Manganese activates the mitochondrial apoptotic pathway in rat astrocytes by modulating the expression of proteins of the Bcl-2 family

Neurochemistry International

Volumn 53, Issue 6-8, 2008, Pages 408-415

  Gonzalez, Laura E ^a   Juknat, A Ana ^a   Venosa, Andrea J ^a   Verrengia, Noemi ^a   Kotler, Mónica L ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Apoptosis; Astrocytes; Bax; Bcl XL; Bcl XS; Manganese; Mitochondrial damage

Indexed keywords

CYTOCHROME C; EFFECTOR CASPASE; MANGANESE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ASTROCYTE; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; ASTROCYTES; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASES; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; MANGANESE; MANGANESE POISONING; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MODELS, BIOLOGICAL; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

RATTUS;

EID: 56349099220     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2008.09.008     Document Type: Article

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