Gastroprotective activity of isopulegol on experimentally induced gastric lesions in mice: Investigation of possible mechanisms of action

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 380, Issue 3, 2009, Pages 233-245

  Silva, Maria Izabel Gomes ^a   Moura, Brinell Arcanjo ^a   De Aquino Neto, Manuel Rufino ^a   Da Rocha Tomé, Adriana ^b   Rocha, Nayrton Flávio Moura ^a   De Carvalho, Alyne Mara Rodrigues ^a   MacÊdo, Danielle Silveira ^a   Vasconcelos, Silvânia Maria Mendes ^a   De Sousa, Damião Pergentino ^c   De Barros Viana, Glauce Socorro ^a   De Sousa, Francisca Cléa Florenço ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b STATE UNIVERSITY OF CEARÁ   (Brazil)

^c FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

Action mechanisms; Antiulcerogenic activity; Isopulegol; Monoterpene

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ALCOHOL; ANTIULCER AGENT; GLIBENCLAMIDE; GLUTATHIONE; INDOMETACIN; ISOPULEGOL; N(G) NITRO DEXTRO ARGININE METHYL ESTER; NITRIC OXIDE; PROSTAGLANDIN; TERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG MECHANISM; HISTOPATHOLOGY; MALE; MOUSE; NONHUMAN; STOMACH PROTECTION; STOMACH ULCER;

ANIMALS; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GLUTATHIONE; INDOMETHACIN; KATP CHANNELS; MALE; MICE; PROSTAGLANDINS; STOMACH ULCER; TERPENES;

EID: 68349108039     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-009-0429-5     Document Type: Article

References (66)

