Pseudolaric acid B induces mitotic catastrophe followed by apoptotic cell death in murine fibrosarcoma L929 cells

European Journal of Pharmacology

Volumn 683, Issue 1-3, 2012, Pages 16-26

  Qi, Min ^a   Yao, Guodong ^a   Fan, Simiao ^a   Cheng, Weiwei ^a   Tashiro, Shin Ichi ^b   Onodera, Satoshi ^b   Ikejima, Takashi ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Mitotic catastrophe; Mitotic phase arrest; Mitotic slippage; Multinucleated cell; Pseudolaric acid B

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 1; PSEUDOLARIC ACID B;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL STRAIN L 929; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; MITOSIS INDEX; MITOSIS SPINDLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; ANIMALS, NEWBORN; ANTIMITOTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CDC2 PROTEIN KINASE; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; CYCLIN B1; CYTOSOL; DITERPENES; DOWN-REGULATION; FIBROBLASTS; FIBROSARCOMA; GIANT CELLS; HUMANS; MICE; MITOSIS; NEOPLASM PROTEINS;

EID: 84860486010     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.02.035     Document Type: Article

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