메뉴 건너뛰기




Volumn 53, Issue 5, 2012, Pages 868-878

Suppression of adipose lipolysis by long-chain fatty acid analogs

Author keywords

AMPK; cAMP; Diabetes; Raf1

Indexed keywords

3,3,14,14 TETRAMETHYLHEXADECANEDIOIC ACID; ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; HORMONE SENSITIVE LIPASE; INSULIN; ISOPRENALINE; PERILIPIN; RAF PROTEIN; RAF1 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84860281134     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M022673     Document Type: Article
Times cited : (18)

References (35)
  • 3
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • DOI 10.1038/nrm2391, PII NRM2391
    • Guilherme, A., J. V. Virbasius, V. Puri, and M. P. Czech. 2008. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat. Rev. Mol. Cell Biol. 9: 367-377. (Pubitemid 351574198)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.5 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 4
    • 0018222938 scopus 로고
    • The role of free fatty acids in the regulation of lipolysis by human adipose tissue cells
    • Burns, T. W., P. E. Langley, B. E. Terry, and G. A. Robinson. 1978. The role of free fatty acids in the regulation of lipolysis by human adipose tissue cells. Metabolism. 27: 1755-1762. (Pubitemid 9085444)
    • (1978) Metabolism: Clinical and Experimental , vol.27 , Issue.12 , pp. 1755-1762
    • Burns, T.W.1    Langley, P.E.2    Terry, B.E.3    Robinson, G.A.4
  • 5
    • 0016703809 scopus 로고
    • Free fatty acids as feedback regulators of adenylate cyclase and cyclic 3′:5′-AMP accumulation in rat fat cells
    • Fain, J. N., and R. E. Shepherd. 1975. Free fatty acids as feedback regulators of adenylate cyclase and cyclic 3′:5′-AMP accumulation in rat fat cells. J. Biol. Chem. 250: 6586-6592.
    • (1975) J. Biol. Chem. , vol.250 , pp. 6586-6592
    • Fain, J.N.1    Shepherd, R.E.2
  • 6
    • 36148956577 scopus 로고    scopus 로고
    • Interaction of the adipocyte fatty acid-binding protein with the hormone-sensitive lipase: Regulation by fatty acids and phosphorylation
    • DOI 10.1074/jbc.M703730200
    • Smith, A. J., B. R. Thompson, M. A. Sanders, and D. A. Bernlohr. 2007. Interaction of the adipocyte fatty acid-binding protein with the hormone-sensitive lipase: regulation by fatty acids and phosphorylation. J. Biol. Chem. 282: 32424-32432. (Pubitemid 350106440)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.44 , pp. 32424-32432
    • Smith, A.J.1    Thompson, B.R.2    Sanders, M.A.3    Bernlohr, D.A.4
  • 7
    • 47749085114 scopus 로고    scopus 로고
    • AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: Potential mechanism and physiological relevance
    • Gauthier, M. S., H. Miyoshi, S. C. Souza, J. M. Cacicedo, A. K. Saha, A. S. Greenberg, and N. B. Ruderman. 2008. AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance. J. Biol. Chem. 283: 16514-16524.
    • (2008) J. Biol. Chem. , vol.283 , pp. 16514-16524
    • Gauthier, M.S.1    Miyoshi, H.2    Souza, S.C.3    Cacicedo, J.M.4    Saha, A.K.5    Greenberg, A.S.6    Ruderman, N.B.7
  • 8
    • 0022256692 scopus 로고
    • 22, alpha,omega-dicarboxylic acids in the rat in vivo
    • Bar-Tana, J., G. Rose-Kahn, and M. Srebnik. 1985. Inhibition of lipid synthesis by beta beta'-tetramethyl-substituted, C14-C22, alpha, omega-dicarboxylic acids in the rat in vivo. J. Biol. Chem. 260: 8404-8410. (Pubitemid 15249849)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.14 , pp. 8404-8410
