IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action

Cell Metabolism

Volumn 15, Issue 5, 2012, Pages 703-712

  Sadagurski, Marianna ^a   Leshan, Rebecca L ^b   Patterson, Christa ^b   Rozzo, Aldo ^a   Kuznetsova, Alexandra ^a   Skorupski, Josh ^b   Jones, Justin C ^b   Depinho, Ronald A ^c   Myers, Martin G ^b   White, Morris F ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LEPTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARCUATE NUCLEUS; ARTICLE; BRAIN METABOLISM; BRAIN NERVE CELL; CONTROLLED STUDY; ENDOCRINE FUNCTION; ENERGY BALANCE; ENERGY EXPENDITURE; FOXO1 GENE; GENE; GENE DELETION; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; HORMONE ACTION; HORMONE SENSITIVITY; HYPOTHALAMUS; INSULIN RECEPTOR SUBSTRATE 2 GENE; INSULIN RESISTANCE; LEPTIN RECEPTOR B GENE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RECEPTOR GENE; SIGNAL TRANSDUCTION;

MUS;

EID: 84860451500     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.04.011     Document Type: Article

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