Splitting the chromosome: Cutting the ties that bind sister chromatids

Novartis Foundation Symposium

Volumn 237, Issue , 2001, Pages 113-138

  Nasmyth, Kim ^a   Peters, Jan Michael ^a   Uhlmann, Frank ^a  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; COHESINS; FUNGAL PROTEIN; NONHISTONE PROTEIN; NUCLEAR PROTEIN;

ANIMAL; CHROMATID; DNA REPLICATION; METABOLISM; MITOSIS; MITOSIS SPINDLE; PHYSIOLOGY; PROTEIN CONFORMATION; REVIEW; ULTRASTRUCTURE;

ANIMALS; CELL CYCLE PROTEINS; CHROMATIDS; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA REPLICATION; FUNGAL PROTEINS; MITOSIS; MITOTIC SPINDLE APPARATUS; NUCLEAR PROTEINS; PROTEIN CONFORMATION;

EID: 0035230592     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (93)

1. Akhmedov AT, Gross B, Jessberger R 1999 Mammalian SMC3 C-terminal and coiled-coil protein domains specifically bind palindromic DNA, do not block DNA ends, and prevent DNA bending. J Biol Chem 274:38216-38224
2. Alexandru G, Zachariae W, Schleiffer A, Nasmyth K 1999 Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage. EMBO J 18:2707-2721
3. Amon A 1999 The spindle checkpoint. Curr Opin Genet Dev 9:69-75
4. Barrett AJ, Rawlings ND, Woessner JF (eds) 1998 Handbook of proteolytic enzymes. Academic Press, London
5. Basu J, Bousbaa H, Logarinho E et al 1999 Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila. J Cell Biol 146:13-28
6. Belar K 1929 Beiträge zur Kausalanyse der Mitose. Wilhelm Roux' Arch Entwicklungsmech Org 118:359-484
7. Blat Y, Kleckner N 1999 Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. Cell 98:249-259
8. Cahill DP, Lengauer C, Yu J et al 1998 Mutations of mitotic checkpoint genes in human cancers. Nature 392:300-303
9. Chen JM, Rawlings ND, Stevens RA, Barrett AJ 1998 Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases. FEBS Lett 441:361-365
10. Ciosk R, Zachariae W, Michaelis C, Shevchenko A, Mann M, Nasmyth K 1998 An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93:1067-1076
11. Ciosk R, Shirayama M, Shevchenko A, Tanaka T, Toth A, Shevchenko A, Nasmyth K 2000 Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol Cell 5:243-254
12. Cohen-Fix O, Peters JM, Kirschner MW, Koshland D 1996 Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev 10:3081-3093
13. Comings DE 1966 Centromere: absence of DNA replication during chromatid separation in human fibroblasts. Science 154:1463-1464
14. Darlington CD 1939 The evolution of genetic systems. Basic Books, New York
15. Davis BK 1971 Genetic analysis of a meiotic mutant resulting in precocious sister-centromere separation in Drosophila melanogaster. Mol Gen Genet 113:251-272
16. Denison SH, Käfer E, May GS 1993 Mutation in the bimD gene of Aspergillus nidulans confers a conditional mitotic block and sensitivity to DNA damaging agents. Genetics 134:1085-1096
17. Dinardo S, Voelkel K, Sternglanz R 1984 DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication. Proc Natl Acad Sci USA 81:2616-2620
18. Downes CS, Mullinger AM, Johnson RT 1991 Inhibitors of DNA topoisomerase II prevent chromatid separation in mammalian cells but do not prevent exit from mitosis. Proc Natl Acad Sci USA 88:8895-8899
19. Fitzgerald PH, Pickering AF, Mercer JM, Miethke PM 1975 Premature centromere division: a mechanism of non-disjunction causing X chromosome aneuploidy in somatic cells of man. Ann Hum Genet 38:417-428
20. Flemming W 1879 Beiträge zur Kenntnisse der Zelle und ihrer Lebenserscheinungen. Arch Mikrosk Anat 18:151-259
21. Funabiki H, Hagan I, Uzawa S, Yanagida M 1993 Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast. J Cell Biol 121:961-976
22. Funabiki H, Yamano H, Kumada K, Nagao K, Hunt T, Yanagida M 1996a Cut2 proteolysis required for sister-chromatid seperation in fission yeast. Nature 381:438-441
23. Funabiki H, Kumada K, Yanagida M 1996b Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes. EMBO J 15:6617-6628
24. Furuya K, Takahashi K, Yanagida M 1998 Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase. Genes Dev 12:3408-3418
25. Goldstein LS 1980 Mechanisms of chromosome orientation revealed by two meiotic mutants in Drosophila melanogaster. Chromosoma 78:79-111
26. Gorbsky GJ 1994 Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane). Cancer Res 54: 1042-1048
27. Goshima G, Yanagida M 2000 Establishing biorientation occurs with precocious separation of the sister kinetochores, but not the arms, in the early spindle of budding yeast. Cell 100: 619-633
