Inhibitory effects of rosmarinic acid on adriamycin-induced apoptosis in H9c2 cardiac muscle cells by inhibiting reactive oxygen species and the activations of c-Jun N-terminal kinase and extracellular signal-regulated kinase

Biochemical Pharmacology

Volumn 70, Issue 7, 2005, Pages 1066-1078

  Kim, Do Sung ^a   Kim, Hyung Ryong ^b   Woo, Eun Rhan ^c   Hong, Seong Tshool ^a   Chae, Han Jung ^a   Chae, Soo Wan ^a  

^a Chonbuk National University   (South Korea)

^b Wonkwang Biomaterial Implant Research Institute   (South Korea)

^c Chosun University   (South Korea)

Author keywords

Adriamycin; AP 1; Apoptosis; ERK; JNK; ROS; Rosmarinic acid

Indexed keywords

DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C FOS; REACTIVE OXYGEN METABOLITE; ROSMARINIC ACID; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CELL LINE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; HEART MUSCLE CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; STATISTICAL SIGNIFICANCE; TREATMENT INDICATION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CASPASE 3; CASPASES; CELL LINE; CINNAMATES; DEPSIDES; DNA PROBES; DOXORUBICIN; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUTATHIONE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE POTENTIALS; MITOCHONDRIA, HEART; MYOCARDIUM; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 24344438247     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.06.026     Document Type: Article

References (43)

