPTEN; HELPER FACTOR; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN G; INTERLEUKIN 4; MESSENGER RNA; RHO FACTOR; T LYMPHOCYTE RECEPTOR;

EID: 0033065116     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199902)29:02<477::AID-IMMU477>3.0.CO;2-V     Document Type: Article
Times cited : (44)

References (41)
  • 1
    • 0024433697 scopus 로고
    • Vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells
    • Katzav, S., Martin-Zanca, D. and Barbacid, M., Vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells. EMBO J. 1989. 8: 2283-2290.
    • (1989) EMBO J. , vol.8 , pp. 2283-2290
    • Katzav, S.1    Martin-Zanca, D.2    Barbacid, M.3
  • 2
    • 0026591451 scopus 로고
    • The hematopoietically expressed vav protooncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization
    • Adams, J. M., Houston, H., Allen, J., Lints, T. and Harvey, R., The hematopoietically expressed vav protooncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization. Oncogene 1992. 7: 611-618.
    • (1992) Oncogene , vol.7 , pp. 611-618
    • Adams, J.M.1    Houston, H.2    Allen, J.3    Lints, T.4    Harvey, R.5
  • 4
    • 0031033292 scopus 로고    scopus 로고
    • Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the Vav protooncogene product
    • Crespo, P., Schuebel, K. E., Ostrom, A. A., Gutkind, J. S. and Bustelo, X. R., Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the Vav protooncogene product. Nature 1997. 385: 169-172.
    • (1997) Nature , vol.385 , pp. 169-172
    • Crespo, P.1    Schuebel, K.E.2    Ostrom, A.A.3    Gutkind, J.S.4    Bustelo, X.R.5
  • 6
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signalling networks
    • Van Aelst, L. and D'Souza-Schorey, C., Rho GTPases and signalling networks. Genes Dev. 1997. 11: 2295-2322.
    • (1997) Genes Dev. , vol.11 , pp. 2295-2322
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 7
    • 0030719389 scopus 로고    scopus 로고
    • A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes
    • Turner, M., Mee, P. J., Walters, A. E., Quinn, M. E., Mellor, A. L, Zamoyska, R. and Tybulewicz, V. L. J., A requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes. Immunity 1997. 7: 451-460.
    • (1997) Immunity , vol.7 , pp. 451-460
    • Turner, M.1    Mee, P.J.2    Walters, A.E.3    Quinn, M.E.4    Mellor, A.L.5    Zamoyska, R.6    Tybulewicz, V.L.J.7
  • 9
    • 0032493028 scopus 로고    scopus 로고
    • Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
    • Holsinger, L. J., Graef, I. A., Swat, W., Chi, T., Bautista, D. M., Davidson, L., Lewis, R. S., Alt, F. W. and Crabtree, G. R., Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction. Curr. Biol. 1998. 8: 563-572.
    • (1998) Curr. Biol. , vol.8 , pp. 563-572
    • Holsinger, L.J.1    Graef, I.A.2    Swat, W.3    Chi, T.4    Bautista, D.M.5    Davidson, L.6    Lewis, R.S.7    Alt, F.W.8    Crabtree, G.R.9
  • 10
    • 0032076954 scopus 로고    scopus 로고
    • CD19 as a membrane-anchored adaptor protein of B lymphocytes: Costimulation of lipid and protein kinases by recruitment of Vav
    • O'Rourke, L, Tooze, R., Turner, M., Sandoval, D. M., Carter, R. H., Tybulewicz, V. L. J. and Fearon, D. T., CD19 as a membrane-Anchored Adaptor protein of B Lymphocytes: Costimulation of Lipid and protein Kinases by Recruitment of Vav. Immunity 1998. 8: 635-645.