1. EO Adeyemi SA Bastaki IS Chandranath 2005 Mechanisms of action of leptin in preventing gastric ulcer World J Gastroenterol 11 27 4154 4160
2. RN Almeida DS Navarro JM Barbosa-Filho 2001 Plants with central analgesic activity Phytomedicine 8 310 322
3. JF Amaral MIG Silva MR Aquino Neto 2007 Antinociceptive effect of the monoterpene R-(+)-limonene in mice Biol Pharm Bull 30 7 1217 1220
4. SF Andrade M Lemosa E Comunello 2007 Evaluation of the antiulcerogenic activity of Maytenus robusta (Celastraceae) in different experimental ulcer models J Ethnopharmacol 113 252 257
5. KP Bhargava MB Gupta KK Tangri 1973 Mechanism of ulcerogenic activity of indomethacin and oxyphenbutazone Eur J Pharmacol 22 2 191 195
6. SP Bhatia D McGinty CS Letizia 2008 Fragrance material review on isopulegol Food Chem Toxicol 46 S185 S189
7. T Brzozowski PC Konturek D Drozdowicz 2005 Grapefruit-seed extract attenuates ethanol- and stress-induced gastric lesions via activation of prostaglandin, nitric oxide and sensory nerve pathways World J Gastroenterol 11 6450 6458
8. SI Chandranath SMA Bastaki JA Singh 2002 Comparative study on the activity of lansoprazole, omeprazole and PD-136450 on acidified ethanol- and indomethacin-induced gastric lesions in the rat Clin Exp Pharmacol Physiol 29 3 173 180
9. GK Chuah SH Liu S Jaenicke LJ Harrison 2001 Cyclisation of citronellal to isopulegol catalysed by hydrous zirconia and other solid acids J Catal 200 352 359
10. F Da Rocha Lapa CS Freitas CH Baggio 2007 Gastroprotective activity of the hydroalcoholic extract obtained from Polygala paniculata L. in rats J Pharm Pharmacol 59 10 1413 1419
11. FC De Sousa AP Monteiro CT de Melo 2005 Antianxiety effects of riparin I from Aniba riparia (Nees) Mez (Lauraceae) in mice Phytother Res 19 12 1005 1008
12. DP De Sousa JCR Gonçalves L Quintans-Júnior 2006 Study of anticonvulsant effect of citronellol, a monoterpene alcohol, in rodents Neurosci Lett 401 231 235
13. DP De Sousa FFF Nóbrega FS Claudino 2007 Pharmacological effects of the monoterpene a, b-epoxy-carvone in mice Rev Bras Farmacogn 17 2 170 175
14. DP De Sousa E Raphael U Brocksom 2007 Sedative effect of monoterpene alcohols in mice: a preliminary screening Z Naturforsch C 62 7-8 563 566
15. S Demir M Yilmaz M Köseoǧlu 2003 Role of free radicals in peptic ulcer and gastritis Turk J Gastroenterol 14 1 39 43
16. ML Garcia M Hanner HG Knaus 1997 Pharmacology of potassium channels Adv Pharmacol 39 425 471
17. AS Gomes LMF Lima CL Santos 2006 LPS from E. coli protects indomethacin-induced gastrophaty in rats-role of ATP-sensitive K channels Eur J Pharmacol 547 1-3 136 142
18. MM Guedes AC Carvalho AF Lima 2008 Gastroprotective mechanisms of centipedic acid, a natural diterpene from Egletes viscosa LESS Biol Pharm Bull 31 7 1351 5
19. V Gürbüz I Alican Berrak 1999 Role of nitric oxide in indomethacin-induced gastric mucosal dysfunction in the rat Exp Physiol 84 2 319 332
20. F Iwata A Koo M Itoh 1997 Functional evidence linking potassium channels and afferent nerve-mediated mucosal protection in rat stomach Life Sci 61 17 1713 1720
21. R Jaszewski DY Graham SC Stromatt 1992 Treatment of nonsteroidal antiinflammatory drug-induced gastric ulcers with misoprostol Dig Dis Sci 37 12 1820 1824
22. SJ Kim YS Jung DY Kwon 2008 Alleviation of acute ethanol-induced liver injury and impaired metabolomics of S-containing substances by betaine supplementation Biochem Biophys Res Commun 368 4 893 898
23. T Kunikata H Araki M Takeeda 2001 Prostaglandin E prevents indomethacin-induced gastric and intestinal damage through different EP receptor subtypes J Physiol Paris 95 1-6 157 163
24. L Laine WM Weinstein 1988 Histology of alcoholic hemorrhagicgastritis: a prospective evaluation Gastroenterology 94 1254 1262
25. Y Li WP Wang HY Wang 2000 Intragastric administration of heparin enhances gastric ulcer healing through a nitric oxide dependent mechanism in rats Eur J Pharmacol 399 205 214
26. H Lowry NJ Rosebrough AL Farr 1951 Protein measurements with the folin phenol reagent J Biol Chem 193 265 275
27. S Maity JR Vedasiromoni DK Ganguly 1998 Role of glutathione in the antiulcer effect of hot water extract of black tea (Camellia sinensis) Jpn J Pharmacol 78 3 285 292
28. E Masuda S Kawano K Nagano 1995 Endogenous nitric oxide modulates ethanol-induced gastric mucosal injury in rats Gastroenterology 108 1 58 64
29. H Matsuda Y Pongpiriyadacha T Morikawa 2002 Protective effects of polygodial and related compounds on ethanol-induced gastric mucosal lesions in rats: structural requirements and mode of action Bioorg Med Chem Lett 12 3 477 482
30. T Matsunaga C Hasegawa T Kawasuji 2000 Isolation of the antiulcer compound in essential oil from the leaves of Cryptomeria japonica Biol Pharm Bull 23 595 598
31. JV Medeiros GG Gadelha SJ Lima 2008 Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats Br J Pharmacol 153 4 623 624
32. A Meister 1991 Glutathione deficiency produced by inhibition of its synthesis, and its reversal: applications in research and therapy Pharmacol Ther 51 155 194
33. V Molina D Carbajal L Arruzazabala 2005 Therapeutic effect of D-002 (Abexol) on gastric ulcer induced experimentally in rats J Med Food 8 1 59 62
34. H Mutoh H Hiraishi S Ota 1990 Role of oxygen radicals in ethanol-induced damage to cultured gastric mucosal cells Am J Physiol 258 603 609