    • Bar-Tana, J.1    Rose-Kahn, G.2    Srebnik, M.3
  • 9
    • 0023949437 scopus 로고
    • Hypolipidemic effect of beta, beta'-methyl-substituted hexadecanedioic acid (MEDICA 16) in normal and nephrotic rats
    • Bar-Tana, J., G. Rose-Kahn, B. Frenkel, Z. Shafer, and M. Fainaru. 1988. Hypolipidemic effect of beta, beta'-methyl-substituted hexadecanedioic acid (MEDICA 16) in normal and nephrotic rats. J. Lipid Res. 29: 431-441.
    • (1988) J. Lipid Res. , vol.29 , pp. 431-441
    • Bar-Tana, J.1    Rose-Kahn, G.2    Frenkel, B.3    Shafer, Z.4    Fainaru, M.5
  • 10
    • 0030773514 scopus 로고    scopus 로고
    • Sensitization to insulin induced by beta,beta'-methyl-substituted hexadecanedioic acid (MEDICA 16) in obese Zucker rats in vivo
    • Mayorek, N., B. Kalderon, E. Itach, and J. Bar-Tana. 1997. Sensitization to insulin induced by beta,beta'-methyl-substituted hexadecanedioic acid (MEDICA 16) in obese Zucker rats in vivo. Diabetes. 46: 1958-1964. (Pubitemid 27512080)
    • (1997) Diabetes , vol.46 , Issue.12 , pp. 1958-1964
    • Mayorek, N.1    Kalderon, B.2    Itach, E.3    Bar-Tana, J.4
  • 11
    • 0029016886 scopus 로고
    • Inhibition of atherosclerosis and myocardial lesions in the JCR:LA-cp rat by beta, beta'-tetramethylhexadecanedioic acid (MEDICA 16)
    • Russell, J. C., R. M. Amy, S. E. Graham, P. J. Dolphin, G. O. Wood, and J. Bar-Tana. 1995. Inhibition of atherosclerosis and myocardial lesions in the JCR:LA-cp rat by beta, beta'-tetramethylhexadecanedioic acid (MEDICA 16). Arterioscler. Thromb. Vasc. Biol. 15: 918-923.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 918-923
    • Russell, J.C.1    Amy, R.M.2    Graham, S.E.3    Dolphin, P.J.4    Wood, G.O.5    Bar-Tana, J.6
  • 13
    • 0036317639 scopus 로고    scopus 로고
    • Modulation by nutrients and drugs of liver acyl-CoAs analyzed by mass spectrometry
    • DOI 10.1194/jlr.M200060-JLR200
    • Kalderon, B., V. Sheena, S. Shachrur, R. Hertz, and J. Bar-Tana. 2002. Modulation by nutrients and drugs of liver acyl-CoAs analyzed by mass spectrometry. J. Lipid Res. 4 3: 1125-1132. (Pubitemid 34760884)
    • (2002) Journal of Lipid Research , vol.43 , Issue.7 , pp. 1125-1132
    • Kalderon, B.1    Sheena, V.2    Shachrur, S.3    Hertz, R.4    Bar-Tana, J.5
  • 15
    • 0037205494 scopus 로고    scopus 로고
    • Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments
    • DOI 10.1074/jbc.M111807200
    • Balla, A., G. Tuymetova, M. Barshishat, M. Geiszt, and T. Balla. 2002. Characterization of type II phosphatidylinositol 4-kinase isoform reveals association of the enzymes with endosomal vesicular compartments. J. Biol. Chem. 277: 20041-20050. (Pubitemid 34967528)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.22 , pp. 20041-20050
    • Balla, A.1    Tuymetova, G.2    Barshishat, M.3    Geiszt, M.4    Balla, T.5
  • 16
    • 67649736512 scopus 로고    scopus 로고
    • Regulation of visceral and subcutaneous adipocyte lipolysis by acute AICAR-induced AMPK activation
    • Anthony, N. M., M. P. Gaidhu, and R. B. Ceddia. 2009. Regulation of visceral and subcutaneous adipocyte lipolysis by acute AICAR-induced AMPK activation. Obesity (Silver Spring). 17: 1312-1317.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1312-1317
