Antiulcerogenic effect of Securigera securidaca L. Seed extract on various experimental gastric ulcer models in rats

Pakistan Journal of Biological Sciences

Volumn 11, Issue 23, 2008, Pages 2619-2623

  Mard, Seyyed Ali ^a   Bahari, Z ^a   Eshaghi, N ^a   Farbood, Y ^a  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Rat; Securigera securidaca; Water immersion restraint stress

Indexed keywords

CORONILLA SECURIDACA; FABACEAE; RATTUS; SECURIDACA;

ANTIULCER AGENT; PLANT EXTRACT;

ANIMAL; ARTICLE; CHEMISTRY; DRUG EFFECT; LEGUME; MALE; PHYTOTHERAPY; PLANT SEED; RAT; STOMACH MUCOSA; STOMACH ULCER; ULCER; WISTAR RAT;

ANIMALS; ANTI-ULCER AGENTS; FABACEAE; GASTRIC MUCOSA; MALE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; SEEDS; STOMACH ULCER; ULCER;

EID: 68349148674     PISSN: 10288880     EISSN: 18125735     Source Type: Journal    
DOI: 10.3923/pjbs.2008.2619.2623     Document Type: Article

References (21)

1. Ali, A.A., M.H. Mohamed, M. S, Kamel, M.A. Fouad and O. Spring, 1998. Studies on Securigera securidaca (L.) Deg. et Dorfl. (Fabaceae) seeds, an antidiabetic Egyptian folk medicine. Pharmazie, 53: 710-715.
2. Alvarez, A., A. Pomar, M.A. Sevilla and M.J. Montero, 1999. Gastric antisecretory and antiulcer activities of an ethanolic extract of Bidens pilosa L. var. radiata Schult. Bip. J. Ethnopharmacol., 67: 333-340.
3. Berenguer, B., L.M. Sanchez, A. Qui-lez, M. Lopez-Barreiro, O. De Haro, J. Galvez and M.J. Martín, 2006. Protective and antioxidant effects of Rhizophora mangle L. against NSAID-induced gastric ulcers. J. Ethnopharmacol., 103: 194-200.
4. Gharib Naseri, M.K. and S.A. Mard, 2007. Gastroprotecttive effect of Alhagi maurorum on experimental gastric ulcer rats. Pak. J. Med. Sci., 23: 570-573.
5. Gilani, A.H., A.U. Khan, T. Ali and S. Ajmal, 2008. Mechanisms underlying the antispasmodic and bronchodilatory properties of Terminalia bellerica fruit. J. Ethnopharmacol., 116: 528-538.
6. Hoogerwerf, W.A. and P.J. Pasricha, 2001. Agents Used for Control of Gastric Acidity and Treatment of Peptic Ulcers and Gastroesophageal Reflux Disease. In: Goodman and Gilamans The Pharmacological Basis of Therapeutics, Hardman, J.G. and L.E. Limbird (Eds.). McGraw-Hill, New York, pp: 1005-1019.
7. Hosseinzadeh, H., M. Ramezani and R. Danaei, 2002. Antihyperglycemic effect and Acute Toxicity of Securigera securidaca L. seed extracts in mice. Phytother Res., 16: 745-747.
8. Konturek, S.J., P.C. Konturek, T. Brzozowski, J.W. Konturek and W.W. Pawlik, 2005. From nerves and hormones to bacteria in the stomach; nobel prize for achievements in gastrology during last century. J. Physiol Pharmacol., 56: 507-530.
9. Manonmani, S., V.P. Viswanathan, S. Subramanian and S. Govindasamy, 1995. Biochemical studies on the antiulcerogenic activity of cauvery 100, an ayurvedic formulation in experimental ulcers. Indian J. Pharmacol., 27: 101-105.
10. Nagarajan, S., H.C. Jain and G.S. Aulakh, 1982. Indigenous Plants Used in the Control of Diabetes. In: Research Laboratory Cultivation and Utilization of Medicinal Plants, Atal, C.K. and B.M. Kapur (Eds.). PID CSJR, Jammu Tawi, pp: 584-604.
11. Nash, J., L. Lambert and M. Deakin, 1994. Histamine H2-receptor antagonists in peptic ulcer disease. Evidence for a prophylactic use. Drugs, 47: 862-871.
12. Nguelefack, T.B., C.B. Feumebo, G. Ateufack, P. Watcho and S. Tatsimo et al., 2008. Anti-ulcerogenic properties of the aqueous and methanol extracts from the leaves of Solanum torvum Swartz (Solanaceae) in rats. J. Ethnopharmacol., 119: 135-140.
13. Perera, L.M.S., D. Ruedas and B.C. Gomez, 2001. Gastric antiulcer effect of Rhizophora mangle L. J. Ethnopharmacol., 77: 1-3.
14. Reyes, M., C. Martin, C. Alarcon de la Lastra, J. Trujillo, M.V. Toro and M.J. Ayuso, 1996. Antiulcerogenicity of the flavonoid fraction fromErica andevalensis cabezudo-rivera. Z Naturforsch [C]., 51: 563-569.
15. Sairam, K., C.V. Rao, M.D. Babu, K.V. Kumar, V.K. Agrawal and R.K. Goel, 2002. Antiulcerogenic effect of methanolic extract of Emblica officinalis: An experimental study. J. Ethnopharmacol., 82: 1-9.
16. Schubert, M.L., 2004. Gastric secretion. Curr. Opin. Gastroenterol., 20: 519-525.
17. Twardowschy, A., C.S. Freitas, C.H. Baggio, B. Mayer and A.C. dos Santos et al., 2008. Antiulcerogenic activity of bark extract ofTabebuia avellanedae, lorentz ex griseb. J. Ethnopharmacol., 118: 455-459.
18. Valle, J.D., 2005. Peptic Ulcer Diseases and Related Disorders. In: Harrison's Principles of Internal Medicine, Braunwald, A.S., D.L. Fauci, S.L. Kasper, D.L. Hauser, Longo and J.L. Jameson (Eds.). 16th Edn., McGraw-Hill, New York, pp: 1746-1762.
19. Vallet, J., J.M. Rovanet and P. Besancon, 1994. Dietary grape seed tannins. Effects on nutritional balance and on some ensymic activities along the crypt-villus axis of rat small intestine. Ann. Nutr. Metab., 38: 75-84.
20. Xing, L., M. Anne, A.M. Karinch and G.L. Kauffman, 1998. Mesolimbic expression of neurotensin and neurotensin receptor during stress-induced gastric mucosal injury. Am. J. Physiol., 274: 38-45.
21. 7. Chem. Pharm. Bull., 53: 1559-1564.