Promotion of a functional B cell germinal center response after leishmania species Co-infection is associated with lesion resolution

American Journal of Pathology

Volumn 180, Issue 5, 2012, Pages 2009-2017

  Gibson Corley, Katherine N ^a,b   Boggiatto, Paola M ^a   Bockenstedt, Marie M ^a   Petersen, Christine A ^a   Waldschmidt, Thomas J ^b   Jones, Douglas E ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD45 ANTIGEN; CD86 ANTIGEN; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN G2C ANTIBODY; IMMUNOGLOBULIN M; INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; LECTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FOOT PAD; GERMINAL CENTER; IMMUNE RESPONSE; IN VITRO STUDY; LEISHMANIA; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE; MEMORY CELL; MIXED INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WOUND HEALING;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; B-LYMPHOCYTES; COINFECTION; FEMALE; GERMINAL CENTER; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; IMMUNOLOGIC MEMORY; INTERLEUKINS; LEISHMANIA MAJOR; LEISHMANIA MEXICANA; LEISHMANIASIS, CUTANEOUS; LYMPH NODES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; PROGNOSIS; RECEPTORS, INTERLEUKIN-21; SPECIES SPECIFICITY;

EID: 84860236401     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.01.012     Document Type: Article

References (27)

1. L.C. Afonso, P. Scott Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis Infect Immun 61 1993 2952 2959
2. A.E. Ramer, Y.F. Vanloubbeeck, D.E. Jones Antigen-responsive CD4+ T cells from C3H mice chronically infected with Leishmania amazonensis are impaired in the transition to an effector phenotype Infect Immun 74 2006 1547 1554
3. Y. Vanloubbeeck, D.E. Jones Protection of C3HeB/FeJ mice against Leishmania amazonensis challenge after previous Leishmania major infection Am J Trop Med Hyg 71 2004 407 411
4. P. Veras, C. Brodskyn, F. Balestieri, L. Freitas, A. Ramos, A. Queiroz, A. Barral, S. Beverley, M. Barral-Netto A dhfr-ts- Leishmania major knockout mutant cross-protects against Leishmania amazonensis Mem Inst Oswaldo Cruz 94 1999 491 496
5. R. Mukbel, C.A. Petersen, D.E. Jones Soluble factors from Leishmania major-specific CD4(+)T cells and B cells limit L. amazonensis amastigote survival within infected macrophages Microbes Infect 8 2006 2547 2555
6. K.N. Gibson-Corley, P.M. Boggiatto, R.M. Mukbel, C.A. Petersen, D.E. Jones A deficiency in the B cell response of C57BL/6 mice correlates with loss of macrophage-mediated killing of Leishmania amazonensis Int J Parasitol 40 2010 157 161
7. D.E. Jones, M.R. Ackermann, U. Wille, C.A. Hunter, P. Scott Early enhanced Th1 response after Leishmania amazonensis infection of C57BL/6 interleukin-10-deficient mice does not lead to resolution of infection Infect Immun 70 2002 2151 2158
8. K.L. Wolniak, S.M. Shinall, T.J. Waldschmidt The germinal center response Crit Rev Immunol 24 2004 39 65
9. J.L. Rabinowitz, V.K. Tsiagbe, M.H. Nicknam, G.J. Thorbecke Germinal center cells are a major IL-5-responsive B cell population in peripheral lymph nodes engaged in the immune response J Immunol 145 1990 2440 2447
10. C.L. Cozine, K.L. Wolniak, T.J. Waldschmidt The primary germinal center response in mice Curr Opin Immunol 17 2005 298 302
11. L. Leifeld, C. Trautwein, F.L. Dumoulin, M.P. Manns, T. Sauerbruch, U. Spengler Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure Am J Pathol 154 1999 1711 1720
12. C.D. Allen, T. Okada, J.G. Cyster Germinal-center organization and cellular dynamics Immunity 27 2007 190 202
13. R.M. Martin, J.L. Brady, A.M. Lew The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice J Immunol Methods 212 1998 187 192
14. J.S. Yi, M.A. Cox, A.J. Zajac Interleukin-21: a multifunctional regulator of immunity to infection Microbes and Infection 12 2010 1111 1119
15. N.M. Haynes Follicular associated T cells and their B-cell helper qualities Tissue Antigens 71 2008 97 104
16. D. Eto, C. Lao, D. DiToro, B. Barnett, T.C. Escobar, R. Kageyama, I. Yusuf, S. Crotty IL-21 and IL-6 are critical for diferent aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation PLoS One 6 2011 17739
17. N. Fazilleau, L. Mark, L.J. McHeyzer-Williams, M.G. McHeyzer-Williams Follicular helper T cells: lineage and location Immunity 30 2009 324 335
18. V. Kalia, S. Sarkar, T.S. Gourley, B.T. Rouse, R. Ahmed Differentiation of memory B and T cells Curr Opin Immunol 18 2006 255 264
19. A.L. Abreu-Silva, K.S. Calabrese, S.M. Cupolilo, F.O. Cardoso, C.S. Souza, S.C. Goncalves da Costa Histopathological studies of visceralized Leishmania (Leishmania) amazonensis in mice experimentally infected Vet Parasitol 121 2004 179 187
20. R.L. Reinhardt, H.E. Liang, R.M. Locksley Cytokine-secreting follicular T cells shape the antibody repertoire Nat Immunol 10 2009 385 393
21. S.A. Miles, S.M. Conrad, R.G. Alves, S.M. Jeronimo, D.M. Mosser A role for IgG immune complexes during infection with the intracellular pathogen Leishmania J Exp Med 201 2005 747 754
22. N. Wanasen, L. Xin, L. Soong Pathogenic role of B cells and antibodies in murine Leishmania amazonensis infection Int J Parasitol 38 2008 417 42930
23. L.U. Buxbaum A detrimental role for IgG and Fc gammaR in Leishmania mexicana infection Immunol Res 42 2008 197 209
24. P.E. Kima, S.L. Constant, L. Hannum, M. Colmenares, K.S. Lee, A.M. Haberman, M.J. Shlomchik, D. McMahon-Pratt Internalization of Leishmania mexicana complex amastigotes via the Fc receptor is required to sustain infection in murine cutaneous leishmaniasis J Exp Med 191 2000 1063 1068
25. B.N. Thomas, L.U. Buxbaum FcgammaRIII mediates immunoglobulin G-induced interleukin-10 and is required for chronic Leishmania mexicana lesions Infect Immun 76 2008 623 631
26. P. Scott, P. Natovitz, A. Sher B lymphocytes are required for the generation of T cells that mediate healing of cutaneous leishmaniasis J Immunol 137 1986 1017 1021
27. F. Woelbing, S.L. Kostka, K. Moelle, Y. Belkaid, C. Sunderkoetter, S. Verbeek, A. Waisman, A.P. Nigg, J. Knop, M.C. Udey, E. von Stebut Uptake of Leishmania major by dendritic cells is mediated by Fc gamma receptors and facilitates acquisition of protective immunity J Exp Med 203 2006 177 188