    • (1998) Immunity , vol.8 , pp. 635-645
    • O'Rourke, L.1    Tooze, R.2    Turner, M.3    Sandoval, D.M.4    Carter, R.H.5    Tybulewicz, V.L.J.6    Fearon, D.T.7
  • 11
    • 0001584956 scopus 로고    scopus 로고
    • Vav and SLP-76 infract and functionally cooperate in IL-2 gene activation
    • Wu, J., Motto, D. G., Koretzky, G. A. and Weiss, A., Vav and SLP-76 infract and functionally cooperate in IL-2 gene activation. Immunity 1996. 4: 593-602.
    • (1996) Immunity , vol.4 , pp. 593-602
    • Wu, J.1    Motto, D.G.2    Koretzky, G.A.3    Weiss, A.4
  • 14
    • 0028956337 scopus 로고
    • Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav
    • Tarakhovsky, A., Turner, M., Schaal, S., Mee, P. J., Duddy, L. P., Rajewsky, K. and Tybulewicz, V. L., Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. Nature 1995. 374: 467-470.
    • (1995) Nature , vol.374 , pp. 467-470
    • Tarakhovsky, A.1    Turner, M.2    Schaal, S.3    Mee, P.J.4    Duddy, L.P.5    Rajewsky, K.6    Tybulewicz, V.L.7
  • 15
    • 0028915948 scopus 로고
    • Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the Vav proto-oncogene
    • Zhang, R., Alt, F. W., Davidson, L., Orkin, S. H. and Swat, W., Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the Vav proto-oncogene. Nature 1995. 374: 470-473.
    • (1995) Nature , vol.374 , pp. 470-473
    • Zhang, R.1    Alt, F.W.2    Davidson, L.3    Orkin, S.H.4    Swat, W.5
  • 17
    • 0029813549 scopus 로고    scopus 로고
    • Sequential antigen-specific growth of T cells in the T zones and follicles in response to pigeon cytochrome c
    • Gulbranson-Judge, A. and MacLennan, I., Sequential antigen-specific growth of T cells in the T zones and follicles in response to pigeon cytochrome c. Eur. J. Immunol. 1996. 26: 1830-1837.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1830-1837
    • Gulbranson-Judge, A.1    MacLennan, I.2
  • 18
  • 19
    • 0029971182 scopus 로고    scopus 로고
    • Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation
    • Toellner, K.-M., Gulbranson-Judge, A., Taylor, D. R., Sze, D. M. Y. and MacLennan, I. C. M., Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation. J. Exp. Med. 1996. 183: 2303-2312.
    • (1996) J. Exp. Med. , vol.183 , pp. 2303-2312
    • Toellner, K.-M.1    Gulbranson-Judge, A.2    Taylor, D.R.3    Sze, D.M.Y.4    MacLennan, I.C.M.5
  • 20
    • 0032550353 scopus 로고    scopus 로고
    • T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching
    • Toellner, K.-M., Luther, S. A., Sze, D. M.-Y., Choy, R. K.-W., Taylor, D. R., MacLennan, I. C. M. and Acha Orbea, H., T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching. J. Exp. Med. 1998. 187: 1193-1204.
    • (1998) J. Exp. Med. , vol.187 , pp. 1193-1204
    • Toellner, K.-M.1    Luther, S.A.2    Sze, D.M.-Y.3    Choy, R.K.-W.4    Taylor, D.R.5    MacLennan, I.C.M.6    Acha Orbea, H.7
  • 21
    • 0029094609 scopus 로고
    • Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
    • Engel, P., Zhou, L-J., Ord, D. C., Sato, S., Koller, B. and Tedder, T. R, Abnormal B Lymphocyte Development, Activation, and Differentiation in Mice that lack or Overexpress the CD19 Signal Transduction Molecule. Immunity 1995. 3: 39-50.
    • (1995) Immunity , vol.3 , pp. 39-50
    • Engel, P.1    Zhou, L.-J.2    Ord, D.C.3    Sato, S.4    Koller, B.5    Tedder, T.R.6
  • 22
    • 0029064680 scopus 로고
    • Impairment of T-cell-dependent B-cell responses and B1 cell development in CD19-deficient mice
    • Rickert, R. C., Rajewsky, K. and Roes, J., Impairment of T-cell-dependent B-cell responses and B1 cell development in CD19-deficient mice. Nature 1995. 376: 352-355.
