Effects of hecogenin and its possible mechanism of action on experimental models of gastric ulcer in mice

European Journal of Pharmacology

Volumn 683, Issue 1-3, 2012, Pages 260-269

  Santos Cerqueira, Gilberto ^a   Dos Santos E Silva, Gabriela ^a   Rios Vasconcelos, Emiliano ^a   Fragoso De Freitas, Ana Paula ^a   Arcanjo Moura, Brinell ^a   Silveira MacEdo, Danielle ^a   Lopes Souto, Augusto ^b   Barbosa Filho, José Maria ^b   De Almeida Leal, Luzia Kalyne ^a   De Castro Brito, Gerly Anne ^a   Souccar, Caden ^c   De Barros Viana, Glauce Socorro ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Agave sisalana; Antiulcerogenic activity; Gastroprotection mechanism of action; Hecogenin; Steroid saponin

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CYCLOOXYGENASE 2; GLUTATHIONE; HECOGENIN; MYELOPEROXIDASE; NITRIC OXIDE; NITRITE; PROSTAGLANDIN; RANITIDINE; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIULCER ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME RELEASE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; PROTEIN EXPRESSION; SISAL; STOMACH MUCOSA; STOMACH PROTECTION; STOMACH ULCER;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTI-ULCER AGENTS; ANTIOXIDANTS; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GLUTATHIONE; HUMANS; INDOMETHACIN; KATP CHANNELS; LIPID PEROXIDATION; MALE; MICE; NEUTROPHIL ACTIVATION; NITRIC OXIDE; PROSTAGLANDINS; RANDOM ALLOCATION; SAPOGENINS; STOMACH; STOMACH ULCER;

EID: 84860448124     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.02.043     Document Type: Article

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