Short-term exposure of 4-hydroxynonenal induces mitochondria-mediated apoptosis in PC12 cells

Human and Experimental Toxicology

Volumn 31, Issue 4, 2012, Pages 336-345

  Siddiqui, M A ^a   Kumar, V ^b   Kashyap, M P ^b   Agarwal, M ^b   Singh, A K ^b   Khanna, V K ^b   Al Khedhairy, A A ^a   Musarrat, J ^a   Pant, A B ^b   Jahan, S ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

4 hydroxynonenal; apoptosis; PC12 cells; reactive oxygen species (ROS)

Indexed keywords

4 HYDROXYNONENAL; BETA ACTIN; CASPASE 3; MESSENGER RNA; NEUROMODULIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C FOS; PROTEIN C JUN; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL STRAIN; DOWN REGULATION; ENZYME ACTIVITY; EXPOSURE; GENE EXPRESSION; LIPID PEROXIDATION; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ALDEHYDES; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CASPASE 3; CELL CULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; GAP-43 PROTEIN; MITOCHONDRIA; NEURONS; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 84860427093     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327111432500     Document Type: Article

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