Nitrative stress in cerebral endothelium is mediated by mGluR5 in hyperhomocysteinemia

Journal of Cerebral Blood Flow and Metabolism

Volumn 32, Issue 5, 2012, Pages 825-834

  Mayo, Jamie N ^a   Beard, Richard S ^a   Price, Tulin O ^b   Chen, Cheng Hung ^a   Erickson, Michelle A ^c,d   Ercal, Nuran ^e   Banks, William A ^c,d   Bearden, Shawn E ^a  

^a Nucl Eng Idaho State University   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e MISSOURI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (United States)

Author keywords

blood brain barrier; homocysteine; microvascular; oxidative stress; peroxynitrite

Indexed keywords

3 NITROTYROSINE; HOMOCYSTEINE; INDUCIBLE NITRIC OXIDE SYNTHASE; METABOTROPIC RECEPTOR 5; NITRIC OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HYPERHOMOCYSTEINEMIA; INTRACELLULAR SIGNALING; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NEUROPATHOLOGY; NITRATIVE STRESS; NITROSYLATION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RECEPTOR BLOCKING; RECEPTOR UPREGULATION; WILD TYPE;

AMIDINES; ANIMALS; BENZYLAMINES; BRAIN; ENDOTHELIUM; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCINE; HOMOCYSTEINE; HYPERHOMOCYSTEINEMIA; MICE; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHENYLACETATES; RECEPTORS, METABOTROPIC GLUTAMATE; STRESS, PHYSIOLOGICAL; TYROSINE;

EID: 84860457412     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.185     Document Type: Article

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