Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway

Immunology

Volumn 136, Issue 2, 2012, Pages 153-162

  Ichikawa, Riko ^a   Takayama, Tetsuro ^a   Yoneno, Kazuaki ^a   Kamada, Nobuhiko ^a   Kitazume, Mina T ^a   Higuchi, Hajime ^a   Matsuoka, Katsuyoshi ^a   Watanabe, Mitsuhiro ^b   Itoh, Hiroshi ^a   Kanai, Takanori ^a   Hisamatsu, Tadakazu ^a   Hibi, Toshifumi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Bile acid; CAMP; Dendritic cell differentiation; Interleukin 12; TGR5

Indexed keywords

8 BROMO CYCLIC AMP; BACTERIAL ANTIGEN; BILE ACID; CELL NUCLEUS RECEPTOR; CYCLIC AMP; FARNESOID X RECEPTOR; HORMONE RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 12P70; MEMBRANE RECEPTOR; PROTEIN TGR5; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIGEN PRESENTING CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSTIMULATION; INNATE IMMUNITY; LYMPH NODE; MONOCYTE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; BILE ACIDS AND SALTS; CELL DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; DOWN-REGULATION; HUMANS; INTERLEUKIN-12; LEUKOCYTES, MONONUCLEAR; RECEPTORS, G-PROTEIN-COUPLED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84860253913     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2012.03554.x     Document Type: Article

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