35. M Nogami T Moriura M Kubo 1986 Studies on the origin, processing and quality of crude drugs. II: Pharmacological evaluation of the Chinese crude drug "Zhu" in experimental stomach ulcer. (2). Inhibitory effect of extract of Atractylodes lancea on gastric secretion Chem Pharml Bull 34 3854 3860 (Pubitemid 17192775)
36. Y Ohtau T Kobayashi I Ishiguro 1999 Role of endogenous serotonin and histamine in the pathogenesis of gastric mucosal lesions in unanaesthetised rats with a single treatment of compound 48/80, a mast cell degranulator Pharmacol Res 39 4 261 267 (Pubitemid 29182324)
37. TM Olinda TLG Lemos LL Machado 2008 Quebrachitol-induced gastroprotection against acute gastric lesions: role of prostaglandins, nitric oxide and K+ ATP channels Phytomedicine 15 327 333
38. FA Oliveira GM Vieira-Júnior MH Chaves 2004 Gastroprotective and anti-inflammatory effects of resin from Protium heptaphyllum in mice and rats Pharmacol Res 49 105 111
39. SY Paik KH Kok SM Beak 2005 The essential oils from Zanthoxylum schinifolium pericarp induce apoptosis of HepG2 human hepatoma cells through increased production of reactive oxygen species Biol Pharm Bull 28 5 802 807
40. AC Paula W Toma JS Gracioso 2006 The gastroprotective effect of the essential oil of Croton cajucara is different in normal rats than in malnourished rats Br J Nutr 96 2 310 315
41. BM Peskar K Ehrlich BA Peskar 2002 Role of ATP-sensitive potassium channels in prostaglandin-mediated gastroprotection in the rat J Pharmacol Exp Ther 301 969 974
42. Y Pongpiriyadacha H Matsuda T Morikawa 2003 Protective effects of polygodial on gastric mucosal lesions induced by necrotizing agents in rats and the possible mechanisms of action Biol Pharm Bull 26 5 651 657
43. KD Rainsford 1978 Structure-activity relationships of non-steroid anti-inflammatory drug gastric ulcerogenic activity Agents Actions 8 6 587 605
44. KD Rainsford 1987 The effect of 5-lipoxygenase inhibitors and leukotriene antagonists on the development of gastric lesions induced by nonsteroidal antiinflammatory drugs in mice Agents Action 21 316 319
45. BRR Rao PN Kaul KY Syamasundar 2003 Comparative composition of decanted and recovered essential oils of Eucalyptus citriodora Hook Flav Frag J 18 133 135
46. A Robert JE Nezamis C Lancaster 1979 Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury Gastroenterology 77 3 433 443
47. JA Rodríguez C Theoduloz M Sánchez 2005 Gastroprotective activity of a new semisynthetic solidagenone derivative in mice J Pharm Pharmacol 57 2 265 271
48. M Sánchez C Theoduloz G Schmeda-Hirschmann 2006 Gastroprotective and ulcer-healing activity of oleanolic acid derivatives: in vitro-in vivo relationships Life Sci 79 1349 1356
49. CL Santos MH Souza AS Gomes 2005 Sildenafil prevents indomethacin-induced gastropathy in rats: role of leukocyte adherence and gastric blood flow Br J Pharmacol 146 4 481 486
50. J Sedlak RH Lindsay 1968 Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellmańs reagent Anal Biochem 25 1 192 205
51. S Serra E Brenna C Fuganti 2003 Lipase-catalyzed resolution of p-menthan-3-ols monoterpenes: preparation of the enantiomer-enriched forms of menthol, isopulegol, trans- and cis-piperitol, and cis-isopiperitenol Tetrahedron: Asymmetry 14 3313 3319
52. MIG Silva MR de Aquino Neto PF Teixeira Neto 2007 Central nervous system activity of acute administration of isopulegol in mice Pharmacol Biochem Behav 88 2 141 147
53. FC Sousa CT Melo AP Monteiro 2004 Antianxiety and antidepressant effects of riparin III from Aniba riparia (Nees) Mez (Lauraceae) in mice Pharmacol Biochem Behav 78 1 27 33
54. H Speisky A MacDonald G Giles 1985 Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies Biochem J 225 3 565 572
55. Y Sugai T Ando G Nishimura 1968 Sulfhydryl group (total SH) and glutathione contents in digestive organs J Gastroenterol 3 4 280 281
56. J Sun 2007 D-Limonene: safety and clinical applications Altern Med Rev 2 3 259 263
57. S Szabo JS Trier A Brown 1985 A quantitative method for assessing the extent of experimental gastric erosions and ulcers J Pharmacol Methods 13 1 59 66
58. H Takase K Yamamoto H Hirano 1994 Pharmacological profile of gastric mucosal protection by marmim and nobiletim from traditional herbal medicine, Aurantii fructus immaturus Jpn J Pharmacol 66 139 147
59. JS Trier S Szabo CH Allan 1987 Ethanol-induced damage to mucosal capillaries of rat stomach. Ultrastructural features and effects of prostaglandin E2 and cysteamine Gastroenterology 92 13 22
60. GA Vernin C Parkanyi F Cozzolino 2004 GC/MS analysis of the volatile constituents of Corymbia citriodora Hook. from Réunion Island J Essent Oil Res 16 560 565
61. JL Wallace DN Granger 1996 The cellular and molecular basis of gastric mucosal defense FASEB J 10 731 740
62. M Yeo DK Kim SW Cho 2008 Ginseng, the root of Panax ginseng C.A. Meyer, protects ethanol-induced gastric damages in rat through the induction of cytoprotective heat-shock protein 27 Dig Dis Sci 53 606 613
63. M Yoshikawa S Sugimoto S Nakamura 2007 Medicinal flowers. XVI. New dammarane-type triterpene tetraglycosides and gastroprotective principles from flower buds of Panax ginseng Chem Pharm Bull 55 7 1034 1038 (Pubitemid 47026539)
64. K Yu SF Jiang MF Lin 2004 Extraction and purification of biologically active intestinal trefoil factor from human meconium Lab Invest 84 390 392
65. W Zhao F Zhu W Shen 2009 Protective effects of DIDS against ethanol-induced gastric mucosal injury in rats Acta Biochim Biophys Sin 41 4 301 308
66. M Zimmerman 1983 Ethical guidelines for investigations of experimental pain in conscious animals Pain 16 109 110