Pharicin A, a novel natural ent-kaurene diterpenoid, induces mitotic arrest and mitotic catastrophe of cancer cells by interfering with BubR1 function

Cell Cycle

Volumn 9, Issue 14, 2010, Pages 2969-2979

  Xu, Han Zhang ^a   Huang, Ying ^a,b   Wu, Ying Li ^a   Zhao, Yong ^c   Xiao, Wei Lie ^c   Lin, Qi Shan ^d   Sun, Han Dong ^c   Dai, Wei ^b   Chen, Guo Qiang ^a,e  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KUNMING INSTITUTE OF BOTANY   (China)

^d STATE UNIVERSITY OF NEW YORK   (United States)

^e Chinese Academy of Sciences   (China)

Author keywords

Leukemia; Mitotic arrest; Pharicin A; Spindle checkpoint; Tumor cells

Indexed keywords

BUB1 RELATED PROTEIN; DITERPENOID; PACLITAXEL; PHARICIN A; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CANCER CELL; CELL STRUCTURE; CHROMOSOME; CONTROLLED STUDY; DNA CONTENT; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; ISODON; LEUKEMIA; MITOSIS INHIBITION; PROTEIN BINDING; PROTEIN LOCALIZATION; SISTER CHROMATID; SOLID TUMOR; SPINDLE CELL; WESTERN BLOTTING;

ISODON;

EID: 77956795019     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.14.12406     Document Type: Article

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