28. Guacci V, Koshland D, Strunnikov A 1997 A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae. Cell 91:47-57
29. Hartwell LH, Weinert TA 1989 Checkpoints: controls that ensure the order of cell cycle events. Science 246:629-634
30. Hirano T 1999 SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates? Genes Dev 13:11-19
31. Hirano T, Mitchison TJ 1994 A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro. Cell 79:449-458
32. Hirano T, Kobayashi R, Hirano M 1997 Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein. Cell 89:511-521
33. Holloway SL, Glotzer M, King RW, Murray AW 1993 Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell 73:1393-1402
34. Irniger S, Piatti S, Michaelis C, Nasmyth K 1995 Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 81:269-278 (erratum: 1998 Cell 93:487)
35. Kerrebrock AW, Moore DP, Wu JS, Orr-Weaver TL 1995 Mei-S332, a Drosophila protein required for sister-chromatid cohesion, can localize to meiotic centromere regions. Cell 83:247-256
36. Khodjakov A, Cole RW, Bajer AS, Rieder CL 1996 The force for poleward chromosome motion in Haemanthus cells acts along the length of the chromosome during metaphase but only at the kinetochore during anaphase. J Cell Biol 132:1093-1104
37. Kimura K, Rybenkov VV, Crisona NJ, Hirano T, Cozzarelli NR 1999 13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation. Cell 98:239-248
38. King RW, Peters JM, Tugendreich S, Rolfe M, Hieter P, Kirschner MW 1995 A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81:279-288
39. Klein F, Mahr P, Galova M et al 1999 A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis. Cell 98:91-103
40. Koshland D, Hartwell LH 1987 The structure of sister minichromosome DNA before anaphase in Saccharomyces cerevisiae. Science 238:1713-1716
41. Kumada K, Nakamura T, Nagao K, Funabiki H, Nakagawa T, Yanagida M 1998 Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis. Curr Biol 8:633-641
42. Lica LM, Narayanswami S, Hamkalo BA 1986 Mouse satellite DNA, centromere structure, and sister chromatid pairing. J Cell Biol 103:1145-1151
43. Lin DC, Grossman AD 1998 Identification and characterization of a bacterial chromosome partitioning site. Cell 92:675-685
44. Losada A, Hirano M, Hirano T 1998 Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev 12:1986-1997
45. Maguire MP 1990 Sister chromatid cohesiveness: vital function, obscure mechanism. Biochem Cell Biol 68:1231-1242
46. Maguire MP, Paredes AM, Riess RW 1991 The desynaptic mutant of maize as a combined defect of synaptonemal complex and chiasma maintenance. Genome 34:879-887
47. May GS, McGoldrick CA, Holt CL, Denison SH 1992 The bimB3 mutation of Aspergillus nidulans uncouples DNA replication from the completion of mitosis. J Biol Chem 267:15737-15743
48. Mazia D 1961 Mitosis and the physiology of cell division. In: Brachet J, Mirsky AE (eds) The cell, vol III. Academic Press, New York, p 77-412
49. McGrew JT, Goetsch L, Byers B, Baum P 1992 Requirement for ESP1 in the nuclear division of Saccharomyces cerevisiae. Mol Biol Cell 3:1443-1454
50. McNeill PA, Berns MW 1981 Chromosome behavior after laser microirradiation of a single kinetochore in mitotic PtK2 cells. J Cell Biol 88:543-553
51. Megee PC, Mistrot C, Guacci V, Koshland D 1999 The centromeric sister chromatid cohesion site directs Mcd1p binding to adjacent sequences. Mol Cell 4:445-450
52. Melander Y 1950 Studies on the chromosomes of Ulophysema oeresundense. Heriditas 36:233-255
53. Melby TE, Ciampaglio CN, Briscoe G, Erickson HP 1998 The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins: long, antiparallel coiled coils, folded at a flexible hinge. J Cell Biol 142:1595-1604
54. Michaelis C, Ciosk R, Nasmyth K 1997 Cohesins: chromosomal proteins that prevent premature separation of sister chromatids. Cell 91:35-45
55. Miyazaki WY, Orr-Weaver TL 1994 Sister chromatid cohesion in mitosis and meiosis. Annu Rev Genet 28:167-187
56. Mole-Bajer J 1958 Cine-micrographic analysis of C-mitosis in endosperm. Chromosoma 9:332-358
57. Murray AW, Szostak JW 1985 Chromosome segregation in mitosis and meiosis. Annu Rev Cell Biol 1:289-315
58. Nicklas RB, Ward SC 1994 Elements of error correction in mitosis: microtubule capture, release, and tension. J Cell Biol 126:1241-1253
