In vitro inhibition of key enzymes related to diabetes by the aqueous extracts of some fruits of West Bengal, India

Current Nutrition and Food Science

Volumn 8, Issue 1, 2012, Pages 19-24

  Das, Susmita ^a   Das, Sukriti ^a   De, Bratati ^a  

^a UNIVERSITY OF CALCUTTA   (India)

Author keywords

Achras sapota; Antidiabetic; Flavonoids; Fruits; Phenols; Phoenix sylvestris; amylase; glucosidase

Indexed keywords

ACHRAS SAPOTA EXTRACT; ALPHA GLUCOSIDASE; AMYLASE; CARBOHYDRATE; FLAVONOID; PHOENIX SYLVESTRIS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DATE (FRUIT); DIABETES MELLITUS; ENZYME INHIBITION; IC 50; IN VITRO STUDY; INDIA; NONHUMAN; PHYLOGENETIC TREE; PHYSALIS; PRIORITY JOURNAL; SAPODILLA; SEASON;

BORASSUS FLABELLIFER; MANILKARA ZAPOTA; PHOENIX SYLVESTRIS; PHYSALIS PERUVIANA;

EID: 84860493330     PISSN: 15734013     EISSN: 22123881     Source Type: Journal    
DOI: 10.2174/157340112800269614     Document Type: Article

References (34)