1. S.K. Carter ADR-a review J Natl Cancer Inst 55 6 1975 1265 1274
2. S. Hitchcock-Bryan, R. Gelber, J.R. Cassady, and S.E. Sallan The impact of induction anthracycline on long-term failure-free survival in childhood acute lymphoblastic leukaemia Med Pediatr Oncol 14 4 1986 211 215
3. M. Zambetti, M. Terenziani, C. Bartoli, P. Valagussa, P. Piotti, and C. Ferranti Intermediate doses of cyclophosphamide alone or following ADR in advanced breast cancer. A pilot study Am J Clin Oncol 19 1 1996 82 86
4. D.K. Tack, F.M. Palmieri, and E.A. Perez Anthracycline vs nonanthracycline adjuvant therapy for breast cancer Oncology (Huntingt) 18 11 2004 1367 1376
5. P.K. Singal, and N. Iliskovic ADR-induced cardiomyopathy N Engl J Med 339 13 1998 900 905
6. S. Fogli, P. Nieri, and M.C. Breschi The role of nitric oxide in anthracycline toxicity and prospects for pharmacologic prevention of cardiac damage Federation Am Soc Exp Biol J 18 April (6) 2004 664 675
7. S. Kotamraju, E.A. Konorev, J. Joseph, and B. Kalyanaraman ADR-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species J Biol Chem 275 2000 33585 33592
8. V. Lee, A.K. Randhawa, and P.K. Singal ADR-induced myocardial dysfunction in vitro is mediated by free radicals Am J Physiol 261 4 Pt 2 1991 H989 H995
9. Q.Y. Liu, and B.K. Tan Effects of cis-unsaturated fatty acids on ADR sensitivity in P388/DOX resistant and P388 parental cell lines Life Sci 67 10 2000 1207 1218
10. I. Zupko, J. Hohmann, D. Redei, G. Falkay, G. Janicsak, and I. Mathe Antioxidant activity of leaves of Salvia species in enzyme-dependent and enzyme-independent systems of lipid peroxidation and their phenolic constituents Planta Med 67 4 2001 366 368
11. M.R. al-Sereiti, K.M. Abu-Amer, and P. Sen Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials Indian J Exp Biol 37 2 1999 124 130
12. H. Ito, T. Miyazaki, M. Ono, and H. Sakurai Antiallergic activities of rabdosiin and its related compounds: chemical and biochemical evaluations Bioorg Med Chem 6 7 1998 1051 1056
13. S. Chlopcikova, J. Psotova, P. Miketova, J. Sousek, V. Lichnovsky, and V. Simanek Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes. Part II. caffeic, chlorogenic and rosmarinic acids Phytother Res 18 5 2004 408 413
14. E.R. Woo, and M.S. Piao Antioxidative constituents from Lycopus lucidus Arch Pharm Res 27 2 2004 173 176
15. R.A. Winters, J. Zukowski, N. Ercal, R.H. Matthews, and D.R. Spitz Analysis of glutathione, glutathione disulfide, cysteine, homocysteine, and other biological thiols by high-performance liquid chromatography following derivatization by n-(1-pyrenyl)maleimide Anal Biochem 227 1 1995 14 21
16. V.R. Sutton, D.L. Vaux, and J.A. Trapani Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes J Immunol 158 12 1997 5783 5790
17. I. Budihardjo, H. Oliver, M. Lutter, X. Luo, and X. Wang Biochemical pathways of caspase activation during apoptosis Annu Rev Cell Dev Biol 15 1999 269 290
18. J.L. Zweier Measurement of superoxide-derived free radicals in the reperfused heart. Evidence for a free radical mechanism of reperfusion injury J Biol Chem 263 3 1998 1353 1357
19. N. Jiang, K.L. Dreher, J.A. Dye, Y. Li, J.H. Richards, and L.D. Martin Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig tracheal epithelial cells via an oxidant-mediated mechanism Toxicol Appl Pharmacol 163 3 2000 221 230
20. B.J. Pulverer, J.M. Kyriakis, J. Avruch, E. Nikolakaki, and J.R. Woodgett Phosphorylation of c-jun mediated by MAP kinases Nature 353 6345 1991 670 674
21. T. Smeal, B. Binetruy, D.A. Mercola, M. Birrer, and M. Karin Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73 Nature 354 6353 1991 494 496
22. M. Murakami, M. Ui, and H. Iba Fra-2-positive autoregulatory loop triggered by mitogen-activated protein kinase (MAPK) and Fra-2 phosphorylation sites by MAPK Cell Growth Differ 10 5 1999 333 342
23. L. Formigli, L. Ibba-Manneschi, A.M. Perna, C. Nediani, P. Liguori, and A. Tani Ischemia-reperfusion-induced apoptosis and p53 expression in the course of rat heterotopic heart transplantation Microvasc Res 56 3 1998 277 281
24. F.S. Shihab, T.F. Andoh, A.M. Tanner, H. Yi, and W.M. Bennett Expression of apoptosis regulatory genes in chronic cyclosporine nephrotoxicity favors apoptosis Kidney Int 56 6 1999 2147 2159
25. S. Wang, Z. Wang, L. Boise, P. Dent, and S. Grant Loss of the bcl-2 phosphorylation loop domain increases resistance of human leukemia cells (U937) to paclitaxel-mediated mitochondrial dysfunction and apoptosis Biochem Biophys Res Commun 259 1 1999 67 72
26. A. Geetha, R. Sankar, and C.S. Devi Effect of alpha-tocopherol on peroxidative membrane damage caused by ADR: an in vitro study in human erythrocytes Indian J Exp Biol 27 3 1989 274 278
27. Y.J. Kang, Y. Chen, and P.N. Epstein Suppression of ADR cardiotoxicity by overexpression of catalase in the heart of transgenic mice J Biol Chem 271 21 1996 12610 12616
28. H.C. Yen, T.D. Oberley, C.G. Gairola, L.I. Szweda, and D.K. St. Clair Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice Arch Biochem Biophys 362 1 1999 59 66
29. K.S. Kim, W.S. Moon, H.W. Song, J.H. Kim, and S.N. Cho A case of persistent endometriosis after total hysterectomy with both salpingo- oophorectomy managed by radiation therapy Arch Gynecol Obstet 265 4 2001 225 227
30. H.E. Mohamed, S.E. El-Swefy, and H.H. Hagar The protective effect of glutathione administration on ADR-induced acute cardiac toxicity in rats Pharmacol Res 42 2 2000 115 121
31. Y.J. Kang, Z.X. Zhou, G.W. Wang, A. Buridi, and J.B. Klein Suppression by metallothionein of ADR-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases J Biol Chem 275 18 2000 13690 13698
32. M.T. Osborn, and T.C. Chambers Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to ADR and other chemotherapeutic drugs J Biol Chem 271 48 1996 30950 30955
33. R. Yu, A.A. Shtil, T.H. Tan, I.B. Roninson, and A.N. Kong ADR activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis Cancer Lett 107 1 1996 73 81
34. W. Zhu, Y. Zou, R. Aikawa, K. Harada, S. Kudoh, and H. Uozumi MAPK superfamily plays an important role in daunomycin-induced apoptosis of cardiac myocytes Circulation 100 20 1999 2100 2107
35. T.L. Yue, C. Wang, J.L. Gu, X.L. Ma, S. Kumar, and J.C. Lee Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart Circ Res 86 6 2000 692 699
36. D. Tang, D. Wu, A. Hirao, J.M. Lahti, L. Liu, and B. Mazza ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53 J Biol Chem 277 15 2002 12710 12717
37. W. Woessmann, X. Chen, and A. Borkhardt Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines Cancer Chemother Pharmacol 50 5 2002 397 404
38. T. Minamino, T. Yujiri, P.J. Papst, E.D. Chan, G.L. Johnson, and N. Terada MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes Proc Natl Acad Sci USA 96 26 1999 15127 15132
39. P. Andreka, J. Zang, C. Dougherty, T.I. Slepak, K.A. Webster, and N.H. Bishopric Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis Circ Res 88 3 2001 305 312
40. K. Nobori, H. Ito, M. Tamamori-Adachi, S. Adachi, Y. Ono, and J. Kawauchi ATF3 inhibits ADR-induced apoptosis in cardiac myocytes: a novel cardioprotective role of ATF3 J Mol Cell Cardiol 34 10 2002 1387 1397
41. Y. Liu, J. Ludes-Meyers, Y. Zhang, D. Munoz-Medellin, H.T. Kim, and C. Lu Inhibition of AP-1 transcription factor causes blockade of multiple signal transduction pathways and inhibits breast cancer growth Oncogene 21 50 2002 7680 7689
42. P.H. Brown, R. Alani, L.H. Preis, E. Szabo, and M.J. Birrer Suppression of oncogene-induced transformation by a deletion mutant of c-jun Oncogene 8 4 1993 877 886
43. D.A. Liebermann, B. Gregory, and B. Hoffman AP-1 (Fos/Jun) transcription factors in hematopoietic differentiation and apoptosis Int J Oncol 12 3 1998 685 700