    • (1995) Nature , vol.376 , pp. 352-355
    • Rickert, R.C.1    Rajewsky, K.2    Roes, J.3
  • 23
    • 0030911856 scopus 로고    scopus 로고
    • Bar Mitzvah for B-1 cells: How will they grow up?
    • Tarakhovsky, A., Bar Mitzvah for B-1 cells: how will they grow up? J. Exp. Med. 1997. 185: 981-984.
    • (1997) J. Exp. Med. , vol.185 , pp. 981-984
    • Tarakhovsky, A.1
  • 24
    • 0028597993 scopus 로고
    • Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/ phosphatidylinositol 3-kinase complex in human B cell precursors
    • Weng, W. K., Jarvis, L. and LeBien, T. W., Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/ phosphatidylinositol 3-kinase complex in human B cell precursors. J. Biol. Chem. 1994. 269: 32514-32521.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32514-32521
    • Weng, W.K.1    Jarvis, L.2    LeBien, T.W.3
  • 26
    • 0029558617 scopus 로고
    • The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation
    • Sato, S., Steeber, D. A. and Tedder, T. F., The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation. Proc. Natl. Acad. Sci. USA 1995. 92: 11558-11562.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11558-11562
    • Sato, S.1    Steeber, D.A.2    Tedder, T.F.3
  • 28
    • 0028447437 scopus 로고
    • The immune-responses in CD40-deficient mice-impaired immunoglobulin class switching and germinal center formation
    • Kawabe, T., Naka, T, Yoshida, K., Tanaka, T, Fujiwara, H. and Suematsu, S., The immune-responses in CD40-deficient mice-impaired immunoglobulin class switching and germinal center formation. Immunity 1994. 1:167-178.
    • (1994) Immunity , vol.1 , pp. 167-178
    • Kawabe, T.1    Naka, T.2    Yoshida, K.3    Tanaka, T.4    Fujiwara, H.5    Suematsu, S.6
  • 30
    • 0028055141 scopus 로고
    • Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4(+) T cells and defective antibody production in vivo
    • Ronchese, R, Haussman, B., Hubele, S. and Lane, P. J. L., Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4(+) T cells and defective antibody production in vivo. J. Exp. Med. 1994. 179.
    • (1994) J. Exp. Med. , pp. 179
    • Ronchese, R.1    Haussman, B.2    Hubele, S.3    Lane, P.J.L.4
  • 33
    • 0029989758 scopus 로고    scopus 로고
    • CD28 is required for germinal center formation
    • Ferguson, S., Han, S., Kelsoe, G. and Thompson, C., CD28 is required for germinal center formation. J. Immunol. 1996. 156: 4576-4581.
    • (1996) J. Immunol. , vol.156 , pp. 4576-4581
    • Ferguson, S.1    Han, S.2    Kelsoe, G.3    Thompson, C.4
  • 34
  • 35
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kuhn, R., Rajewsky, K. and Muller, W., Generation and analysis of interleukin-4 deficient mice. Science 1991. 254: 707-710.
    • (1991) Science , vol.254 , pp. 707-710
    • Kuhn, R.1    Rajewsky, K.2    Muller, W.3
  • 36
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NF-AT family: Regulation and function
    • Rao, A., Luo, C. and Hogan, P. C., Transcription factors of the NF-AT family: regulation and function. Annu. Rev. Immunol. 1997. 15: 707-747.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.C.3
  • 41
    • 0001364530 scopus 로고
    • Principles and methods for the morphometric study of the lung and other organs
    • Weibel, E. R., Principles and Methods for the morphometric study of the lung and other organs. Lab. Invest. 1963. 12: 131-155.
    • (1963) Lab. Invest. , vol.12 , pp. 131-155
    • Weibel, E.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.