Identification of a novel non-retinoid pan inverse agonist of the retinoic acid receptors

ACS Chemical Biology

Volumn 6, Issue 6, 2011, Pages 618-627

  Busby, Scott A ^a   Kumar, Naresh ^a   Kuruvilla, Dana S ^a   Istrate, Monica A ^a   Conkright, Juliana J ^a   Wang, Yongjun ^a   Kamenecka, Theodore M ^b   Cameron, Michael D ^a   Roush, William R ^b   Burris, Thomas P ^a   Griffin, Patrick R ^a  

^a Department of Molecular Therapeutics ^*  (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHYL) 1 PROPENYL]BENZOIC ACID; 4 [2 [5,6 DIHYDRO 5,5 DIMETHYL 8 (4 METHYLPHENYL) 2 NAPHTHYL]ETHYNYL]BENZOIC ACID; CYTOCHROME P450 26A1; MESSENGER RNA; RECEPTOR BLOCKING AGENT; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOIC ACID RECEPTOR INVERSE AGONIST; SR 0065; SR 1758; UNCLASSIFIED DRUG;

ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG RECEPTOR BINDING; GENE INDUCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

ANIMALS; CELL LINE; DIOXANES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LIGANDS; MICE; MOLECULAR STRUCTURE; QUINOLONES; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79961090114     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb100396s     Document Type: Conference Paper

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