    • Anthony, N.M.1    Gaidhu, M.P.2    Ceddia, R.B.3
  • 18
    • 0028073143 scopus 로고
    • Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase
    • DOI 10.1016/0014-5793(94)01006-4
    • Sullivan, J. E., K. J. Brocklehurst, A. E. Marley, F. Carey, D. Carling, and R. K. Ber. 1994. Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS Lett. 353: 33-36. (Pubitemid 24312538)
    • (1994) FEBS Letters , vol.353 , Issue.1 , pp. 33-36
    • Sullivan, J.E.1
  • 19
    • 33847072201 scopus 로고    scopus 로고
    • AMP-activated protein kinase as a drug target
    • Hardie, D. G. 2007. AMP-activated protein kinase as a drug target. Annu. Rev. Pharmacol. Toxicol. 47: 185-210.
    • (2007) Annu. Rev. Pharmacol. Toxicol. , vol.47 , pp. 185-210
    • Hardie, D.G.1
  • 21
    • 2342541774 scopus 로고    scopus 로고
    • Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase
    • DOI 10.1016/j.bcp.2004.01.020, PII S0006295204000632
    • Saitoh, M., K. Nagai, K. Nakagawa, T. Yamamura, S. Yamamoto, and T. Nishizaki. 2004. Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase. Biochem. Pharmacol. 67: 2005-2011. (Pubitemid 38591388)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.10 , pp. 2005-2011
    • Saitoh, M.1    Nagai, K.2    Nakagawa, K.3    Yamamura, T.4    Yamamoto, S.5    Nishizaki, T.6
  • 22
    • 0022472556 scopus 로고
    • The effects of an adenylate cyclase inhibitor on the electrophysiological correlates of neuromuscular transmission in the frog
    • Silinsky, E. M., and S. M. Vogel. 1986. The effects of an adenylate cyclase inhibitor on the electrophysiological correlates of neuromuscular transmission in the frog. Br. J. Pharmacol. 88: 799-805.
    • (1986) Br. J. Pharmacol. , vol.88 , pp. 799-805
    • Silinsky, E.M.1    Vogel, S.M.2
  • 24
    • 11244325007 scopus 로고    scopus 로고
    • Protein kinase C and epidermal growth factor stimulation of Raf1 potentiates adenylyl cyclase type 6 activation in intact cells
    • DOI 10.1124/mol.104.001370
    • Beazely, M. A., J. K. Alan, and V. J. Watts. 2005. Protein kinase C and epidermal growth factor stimulation of Raf1 potentiates adenylyl cyclase type 6 activation in intact cells. Mol. Pharmacol. 67: 250-259. (Pubitemid 40069985)
    • (2005) Molecular Pharmacology , vol.67 , Issue.1 , pp. 250-259
    • Beazely, M.A.1    Alan, J.K.2    Watts, V.J.3
  • 26
    • 34447099952 scopus 로고    scopus 로고
    • New insights into the regulation of cAMP synthesis beyond GPCR/G protein activation: Implications in cardiovascular regulation
    • DOI 10.1016/j.lfs.2007.05.015, PII S0024320507004134
    • Feldman, R. D., and R. Gros. 2007. New insights into the regulation of cAMP synthesis beyond GPCR/G protein activation: implications in cardiovascular regulation. Life Sci. 81: 267-271. (Pubitemid 47030574)
    • (2007) Life Sciences , vol.81 , Issue.4 , pp. 267-271
    • Feldman, R.D.1    Gros, R.2
  • 29
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • DOI 10.1126/science.1128294
    • Ozcan, U., E. Yilmaz, L. Ozcan, M. Furuhashi, E. Vaillancourt, R. O. Smith, C. Z. Gorgun, and G. S. Hotamisligil. 2006. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 313: 1137-1140. (Pubitemid 44300242)
    • (2006) Science , vol.313 , Issue.5790 , pp. 1137-1140
