The effects of 3, 4 or 5 amino salicylic acids on manganese-induced neuronal death: ER stress and mitochondrial complexes

Toxicology in Vitro

Volumn 25, Issue 7, 2011, Pages 1259-1268

  Yoon, Hyonok ^a,c   Lee, Geum Hwa ^a   Kim, Do Sung ^a   Kim, Kee Won ^a   Kim, Hyung Ryong ^b   Chae, Han Jung ^a  

^a Chonbuk National University   (South Korea)

^b Wonkwang University   (South Korea)

^c HOWARD UNIVERSITY   (United States)

Author keywords

3, 4, 5 ASA; ER stress; Manganese (Mn); Mitochondrial complex activity; Mitochondrial membrane potential; ROS

Indexed keywords

AMINOSALICYLIC ACID; CYTOCHROME C OXIDASE; MANGANESE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL TOXICITY; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ACETYLCYSTEINE; AMINOSALICYLIC ACIDS; ANTIOXIDANTS; CELL DEATH; CELL LINE, TUMOR; ELECTRON-TRANSFERRING FLAVOPROTEINS; ENDOPLASMIC RETICULUM STRESS; HUMANS; MANGANESE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEURONS;

EID: 84860417259     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.04.002     Document Type: Article

References (44)

1. Asanuma M., Miyazaki I., Ogawa N. Neuroprotective effects of non- steroidal anti-inflammatory drugs on neurodegenerative diseases. Curr. Pharm. Des. 2004, 10:695-700.
2. Aschner M., Erikson K.M., Dorman D.C. Manganese dosimetry: species differences and implications for neurotoxicity. Crit. Rev. Toxicol. 2005, 35:1-32.
3. Autissier N., Dumas P., Brosseau J., Loireau A. Effects of methylcyclopentadienyl manganese tricarbonyl (MMT) of rat liver mitochondria. I. Effects, in vitro, on the oxidative phosphorylation (author's transl). Toxicology 1977, 7:115-122.
4. Autissier N., Gautheron B., Dumas P., Brosseau J., Loireau A. Effects of methylcyclopentadienyl manganese tricarbonyl (MMT) on rat liver mitochondria. II. Activity-structure relation (author's transl). Toxicology 1977, 8:125-133.
5. Barbeau A. Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias. Neurotoxicology 1984, 5:13-35.
6. Brooks K.J., Hargreaves I.P., Bates T.E. Nitric-oxide-induced inhibition of mitochondrial complexes following aglycaemic hypoxia in neonatal cortical rat brain slices. Dev. Neurosci. 2000, 22:359-365.
7. Chun H.S., Lee H., Son J.H. Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741. Neurosci. Lett. 2001, 316:5-8.
8. Dieteren C.E., Willems P.H., Vogel R.O., Swarts H.G., Fransen J., Roepman R., Crienen G., Smeitink J.A., Nijtmans L.G., Koopman W.J. Subunits of mitochondrial complex I exist as part of matrix- and membrane-associated subcomplexes in living cells. J. Biol. Chem. 2008, 283:34753-34761.
9. Gavin C.E., Gunter K.K., Gunter T.E. Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity. Biochem. J. 1990, 266:329-334.
10. Gonzalez L.E., Juknat A.A., Venosa A.J., Verrengia N., Kotler M.L. Manganese activates the mitochondrial apoptotic pathway in rat astrocytes by modulating the expression of proteins of the Bcl-2 family. Neurochem. Int. 2008, 53:408-415.
11. Gunter R.E., Puskin J.S., Russell P.R. Quantitative magnetic resonance studies of manganese uptake by mitochondria. Biophys. J. 1975, 15:319-333.
12. Herold C., Ocker M., Ganslmayer M., Gerauer H., Hahn E.G., Schuppan D. Ciprofloxacin induces apoptosis and inhibits proliferation of human colorectal carcinoma cells. Br. J. Cancer 2002, 86:443-448.
13. Herrero Hernandez E., Discalzi G., Dassi P., Jarre L., Pira E. Manganese intoxication: the cause of an inexplicable epileptic syndrome in a 3 year old child. Neurotoxicology 2003, 24:633-639.
14. Huang H., Manton K.G. The role of oxidative damage in mitochondria during aging: a review. Front Biosci. 2004, 9:1100-1117.
15. Janetzky B., Hauck S., Youdim M.B., Riederer P., Jellinger K., Pantucek F., Zochling R., Boissl K.W., Reichmann H. Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease. Neurosci. Lett. 1994, 169:126-128.
16. Jiang Y.M., Mo X.A., Du F.Q., Fu X., Zhu X.Y., Gao H.Y., Xie J.L., Liao F.L., Pira E., Zheng W. Effective treatment of manganese-induced occupational Parkinsonism with p-aminosalicylic acid: a case of 17year follow-up study. J. Occup. Environ. Med. 2006, 48:644-649.
17. Katayama T., Imaizumi K., Honda A., Yoneda T., Kudo T., Takeda M., Mori K., Rozmahel R., Fraser P., George-Hyslop P.S., Tohyama M. Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations. J. Biol. Chem. 2001, 276:43446-43454.
18. Kazi T.G., Afridi H.I., Kazi N., Jamali M.K., Arain M.B., Jalbani N., Kandhro G.A. Copper, chromium, manganese, iron, nickel, and zinc levels in biological samples of diabetes mellitus patients. Biol. Trace Elem. Res. 2008, 122:1-18.