1. Dehghan-Kooshkghazi M, Mathers JC. Starch digestion, largebowel fermentation and intestinal mucosal cell proliferation in rats treated with the alpha-glucosidase inhibitor acarbose. Br J Nutr 2004; 91: 357-65.
2. Jenkins DJA, Kendall CWC, Augustin LSA, et al. Glycemic index: Overview of implications in health and disease. Am J Clin Nutr 2002; 76: 266-73.
3. Layer P, Zinsmeister AR, DiMagno EP. Effects of decreasing intraluminal amylase activity on starch digestion and postprandial gastrointestinal function in humans. Gastroenterology 1986; 91: 41-8.
4. Casirola DM, Ferraris RP. α -glucosidase inhibitors prevent dietinduced increases in intestinal sugar transport in diabetic mice. Metabolism 2006; 55: 832-41.
5. Puls W, Keup U, Krause HP, Thomas G, Hoffmeister F. Glucosidase inhibition, A new approach to the treatment of diabetes, obesity, and hyperlipoproteinaemia. Naturwissenschaften 1977; 64: 536-7.
6. Cannell RJP, Farmer P, Walker JM. Purification and characterization of pentagalloylglucose, and α -glucosidase inhibitor/antibiotic from the freshwater green alga Spirogyra varians. Biochem J 1988; 255: 937-41.
7. Murai A, Iwamura K, Takada M, Ogawa K, Usui T, Okumura Ji. Control of postprandial hyperglycaemia by galactosyl maltobionolactone and its novel anti-amylase effect in mice. Life Sciences 2002; 71: 1405-15.
8. McCue P, Kwon Y, Shetty K. Antidiabetic and antihypertensive potential of sprouted and solid-state bioprocessed soybean. Asia Pac J Clin Nutr 2005; 14: 145-52.
9. Asano N. Glycosidase inhibitors: update and perspectives on practical use. Glycobiology 2003; 13: 93R-104R.
10. Hansawasdi C, Kawabata J, Kasai T. α -Amylase inhibitors from roselle (Hibiscus sabdariffa Linn.) tea. Biosci Biotechnol Biochem 2000; 64: 1041-3.
11. Matsui T, Ueda T, Oki T, Sugita K, Terahara N, Natsumoto. K- αGlucosidase inhibitory action of natural acylated anthocyanins. J Agr Food Chem 2001; 50: 1952-6.
12. Matsui T, Yoshimoto C, Osajima K, Oki T, Osajima Y. In vitro survey of α-glucosidase inhibitory food components. Biosci Biotechnol Biochem 1996; 60: 2019-22.
13. Nishioka T, Watanabe J, Kawabata J, Niki R. Isolation and activity of N p-coumaroyltyramine, an α -glucosidase inhibitor in welsh onion (Allium fistulosum). Biosci Biotechnol Biochem 1997; 61: 1138-41.
14. Watanabe J, Kawabata J, Kurihara H, Niki R. Isolation and identification of α-glucosidase inhibitors from Tochu-cha (Eucommia ulmoides). Biosci Biotechnol Biochem 1997; 61: 177-8.
15. Jenkins DJA, Taylor RH, Goff DV, et al. Scope and specificity of acarbose in slowing carbohydrate absorption in man. Diabetes 1981; 30: 951-4.
16. Kwon YI, Apostolidis E, Shetty K. In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension. Bioresource Technology 2008; 99: 2981-8.
17. Bernfeld P. Amylase, α and β. Meth Enzymol 1955; 1: 149-58.
18. Sadasivam S, Manikam A. Biochemical Methods. Wiley Eastern Limited, India 1992; pp.187-8.
19. Kim D, Jeong SW, Lee CY. Antioxidant capacity of phenolic phytochemicals from various cultivars of plums. Food Chem 2003; 81: 321-6.
20. Evenepoel P, Bammens B, Verbeke K, Vanrenterghem Y. Acarbose treatment lowers generation and serum concentrations of the protein-bound solute p-cresol: A pilot study. Kidney Int 2006; 70: 192-8.
21. Gonc-alves A, Franco ML, Genovesse MI. Chemical composition and antioxidant/antidiabetic potential of brazilian native fruits and commercial frozen pulps. J Agr Food Chem 2010; 58: 4666-74.
22. Pinto Mda S, Ranilla LG, Apostolidis E, Lajolo FM, Genovese MI, Shetty K. Evaluation of antihyperglycemia and antihypertension potential of native Peruvian fruits using in vitro models. J Med Food 2009; 12: 278-91
23. Barbosa AC, Pinto Mda S, Sarkar D, Ankolekar C, Greene D, Shetty K. Varietal influences on antihyperglycemia properties of freshly harvested apples using in vitro assay models. J Med Food 2010; 13: 1313-23.
24. Pinto Mda S, de Carvalho JE, Lajolo FM, Genovese MI, Shetty K. Evaluation of antiproliferative, anti-type 2 diabetes, and antihypertension potentials of ellagitannins from strawberries (Fragaria ×ananassa Duch.) using in vitro models. J Med Food 2010; 13: 1027-35.
25. Pinto Mda S, Ghaedian R, Shinde R, Shetty K. Potential of cranberry powder for management of hyperglycemia using in vitro models. J Med Food 2010; 13: 1036-44.
26. Itankar PR, Lokhande SJ, Verma PR, Arora SK, Sahu RA, Patil AT. Antidiabetic potential of unripe Carissa carandas Linn. fruit extract. J Ethnopharmacol 2011; 135: 430-3.
27. Nagappa AN, Thakurdesai PA, Venkat Rao N, Singh J. Antidiabetic activity of Terminalia catappa Linn fruits. J Ethnopharmacol 2003; 88: 45-50.
28. Dewanjee S, Das AK, Sahu R, Gangopadhyay M. Antidiabetic activity of Diospyros peregrina fruit: effect on hyperglycemia, hyperlipidemia and augmented oxidative stress in experimental type 2 diabetes. Food Chem Toxicol 2009; 47: 2679-85.
29. Rai PK, Mehta S, Watal G. Hypolipidaemic & hepatoprotective effects of Psidium guajava raw fruit peel in experimental diabetes. Indian J Med Res 2010; 131: 820-4.
30. Kamalakkannan N, Prince PS. The effect of Aegle marmelos fruit extract in streptozotocin diabetes: a histopathological study. J Herbal Pharmacother 2005; 5: 87-96.
31. Gupta RK, Kesari AN, Watal G, Murthy PS, Chandra R, Tandon V. Nutritional and hypoglycemic effect of fruit pulp of Annona squamosa in normal healthy and alloxan-induced diabetic rabbits. Ann Nutr Metab 2005; 49:407-13.
32. Jarald EE, Joshi SB, Jain DC. Antidiabetic activity of extracts and fraction of Zizyphus mauritiana. Pharm Biol 2009; 47: 328-34.
33. Chi-Fai Chau, Chien-Hung Chen, Ching-Yi Lin. Insoluble fiberrich fractions derived from Averrhoa carambola:hypoglycemic effects determined by in vitro methods. Lebensm. Wiss. u.-Technol 2004; 37: 331-5.
34. McDougall GJ, Shpiro F, Dobson P, Smith P, Blake A, Stewart D. Different polyphenolic components of soft fruits inhibit alphaamylase and alpha-glucosidase. J Agr Food Chem 2005; 53: 2760-6.