    • Ozcan, U.1    Yilmaz, E.2    Ozcan, L.3    Furuhashi, M.4    Vaillancourt, E.5    Smith, R.O.6    Gorgun, C.Z.7    Hotamisligil, G.S.8
  • 30
    • 34248189053 scopus 로고    scopus 로고
    • CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation
    • DOI 10.1194/jlr.M600493-JLR200
    • Yamaguchi, T., N. Omatsu, E. Morimoto, H. Nakashima, K. Ueno, T. Tanaka, K. Satouchi, F. Hirose, and T. Osumi. 2007. CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation. J. Lipid Res. 48: 1078-1089. (Pubitemid 46708675)
    • (2007) Journal of Lipid Research , vol.48 , Issue.5 , pp. 1078-1089
    • Yamaguchi, T.1    Omatsu, N.2    Morimoto, E.3    Nakashima, H.4    Ueno, K.5    Tanaka, T.6    Satouchi, K.7    Hirose, F.8    Osumi, T.9
  • 31
    • 58849137050 scopus 로고    scopus 로고
    • Mechanisms of metformin inhibiting lipolytic response to isoproterenol in primary rat adipocytes
    • Zhang, T., J. He, C. Xu, L. Zu, H. Jiang, S. Pu, X. Guo, and G. Xy. 2009. Mechanisms of metformin inhibiting lipolytic response to isoproterenol in primary rat adipocytes. J. Mol. Endocrinol. 42: 57-66.
    • (2009) J. Mol. Endocrinol. , vol.42 , pp. 57-66
    • Zhang, T.1    He, J.2    Xu, C.3    Zu, L.4    Jiang, H.5    Pu, S.6    Guo, X.7    Xy, G.8
  • 32
    • 3042761443 scopus 로고    scopus 로고
    • Medium-chain fatty acids attenuate agonist-stimulated lipolysis, mimicking the effects of starvation
    • Lei, T., W. Xie, J. Han, B. E. Corkey, J. A. Hamilton, and W. Guo. 2004. Medium-chain fatty acids attenuate agonist-stimulated lipolysis, mimicking the effects of starvation. Obes. Res. 12: 599-611. (Pubitemid 41132502)
    • (2004) Obesity Research , vol.12 , Issue.4 , pp. 599-611
    • Lei, T.1    Xie, W.2    Han, J.3    Corkey, B.E.4    Hamilton, J.A.5    Guo, W.6
  • 33
    • 0242384915 scopus 로고    scopus 로고
    • Role of AMP-activated Protein Kinase in Cyclic AMP-dependent Lipolysis in 3T3-L1 Adipocytes
    • DOI 10.1074/jbc.M308484200
    • Yin, W., J. Mu, and M. J. Birnbaum. 2003. Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis in 3T3-L1 adipocytes. J. Biol. Chem. 278: 43074-43080. (Pubitemid 37345923)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.44 , pp. 43074-43080
    • Yin, W.1    Mu, J.2    Birnbaum, M.J.3
  • 34
    • 34247853279 scopus 로고    scopus 로고
    • Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes
    • DOI 10.1042/BJ20061479
    • Koh, H. J., M. F. Hirshman, H. He, Y. Li, Y. Manabe, J. A. Balschi, and L. J. Goodyear. 2007. Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes. Biochem. J. 403: 473-481. (Pubitemid 46706975)
    • (2007) Biochemical Journal , vol.403 , Issue.3 , pp. 473-481
    • Koh, H.-J.1    Hirshman, M.F.2    He, H.3    Li, Y.4    Manabe, Y.5    Balschi, J.A.6    Goodyear, L.J.7
  • 35
    • 60549083066 scopus 로고    scopus 로고
    • Regulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis
    • Omar, B., E. Zmuda-Trzebiatowska, V. Manganiello, O. Goransson, and E. Degerman. 2009. Regulation of AMP-activated protein kinase by cAMP in adipocytes: roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis. Cell. Signal. 21: 760-766.
    • (2009) Cell. Signal. , vol.21 , pp. 760-766
    • Omar, B.1    Zmuda-Trzebiatowska, E.2    Manganiello, V.3    Goransson, O.4    Degerman, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.