59. Nurse P 1990 Universal control mechanism regulating onset of M-phase. Nature 344:503-508
60. Pei L, Melmed S 1997 Isolation and characterization of a pituitary tumor-transforming gene (PTTG). Mol Endocrinol 11:433-441
61. Rattner JB 1991 The structure of the mammalian centromere. Bioessays 13:51-56
62. Rieder CL, Cole R 1999 Chromatid cohesion during mitosis: lessons from meiosis. J Cell Sci 112:2607-2613
63. Rieder CL, Palazzo RE 1992 Colcemid and the mitotic cycle. J Cell Sci 102:387-392
64. Sáez C, Japón MA, Ramos-Morales F et al 1999 hpttg is over-expressed in pituitary adenomas and other primary epithelial neoplasias. Oncogene 18:5473-5476
65. Saka Y, Sutani T, Yamashita Y et al 1994 Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis. EMBO J 13:4938-4952
66. Schrader F 1944 Mitosis. Columbia University Press, New York
67. Selig S, Okumura K, Ward DC, Cedar H 1992 Delineation of DNA replication time zones by fluorescence in situ hybridization. EMBO J 11:1217-1225
68. Shirayama M, Zachariae W, Ciosk R, Nasmyth K 1998 The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. EMBO J 17:1336-1349
69. Shteinberg M, Protopopov Y, Listovsky T, Brandeis M, Hershko A 1999 Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20. Biochem Biophys Res Commun 260:193-198
70. Sigrist S, Jacobs H, Stratmann R, Lehner CF 1995 Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. EMBO J 14:4827-4838
71. Skibbens RV, Corson LB, Koshland D, Hieter P 1999 Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery. Genes Dev 13:307-319
72. Stratmann R, Lehner CF 1996 Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition. Cell 84:25-35
73. Sumner AT 1991 Scanning electron microscopy of mammalian chromosomes from prophase to telophase. Chromosoma 100:410-418
74. Surana U, Amon A, Dowzer C, McGrew J, Byers B, Nasmyth K 1993 Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J 12:1969-1978
75. Tanaka K, Yonekawa T, Kawasaki Y et al 2000 Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase. Mol Cell Biol 20:3459-3469
76. Tanaka T, Cosma MP, Wirth K, Nasmyth K 1999 Identification of cohesin association sites at centromeres and along chromosome arms. Cell 98:847-858
77. Tippit DH, Pickett-Heaps JD, Leslie R 1980 Cell division in two large pennate diatoms Hantzschia and Nitzschia III. A new proposal for kinetochore function during prometaphase. J Cell Biol 86:402-416
78. Tomkins D, Hunter A, Roberts M 1979 Cytogenetic findings in Roberts-SC phocomelia syndrome(s). Am J Med Genet 4:17-26
79. Tomonaga T, Nagao K, Kawasaki Y et al 2000 Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase. Genes Dev 14:2757-2770
80. Tóth A, Ciosk R, Uhlmann F, Galova M, Schleiffer A, Nasmyth K 1999 Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication. Genes Dev 13:320-333
81. Uhlmann F, Nasmyth K 1998 Cohesion between sister chromatids must be established during DNA replication. Curr Biol 8:1095-1101
82. Uhlmann F, Lottspeich F, Nasmyth K 1999 Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1. Nature 400:37-42
83. van Heemst D, James F, Pöggeler S, Berteaux-Lecellier V, Zickler D 1999 Spo76p is a conserved chromosome morphogenesis protein that links the mitotic and meiotic programs. Cell 98:261-271
84. Vig BK 1981 Sequence of centromere separation: analysis of mitotic chromosomes in man. Hum Genet 57:247-252
85. Waizenegger IC, Hauf S, Meinke A, Peters J-M 2000 Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell 103:399-410
86. Watson JD, Crick FHC 1953 Genetic implications of the structure of deoxyribonucleic acid. Nature 171:964-967
87. Weinstein J 1997 Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1. J Biol Chem 272:28501-28511
88. Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH 1997 Viable offspring derived from fetal and adult mammalian cells. Nature 385:810-813 (erratum: 1997 Nature 386:200)
89. Wilson EB 1925 The cell in development and heredity, 3rd edn. The Macmillan Co., New York
90. Yamamoto A, Guacci V, Koshland D 1996a Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). J Cell Biol 133:99-110
91. Yamamoto A, Guacci V, Koshland D 1996b Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae. J Cell Biol 133:85-97
92. Zachariae W, Nasmyth K 1999 Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev 13:2039-2058
93. Zou H, McGarry TJ, Bernal T, Kirschner MW 1999 Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science 285:418-422