19. Kim D.S., Kim H.R., Woo E.R., Hong S.T., Chae H.J., Chae S.W. Inhibitory effects of rosmarinic acid on adriamycin-induced apoptosis in H9c2 cardiac muscle cells by inhibiting reactive oxygen species and the activations of c-Jun N-terminal kinase and extracellular signal-regulated kinase. Biochem. Pharmacol. 2005, 70:1066-1078.
20. King T.S. " Preparation of succinate cytochrome c reductase, and the cytochrome b-c particle and reconstitution of succinate cytochrome c reductase. Methods Enzymol. 1967, 10:328-333.
21. Kitazawa M., Wagner J.R., Kirby M.L., Anantharam V., Kanthasamy A.G. Oxidative stress and mitochondrial-mediated apoptosis in dopaminergic cells exposed to methylcyclopentadienyl manganese tricarbonyl. J. Pharmacol. Exp. Ther. 2002, 302:26-35.
22. Lee A.H., Iwakoshi N.N., Glimcher L.H. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol. Cell Biol. 2003, 23:7448-7459.
23. Lee G.H., Kim H.K., Chae S.W., Kim D.S., Ha K.C., Cuddy M., Kress C., Reed J.C., Kim H.R., Chae H.J. Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression. J. Biol. Chem. 2007, 282:21618-21628.
24. Ljung K., Vahter M. Time to re-evaluate the guideline value for manganese in drinking water?. Environ. Health Perspect. 2007, 115:1533-1538.
25. Milatovic D., Zaja-Milatovic S., Gupta R.C., Yu Y., Aschner M. Oxidative damage and neurodegeneration in manganese-induced neurotoxicity. Toxicol. Appl. Pharmacol. 2009, 240:219-225.
26. Olanow C.W. Manganese-induced parkinsonism and Parkinson's disease. Ann. NY Acad. Sci. 2004, 1012:209-223.
27. Olanow C.W., Good P.F., Shinotoh H., Hewitt K.A., Vingerhoets F., Snow B.J., Beal M.F., Calne D.B., Perl D.P. Manganese intoxication in the rhesus monkey: a clinical, imaging, pathologic, and biochemical study. Neurology 1996, 46:492-498.
28. Pabbruwe M.B., Standard O.C., Sorrell C.C., Howlett C.R. Bone formation within alumina tubes: effect of calcium, manganese, and chromium dopants. Biomaterials 2004, 25:4901-4910.
29. Pfaffenbach K.T., Gentile C.L., Nivala A.M., Wang D., Wei Y., Pagliassotti M.J. Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death. Am. J. Physiol. Endocrinol. Metab. 2010, 298:E1027-1035.
30. Pfaffenbach K.T., Lee A.S. The critical role of GRP78 in physiologic and pathologic stress. Curr Opin Cell Biol. 2011, 23(2):150-156.
31. Prabhakaran K., Ghosh D., Chapman G.D., Gunasekar P.G. Molecular mechanism of manganese exposure-induced dopaminergic toxicity. Brain Res. Bull. 2008, 76:361-367.
32. Reed J.S., Ragan C.I. The effect of rate limitation by cytochrome c on the redox state of the ubiquinone pool in reconstituted NADH: cytochrome c reductase. Biochem. J. 1987, 247:657-662.
33. Rutkowski D.T., Kaufman R.J. A trip to the ER: coping with stress. Trends Cell Biol. 2004, 14:20-28.
34. Ryu E.J., Harding H.P., Angelastro J.M., Vitolo O.V., Ron D., Greene L.A. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J. Neurosci. 2002, 22:10690-10698.
35. Sagone A.L., Husney R.M., O'Dorisio M.S., Metz E.N. Mechanisms for the oxidation of reduced gluthathione by stimulated granulocytes. Blood 1984, 63:96-104.
36. Schapira A.H., Cooper J.M., Dexter D., Clark J.B., Jenner P., Marsden C.D. Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 1990, 54:823-827.
37. Shults C.W. Mitochondrial dysfunction and possible treatments in Parkinson's disease-a review. Mitochondrion 2004, 4:641-648.
38. Strause L., Saltman P., Smith K.T., Bracker M., Andon M.B. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. J. Nutr. 1994, 124:1060-1064.
39. Suzuki S., Yoshioka N., Isshiki N., Hamanaka H., Miyachi Y. Involvement of reactive oxygen species in post-ischaemic flap necrosis and its prevention by antioxidants. Br. J. Plast. Surg. 1991, 44:130-134.
40. Tandon S.K. Chelation in metal intoxication. VI. Influence of PAS and CDTA on the excretion of manganese in rabbits given MnO2. Toxicology 1978, 9:379-385.
41. Travers K.J., Patil C.K., Wodicka L., Lockhart D.J., Weissman J.S., Walter P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 2000, 101:249-258.
42. Vitte J., Traver S., Maues De Paula A., Lesage S., Rovelli G., Corti O., Duyckaerts C., Brice A. Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease. J. Neuropathol. Exp. Neurol. 2010, 69:959-972.
43. Welihinda A.A., Kaufman R.J. The unfolded protein response path way in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation. J. Biol. Chem. 1996, 271:18181-18187.
44. Yoon H., Kim D.S., Lee G.H., Kim J.Y., Kim D.H., Kim K.W., Chae S.W., You W.H., Lee Y.C., Park S.J., Kim H.R., Chae H.J. Protective effects of sodium para-amino salicylate on manganese-induced neuronal death: the involvement of reactive oxygen species. J. Pharm. Pharmacol. 2009, 61:1563-1569.